• Title/Summary/Keyword: after migration

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Aquaporin 8 Involvement in Human Cervical Cancer SiHa Migration via the EGFR-Erk1/2 Pathway

  • Shi, Yong-Hua;Tuokan, Talaf;Lin, Chen;Chang, Heng
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.15
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    • pp.6391-6395
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    • 2014
  • Overexpression of aquaporins (AQPs) has been reported in several human cancers. Epidermal growth factor receptor (EGFR)-extracellular signal-regulated kinases 1/2 (Erk1/2) are associated with tumorigenesis and cancer progression and may upregulate AQP expression. In this study, we demonstrated that EGF (epidermal growth factor) induces SiHa cells migration and AQP8 expression. Wound healing results showed that cell migration was increased by 2.79-1.50-fold at 24h and 48h after EGF treatment. AQP8 expression was significantly increased (3.33-fold) at 48h after EGF treatment in SiHa cells. An EGFR kinase inhibitor, PD153035, blocked EGF-induced AQP8 expression and cell migration and AQP8 expression was decreased from 1.59-fold (EGF-treated) to 0.43-fold (PD153035-treated) in SiHa. Furthermore, the MEK (MAPK (mitogen-activated protein kinase)/Erk (extracellular signal regulated kinase)/Erk inhibitor U0126 also inhibited EGF-induced AQP8 expression and cell migration. AQP8 expression was decreased from 1.21-fold (EGF-treated) to 0.43-fold (U0126-treated). Immunofluorescence microscopy further confirmed the results. Collectively, our findings show that EGF induces AQP8 expression and cell migration in human cervical cancer SiHa cells via the EGFR/Erk1/2 signal transduction pathway.

The Analysis of Retention Characteristic according to Remnant Polarization(Pr) and Saturated Polarization(Ps) in 3D NAND Flash Memory (3D NAND Flash Memory의 Remnant Polarization(Pr)과 Saturated Polarization(Ps)에 따른 Retention 특성 분석)

  • Lee, Jaewoo;Kang, Myounggon
    • Journal of IKEEE
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    • v.26 no.2
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    • pp.329-332
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    • 2022
  • In this paper, retention characteristics of lateral charge migration according to parameters of 3D NAND flash memory to which ferroelectric (HfO2) structure is applied and ∆Vth were analyzed. The larger the Ps, the greater maximum polarization possible in ferroelectric during Programming. Therefore, the initial Vth increases by about 1.04V difference at Ps 70µC/cm2 than at Ps 25µC/cm2. Also, electrons trapped after the Program operation causes lateral charge migration over time. Since ferroelectric maintains polarization without applying voltage to the gate after Programming, regardless of Ps value, polarization increases as Pr increases and the ∆Vth due to lateral charge migration becomes smaller by about 1.54V difference at Pr 50µC/cm2 than Pr 5µC/cm2.

A Study on the Place Name of Migration in Three Northeast Provinces of China I : Case of the Yanbian Korean Autonomous Prefecture (중국 동북 3성의 이식지명에 관한 연구 I - 연변 조선족 자치주를 사례로 -)

  • Kim, Nam-Sin;Jin, Shizhu
    • Journal of the Korean association of regional geographers
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    • v.20 no.2
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    • pp.153-162
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    • 2014
  • This Research is to study types and distribution for place name of migration derived from Korea Peninsula by analyzing villages name of the Yanbian Korean Autonomous Prefecture. Village names of Yanbian Korean were identified as 945 out of 2,015. Place name migrated from Korea Peninsula was turned out 51 villages. Up to the present time in the Transition of China, 34 place names were disappeared, maintained place names were 16, and rehabilitated place name after loss was 1. The place name by naming method were classified as small area directed migration, large area directed migration, and merged migration. In case of small area directed migration, origin and destination is same such as Jeongeup and Muju, Cheonbuk, large area directed migration is named case by region migrants like a Gangwonchon named by people moved from GanwonDo, and merged case combine initials with each village names in case of GilseongChon by colligated Gilju and Seokseongmyeon. The results will be expected to support research information for identity and ethnical migration process.

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Migration of THO & Np in a Fractured Granite Core at Deep Underground Laboratory

  • PARK Chung-Kyun;CHO Won-Zin;HAHN Pil-Soo;KIENZLER B.
    • Proceedings of the Korean Radioactive Waste Society Conference
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    • 2005.06a
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    • pp.255-263
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    • 2005
  • Migration experiments of THO and 237Np have performed through a sampled granite core in Chemlab2 probe at the Aspo hard Rock laboratory. The elution curves of THO were analysed to determine hydraulic properties such as the extent of dispersion effect according to flow rates. The retardation phenomena of the solutes were observed and described with elution curves and migration plumes. After migration test, the rock core was opened, and the remaining radioactivities on the rock fracture surfaces were measured. The transport process was simulated with a two-dimensional channel model. The mass transport process was described with three types of basic processes ; advection, sorption and matrix diffusion. By the combination of these processes, effects of each process on transport were described in terms of elution curves and migration plumes. By comparing the simulation results to the experimental one, it was possible to analyse the retardation effect quantitatively.

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Enhancement of VECTOR Method by Adapting OCTAVE for Risk Analysis in Legacy System Migration

  • Hakemi, Aida;Jeong, Seung Ryul;Ghani, Imran;Sanaei, Mojtaba Ghanaatpisheh
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.8 no.6
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    • pp.2118-2138
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    • 2014
  • Risks are involved in all phases of the software life cycle, and due to these risks, software can face various problems that can cause different negative outcomes and sometimes, in extreme cases, the failure of the software. Most of these risks lie in the legacy software migration process. These risks can create many problems, and in the worst case they can lead to the failure of the migration project. This paper explores different types of risk analysis methods such as CRAMM, CORAS, OCTAVE and VECTOR. After comparing these methods, the two suitable methods were chosen, namely, OCTAVE and VECTOR. Based on the use of these two methods, the project suggests an enhanced EOV method for risk analysis in the migration of legacy software.

Upward Migration of a Peritoneal Catheter Following Ventriculoperitoneal Shunt

  • Cho, Kyung Rae;Yeon, Je Young;Shin, Hyung Jin
    • Journal of Korean Neurosurgical Society
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    • v.53 no.6
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    • pp.383-385
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    • 2013
  • We present an unusual case of peritoneal catheter migration following a ventriculoperitoneal shunt operation. A 7-month-old infant, who had suffered from intraventricular hemorrhage at birth, was shunted for progressive hydrocephalus. The peritoneal catheter, connected to an 'ultra small, low pressure valve system' (Strata$^{(R)}$; PS Medical,Gola, CA, USA) at the subgaleal space, was placed into the peritoneal cavity about 30 cm in length. The patient returned to our hospital due to scalp swelling 21 days after the surgery. Simple X-ray images revealed total upward migration and coiling of the peritoneal catheter around the valve. Possible mechanisms leading to proximal upward migration of a peritoneal catheter are discussed.

The Environmental Justice in Ecological Immigration A Case Study of Sanjiangyuan Area

  • Ma, Shuang;Ma, Sa
    • Architectural research
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    • v.17 no.4
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    • pp.147-152
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    • 2015
  • Recently, there is an increasing criticism both inside and outside China toward the eco-migration projects. The author focuses on the eco-migration of Sanjiangyuan National Nature Reserve as a case study as it is one of the main eco-migration projects. At the end of 2010, government invested 4.47 billion CNY in eco-migration and relocated the immigration 55773 people in 10733 units. Benefits of eco-migration is obvious, however, it needs to be recognized that in the aspect of environment justice, it is unfair to sacrifice a group of people in the process of environmental protection because costs and benefits result from the environmental protection have to share among the people without discrimination. Local herdsmen received extra disadvantages in their level of material possessions, social and cultural values and the social inclusion after eco-migration project. As a part of the eco-social system established within several centuries, the local herdsmen are not only threateners to local ecology system, but also the guardians to the natural environment through religion and habits last for generations. The social and cultural values, traditional religion and Nomadic living habits, as important as the environment, are need to be cherished and protected.

Inhibitory Effects on Human Breast Cancer Cells Migration of Small Black Bean according to the Cooking Methods (조리방법을 달리한 쥐눈이콩의 인체유방암세포 이동성 억제 효과)

  • Shin, Jihun;Joo, Nami
    • The Korean Journal of Food And Nutrition
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    • v.30 no.4
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    • pp.728-734
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    • 2017
  • After being subjected to different cooking methods, small black beans (Rhynchosia nulubilis) were investigated in order to assess the effects of the retained bioactive compounds. Using uncooked, pan broiled, boiled, steamed, and pressure cooked beans, the inhibitory effects of MCF-7 cell migration were evaluated at protein concentrations of 40, 160, and $640{\mu}m/mL$, using the Boyden's chamber assay. All protein concentrations (40, 160, and $640{\mu}m/mL$) of pan broiled beans showed significant reduction (59.83, 32.48, and 21.37%, respectively) in the rate of cell migration to the lower chambers (p-value less than 0.001). Estimated cell migration rates correlated to the exponential decay between experimentally measured cell migration rates and converted samples. The range of estimated cell migration rate for each 100 mg/mL of cooked sample was as follows: pan broiled (21.16%), boiled (22.48%), steamed (22.48%), pressure cooked (29.52%), and uncooked (35.03%) beans. Our study indicated that selective modifications of cooking methods for small black beans, such as pan broiling, ameliorated the inhibitory effects of MCF-7 cell migration. This suggests that optimized cooking methods increase the nutritional contents of the cooked food.

The Effect of Thoracic Joint Mobilization on the Changes of the Thoracic Kyphosis Angle and Static and Dynamic Balance

  • Jeong, Hae-Jin;Kim, Byeong-Jo
    • Biomedical Science Letters
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    • v.25 no.2
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    • pp.149-158
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    • 2019
  • The objective of this study was to evaluate the effects of thoracic mobilization (TM) on the angle of thoracic kyphosis, and static and dynamic balances by application period. The subjects of this study were 18 adult males and females (${\geq}20years\; old$) who had the angle of thoracic kyphosis equal to or higher than $40^{\circ}$. A pre-test was conducted for all subjects and TM was carried out. Data were collected before the intervention, 3 weeks after the intervention, and 6 weeks after the intervention. It was measured three times per measurement and mean values were used for the analysis. The results of this study showed that the angle of thoracic kyphosis significantly (P<.05) decreased after applying TM. However, the migration area ($mm^2$) of the center of pressure (COP) in the static balance did not vary significantly. In the case of the dynamic balance, when eyes were open, the migration area ($mm^2$) of the COP significantly (P<.05) decreased after 3 weeks. When eyes were open, the migration area ($mm^2$) of the COP significantly (P<.05) decreased after 3 weeks and 6 weeks. Therefore, an intervention for improving the human body alignment and balance should be applied for a long-term, rather than a short-term, in order to be effective.

Study on the Migration of Fluorescent Whitening Agents Used for Papermaking Process (제지용 형광증백제의 전이현상에 대한 기초연구)

  • Lee, Ji Young;Kim, Chul Hwan;Sung, Yong Joo;Kim, Eun Hea;Kim, Jae Hyung;Park, Tae Ung
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.48 no.3
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    • pp.5-13
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    • 2016
  • This study investigated the effects of different factors on the migration of a fluorescent whitening agent (FWA) from paper treated with FWAs to non-fluorescent papers. FWA migration experiments were carried out in vertical and friction contacts between the papers dyed with FWAs and non-fluorescent papers. During the experiments, we identified the effects of the addition and types of FWAs, contact time, temperature, and relative humidity (RH) on FWA migration. The fluorescence indices of the non-fluorescent papers were measured before and after the migration experiments, and the Student's t test, a statistical tool, was utilized to compare results from different migration experiments. In vertical contact experiments, FWA migration to non-fluorescent paper was observed at $30^{\circ}C$ and 70% RH; this was attributed to the high moisture content of the paper. FWA migration did not occur significantly at $23^{\circ}C$ and 50% RH. In the friction contact experiments, FWA migrations were identified at both temperature conditions and RH percentages. The addition and types of FWAs did not increase the fluorescence index of non-fluorescent papers. Therefore, it was concluded that the moisture content of paper and the friction contact affected FWA migration from the papers containing internal and surface FWAs.