• 대한통합의학회지
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• 제6권1호
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• pp.55-62
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• 2018

Purpose : Preeclampsia(PE) is a pregnancy-specific disease which is characterized by hypertension and proteinuria. This disease occurs in about 2-8 % of pregnancies in developing countries and remains among the major causes of maternal and neonatal mortality and morbidity throughout the world. Although the causes of PE are not fully understood, the infection has been considered as the main risk factor for this diseases. Periodontal disease may provide a chronic burden of endotoxin and inflammatory cytokines and the disease has been considered as risk factors of systemic illnesses including cardiovascular disease, atherosclerosis, and cerebrovascular ischemia. So, studies performed over the last 15 years have suggested that periodontal disease may be associated with adverse pregnancy outcomes such as PE. However, this association has not been found in all populations. The aim of this review article was to evaluate whether periodontal status and the presence of specific periodontal pathogens may influence the incidence of PE. Methods : Many research articles searched at the electronic databases(MEDLINE; 2000 to July 2017) including search term as periodontal disease and preeclampsia. Result : There were 10 case-control studies and 5 cohort studies meeting our inclusion criteria. The results showed that maternal periodontitis (adjusted odds ratio: 1.5 to 9.3) was associated with preeclampsia in 15 epidemiological studies. Conclusion : It is clear that maternal periodontitis is a risk factor associated with preeclampsia, emphasizing the importance of periodontal care in prenatal programs.

• Ocean Systems Engineering
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• 제5권4호
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• pp.261-277
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• 2015

Internal solitary waves occur due to density stratification and are nonlinear in nature. These waves have been observed in many parts of the world including the South China Sea, Andaman Sea and Sulu Sea. Their effect on floating systems has been an emerging field of interest and recent offshore developments in the South China Sea where several offshore oil and gas discoveries are located have confirmed adverse effects including large platform motions and riser system damage. A valid numerical model conforming to the physics of internal waves is implemented in this paper and the effect on a spar platform is studied. The physics of internal waves is modeled by the Korteweg-de Vries (KdV) equation, which has a general solution involving Jacobian elliptical functions. The effects of vertical density stratification are captured by solving the Taylor Goldstein equation. Fully coupled time domain analyses are conducted to estimate the effect of internal waves on a typical truss spar, which is configured to South China Sea development requirements and environmental conditions. The hull, moorings and risers are considered as an integrated system and the platform global motions are analyzed. The study could be useful for future guidance and development of offshore systems in the South China Sea and other areas where the internal wave phenomenon is prominent.

• Asian-Australasian Journal of Animal Sciences
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• 제24권7호
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• pp.946-951
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• 2011

The study was conducted to evaluate enzose (corn dextrose), a corn milling byproduct, as substitute for corn grain as energy in growing lambs. Five iso-caloric and iso-nitrogenous diets were formulated. The control diet (E0) had no enzose whereas enzose replaced 20, 40, 60 and 80% corn grain in E20, E40, E60 and E80 diets on the basis of energy supply, respectively. Fifty growing lambs were divided into 5 groups, 10 animals in each, in a randomized complete block design. Nutrients (dry matter, crude protein, neutral detergent fiber and acid detergent fibre) intake and digestibilities increased with gradual replacement of corn grain by enzose. Lambs fed E80 diet also retained higher nitrogen (N) than those fed E0 diet. Plasma glucose, $T_3$ and $T_4$ increased while urea N decreased in lambs receiving higher enzose content. Maximum weight gain was recorded in lambs fed diets containing maximum concentration of E as a replacement for corn grains. A better feed conversion ratio was recorded in lambs fed E80 compared with those fed E0 diet. The study suggests that enzose can be used as an economical feed ingredient to replace corn grain upto 80%, without any adverse effects on growth performance of growing lambs.

• Molecular & Cellular Toxicology
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• 제4권3호
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• pp.230-234
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• 2008

Epidemiological studies demonstrate an adverse effect of several environmental and occupational exposures on male sex hormone. Bisphenol A (BPA) is a weak estrogen and a widely used industrial chemical. Epoxy resin painters may be continuously exposed to BPA at high concentrations. The effect of occupational exposure of BPA on male reproduction was examined by measuring the urinary BPA, testosterone and gonadotropic hormones of epoxy resin painters in the shipyard. The painters had significantly higher concentrations of urinary BPA (2.61${\pm}$1.08 ${\mu}g$/g creatinine) than controls (1.38${\pm}$0.5 9 ${\mu}g$/g creatinine). In serum, the testosterone level of painters was significantly decreased but the luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels of painters were significantly higher than controls. Occupational exposure to BPA influences testosterone and gonadotropic hormones in male workers.

• 한국연초학회지
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• 제13권2호
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• pp.66-70
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• 1991

A field experiment was conducted to study the effects of fertilizer application rate and number of harvested leaves per plant on selected agronomic, chemical and physical characteristics of burley tobacco(Nicotiana tabacum L. cv Burley 21) in 1988, 1989 and 1990 at Chonju Experiment Station, Korea Ginseng SE Tobacco Research Institute. 175.0 or 227.5 kilogram per 10a of compound fertilizer(N-P2O5-K2O= 10-10-20) were applied as main plot, and 2 or 4 of upper leaves was topped off with 0, 2 or 4 of the lower leaves removed as sub plot. Yield, total alkaloid and total nitrogen content of cured leaves were high in the higher level of compound fertilizer plot, and increasing the level of compound fertilizer had an adverse effect on physical characteristics. Reducing the number of harvested leaves had a negative effect on yield regardless of whether the leaf number was reduced by lower topping or removing the bottom leaves, but increased the rate of higher grades leaves. Differences in total alkaloid, total nitrogen and some physical properties among number of harvested leaf per plant were smaller than expected.

• 한국임상수의학회지
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• 제16권1호
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• pp.42-49
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• 1999

The reproductive effect of $Telazol^{\circledR}$ was studied in pregnant rats. Two different doses (20 or 40 mg/kg/day) were injected on days one of 3, 5 or 8 of pregnancy and 3 consecutive days of 3~5 or 5~7 in pregnant rats. On days 8 or 21, the rats were anesthetized, the cesarean section was performed, the uterus was carefully examined, and the numbers of corpora lutea, implantation sites and viable fetuses, fetal and placental weights and pre-and post-implantation losses in rats were surveyed. Simultaneously the concentrations of sodium and potassium of the plasma, uterine and amniotic fluids were determined. And gestation period in pregnant rats, postnatal offspring survival and body weight gains were evaluated. Administration of $Telazol^{\circledR}$ did not exert a bad influence upon body weight gains in pregnant rats. Reproductive indices were normal. The concentrations of sodium and potassium of the plasma, uterine and amniotic fluids in pregnant rats remained unchanged. Gestation period of rats, postnatal offspring survival and body weight gains were normal. It is concluded that $Telazol^{\circledR}$ is devoided of significant adverse reproductive effects in pregnant rats.

• 융복합기술연구소 논문집
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• 제5권2호
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• pp.27-32
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• 2015

Air intakes are an essential component of aircraft engines. They are mainly used to offer uniform airflows to engine faces. Fighter aircraft have to mask the engine face inside the fuselage in order to reduce the Radar Cross Section(RCS). Therefore, offset intakes like a S-Duct are one of promising components for this purpose. During a fight, it is unavoidable that the flow will enter the intakes at some face angles other than zero. In this case, the performance of the aircraft engine will be influenced to the angle of incidence. In this study, the CFD analysis of the semi-circular S-Duct with AR(0.5,0) is performed to investigate the influence of the angle of incidence on the performance of the S-Duct using a distortion coefficient. To consider the adverse pressure gradient, a $k-{\omega}$ SST turbulence model is employed. The secondary flow and flow separation are observed for all computational cases. It is found that the positive incidence angle produces the best performances.

• Journal of Microbiology and Biotechnology
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• 제27권1호
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• pp.84-91
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• 2017

The concern over the use of melittin in honey bee venom due to its adverse reaction caused by allergens such as phospholipase A2 ($PLA_2$) and hyaluronidase (HYA) has been an obstacle towards its usage. We developed a novel single-step method for melittin purification and the removal of $PLA_2$ and HYA. This study explores the influence of pH, buffer compositions, salt concentration, and types of cation-exchange chromatography resins on the recovery of melittin and the removal of both HYA and $PLA_2$. Melittin was readily purified with a strong cation-exchange resin at pH 6.0 with sodium phosphate buffer. It resulted in a recovery yield of melittin up to 93% (5.87 mg from a total of 6.32 mg of initial melittin in crude bee venom), which is higher than any previously reported studies on melittin purification. $PLA_2$ (99%) and HYA (96%) were also successfully removed. Our study generates a single-step purification method for melittin with a high removal rate of $PLA_2$ and HYA, enabling melittin to be fully utilized for its therapeutic purposes.

• 한국생활과학회지
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• 제22권6호
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• pp.587-598
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• 2013

This study is to examine (the) effects of self-control, parent-adolescent communication, and school life satisfaction on smart-phone addiction for middle school students. The 127 students who were classified as smart-phone addicts among first to third grade at two middle schools located in Gyunggido were sampled with a survey. T-tests, ANOVA, Pearson's correlation, and multiple regression analysis were used. The results of study were as follows. First, smart-phone addiction make no difference according to adolescent's sex and grade. Second, the relations between smart-phone addiction and the factors included self-control, parent-adolescent communication, and school life satisfaction were negatively correlated. As a result, the higher self-control, parent-adolescent communication, and school life satisfaction were, the lower smart -phone addiction was. Third, it is significant as variable that adverse effect, low rank class of parent-adolescent communication and personal relationship, same class as the former of school life satisfaction exert influence on smart phone addiction.

• Geomechanics and Engineering
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• 제15권6호
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• pp.1193-1205
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• 2018

A footing located on slopes possess relatively lower bearing capacity as compared to the footing located on the level ground. The bearing capacity further reduces under seismic loading. The adverse effect of slope inclination and seismic loading on bearing capacity can be minimized by proving sufficient setback distance. Though few earlier studies considered setback distance in their analysis, the range of considered setback distance was very narrow. No study has explored the critical setback distance. An attempt has been made in the present study to comprehensively investigate the effect of setback distance on footing under seismic loading conditions. The pseudo-static method has been incorporated to study the influence of seismic loading. The rate of decrease in seismic bearing capacity with slope inclination become more evident with the increase in embedment depth of footing and angle of shearing resistance of soil. The increase in bearing capacity with setback distance relative to level ground reduces with slope inclination, soil density, embedment depth of footing and seismic acceleration. The critical value of setback distance is found to increase with slope inclination, embedment depth of footing and density of soil. The critical setback distance in seismic case is found to be more than those observed in the static case. The failure mechanisms of footing under seismic loading is presented in detail. The statistical analysis was also performed to develop three equations to predict the critical setback distance, seismic bearing capacity factor ($N_{{\gamma}qs}$) and change in seismic bearing capacity (BCR) with slope geometry, footing depth and seismic loading.