• The Korean Journal of Community Living Science
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• v.25 no.3
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• pp.321-338
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• 2014

This study was examined the level of satisfaction in rural settlement and analyzed its differences according to various demographic variables and characteristics of urban-rural migration. The analysis was conducted by considering returning farmers residing in rural areas. A statistical analysis was conducted using t-test, one-way ANOVA, and Duncan's multiple-range test with a total of 210 responses. First, satisfaction with the convenience of living facilities varied significantly according to the occupation before urban-rural migration, responses of family members and friends to urban-rural migration, and the initial capital for urban-rural migration. Second, satisfaction with the natural environment varied significantly according to age and reasons for urban-rural migration. Third, satisfaction with the transportation environment varied significantly according to gender, the period of residence after urban-rural migration, and the employment type of the returning farmer. Fourth, satisfaction with neighborliness varied significantly according to parents' occupation, agricultural experience before urban-rural migration, experience in agriculture-related social life before urban-rural migration, reasons for urban-rural migration, the type of urban-rural migration, and the employment type of the returning farmer. Fifth, satisfaction with the agricultural environment varied significantly according to responses of family members and friends to urban-rural migration, the period of residence after urban-rural migration, and reasons for urban-rural migration. Sixth, satisfaction with the housing environment varied significantly according to the residential area, the agricultural experience before urban-rural migration, and the period of residence after urban-rural migration.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.7 no.6
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• pp.1398-1417
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• 2013

A method is proposed to reduce excess resources from a virtual machine(VM) while avoiding subsequent migrations for a computer cluster that provides cloud service. The proposed scheme cuts down on the resources of a VM based on the probability that migration may occur after a reduction. First, it finds a VM that can be scaled down by analyzing the history of the resource usage. Then, the migration probability is calculated as a function of the VM resource usage trend and the trend error. Finally, the amount of resources needed to eliminate from an underutilized VM is determined such that the migration probability after the resource reduction is less than or equal to an acceptable migration probability. The acceptable migration probability, to be set by the cloud service provider, is a criterion to assign a weight to the resource reduction either to prevent VM migrations or to enhance VM utilization. The results of simulation show that the proposed scheme lowers migration frequency by 31.6~60.8% depending on the consistency of resource demand while losing VM utilization by 9.1~21.5% compared to other known approaches, such as the static and the prediction-based methods. It is also verified that the proposed scheme extends the elapsed time before the first occurrence of migration after resource reduction 1.1~2.3-fold. In addition, changes in migration frequency and VM utilization are analyzed with varying acceptable migration probabilities and the consistency of resource demand patterns. It is expected that the analysis results can help service providers choose a right value of the acceptable migration probability under various environments having different migration costs and operational costs.

• Journal of Korean Neurosurgical Society
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• v.47 no.3
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• pp.221-223
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• 2010

C1 lateral mass and C2 pedicle (C1LM-C2P) fixation is a relatively new technique for atlantoaxial stabilization. Complications from C1LM-C2P fixation have been rarely reported. The authors report unilateral rod migration into the posterior fossa as a rare complication after this posterior C1-C2 stabilization technique. A 23-year-old man suffered severe head trauma and cervical spine injury after vehicle accident. He was unconscious for 2 months and regained consciousness. He underwent C1LM-C2P fixation for stabilization of type II odontoid process fracture described by Harms. The patient recovered without a major complication. Twenty months after operation, brain computed tomogram performed at psychology department for disability evaluation showed rod migration into the right cerebellar hemisphere. The patient had mild occipital headache and dizziness only regarding the misplaced rod. He refused further operation for rod removal. To our knowledge, this complication is the first report regarding rod migration after Harms method. We should be kept in mind the possibility of rod migration, and C1LM-C2P fixation should be performed with meticulous technique and long-term follow-up.

• BMB Reports
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• v.55 no.5
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• pp.244-249
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• 2022

Characterized by abnormal proliferation and migration of vascular smooth muscle cells (VSMCs), neointima hyperplasia is a hallmark of vascular restenosis after percutaneous vascular interventions. Vaccinia-related kinase 1 (VRK1) is a stress adaption-associated ser/thr protein kinase that can induce the proliferation of various types of cells. However, the role of VRK1 in the proliferation and migration of VSMCs and neointima hyperplasia after vascular injury remains unknown. We observed increased expression of VRK1 in VSMCs subjected to platelet-derived growth factor (PDGF)-BB by western blotting. Silencing VRK1 by shVrk1 reduced the number of Ki-67-positive VSMCs and attenuated the migration of VSMCs. Mechanistically, we found that relative expression levels of β-catenin and effectors of mTOR complex 1 (mTORC1) such as phospho (p)-mammalian target of rapamycin (mTOR), p-S6, and p-4EBP1 were decreased after silencing VRK1. Restoration of β-catenin expression by SKL2001 and re-activation of mTORC1 by Tuberous sclerosis 1 siRNA (siTsc1) both abolished shVrk1-mediated inhibitory effect on VSMC proliferation and migration. siTsc1 also rescued the reduced expression of β-catenin caused by VRK1 inhibition. Furthermore, mTORC1 re-activation failed to recover the attenuated proliferation and migration of VSMC resulting from shVrk1 after silencing β-catenin. We also found that the vascular expression of VRK1 was increased after injury. VRK1 inactivation in vivo inhibited vascular injury-induced neointima hyperplasia in a β-catenin-dependent manner. These results demonstrate that inhibition of VRK1 can suppress the proliferation and migration of VSMC and neointima hyperplasia after vascular injury via mTORC1/β-catenin pathway.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.5
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• pp.305-314
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• 2020

The paper explores the return migration choice of graduates, which takes place during the transition from higher education to the labor market. Graduate students, after a short time in temporary migration to cities for studying, have to make a decision of returning back home or staying in migration in urban areas for working. Drawing on the mechanism identified in the literature on internal migration, this empirical research tests the effects of two factors: place attractiveness and social supports factors on graduates' decision to return migration to hometown. A binary logit regression analysis was conducted with data from 502 surveyed graduates in Hanoi, Vietnam. The analysis of the motives reported by graduates indicates that return migration decisions cannot be reduced to a single dimension. Perceived attractiveness of a region such as quality of living environment, job opportunities, and social context of individuals positively impact on student' decision to return migration after graduation. The research results imply that, in a collectivistic country like Vietnam, students' choice of future career is strongly influenced by their social context, and choosing a place to work is not simply a matter of earning a higher salary or enjoying better working conditions, but is also related to family issues.

• Biomolecules & Therapeutics
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• v.20 no.2
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• pp.165-170
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• 2012

Cell migration plays a role in many physiological and pathological processes. Reactive oxygen species (ROS) produced in mammalian cells influence intracellular signaling processes which in turn regulate various biological activities. Here, we investigated whether melanoma cell migration could be controlled by ROS production under normoxia condition. Cell migration was measured by wound healing assay after scratching confluent monolayer of B16F10 mouse melanoma cells. Cell migration was enhanced over 12 h after scratching cells. In addition, we found that ROS production was increased by scratching cells. ERK phosphorylation was also increased by scratching cells but it was decreased by the treatment with ROS scavengers, N-acetylcysteine (NAC). Tumor cell migration was inhibited by the treatment with PD98059, ERK inhibitor, NAC or DPI, well-known ROS scavengers. Tumor cell growth as judged by succinate dehydrogenase activity was inhibited by NAC treatment. When mice were intraperitoneally administered with NAC, the intracellular ROS production was reduced in peripheral blood mononuclear cells. In addition, B16F10 tumor growth was significantly inhibited by in vivo treatment with NAC. Collectively, these findings suggest that tumor cell migration and growth could be controlled by ROS production and its downstream signaling pathways, in vitro and in vivo.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.02a
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• pp.526-526
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• 2013

Plasma technology isbeing developed for a range of medical applications including wound healing. However, the effect of plasma on many cells and tissues is unclear. Cell migration and cell proliferation are very important biological processes which are affected by plasma exposure and might be a potential target for plasma therapy during wound healing treatment. In this study, we confirmed the plasma exposure time and incubation time after plasma treatment in skin fibroblast (L-929 cells) to evaluate the optimal conditions forplasma exposure to the cell in-vitro. In addition, we used a scratch method to generate artificial wound for evaluating the cell migration by plasma treatment. Where, the cells were treated with plasma and migration rate was observed by live-cell imaging device. To find the cell proliferation, cell viability assay was executed. The results of this study indicate the increased cell proliferation and migration on mild plasma treatment. The mechanisms for cell migration and cell proliferation after plasma treatment for future studies will be discussed.

• Korean System Dynamics Review
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• v.11 no.4
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• pp.117-142
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• 2010

National territorial policies require a series of dynamic simulations, which would facilitate effectiveness measuring and forecasting works geared towards territorial policies under consideration or implementation. This paper aims at designing an integrated prototype for the proposed territorial policies. After the simulation exercises for the Ochang Industrial Complex(OIC) in Chungbuk Province, this study firstly finds meaningful mismatch phenomena between housing and population increases as the in-migration time lag seems inevitable even after the housing construction is in a mature state. Secondly, the OIC development exerts more significant impact on the number of employees than that of business units. Thirdly, in- and out-migration orders are different during the first and second stages of OIC development. That is, Chungbuk Province records the largest in terms of in-migration volume, followed by the Capital and Non-Capital Regions. Even though Chungbuk Province ranks the top position in the out-migration volume, the rank of the Capital and Non-Capital Regions is reversed: the our-migration volume towards the Non-Capital Region outruns that of the Capital Region.

• Journal of Veterinary Clinics
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• v.38 no.6
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• pp.261-268
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• 2021

The study was conducted to evaluate the effects of carboxymethyl chitosan (CMC) on proliferation, migration, and lipopolysaccharide (LPS)-induced inflammatory response in canine bone marrow-derived mesenchymal stem cells (BMSCs). The proliferation and migration of BMSCs were examined after treatment with CMC. The effect of CMC on the mRNA expression of inflammatory cytokines, such as interleukin (IL)-1β, IL-6, tumor necrosis factor (TNF)-α, IL-10, and transforming growth factor (TGF)-β, was also evaluated by reverse transcription polymerase chain reaction (RT-PCR). In the proliferation assay, no significant changes were found at all CMC concentrations compared with controls. The migration assay showed that CMC dose-dependently stimulated the migration of BMSCs in normal and LPS-treated conditions. RT-PCR showed that TNF-α and IL-10 expressions were suppressed in the BMSCs after CMC treatment. However, other genes were not affected. Taken together, CMC promoted BMSC migration and inhibited TNF-α and IL-10. Therefore, CMC may be possible to regulate wound healing when mesenchymal stem cells are applied in inflammatory diseases.

• Clinics in Shoulder and Elbow
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• v.17 no.2
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• pp.77-79
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• 2014

The migration of metallic devices such as Kirschner's wire (K-wire) from the shoulder is a well-recognized and significant complication of operation, the wire ending up in the lungs, the heart, the esophagus, the aorta or the subclavian artery. However, spinal migration is very rare. We report the case of a 72-year-old female patient with K-wire migration into the C7-T1 intervertebral foramen, 2 months after surgery for a lateral end fracture of left clavicle.