• 제목/요약/키워드: additive effects

검색결과 1,311건 처리시간 0.04초

Aloe vera가 항암제의 세포독성에 미치는 영향 (Effects of Aloe vera on the Cytotoxicity of Anticancer Drugs in Vitro)

  • 표명윤;윤지현
    • 약학회지
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    • 제43권1호
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    • pp.104-110
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    • 1999
  • We investigated effects of methanol extract of Aloe vera on anticancer drugs(cisplatin, mitomycin C, 5-fluorouracil)-induced growth inhibition in p388, L1210, HCT-15, SK-HepG-1 as cancer cell lines and mouse splenocytes as a normal cell by MTT assay, respectively. We also examined the effects of aloe extract and mitomycin C on the mitogen(Con, A, LPS)-induced splenocyte proliferation. Aloe extract(0.25 mg/m , 1.25 mg/m , 2.5 mg/m , 5.0 mg/m ) showed dose-dependently selective cytotoxicity against the cancer cell lines. In contrast, Aloe extract increased the growth and proliferation of the normal mouse splenocytes. The combination of aloe extract with anticancer drugs showed an additive effect for the cytotoxicity against cancer cell lines. However, that combination reduced clealy the anticancer drugs-induced toxicity against the normal mouse splenocytes.

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무전해 동 도금용액 속에서 안정제의 역할 (Effects of Stabilizing Additives on Electroless Copper Deposition)

  • 최순돈;박범동
    • 한국표면공학회지
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    • 제25권4호
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    • pp.173-180
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    • 1992
  • The effects of the stabilizing additives such as NaCN, 2-MBT and Thiourea on bath decom-position, plating rate and surface morphology have been studied. Bath stability was increased in the order of an additive-free bath, and NaCN-, 2-MBT-, and Thiourea-stabilized baths. The sta-bilizing effects may be attributed to the stability of Cu(II) -complexes. The plating rate is the re-verse order of the bath stability. Accelerative effect of 2-MBT in proper quantity(0.3mg/$\ell$) may be explained by visualizing it absorbed through benzene ring or sulfur atom on portions of the sub-strates. The strong bond of the complexing part of the molecule to nearby chelated copper ions would tend to accelerate plating by making it easier for the Cu2+ -ligand bond to be broken. Sur-face morphologies of copper deposits depend on the bath additives. Electroless copper deposits from the 2-MBT stabilized baths are finer than the deposits from the NaCN- and Thiourea- stabi-lized baths due to the strong adsorption on the substrates.

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송지의 세포독성과 항산화작용 및 arachidonic acid 생성 억제작용 (The Inhibitory Action of Free Radical and Arachidonic Acid Production and Cytotoxic Effects of Pini Resina)

  • 조경미;석귀덕
    • 약학회지
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    • 제46권5호
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    • pp.348-351
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    • 2002
  • In this report, anti-inflammatory, analgesic and cytotoxic effects of the water extracts of Pini Resina, which has been as an additive to oral hygienic products together with sodium chloride in community, were investigated. The water extracts of Pini Resina, pretreated Pini Resina and Ramus Mori Albae-added Pini Resina all showed relatively low cytotoxicity. All samples showed concentration-dependent increase in electron-donating capacity to DPPH, especially, Ramus Mori Albae-added Pini Resina was the highest in the extent. Arachidonic acid release from the cell membrane was significantly inhibited by the presence of the samples above, among those, Ramus Mori Albae-added Pini Resina was the most effective in the inhibitory action of the release.

Anti-Aspergillus Activities of Plant Essential Oils and Their Combination Effects with Ketoconazole or Amphotericin B

  • Shin, Seung-Won
    • Archives of Pharmacal Research
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    • 제26권5호
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    • pp.389-393
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    • 2003
  • The essential oils from Cedrus atlantica, Styrax tonkinensis, Juniperus communis, Lavandula angustifolia, Melaleuca alternifolia, Pelargonium graveolens, Pogestemon patchouli and Rosmarinus officinalis were analyzed by GC-MS. Antifungal activities of the oils were investigated by disk diffusion assay and the broth dilution method against Aspergillus niger and A. flavus. The effects of geraniol and the essential oil fraction from P. graveolens on the antifungal activity of amphotericin Band ketoconazole were examined using a checkerboard microtiter assay against both Aspergillus fungi. Most of the tested essential oils, with the exception of C. atlantica, J. communis, and P. patchouli, significantly inhibited growth of A. niger and to a lesser extent that of A. fIavus, with MICs (minimal inhibitory concentrations) in the range 0.78-12.5 mg/mL. The essential oil fraction of P. graveolens and its main components, geraniol and citronellol, exhibited additive effects with amphotericin B and with ketoconazole against both Aspergillus species, resulting in fractional inhibitory concentration (FIC) indices ranging from 0.52 to 1.00.

다짐온도에서 골재 거칠기와 아스팔트 피막두께에 따른 중온화 첨가제의 윤활특성 평가 (Evaluation of Lubrication Characteristics of WMA Additives for Different Roughnesses of Aggregate Surfaces and Film Thicknesses of Binders at a Compaction Temperature)

  • 이상재;조동우;황성도;이석근
    • 한국도로학회논문집
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    • 제15권5호
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    • pp.1-9
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    • 2013
  • PURPOSES : This study is to develop a method to evaluate lubrication of asphalt binder using WMA additives and compare their lubrication effects on two types of WMA additives and three types of asphalt film thicknesses. METHODS : This study is based on laboratory experiments and rheological analysis of the experimental results. Testing materials are aggregate diskes, asphalt, and WMA additives. The main testing method is stress sweep test by using dynamic shear rheometer (DSR). RESULTS : Sasobit gives more lubrication effects on film thicknesses 0.2mm and under but LEADCAP does on film thicknesses over 0.3mm. CONCLUSIONS : LVE-Limit is a better parameter to discern the lubrication effects on the thin film asphalt thickness. Both Sasobit and LEADCAP WMA additives provide effective lubrication at the compaction temperature.

Formulation of Carbon Nanotube Paste and Its Optimization for Field Emission Display Applications

  • Kim, Yong-C.;Sohn, K.H.;Cho, Y.M.;Yoo, Eun-H.;Lee, Dong-Gu
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2004년도 Asia Display / IMID 04
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    • pp.696-699
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    • 2004
  • Of the emissive display technologies, field emission displays using pasted carbon nanotubes offer several advantages over other competing cathode materials such as low driving voltage, possible large-area and low-cost processes. In this study, formulation of carbon nanotube paste and its electron field emission properties are characterized. Also the effects of additive powders and surface morphology on electron emission are reported.

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중성자 조사용 전기도체의 첨가물 효과 (Effect of Metal Oxide of Ceramic Superconductor for Neutron beam Irradiation)

  • 이상헌;최용
    • 전기학회논문지
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    • 제57권3호
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    • pp.429-432
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    • 2008
  • Much studies have been concentrated to develop the fabrication technique for high critical current density but still there are a lot of gap which should be overcome for large scale application of superconducting materials at liquid nitrogen temperature. The improvement of the critical current can be achieved by forming the nano size defect working as a flux pinning center inside the superconductor. In this paper, the establishment of fabrication condition and additive effects of second elements were examined so as to improve the related properties to the practical use of superconductor.

첨가제 활용에 따른 플라즈마 배연탈황탈질 특성 (Additive effects on $SO_x/NO_x$ removal characteristics using plasma)

  • 지평삼;엄희문;장경룡;남창모;지준화;한영욱
    • 한국대기환경학회:학술대회논문집
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    • 한국대기환경학회 1999년도 추계학술대회 논문집
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    • pp.260-261
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    • 1999
  • 산업시설 및 대형 발전설비에서 배출되는 아황산가스 및 질소산화물은 대기환경에 직접적으로 악영향을 미칠 뿐만 아니라, 오존의 생성과 고갈, 산성비의 출현등으로 지구 온난화와 같은 기후변화에 크게 기여하는 것으로 보고되고 있다. 기존의 습식 석회/석회석 탈황공정(FGD) 및 선택적 촉매/비촉매 탈질기술(SCR/SNCR)은 효과적인 상용기술로서 널리 연구개발되어 왔으나, 대단위 시설투자와 고비용, 2차 오염물질의 배출이 단점으로 지적되고 있다(Nam, 1999).(중략)

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슬래그를 혼합한 고온형 벨라이트 시멘트의 특성 (Properties of the Active Belite Cement with Slag)

  • 안태호;박동철;심광보;최상홀
    • 한국세라믹학회지
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    • 제36권6호
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    • pp.599-603
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    • 1999
  • In an effort to improve the mechanical properties of the belite cement active belite cement clinker was synthesized. Properties of the clinker were characterized by a XRD, FT-IE optical microscopy and SEM. The additive effects of slag on the hydration properties were investigated by the measurement of compressive strength heat evolution and SEM. The experimental results exhibited that the 3wt% borax was effective in stabilizing $\alpha$'-C2S and the addition of 5wt% anhydrite and 40wt% slag wee effective in the hydration.

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