• Informatization Policy
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• v.24 no.4
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• pp.17-43
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• 2017

The purpose of this study is to investigate the directions of information and communication technology(ICT) education in K-12 based on the analysis of ICT accessibility and utilization levels of Korean students. To this end, we analyzed the trends of Korea and OECD countries by survey period, focusing on the OECD PISA 'ICT familiarity survey' conducted in 2009, 2012 and 2015. The surveyed subjects were 15 year-old students and the analysis method was calculated based on the sampling weights. The results of the analysis of Korean students are as follows: First, ICT accessibility at home increased from 2009 to 2015, but was consistently lower than the OECD average. Second, the overall Internet usage time was lower than the OECD average. The Internet usage time on weekdays increased from 2012 to 2015, but on weekends decreased. Third, the ICT accessibility in schools decreased from 2009 to 2012, and increased in 2015, but was lower than the OECD average in 2015. Fourth, the student age ratio of first time computer usage increased from 2012 to 2015 and the average age for computer usage began before age 6, but was below the OECD average. Lastly, student use of digital devices for items such as Internet searches for entertainment and SNS activity has increased from 2012 to 2015, but the level of everyday use such as e-mail, online chat, program downloading, and reading Internet news has decreased. Based on these results, this study suggested policy plans for the improvement of ICT education for elementary and secondary school students in Korea.

• Journal of Pharmaceutical Investigation
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• v.30 no.3
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• pp.191-199
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• 2000

Genomics is providing targets faster than we can validate them and combinatorial chemistry is providing new chemical entities faster than we can screen them. Historically, the drug discovery cascade has been established as a sequential process initiated with a potency screening against a selected biological target. In this sequential process, pharmacokinetics was often regarded as a low-throughput activity. Typically, limited pharmacokinetics studies would be conducted prior to acceptance of a compound for safety evaluation and, as a result, compounds often failed to reach a clinical testing due to unfavorable pharmacokinetic characteristics. A new paradigm in drug discovery has emerged in which the entire sample collection is rapidly screened using robotized high-throughput assays at the outset of the program. Higher-throughput pharmacokinetics (HTPK) is being achieved through introduction of new techniques, including automation for sample preparation and new experimental approaches. A number of in vitro and in vivo methods are being developed for the HTPK. In vitro studies, in which many cell lines are used to screen absorption and metabolism, are generally faster than in vivo screening, and, in this sense, in vitro screening is often considered as a real HTPK. Despite the elegance of the in vitro models, however, in vivo screenings are always essential for the final confirmation. Among these in vivo methods, cassette dosing technique, is believed the methods that is applicable in the screening of pharmacokinetics of many compounds at a time. The widespread use of liquid chromatography (LC) interfaced to mass spectrometry (MS) or tandem mass spectrometry (MS/MS) allowed the feasibility of the cassette dosing technique. Another approach to increase the throughput of in vivo screening of pharmacokinetics is to reduce the number of sample analysis. Two common approaches are used for this purpose. First, samples from identical study designs but that contain different drug candidate can be pooled to produce single set of samples, thus, reducing sample to be analyzed. Second, for a single test compound, serial plasma samples can be pooled to produce a single composite sample for analysis. In this review, we validated the issue whether the second method can be applied to practical screening of in vivo pharmacokinetics using data from seven of our previous bioequivalence studies. For a given drug, equally spaced serial plasma samples were pooled to achieve a 'Pooled Concentration' for the drug. An area under the plasma drug concentration-time curve (AUC) was then calculated theoretically using the pooled concentration and the predicted AUC value was statistically compared with the traditionally calculated AUC value. The comparison revealed that the sample pooling method generated reasonably accurate AUC values when compared with those obtained by the traditional approach. It is especially noteworthy that the accuracy was obtained by the analysis of only one sample instead of analyses of a number of samples that necessitates a significant man-power and time. Thus, we propose the sample pooling method as an alternative to in vivo pharmacokinetic approach in the selection potential lead(s) from combinatorial libraries.

• Journal of the Korean association of regional geographers
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• v.22 no.1
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• pp.168-179
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• 2016

This study attempted to analyze the relationship between school life satisfaction and acculturation of elementary students of north Korean refugees in Daegu and Gyeongbuk region. The socio-demographic characteristics of elementary students in Daegu and Gyeongbuk were different from in capital territory or other parts of Korea. The acculturation of students living in Daegu and Gyeongbuk was distinctive. The proportion of assimilation was slightly higher than that of integration. However, 42 percent of students belonging to separation and marginalization passively accepted south Korean culture, so that they would have a difficult time in adjusting to new culture. Students getting older and being used to school life strongly inclined to accept south Korean culture; while, students born in north Korea tended to resist acceptance of south Korean culture. Most students were satisfied with school life. The satisfaction level was high in the relationship with teachers and school environment; while, the satisfaction level in learning activity was relatively low. In the relationship between school satisfaction and types of acculturation, students actively accepting new culture were relatively highly satisfied with their school life. A standardized short-term education oriented program for north Korean adolescents refugees living in south Korea should be shifted into the long-term support policy reflected in class and attribute in terms of acculturation.

• Journal of Applied Biological Chemistry
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• v.59 no.4
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• pp.365-372
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• 2016

The objective of the present study was to evaluate the protective effect of red ginseng (RG) according to steaming time on 150 mM HCl/60 % ethanol induced gastric ulcer models in mice. The sample was divided into 3 groups-G (dried ginseng), RG 4 (steamed 4 h and dried ginseng), RG 6 (steamed 6 h and dried ginseng), and determined through in vitro experiments, such as 1,1-diphenyl-2-picrylhydrazyl and 2,2'-azinobis-3-ethyl-benzothiazoline-6-sulfonic acid radical scavenging activity, HPLC analysis, total polyphenol, and flavonoid contents. In vitro experiment results were depended on steaming hours. Based on the results, we chose two samples (G, RG 6) and conducted in vivo experiments. Mice were divided into 5 groups: Nor (normal group), Con (acute gastritis mice treated with distilled water), G (gastris induced by HCl/Ethanol treated with 100 mg/kg G), RG 6 (gastris induced by HCl/ethanol treated with 100 mg/kg RG 6), and SC (gastris induced by HCl/Ethanol treated with 10 mg/kg sucralfate). In our results revealed that RG 6 suppressed elevated reactive oxygen species, and inflammatory related makers, such as cyclooxygenase-2, inducible nitric oxide synthase, tumor necrosis factor alpha, and interleukin-1 beta. In addition, gastric lesion area was improved. These results suggest that RG 6 protects the stomach by attenuating oxidative stress and inflammatory response under gastric ulcer conditions. Therefore, RG 6 should be a potential therapeutic agent for the treatment of acute gastric ulcer.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.30 no.2
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• pp.46-63
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• 2012

The object of this study was to analyze the speciality of Korean traditional waterscape and unique landscape formed with reflection of the phases of the time sat the area of Juhabru(宙合樓) in Changdeok Palace as a basic research to find the prototype of Taeaek pond at Changdeok Palace and restoration of the palace. Originally, Taeaek pond at Changdeok Palace was constructed in KingInjo(仁祖) period as a name of Yongji(龍池), later it called Taeaek pond after King Sukjong(肅宗). There is an island as a symbol of the immortal isle, and Chungseojeong(淸署亭), Taiksujae(澤水齋) and Buyongjeong(芙蓉亭) which were built to view the waterscape in Taeaek pond. Buildings were built asymmetrical balance around Taeaek pond because of the morphological character of tetragonal pond. Arrangement of this area has a definite form of axial structure. Yeolgokwan(閱古觀) Gaeyuwa(皆有窩), pavilions, bridges, islands, Osumoon(魚水門) and Juhabru are located on the north and south axis, and island and Osumoon play a role as a intersection and form an east of west axis. In this study, manual of construction for an island and pavilions is provided by analyzing transformational process of island and pavilions at Taeaek pond. Furthermore, kings and officials used to statically enjoy the view around Taeaek pond area, but dynamic fishing and boating activity happened in King Jungjo(正祖) period. These historical backgrounds have an influence on the spatial organization of Taeaek pond. For instance, bridge between Taeaek pond and island was destroyed with the increase of the importance of boating. Symbolic structure around Taeaek pond means 'fish changes to dragon' and 'both of king and officials become one'. Taiksujai, carving fish, Osumoon and Juhabru are provided as a related spatial factors.

• Korean Journal of Child Education & Care
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• v.17 no.3
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• pp.111-151
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• 2017

The purpose of this study is to investigate the perception and actual condition of early childhood teachers about the activities of cooperative art in early childhood education institutions. The subjects of the study were 280 teachers of early childhood education institutions in Y city. The research method was a questionnaire survey on the perception and actual condition of the cooperative art activities. For the research problems, frequency, percentage, and average were calculated by using descriptive statistics, and t - test, F - test, and ${\chi}^2$ - test were conducted to examine the differences according to background variables of early childhood teachers. In conclusion, this study showed that the need for cooperative art activities of early childhood education institutions was highly perceived, and there were significant differences according to the background variables of teachers in educational goals, contents and method. There were significant differences according to the teachers' background variables in the actual cooperative art activities in terms of frequency, method, time, evaluation method, teacher training and support. Based on the results of this study, various supporting methods such as activities plan and method, teacher education and training appropriate for the cooperative art activity program and the presentation of young children are sought so that more desirable and efficient cooperative art activities can be operated in the field of early childhood education suggesting that it should be done.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.9 no.2
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• pp.190-200
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• 2002

Purpose; The purpose of this study was to develop an instrument to measure sexual satisfaction in Korean adults. Method: Development of items for the instrument was done by a collecting, reorganizing, reducing and selecting process based on the literature. A total of 19 items were selected in this process. For evaluation of the appropriateness of the 19 items, questionnaires were given to an expert group consisting of 18 professionals (7 men and 11 women). Eighteen items having a response of 70% in 'very good' item or 'good' item were included as items for the instrument. With these 18 items, a 5 point Likert scale was developed, and reliability and validity tests of the scale were done. The subjects for the test were 1,127 Korean adults living in 11 areas in Korea, Data were collected from Dec. 1, 2000 to Feb. 28, 2001 and analyzed with SPSS/PC+ 10.0 program. Item analysis and factor analysis were used to assess the reliability and validity of the scale. Chronbach alpha and corrected item-total correlation were obtained to verify internal consistency, and principal component analysis with the varimax rotation was used to identify structure validity of the developed tool. Result: Reliability of the scale was .9503 and corrected item-total correlations of the items were distributed from .5208 to 7899. As a result of the factor analysis, the items were categorized into three factors. The cumulative variance of the three factors was 67.1%, and all of the variances of the factors were above 5%. Because factor 1 (8 items) indicated a special feeling of psychological satisfaction with sexual activity, it was named 'psychological factor'. Factor 2 (8 items) indicated a feeling of satisfaction in the interaction with sexual partner through communication and variation, therefore it was named 'interactional factor'. Factor 3 (2 items) was about the frequency and duration of sexual intercourse and indicated physical dimensions of satisfaction, so it was named 'physical factor'. The average score for sexual satisfaction of the 1,127 subjects was 65.32 (${\pm}12.71$), and histogram of the score showed a normal distribution with skewness - .425. Conclusion: Finally, a Korean Sexual Satisfaction Scale(KSSS) was accepted as a 5 point Likert scale with 18 items after the statistical test for reliability and validity. In conclusion, KSSS is a useful instrument which is valid and reliable can be used to understand the sexuality of Korean adults.

• Journal of Korean Academy of Rural Health Nursing
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• v.7 no.1
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• pp.5-17
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• 2012

Purpose: The objectives of this study were to investigate the prevalence of the metabolic syndrome (MetS) and to identify associated factors with MetS among rural residents. Methods: Data were collected from 1,196 subjects over aged 30 years by a self-administered questionnaire, physical measurement, and blood test in a rural area. The prevalence of MetS was determined by the criteria of the American Heart Association/National Heart, Lung, and Blood Institute (AHA/NHLBI) and 2005 the Korean society for the study of obesity. Results: The prevalence of MetS was 40.5% for men, 49.2% for women. The prevalence of risk factors of MetS was 57.4% for elevated blood pressure, 49.0% for low HDL-cholesterol, and 48.6% for abdominal obesity. Unemployment and higher Body mass index (BMI) were associated factors for MetS regardless of gender. And higher age and physical inactivity in women only increased the odds of the MetS. Especially, BMI was a strong risk factor of MetS in both men and women. Conclusion: The prevalence of metabolic syndrome was higher in a rural area. Therefore, health care providers should develop lifestyle modification program to increase physical activity level and to prevent the obesity among rural residents in order to decrease the prevalence of MetS.

• Korean Journal of Occupational Health Nursing
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• v.3
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• pp.71-85
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• 1993

The objective of this study is to describe the frequency of workplace health promotion activites. For this objective, questionaire was requested to 648 trainees of Korea Industrial Safety Corporation. Respondents' positions were safety manager, health care manager, or representatives of employee. Major findings are as follows: 1) Of responding workplaces, 66.2% supported the activities related to promote employees' health. The support rate was higher of Manufacturing and Tranport than others. And the lager workplaces had the higher support rate. 2) Most frequent activity is exercise program. But the prevalence of smoking cessation, stress management, nutrition education and women health care was very low. Major contents of support were to pay the cost of these activites and to equip the places or the facilities. 3) 24.9% had the non-smoking policy in the workplace. 98.6% equiped the places and facilities for employees. Mean number of facilities across all workplaces was 2.96 and that of exercise circles was 3.60. In conclusion, it was suggested that the stratege was needed to develop the Korean model for workplace health promotion on the basis of exisiting activites.

• Resources Recycling
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• v.26 no.3
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• pp.79-91
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• 2017

The core of Hydrogen Fuel Cell Vehicles (FCV) is polymer solid fuel cell (PEFC), and the core material that generates electrochemical electricity in the cell is platinum catalyst. Platinum is localized in South Africa and Russia, and the world production of Pt is about 178 tons per year, which is expensive and recycled. At present, the amount of Pt used in PEFC is $0.2{\sim}0.1mg/cm^2$. In order to reduce the price of the battery and increase the FCV supply, the target is to reduce the amount of Pt used to $0.05{\sim}0.03mg/cm^2$. $Pt-Pd/Al_2O_3$, Pt/C, Pt/GCB, Pt/Au/C, PtCo/C, PtPd/C, etc. by using polyol method using nano Pt, improved Cu-UPD/Pt substitution method and nano-capsule method, Have been researched and developed, and there have been reported techniques for improving the activity of Pt catalysts and stabilizing them. This paper investigates the production technology of nano-Pt and nano-Pt catalysts, recycling of spent Pt catalysts and application trends of Pt catalysts.