• Microbiology and Biotechnology Letters
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• v.48 no.4
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• pp.423-428
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• 2020

In vitro evolution is a powerful technique for the engineering of yeast strains to study cellular mechanisms associated with evolutionary adaptation; strains with desirable traits for industrial processes can also be generated. There are two distinct approaches to generate evolved strains in vitro: the sequential transfer of cells in the stationary phase into fresh medium or the continuous growth of cells in a chemostat bioreactor via the constant supply of fresh medium. In culture, evolutionary forces drive diverse adaptive mechanisms within the cell to overcome environmental or intracellular stressors. Especially, this engineering strategy has expanded to the field of human cell lines; the understanding of such adaptive mechanisms provides promising targets for the treatment of human genetic diseases and cancer. Therefore, this technology has the potential to generate numerous industrial, medical, and academic applications.

• Journal of Communications and Networks
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• v.15 no.3
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• pp.301-311
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• 2013

This paper proposes a policy-based quality of service (QoS) management framework for adaptive routing decisions. We present an approach considering interior gateway protocol (IGP) for path discovery mechanisms and QoS-aware policies for configuring the network elements. The integration of the aforementioned modules into this policy-based network management (PBNM) system is demonstrated by conducting experiments in a real environment, the hellenic public administration network SYZEFXIS. These experiments combine different traffic conditioning mechanisms through event detectors, consider IP service level agreement mechanisms that interoperate with the PBNM system and analyze the enforcement of IGP and QoS policies. Finally, validation and measurement tools are used to prove the efficiency of this framework. It is shown that this architecture offers significantly increased performance and learning capabilities, while the PBNM system achieves adaptive QoS routing through automated configuration considering the avoidance of suboptimal routing issues or under-performance conditions of the network entities.

• PNF and Movement
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• v.6 no.1
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• pp.41-51
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• 2008

Purpose : This paper reviews evidence supporting adaptive plasticity in skeletal muscle fibers induced by various exercise training and neuromuscular activity. Result : Skeletal muscle fiber demonstrates a remarkable adaptability and can adjust its physiologic and contractile makeup in response to alterations in functional demands. This adaptive plasticity results from the ability of muscle fibers to adjust their molecular, functional, and contractile properties in response to altered physiological demands, such as changes in exercise patterns and mechanical loading. The process of activity-dependent plasticity in skeletal muscle involves a multitude of signalling mechanisms initiating replication of specific genetic sequences, enabling subsequent translation of the genetic message and ultimately generating a series of myosin heavy chain isoform. Conclusions : Knowledge of the mechanisms and interaction of activity-dependent adaptive pathways in skeletal muscle is important for our understanding of the synthesis of muscle myosin protein, maintenance of metabolic and functional capacity with physical activity, and therapeutic intervention for functional improvement.

• Journal of Power Electronics
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• v.15 no.5
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• pp.1274-1285
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• 2015

This paper deals with model reference adaptive system (MRAS) speed estimators based on a secondary flux for linear induction motors (LIMs). The operation of these estimators significantly depends on an adaptation mechanism. Fixed-gain PI controller is the most common adaptation mechanism that may fail to estimate the speed correctly in different conditions, such as variation in machine parameters and noisy environment. Two adaptation mechanisms are proposed to improve LIM drive system performance, particularly at very low speed. The first adaptation mechanism is based on fuzzy theory, and the second is obtained from an LIM mechanical model. Compared with a conventional PI controller, the proposed adaptation mechanisms have low sensitivity to both variations of machine parameters and noise. The optimum parameters of adaptation mechanisms are tuned using an offline method through chaotic optimization algorithm (COA) because no design criterion is given to provide these values. The efficiency of MRAS speed estimator is validated by both numerical simulation and real-time hardware-in-the-loop (HIL) implementations. Results indicate that the proposed adaptation mechanisms improve performance of MRAS speed estimator.

• Journal of Mechanical Science and Technology
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• v.14 no.1
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• pp.103-112
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• 2000

Numerical simulations of unsteady opposed-flow flames are performed using an adaptive time integration method designed for differential-algebraic systems. The compressibility effect is considered in deriving the system of equations, such that the numerical difficulties associated with a high-index system are alleviated. The numerical method is implemented for systems with detailed chemical mechanisms and transport properties by utilizing the Chemkin software. Two test simulations are performeds hydrogen/air diffusion flames with an oscillatory strain rate and transient ignition of methane against heated air. Both results show that the rapid transient behavior is successfully captured by the numerical method.

• Structural Engineering and Mechanics
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• v.6 no.8
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• pp.955-969
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• 1998

Engineering problems are inherently imprecision tolerant. Biologically inspired soft computing methods are emerging as ideal tools for constructing intelligent engineering systems which employ approximate reasoning and exhibit imprecision tolerance. They also offer built-in mechanisms for dealing with uncertainty. The fundamental issues associated with engineering applications of the emerging soft computing methods are discussed, with emphasis on neural networks. A formalism for neural network representation is presented and recent developments on adaptive modeling of neural networks, specifically nested adaptive neural networks for constitutive modeling are discussed.

• Journal of Contemporary Eastern Asia
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• v.16 no.1
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• pp.69-81
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• 2017

This study examines how South Korean governments responded to the outbreak of Middle East Respiratory Syndrome Coronavirus (MERS) using the adaptive governance framework. As of November 24, 2015, the MERS outbreak in South Korea resulted in the quarantine of about 17,000 people, 186 cases confirmed, and a death of 38. Although the national government had overall responsibility for MERS response, there is no clear understanding of how the ministries, agencies, and subnational governments take an adaptive response to the public health crisis. The paper uses the adaptive governance framework to understand how South Korean governments respond to the unexpected event regarding the following aspects: responsiveness, public learning, scientific learning, and representativeness of the decision mechanisms. The framework helps understand how joint efforts of the national and subnational governments were coordinated to the unexpected conditions. The study highlights the importance of adaptive governance for an effective response to a public-health related extreme event.

• Animal cells and systems
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• v.6 no.3
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• pp.187-193
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• 2002

It has long been recognized that exposure to low levels of toxic chemicals could have beneficial effects, such as increased resistance to related chemicals or stimulation of growth or development. The notion of radiation hormesis, that exposure to low levels of ionizing radiation could produce beneficial effects, developed seriously in the late 1950’s, and was, to most radiation scientists, incredible. This was due in pan to the then prevailing ideas of radiobiological mechanisms, in part to the sweeping generalizations made by the leading proponents of the radiation hormesis concept, and in pan to the many failures to confirm reports of beneficial effects. More recent understanding of the mechanisms of radiation damage and repair, and discoveries of induction of gene expression by radiation and other genotoxic agents [the adaptive response] make it seem inevitable that under suitable conditions, irradiation will produce beneficial effects.

• Journal of Information Technology Applications and Management
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• v.18 no.1
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• pp.15-39
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• 2011

A deeper understanding of how organizations behave as social complex adaptive systems is needed. In this paper we demonstrate how the Leadership Invigorating Flows of Energies model can help with this understanding. The model highlights the role of emergent leadership as a force encouraging the creation, diffusion, and utilization of knowledge through self-organizing mechanisms. We illustrate our approach by examining Wikipedia and show how it can be described as a social CAS. Our analysis of Wikipedia describes how emerging intrapreneurship behaviors result in dynamic flows of knowledge and self-organizing feedback mechanisms across the organization. We provide implications for organization studies and present evidence to support claims made by advocates of complexity theory. We conclude by proposing that Wikipedia can be seen as a new form of organization, and finish with a brief note highlighting a possible way forward.

• 제어로봇시스템학회:학술대회논문집
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• 2004.08a
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• pp.46-51
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• 2004

This paper presents an adaptive control method based on parameter linearization for incompletely restrained wire-suspended mechanisms. The main purpose of this control method is utilizing it in a walking assist service robot for elderly people. This method is computationally simple and requires neither end-effector acceleration feedback nor inversion of estimated inertia matrix. In the proposed adaptive control law, mass, moment of inertia and external force and torque on the end-effector are considered as components of parameter adaptation vector. Nonlinear simulation for walking an elderly shows the effectiveness of the parameter adaptation law.