• Korean Institute of Interior Design Journal
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• v.22 no.6
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• pp.108-118
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• 2013

This study has analyzed the process of space information perceived and recognized through the estimation of observation frequency and number according to the time range of observation data acquired from observation experiment with the object of hospital lobby. The followings are the results analyzed at this study. First, the continual observation of 3 and 6 times was attentive and conscious for probing to find an object rather than for acquiring exact information and that of 9 times could be regarded as the time for acquiring visual appreciation. However, the repetitive occurrence of high and low frequencies can be thought of repetitive acts for visual appreciation. Second, the continual observation of 3 and 6 times had the highest observation frequency of II, while that of 9 times had the highest observation frequency of III. In case of 3 and 6 times, the observation frequency had the tendency to become a little higher after being low since V, and in case of 9 times it had the repetition of becoming low and high and from IX it characteristically got higher. This feature can be thought to be the process that the subject repeats the fixation and movement of observation at a visual activity for perception and recognition. In the process of first observation, the observation frequency was the highest after 20 seconds or so, but since then, it gets lower and repeatedly gets higher and lower as time passes. After 90 seconds, the frequency showed the tendency of getting higher continuously. Third, the examination of changing features of frequency may show the characteristics of exploration for and attention to space but if the observation frequency is not associated with observation times for analysis there will a limitation that the features of observation frequency cannot be clarified. Accordingly, the simultaneous analysis of both is very effective for estimating the observation characteristics seen at the processes of perception and recognition. Fourth, the general analysis of the both revealed: with the progress of observation time the discontinuous space exploration decreased, and as the observation time got longer the fixed attention to a specific spot increased. Fifth, in order to estimate the observation characteristics by the change of time range the observation frequency and times by trend line was analyzed, which approach seems to be an appropriate technique that can comprehensively show the overall flow of time series data.

• IMMUNE NETWORK
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• v.11 no.3
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• pp.175-181
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• 2011

Background: CM1 (centrocyte/-blast marker 1) was defined by a mAb against concavabalin-A (ConA) activated PBMC. It is expressed in germinal center of human tonsil and on the surface of activated PBMC as well as cancer cells. Recently, increased productions of pro-inflammatory mediators were detected from activated PBMC by CM1 ligation. Methods: However, there is a limitation to explain the exact role of CM1 on inflammation and its related mechanisms, since the identity of CM1 is still not clarified. In our previous study, we have already confirmed that soluble form of CM1 was produced by Raji. Therefore, we performed Q-TOF analysis after immunoprecipitation of concentrated Raji culture supernatant using anti-CM1 mAbs. Results: As a result, we found that CM1 is identical to enolase-1(ENO1), a glycolytic enzyme, and we confirmed that results by silencing ENO1 using siRNA. It was also confirmed through competition assay between anti-CM1 and anti-ENO1 mAbs. Finally, we investigated the possible role of CM1 in inflammatory response and cancer. The ligation of CM1 on Raji cells with anti-CM1 mAbs induces the extensive production of prostaglandin $E_2(PGE_2)$. In addition, the increased activity of matrix metalloproteinase (MMP)-2/9 was shown in NCI-N87, stomach cancer cell line by CM1 stimulation. Conclusion: CM1 is identical to ENO1 and it might be an important role in the regulation of inflammatory responses.

• Journal of the Korean Arthroscopy Society
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• v.5 no.2
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• pp.63-68
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• 2001

Purpose : To propose the diagnosis, 'hypertrophy of the anterior cruciate ligament(ACL)', and its clinical, radiological and pathological characteristics. Materials & Method : Since Dec. 1995, we have experienced 10 patients(12 knees) with hypertrophy of the ACL. There were 2 males and 8 females, and the age of the patients ranged from 35 to 67 years. Characteristics of clinical, radiological and pathological findings were analysed. Results : The chief complaint was insidious onset of dull pain on the knee which became worse with activity. The constant physical finding was painful limitation of full extension of the knee. Sagittal MR images showed diffuse swelling of the ACL, similar finding that could be seen in acute ACL tear. Arthroscopically, noted was a marked enlargement of the ACL causing notch impingement. Biopsies of the hypertrophied ACL showed increased collagenous tissue with variable degree of myxoid degeneration. With partial excision of the hypertrophied ACL with or without notchplasty, the symptoms improved in all. Conclusion : Hypertrophy of the ACL, a newly proposed diagnosis, should be considered be determining the cause of the painful knee, and further study should be done about its pathogenesis.

• Journal of Korea Society of Industrial Information Systems
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• v.22 no.3
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• pp.77-94
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• 2017

This Paper is the Thesis that Reports Empirical Results on the Effect of Maintaining Behavior of Native Culture on the Job Attitude of Immigrant Labor and the Mediating Effect of Psychological Well-being. In order to Accomplishment this Goal, an Empirical Study was Implemented. The Data for an Empirical Study was Obtained from the Survey on 205 Immigrant Labor from Vietnam in Busan and Gyeongsangnam-do. And Multiple Regression Analysis was Conducted to Examine the Research Hypothesis. The Summary of Empirical Study's Results is Follows. 1) Among Maintaining Behavior of Native Culture, Native Culture-related Media Behavior, Meeting with Native Companions and Persistence of Native Religious Activity have the Positive Effect on the Job Attitude Significantly. 2) Eating Native Food have the Negative Effect on the Job Satisfaction Significantly. 3) There are Mediating Effects of Psychological Well-being on the Relationship Between the Maintaining Behavior of Native Culture and Job Attitudes. Maintaining Behavior of Native Culture has Significant Positive Effect on Job Involvement and Job Satisfaction Indirectly Via Mechanisms Such as the Spillover Effect of Psychological Well-being. That is, The more Immigrant Workers do Maintaining Behavior of Native Culture, the Higher Psychological Well-being is and it Improves Their Job Involvement and Job Satisfaction. The Implication of these Results, the Limitation of this Study and the Direction of Future Study were Suggested.

• Science of Emotion and Sensibility
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• v.20 no.3
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• pp.169-180
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• 2017

Individuals with high trait anxiety try to suppress their anger expression, thus there are limits in measuring their anger using subjective behavioral evaluation. In order to overcome this limitation, this study attempted to identify the difference in the autonomic nervous system responses induced by anger in individuals with high trait anxiety. Participants were divided into two groups, anxiety and control groups. Electrocardiogram (ECG), respiration (RESP), electrodermal activity (EDA), and skin temperature (SKT) were measured while participants were presented with an anger-inducing stimulus. Heart rate (HR), standard deviation of NN interval (SDNN), root mean square of successive difference (RMSSD), low frequency (LF), high frequency (HF), LF/HF ratio, respiration rate (RR), skin conductance level (SCL), and maximum skin temperature (maxSKT) were calculated before and after presenting the stimulus. Anxiety group reported greater anger by the anger-inducing stimulus compared to the control group. Anxiety group also showed significant increase in SDNN and LF, and decrease in HF, LF/HF ratio, and RR. These results suggest that the autonomic nervous system responses may be used as objective indicators of anger experiences in individuals with high trait anxiety.

• Molecular & Cellular Toxicology
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• v.1 no.3
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• pp.172-178
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• 2005

[ $21{\alpha}$ ]- and ${\beta}$-Methylmelianodiol were isolated as the inhibitor of IL-5 bioactivity from Poncirus tripoliata. To develope as an anti-septic drug, the genotoxicity of $21{\alpha}\;-and\;{\beta}-methylmelianodiol$ was subjected to high throughput toxicity screening (HTTS) because they revealed strong IL-5 inhibitory activity and limitation of quantity. Mouse lymphoma thymidine kinase ($tk^{+/-}$) gene assay (MOLY), single cell gel electrophoresis (Comet) assay in mammalian cells and Ames reverse mutation assay in bacterial system were used as simplified, inexpensive, short-term in vitro screening tests in our laboratory. These compounds are not mutagenic in S. typhimurium TA98 and TA100 strains both in the presence and absence of metabolic activation. Before performing the comet assay, $IC_{20}$ of $21{\alpha}-methylmelianodiol$ was determined the concentration of $25.51\;{\mu}g/mL\;and\;21.99\;{\mu}g/mL$ with and without S-9, respectively. Also $21{\beta}-methylmelianodiol$ was determined the concentration of $24.15\;{\mu}g/mL\;and\;\;22.46\;{\mu}g/mL$ with and without S-9, respectively. In the comet assay, DNA damage was not observed both $21{\alpha}-methylmelianodiol\;and\;21{\beta}-methylmelianodiol$ in mouse lymphoma cell line. Also, the mutant frequencies in the treated cultures were similar to the vehicle controls, and none of $21{\alpha}\;-and\;{\beta}-methylmelianodiol$ with and without S-9 doses induced a mutant frequency over. twice the background. It is suggests that $21{\alpha}\;-and\;{\beta}-methylmelianodiol$ are non-mutagenic in MOLY assay. The results of this battery of assays indicate that $21{\alpha}\;-and\;{\beta}-methylmelianodiol$ have no genotoxic potential in bacterial or mammalian cell systems. Therefore, we suggest that $21{\alpha}\;-and\;{\beta}-methylmelianodiol$, as the optimal candidates with both no genotoxic potential and IL-5 inhibitory effects must be chosen.

• Journal of muscle and joint health
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• v.6 no.1
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• pp.100-135
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• 1999

Typical symptoms of rheumatic disease affect overall daily living and cause severe stress. Individuals afflicted with rheumatic disease have many illness-related stresses. Pain was the predominantly perceived stress followed by limitation in mobility, difficulties in carrying out activities of daily living. helplessness, dependency on others, threat to self-esteem, interference in social activity, interference in family relationships. difficulties performing at work, and discomfort of the treatment. Patients with chronic arthritis are subjected to long periods of continuous stress, which may require the management by the health care provider. In these cases, the purpose of the nursing is helping to promote health through supporting patient's coping. Therefore, for the nursing intervention to be effective, it is critical to build a theoretical framework that describes stress-coping for chronic arthritis. Thus, the purpose of this dissertation is to present a theoretical framework which describes the stress-coping processes and to empirically test pathos of this framework for the people with chronic arthritis. The foundation upon which this framework is built in the Erickson, Tomlin, and Swain(1983) theory of Modeling and role-Modeling. The subjects were 275 patients with rheumatoid arthritis or osteoarthritis who visited the outpatient clinic. A hypothetical model of stress-coping was tested by covariance structure analysis with PC-LISREL 8.12 program. As a result, the overall fit was good(Chi-square=94.49, P=0.00, RMR=0.067, GFI=0.95, AGFI=0.91, NNFI=0.93, NFI=0.91) for the hypothetical model. The results of hypothesis testing were as follows : Basic need satisfaction had a statistically significant influence on illness-related experience, emotional stress and coping resources. Internal health locus of control had a statistically significant influence on coping resources. However, independent variables(basic need satisfaction, internal health locus of control, illness-related experience, emotional stress and coping resource) did not have significantly influence on coping. And then, the hypothetical model was modified by considering both the theoretical implication and statistical significance of the parameter estimates. The revised model had a better fit to the data(Chi-square=83.11(P=0.00), RMR=0.061, GFI=0.96, AGFI=0.92, NNFI=0.95, NFI=0.92). Hypothesis emerged from the revised model was tested. The results of hypothesis testing were as follows : Basic need satisfaction had a statistically significant influence on illness-related experience, emotional stress and coping resources. Internal health locus of control had a statistically significant influence on illness-related experience and coping resources. Internal health locus of control, illness-related experience, emotional stress and coping resources had a significantly influence on coping. According to the results of this dissertation, basic need satisfaction and internal health locus of control play a central role in appraisal of illness-related experience and coping resources. And illness related-experience, emotional stress, and coping resources affect on coping activities. In summary, nursing interventions to enhance basic need satisfaction and internal health locus of control will decrease illness related experience and emotional stress and increase coping resources. Increased coping resources will prompt coping activities.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.14 no.3
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• pp.655-668
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• 1994

Conventional deodorization filters using soil and compost reach the capacity limitation of deodorization in short period, because its removal mechanism primarily depends on adsorption. Therefore, in this study the experiment was performed on the removal of ammonia which is a strong inorganic malodor, frequently emitted from night soil treatment plants and sewage treatment plants, by seeding activated sludges on the bio-peat containing higher organic contents, water conservation capacity, permeability and lower pressure drop. As a result, in raw peat filter natural ammonia outlet was observed in consequence of pH increase resulted from ammonia ionizing in liquid phase. Ammonia removal mechanism primarily depended on the adsorption onto the anion colloidal substances in peat. In peat bio-filter, theoretical ammonium salts ratio was higher than that of raw peat, resulted from slight pH increase by microorganism activity, however, the experimetal value of ammonia-nitrogen accumulated in bio-peat was lower than that of raw peat because of nitrification by nitrifying bacteria. In the initial reaction period, adsorption was predominant in the ammonia removal mechanism, but nitrification was conspicuous after the middle period. Mass balance of nitrogen was established using experimental data of input $NH_3$ loading, output $NH_3$ loading, $NH_4{^+}$-N, $NO_x$-N, and Org-N. The critical time of unsteady state, which is the maximum activating point of microorganism in bio-filter, was determined using experimental data, and the ammonia adsorption curve was computed using regression analysis. On the basis of the results obtained by above analysis, the delay days for the saturation of adsoption capacity in peat bio-filter was calculated.

• Journal of the Korean Society of Food Culture
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• v.17 no.2
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• pp.197-213
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• 2002

In order to establish the processing condition of rapid- and low salt-fermented liquefaction of anchovy (Engrulis japonica), effect of temperature on crude enzyme activity of anchovy viscera, pretreatment conditions, and the minimum content of adding NaCl were investigated. The minimum limitation of NaCl content for anchovy liquefaction was 10%. Sample A(water adding, heating, adding 10% NaCl): chopped whole anchovy adding 20% water and then heating for 9 hrs at $50^{\circ}C$ and then adding 10% NaCl and then fermented at room temperature$(8-29^{\circ}C)$ for 180 days. Sample B(water adding, heating, adding 13% NaCl): chopped whole anchovy adding 20% water and then heating for 9 hrs at $50^{\circ}C$ and then adding 13% NaCl and then fermented at room temperature for 180 days. Sample C(adding 13% NaCl): chopped whole anchovy and then adding 13% NaCl and then fermented at room temperature for 180 days. Sample D(adding 17% NaCl): whole anchovy adding 17% NaCl and then fermented at room temperature for 180 days. The content of free amino acids such as aspartic acid, serine and threonine fluctuated severely according to the pretreatment methods. Possibly they might be recommend quality indices of standardization for salt-fermented liquefaction of anchovy. As for the relation between fermentation period(X) and individual free amino acid(Y), five kinds of free amino acids such as glutamic acid, valine, glycine, lysine, and alanine showed highly significant in their coefficient of determination in most of samples. They might be recommend as quality indices for salt-fermented liquefaction of anchovy during fermentation. The difference of taste between products of the rapid- and low salt-fermented liquefaction and the traditional salt-fermented liquefaction were caused by their composition of the free amino acids ratios, in which were umami, sweet, and bitter taste in the extracts of anchovy during fermentation. The appropriate fermentation period of the sample A was shorten 30 days than the sample B and 60 days than the samples C and 90 days than the sample D in the processing of anchovy.

• The Journal of the Korea Contents Association
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• v.9 no.8
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• pp.294-308
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• 2009

It is growing a necessity of consideration and management to the relevant policies for the elderly Patriots and Veterans systematically in order to increase the life-supported services since the rapid growth of the aging society. It is difficult to ensure the outcome of cost-effectiveness about the policies because of the residual welfare view and the limitation of the government budget in terms of the traditional Bohun(Korean independent movement activists, veterans and sacrificed advocators for democratization) service, though. In addition, it is not realized the individual activity and daily life-supported services yet to the elderly Patriots & Veterans since the concentration of security income and medical care. Accordingly, it is proper to quest a new Bohun policy from the traditional residual welfare view to universal or ubiquitous welfare service, which will enable them to get the various care service benefit in terms of cost-effectiveness. In this vein, the study is trying to figure out the alternative supply mechanism in-home care service to the elderly Patriots and Veterans; especially, the study emphasizes on the linkage between the regional social welfare service system and Bohun welfare service system.