• Archives of Pharmacal Research
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• v.25 no.5
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• pp.643-646
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• 2002

The succinic semialdehyde dehydrogenase (SSADH) inhibitory component was isolated from the EtOAc fraction of Lactuca sativa through repeated column chromatography; then, it was identified as phytol, a diterpenoid, based on the interpretation of several spectral data. Incubation of SSADH with the phytol results in a time-dependent loss of enzymatic activity, suggesting that enzyme modification is irreversible. The inactivation followed pseudo-first-order kinetics with the second-rate order constant of $6.15{\times}10^{-2}mM^{-1}min^{-1}.$ Complete protection from inactivation was afforded by the coenzyme $NAD^{+}$, whereas substrate succinic semialdehyde failed to prevent the inactivation of the enzyme; therefore, it seems likely that phytol covalently binds at or near the active site of the enzyme. It is postulated that the phytol is able to elevate the neurotransmitter GABA levels in central nervous system through its inhibitory action on one of the GABA degradative enzymes, SSADH.

• The Journal of the Korea Contents Association
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• v.13 no.7
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• pp.91-101
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• 2013

At the age of uncertainty, the contemporary architecture has been changed by various design approaches as a result of the development of the media. Especially, being issued Phenomenology by Merleau-Ponty the tendency of visual interpretation on the architectural space has been studied positively. This research is to understand a Phenomenological approach to design the interior and architectural space. The phenomenological architectural space is based on knowing about the perception from a body and experience as a contents of the world. The touch from the space designed by Phenomenological architectural express by various way of the Phenomenological light is one of the concept of Phenomenological experience.

• Journal of Communications and Networks
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• v.13 no.2
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• pp.113-124
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• 2011

Electrocardiography (ECG) is a widely accepted approach for monitoring of cardiac activity and clinical diagnosis of heart diseases. Since cardiologists have been well-trained to accept 12-lead ECG information, a huge number of ECG systems are using such number of electrodes and placement configuration to facilitate fast interpretation. Our goal is to design a wireless ECG system which renders conventional 12-lead ECG information.We propose the three-pad ECG system (W3ECG). W3ECG furthers the pad design idea of the single-pad approach. Signals obtained from these three pads, plus their placement information, make it possible to synthesize conventional 12-lead ECG signals.We provide one example of pad placement and evaluate its performance by examining ECG data of four patients available from online database. Feasibility test of our selected pad placement positions show comparable results with respect to the EASI lead system. Experimental results also exhibit high correlations between synthesized and directly observed 12-lead signals (9 out of 12 cross-correlation coefficients higher than 0.75).

• Journal of the Korean housing association
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• v.12 no.3
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• pp.41-49
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• 2001

This study attempts to present a new interpretation of the Jeju province Waga, authorized as Jeju province Folklore, in the context of lifestyles of residents distinctive in the Jungji, Chatbang, and Gopang system. Study results uncovered that (1) only one Jungji, a traditional house kitchen, exists in one house boundary, in the form of detached building in the 4 units of Gaok (K-2 Gaok, K-3 Gaok, C-1 Gaok, and C-2 Gaok) (2) Chatbang had multifaced-functions; as a place for diet for mistress and children, a place for preparing meals for a mister who diet in the room, and as an auxiliary meal-preparation facility in time of domestic celebration day. (3) Gopang was mostly a place for grain storage, and K-3 Gaok has one unit, K-1 Gaok, C-1 Gaok, and C-2 Gaok had 2 units, and K-2 Gaok and H Gaok had 3 untis of Gopang. (4) Jungji and Chatbang were correlated for meal preparation and diet while activity-line of flow was divided each other. (5) Jungji and Gopang were located at the opposite edges of of each house, revealing no consideration of indoor activities. (6) The ratios of space of Jungji, Chatbang and Gopang out of the whole house space were, average 23% in the case of Jungji located in the inner house, and average 37% in the case of Jingji located in the detached building, average 14% larger in the case of detached Jungji system.

• Korean Journal of Community Nutrition
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• v.5 no.2
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• pp.343-351
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• 2000

The Korean government enacted the National Health Promotion Act in January, 1995 and proclaimed its regulations and rules in September 1995, which became the basis of the national health policy. The health promotion programs consist of education for health, prevention of diseases, improvement of nutrition, and practice of healthy life style as defined in that Act. The Community Health Act was amended in 1995, which included implementing nutrition services in community health centers. The purpose of this report is to summerize the nutrition services conducted in 32 community health centers. the main nutritional activities were as follows : 1) nutritional guidance by counseling and education for pregnant or lactating women, infants, preschool children, and those with chronic diseases, 2) collection, analysis, and interpretation of data collected from the community, on background conditions and target population for the assessment of community needs, 3) evaluation of nutritional status of population in the community 4) nutritional guidance for mass feeding in different institution including schools and welfare institutions. In order to meet the government's expectations and desires, the community health centers have made continuous efforts to put nutritional activities into practice in the community. However, there are constraints, such as relative staff shortages, lack of funds, and information which hampers the nutritional activities.

• Natural Product Sciences
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• v.16 no.2
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• pp.68-74
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• 2010

Phytochemical investigation on the ethyl acetate and n-butanol fractions of Moutan Cortex resulted in the isolation and characterization of a new monoterpene glycoside (3) and twenty known monoterpene glycosides (1, 2, 4-21). The structure of 3 was determined by spectroscopic data interpretation and physico-chemical properties. Compounds 1 and 8 presented a remarkable inhibitory activity against lipoxygenase-1 (LOX-1) with $IC_{50}$ values of 45.2 and $37.5\;{\mu}M$, respectively. Compounds 9, 10, 13, 18, 19, and 21 showed significant 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging effect with $IC_{50}$ values of 9.8, 25.5, 6.4, 15.2, 18.7, and $23.7\;{\mu}M$, respectively. Benzoylpaeoniflorin (8), which exhibited the highest inhibitory effect with an $IC_{50}$ value of $37.5{\pm}0.7{\mu}M$, was further analyzed the inhibition kinetics by Lineweaver-Burk plots. Results indicated that 8 is a non-competitive inhibitor, and the kinetic parameter values were estimated to be ($31.04\;{\mu}M$, Ki), ($0.29\;{\mu}M/min$, $V_m$), and ($48.50\;{\mu}M$, $K_m$).

• Proceedings of the Korean Vacuum Society Conference
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• 2000.02a
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• pp.137-137
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• 2000

The surface collective modes of thin K films deposited on Al(111) have been investigated using frequency dependent photoyield measurements and momentum resolved inelastic electron scattering. Jellium based theoretical calculations have predicted a richer set of features in the thin films than for the surface of a semi-infinite solid because there are th interference between two interfaces (substrate-film and film-vacuum) and heavy damping on the substrate. The use of an optical probe and electron scattering has allowed us to draw a more complete picture of the dynamic screening in thin films. The number, dispersion, damping and optical activity of the collective modes of the thin films have been measured as a function of K film thickness. New overlayer-induced excitations are observed : At qII=0, they correspond to the antisymmetric slab mode and the multipole surface plasmon. At finite qII=0, these modes undergo a transition towards the K multipole and monopole surface plasmons. With increasing coverage, the overlayer excitations turn into the collective modes of semi-infinite K. For a consistent interpretation of photoyield and electron energy loss spectra it is crucial to account for the non-analytic dispersion of the overlayer modes at small parallel wave vectors and for the finite angular resolution of the detector. The observed dispersions confirm predictions based on the time-dependent density functional approach.

• Journal of Marine Bioscience and Biotechnology
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• v.5 no.4
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• pp.46-50
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• 2011

Phytoplankton forms the base of sea ecosystems. Various environmental factors and anthropogenic pollution, primarily, affect the concentration and photosynthetic activity algal cells, and the changes in the phytoplankton photosynthesis influence other elements of aquatic ecosystems. The increase in anthropogenic pollution markedly damages natural aquatic ecosystems, particularly, in the coastal zones, where an intense blooming of microalgae occurs, including the release of highly dangerous ecotoxic substances of various chemical natures (red tides). In this study, we tried to apply as a parameter for the algal blooming prediction in the ocean from fluorescence values in the taken samples around Busan coastal area. F0 value was almost constant but Fv/Fm value showed the irregular pattern. We presume that these results are due to the changes of the ocean environment and climate. To predict or give early warning the algal blooming, we need to investigate the specific area or fixed area through real-time monitoring. Especially, algal blooming prediction or warning can be achieved via continuously monitoring and interpretation of fluorescence changes.

• Journal of architectural history
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• v.27 no.6
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• pp.41-48
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• 2018

For the proper preservation and utilisation of Regional Modern Heritage Buildings, it is necessary to study the history of local modern architecture based on a broad understanding of the region and also to architectural history. The aim of this study is expand the awareness and multi-faceted interpretation of modern architecture in Kwangju in the 1940's to 1950's, by exploring the origin of regional modern architecture from new perspectives. As a part of the discussions of the perspectives, this study will be therefore explained with the regional correlations between the architect Kim Han-seop's works and activity, influential politicians, strong enthusiasm of education, architectural characteristics of the main building of Chosun University, architecture schools and association in Kwangju. Then, it will be finalised that Kim Han-seop and the main building of Chosun University are directly and indirectly correlated and affected each other strongly.

• Journal of the Daesoon Academy of Sciences
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• v.34
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• pp.239-262
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• 2020

Reacting to Lu Jiu-yuan's teachings on "Wuji-Taiji," Zhu-Xi explicitly outlined his own viewpoints on the concept of "Taiji." Furthermore, he established a system of cosmological ontology based on them. Zhu-xi's main viewpoints and arguments on "Taiji" were fully understood and accepted by Lee Eon-jeok, who inherited and developed them even further. Lee Eon-jeok argued with Cho Han-bo, a thinker who contended against Lu Jiu-yuan (Son Sook-don) on the interpretation of "Wuji er Taiji" by deftly quoting Zhu-xi's point of view from Zhu-xi's standpoint. In modern times, Daesoon Thought has borrowed the concept of "Wuji" and "Taiji," and interpreted the original body of the "Dao" as "Wuji" to reveal a stationarity of the "Dao." This is interpreted as the specific creation of all things and the process of change, wherein Taiji represents the revealed activity of the "Dao." This development can be seen as an attempt by Daesoon Thought to clear away all suffering and enmity and open up a Later World of love and justice through an omnipotent Supreme God (Sangje) in times of desperate crisis of internal and external troubles.