• Journal of KIISE:Information Networking
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• v.35 no.4
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• pp.301-310
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• 2008

In the existing literature, the handover process reveals numerous problems manifested by high movement detection latency. FMIPv6 can reduce packet loss using a tunnel-based handover mechanism. However, this mechanism may cause performance degradation due to the out-of-sequence packets. Recently. Proxy Mobile IPv6 is proposed for network-based mobility management to reduce overhead in mobile node. PMIPv6 can decrease handover latency which related overhead in MN by using network agent. In this paper, we proposed optimized fast handover scheme called Fast Proxy Mobile IPv6 (EF-PMIPv6). The proposed EF-PMIPv6 can support fast handover using fast IAPP and ND schemes. Further, a mathematical analysis is provided to show the benefits of our scheme. In the analysis, various parameters are used to compare our scheme with the current procedures, while our approach focuses on the reduction of handover latency.

• Korean Journal of Pharmacognosy
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• v.48 no.1
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• pp.38-45
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• 2017

Black-red ginseng (BRGP) exhibits more potent biological activities than white and red ginseng. However, the effect of BRGP on allergic inflammation has not been studied extensively. In this study, we attempted to evaluate the effects of BRGP on allergic inflammation in vitro and in vivo. The effects of BRGP on pro-inflammatory mediators in phorbol myristate acetate (PMA) and A23187-stimulated human mast cells (HMC-1) and on trimellitic anhydride (TMA)-induced atopic dermatitis-like skin lesions in BALB/c mice were evaluated. BRGP suppressed the expression of $TNF-{\alpha}$, IL-6 and IL-8 from HMC-1 stimulated with PMA and A23187. Furthermore, the oral administration of BRGP markedly significantly reduced apparent severity of atopic dermatitis-like skin lesions, ear swelling, lymph node weight gains and serum IgE levels induced by TMA in mice. BRGP treatment also ameliorated epidermal hyperplasia and infiltration of inflammatory cells including mast cells. Taken together, BRGP possesses significant anti-atopic efficacy, suggesting that it could be used as a potential therapeutic agent for allergic inflammatory diseases, including atopic dermatitis.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.39C no.8
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• pp.674-680
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• 2014

In this paper, as one of the fusion of IT and ocean technology, we propose a scheme to support NEMO in a harbor area network to provide network mobility for passengers, distribution as well as give a connection to an MN from an outside network. In a harbor area under PMIPv6 with NEMO support, a problem could be occurred due to overlapping HA/LMA tunnels and duplicate BCE fields. To Solve these problems, we consider the existing mobility option and add an optional field in the PBU message, which can notify the LMA and HA for either an initial connection or handover request. This procedure can reduce some overlapped steps of binding procedure. Hence, our proposed scheme could reduce an amount of delay and save the processing resource in the harbor area under PMIPv6 with NEMO support.

• Korean Journal of Veterinary Research
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• v.51 no.3
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• pp.203-208
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• 2011

Postweaning multisystemic wasting syndrome (PMWS), which was first identified in western Canada in 1991 and more recently in the United States, Europe and Asia, is an emerging disease in pigs. Porcine circovirus type 2 (PCV-2) is the primary infectious viral agent causing PMWS, but the full expression of the disease may require the presence of other agents. It is reported that there is apparent synergism between PCV-2 and porcine parvovirus (PPV) in increasing the severity of the clinical signs and lesions of PMWS. From January 2006 to May 2008, a total of the 154 lymph node samples were collected from 4~12 weeks old pigs which had been submitted to the College of Veterinary Medicine, Jeju National University, Korea. These pigs were diagnosed as PMWS on the basis of clinical and pathological examination from 48 commercial herds in Jeju Island. Based on the immunohistochemistry, porcine parvovirus was detected in 69 cases (44.8%) from 154 weaned or grower pigs. PPV antigens were detected in the cytoplasm of histiocytic cells multifocally infiltrated in the cortex and paracortex of lymph nodes. The results of this study clarify that PPV is prevalent in pigs with PMWS on Jeju Island. Therefore PPV is one of the most important co-agents in the development of naturally acquired PMWS. This study may be helpful to the control of this disease and to epidemiological aspects.

• Biomolecules & Therapeutics
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• v.21 no.4
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• pp.290-298
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• 2013

This study examined the effects of calcium (Ca) gluconate on collagen-induced DBA mouse rheumatoid arthritis (CIA). A single daily dose of 200, 100 or 50 mg/kg Ca gluconate was administered orally to male DBA/1J mice for 40 days after initial collagen immunization. To ascertain the effects administering the collagen booster, CIA-related features (including body weight, poly-arthritis, knee and paw thickness, and paw weight increase) were measured from histopathological changes in the spleen, left popliteal lymph node, third digit and the knee joint regions. CIA-related bone and cartilage damage improved significantly in the Ca gluconate-administered CIA mice. Additionally, myeloperoxidase (MPO) levels in the paw were reduced in Ca gluconate-treated CIA mice compared to CIA control groups. The level of malondialdehyde (MDA), an indicator of oxidative stress, decreased in a dose-dependent manner in the Ca gluconate group. Finally, the production of IL-6 and TNF-${\alpha}$, involved in rheumatoid arthritis pathogenesis, were suppressed by treatment with Ca gluconate. Taken together, these results suggest that Ca gluconate is a promising candidate anti-rheumatoid arthritis agent, exerting anti-inflammatory, anti-oxidative and immunomodulatory effects in CIA mice.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.9B
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• pp.857-866
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• 2009

Recently, IP mobility study of infra's common elements is undergoing processes to achieve FMC based on All-IP. Existing typical mobility technology based on IP is IETF's Mobile IP. However, it faced to limitations due to packet loss, delays when MN is moving on Mobile IP, also existing network infra - routers (FA)-needed to add/change the functions to support Mobile IP. In this paper, existing mobility problems based on IP and the suggested improvements for platforms which support mobility, quality, security are proposed. It discusses the performance on the current existing IP infrastructure derived from simulation analysis on mobility packet loss and delay. From the resulting data, improvements will also be outlined for optimal performance.

• Korean Journal of Veterinary Service
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• v.37 no.4
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• pp.253-261
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• 2014

Porcine circovirus disease (PCVD) is a major problem of swine industry worldwide, and diagnosis of PCV2, causal agent of PCVD, has been doing in clinical laboratories of pig disease by polymerase chain reaction (PCR) methods. But the PCR analyses have a serious problem of misdiagnosis by contamination of DNA, in particular, from carryover contamination with previously amplified DNA or extracted DNA from field samples. In this study, an uracil DNA glycosylase (UNG)-based direct PCR (udPCR) without DNA extraction process and DNA carryover contamination was developed and evaluated on PCV2 culture and field pig samples. The sensitivity of the udPCR combined with dPCR and uPCR was same or better than that of the commercial PCR (cPCR) kit (Median diagnostics, Korea) on PCV2-positive serum, lymph node and lung samples of the pigs. In addition, the udPCR method confirmed to have a preventing ability of mis-amplification by contamination of pre-amplified PCV2 DNA from previous udPCR. In clinical application, 170 pig samples (86 tissues and 84 serum) were analysed by cPCR kit and resulted in 37% (63/170) of positive reaction, while the udPCR was able to detect the PCV2 DNA in 45.3% (77/170) with higher sensitivity than cPCR. In conclusion, the udPCR developed in the study is a time, labor and cost saving method for the detection of PCV2 and providing a preventing effect for DNA carryover contamination that can occurred in PCR process. Therefore, the udPCR assay could be an useful alternative method for the diagnosis of PCV2 in the swine disease diagnostic laboratories.

• Convergence Security Journal
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• v.8 no.2
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• pp.41-50
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• 2008

Recently amount of traffic into the network rapidly increase since multimedia streaming services is generally adopted for application. In addition, various network management systems have been suggested for providing a stable service and QoS guarantee. It is necessary for such systems to have QoS monitoring module in order to evaluate acceptance or violation of QoS requirements by analogizing a state information of each node within network. In this paper, we suggest a network management system to evaluate QoS level between end-to-end agents and analysis traffics transmitted between them. The proposed system is implemented for the purpose of collecting network traffic information and monitoring of the view. The proposed system makes user easily understand information of QoS parameters such as throughput, delay and jitter by adopting a method of visual and numerical representation. To achieve this, we purportedly generate test packet into network for confirming acceptance or violation of QoS requirements from point of view of multimedia application service.

• Korean Journal of Agricultural Science
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• v.29 no.1
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• pp.8-14
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• 2002

Spray of maleic hydrazide (MH) was confirmed to be highly effective on the inhibition of lateral shoot growth regardless of grape cultivars and application concentration examined in this experiment. The optimal spray times were 30 days aft er full bloom in 'Kyoho' and 35 days in 'Campbell Early'. However, the optimum season of application should be adjusted depending on the vine vigor. The apical buds of lateral shoot was significantly affected at the concentration of $3,900mg{\cdot}L^{-1}$ resulting in the death and/or abscission. Thus the optimal concentration of MH seemed to be $1,950mg{\cdot}L^{-1}$. The inhibition effect by MH application was derive d from the decrease of node number and length. No adverse effect on fruit quality was found by MH application. In contrast, there was a tendency of anthocyanin in crease in 'Campbell Early' grapes. Results indicated that MH could be an effective agent to reduce the labor charge through the inhibition of later shoot growth.

• Journal of KIISE:Information Networking
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• v.30 no.5
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• pp.595-603
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• 2003

To provide mobile nodes with continuous communication services, it is important to reduce the packet losses during handoffs. The handoffs of mobile nodes cause packet losses and decrease of TCP throughput on account of a variety of factors. One of those is the congestion in the new cell. Due to the congestion, not only the node moving into the cell but also the already existing nodes that were successfully communicating in the cell suffer the performance degradation. In this paper we propose a new handoff mechanism called‘packet freeze control’, which avoids the congestion caused by handoffs by regulating the influx of traffic burst into the new cell. Packet freeze control is applicable to a wireless network domain in which FAs(Foreign Agents) are connected hierarchically and constitute a logical tree. It gradually increases the number of packets transferred to the new cell by buffering packets in the FAs on the packet delivery path over the wireless network domain. The simulation results show that the proposed mechanism not only reduces the packet losses but also enhances the TCP throughput of other mobile nodes in the cell.