• Journal of Acupuncture Research
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• v.19 no.6
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• pp.49-60
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• 2002

Objective : The aim of this experiment is to investigate the effect of acupuncture and moxibustion at SP6(Sanyinjiao) and BL28(Pangguanshu) on uranyl acetate-induced acute renal failure in rats. Methods : To induce experimental acute renal failure, uranyl acetate was intraperitoneally injected to rats by 5mg/kg. 3 days later acupuncture and moxibustion treatment was done at SP6(Sanyinjiao) and BL28(Pangguanshu) bilaterally of the rats. And then 4 days later, we measured rats' body weight, kidney weight, serum BUN, creatinine and serum eletrolyte levels(Na, K and Cl). Results : In the moxibustion group, hypertrophy index of kidney and serum BUN level were decreased marginally significantly, and serum creatinine, K levels were decreased significantly. But in the acupuncture group, there was no significance at this experiment. Conclusions : SP6(Sanyinjiao) and BL28(Pangguanshu) moxibustion can decrease serum BUN, creatinine, and serum eletrolyte levels on uranyl acetate-induced acute renal failure in rats. And the study will be done continuously about non-effect in the acupuncture group at this experiment.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.19 no.4
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• pp.491-497
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• 2010

The magnetic polishing is the useful method to finish some machinery fabrications by using magnetic power. This method is one of the precision techniques and has an aim for clean technology in the clean pipes. The magnetic abrasive polishing method is not so common in the field of machine that it is not known to widely. There are rarely researcher in this field because of non-effectiveness of magnetic abrasive. This paper deals with mediocritizing magnetic polishing device into regular lathe and this experiment was conducted in order to get the best surface roughness at low cost. This paper contains the result of experiment to acquire the best surface roughness, not using the high-cost polishing material in processing. In this paper, We could have investigated into the changes of the movement of magnetic abrasive grain. In reference to this result, we could have made the experiment which is set under the condition of the magnetic flux density, polishing velocity according to the form of magnetic brush.

• The Journal of Korean Obstetrics and Gynecology
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• v.36 no.1
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• pp.35-53
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• 2023

Objectives: The aim of this study is to investigate the research trends of animal experiment on the herbal medicine treatment for endometriosis over the past 10 years. Methods: We searched the databases (Pubmed, Embase, Science-on) with terms as endometriosis, Korean medicine, herbal medicine and Chinese medicine. Among the results, we reviewed studies published from 2013 to 2022. Results: 26 studies were selected and analyzed. 8 single herbs and 18 complex formula were used in these studies. The most commonly used herbal medicine for endometriosis was Paeoniae Radix. Each studies showed that herbal medicine had significant effect on treating endometriosis. Conclusions: These results suggest that treating endometriosis with herbal material is effective in inhibiting ectopic lesion and angiogenesis, increasing pain threshold and apoptosis. Further research should be conducted to verify its therapeutic mechanisms and effectiveness.

• Journal of Korean Physical Therapy Science
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• v.28 no.2
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• pp.1-9
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• 2021

Background: The requirements for postural and motor control in backward walking training (BWT) may improve balance and walking speed in patients with acute stroke. The aim of this study was to analyze the effect of BWT on balance, balance confidence, and fall efficacy in this population. Design: Randomized controlled pilot trial. Methods: This study included 14 subjects with acute stroke (onset of illness less than one month). They were randomly allocated to a BWT (n=7) or forward walking training (n=7) group and observed five times in a week for a period of two weeks. Measurements were taken before and after the experiment using the Berg balance scale (BBS), Activities-specific balance confidence scale (ABC), and Fall efficacy scale (FES). Results: The BBS, ABC and FES scores obtained in both groups after the experiment were significantly higher than those before the experiment (p<0.05). In addition, the BBS, ABC, and FES scores in the experimental group were significantly higher than those in the control group (p<0.05). Conclusion: These findings indicate that BWT improved balance and balance confidence and decreased the risks of fall in patients with acute stroke. Further study is needed to better understand the effects of backward walking in acute stroke patients.

• Journal of The Korean Association For Science Education
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• v.28 no.4
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• pp.331-339
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• 2008

The aim of this study was to compare the effectiveness of microcomputer-based laboratory (MBL) with the traditional laboratory experiment on science classes in middle school. MBL tools were developed and applied for five experiment subjects chosen from middle school science textbook for MBL experiment classes, while usual experiment methods suggested in the textbook were used in traditional experiment classes. In order to evaluate the effects of MBL experiment class, achievement, graphic ability, science process skills, affective aspect related to science were tested before and after applying the MBL experiment. The result revealed that MBL experiment class was more effective than traditional experiment class in improving student's science achievement, science process skills, and graphic ability. The result also indicated that there was a significant difference between experiment and control group with regards to the effect on affective aspect related to science. From the above result, we can find the positive implication of applicability of MBL experiment as a new experiment tool at the early stage of introduction in a real context.

• Proceedings of the Korean Statistical Society Conference
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• 2002.05a
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• pp.79-83
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• 2002

Since its introduction in 1995 by Schena et al. cDNA microarrays have been established as a potential tool for high-throughput analysis which allows the global monitoring of expression levels for thousands of genes simultaneously. One of the characteristics of the cDNA microarray data is that there is inherent noise even after the removal of systematic effects in the experiment. Therefore, replication is crucial to the microarray experiment. The assessment of reproducibility among replicates, however, has drawn little attention. Reproducibility may be assessed with several different endpoints along the process of data reduction of the microarray data. We define the reproducibility to be the degree with which replicate arrays duplicate each other. The aim of this note is to develop a novel measure of reproducibility among replicates in the cDNA microarray experiment based on the unprocessed data. Suppose we have p genes and n replicates in a microarray experiment. We first develop a measure of reproducibility between two replicates and generalize this concept for a measure of reproducibility of one replicate against the remaining n-1 replicates. We used the rank of the outcome variable and employed the concept of a measure of tracking in the blood pressure literature. We applied the reproducibility measure to two sets of microarray experiments in which one experiment was performed in a more homogeneous environment, resulting in validation of this novel method. The operational interpretation of this measure is clearer than Pearson's correlation coefficient which might be used as a crude measure of reproducibility of two replicates.

• Journal of Educational Research in Mathematics
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• v.15 no.3
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• pp.353-374
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• 2005

Recently, there have been many changes in researches of mathematics education. There is a growing number of researchers who are interested in empirical researches. According to the these changes, there is also an emphasis on methodology of mathematics education. This means that many researchers try to conduct an research using scientific approach. Therefore, new types of research developing mathematics courses recently has evolved as follows: teaching experiment, hypothetical loaming trajectory, design science, developmental research. The aim of this study is to reflect on developmental research in RME and to induce desirable directions for developing our mathematics courses. In order to attain these purposes, the present paper reflects the philosophy of RME, aim, procedure, data collection, data analysis, and justification of developmental research with illustrating a exemplar Based on these reflections, it is discussed that it needs to construct the mathematics curriculum connecting theory and practice in mathematics education, to report the process of developing mathematics courses faithfully, and to develop real mathematics courses after conducting basic developmental researches in order to take scientific app- roaches for developing mathematics courses.

• Korean Chemical Engineering Research
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• v.46 no.4
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• pp.756-763
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• 2008

The aim of this work was to obtain uniform and well-dispersed spherical silver nanoparticles using statistical design-of-experiment methods. We performed the experiments using 2 k fractional factorial designs with respect to key factors of a general chemical reduction method. The nanoparticles prepared were characterized by SEM, TEM and UV-visible absorbance for particle size, distribution, aggregation and anisotropy. The data obtained were analyzed and optimized using a statistical software, Minitab. The design-of-experiment methods using quantified data enabled us to determine key factors and appreciate interactions between factors. The measured properties of nanoparticles were dominated not only by individual one or two main factors but also by interactions between factors. The appropriate combination of the factors produced small, narrow-distributed and non-aggregated silver nanoparticles of about 30 nm with approximately 10% standard deviation.

• Korean Journal of Agricultural Science
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• v.38 no.2
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• pp.257-262
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• 2011

The aim of this study was to identify the polymorphism on fatty acid synthase (FASN) gene and its association with fat traits and fatty acid composition in Hanwoo. We genotyped a SNP (g.16024G${\rightarrow}$A) detected in Exon34 of FASN on 90 Hanwoo steers by PCR RFLP. A linear mixed model revealed an association of g.16024G${\rightarrow}$A with total body fat contents (P=0.006), while there is no significant effect between g.16024G${\rightarrow}$A and other traits (IMF, BF and fatty acid composition). Regression coefficient and $R^2$ of the SNP was -1.5 kg and 0.36 in this anslysis. Expecially, AA type of g.16024G${\rightarrow}$A bas a less amount of body fat (1.5 kg) than GG type of the SNP in Hanwoo. In conclusion, this study indicates an important role for FASN gene in determining body fat content in Hanwoo.

• Journal of The Korean Association For Science Education
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• v.27 no.1
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• pp.59-69
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• 2007

The aim of this study was to investigate teachers' perceptions on MBL (microcomputer-based laboratory) experiment training program for teachers, the expecting effects of MBL experiment and application of MBL experiment after conducting MBL experiment training for science classes in schools. This study showed that most of the teachers who participated in the training program thought that the MBL experiment training program was very useful and instructive. Many teachers considered that MBL experiments using a computer could decrease time spent in the experiment by accurate and fast data collection and analysis. They also thought that the reduced time could be used more effectively in the analysis of experimental data and discussion activities leading to correct concept formation as well as in the development of graphical analysis and science process skills. However, they thought that MBL experiments were ineffective in learning how to operate experiment apparatus. This study also revealed that most teachers intended to apply MBL experiments in real classrooms context right after the training course and they pointed out many obstacles in introducing MBL experiments into their classrooms such as a budget to purchase equipment, poor laboratory conditions, and few MBL experiment training opportunities. In order to apply MBL experiment into the real classrooms, further changes were suggested as follows; development of technologies to reduce unit cost of equipment for MBL experiments, production and supply of many kinds of sensors, development of MBL experiment materials, and expansion of the training program for teachers.