• Archives of Pharmacal Research
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• 제25권5호
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• pp.643-646
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• 2002

The succinic semialdehyde dehydrogenase (SSADH) inhibitory component was isolated from the EtOAc fraction of Lactuca sativa through repeated column chromatography; then, it was identified as phytol, a diterpenoid, based on the interpretation of several spectral data. Incubation of SSADH with the phytol results in a time-dependent loss of enzymatic activity, suggesting that enzyme modification is irreversible. The inactivation followed pseudo-first-order kinetics with the second-rate order constant of $6.15{\times}10^{-2}mM^{-1}min^{-1}.$ Complete protection from inactivation was afforded by the coenzyme $NAD^{+}$, whereas substrate succinic semialdehyde failed to prevent the inactivation of the enzyme; therefore, it seems likely that phytol covalently binds at or near the active site of the enzyme. It is postulated that the phytol is able to elevate the neurotransmitter GABA levels in central nervous system through its inhibitory action on one of the GABA degradative enzymes, SSADH.

• 한국콘텐츠학회논문지
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• 제13권7호
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• pp.91-101
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• 2013

불확실성의 시대에 현대건축은 다양한 미디어의 발전으로 인해 표현 양상과 전개 및 방법론에 있어 과거에 비해 훨씬 자유로워지면서 건축의 표현 양상에도 많은 변화가 시도되고 있다. 특히 현상학이 대두되면서 건축공간에 현상학적 표현의 방법이 다각도로 진행되고 있으며 건축의 형태에서 벗어나 본질적이며 인간과 상호 소통하고 체험할 수 있는 공간에 대한 탐색이 활발히 진행되고 있다. 본 연구는 건축적 형태(Figure)와 공간(Space)을 지각하고 인식하게 되는 방법으로써의 현상학적 이해를 통해 기존의 물적 구조체로서의 건축에 대한 이해를 현상을 품은 콘텐츠의 주체로써 이해하여 다각적인 공간 디자인의 방법을 모색하고 적용하는데 있다. 건축의 표현양식에 있어서 현상적적 접근은 빛을 건축공간에 접목하여 발표한 건축들을 중심으로 살펴보았다.

• Journal of Communications and Networks
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• 제13권2호
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• pp.113-124
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• 2011

Electrocardiography (ECG) is a widely accepted approach for monitoring of cardiac activity and clinical diagnosis of heart diseases. Since cardiologists have been well-trained to accept 12-lead ECG information, a huge number of ECG systems are using such number of electrodes and placement configuration to facilitate fast interpretation. Our goal is to design a wireless ECG system which renders conventional 12-lead ECG information.We propose the three-pad ECG system (W3ECG). W3ECG furthers the pad design idea of the single-pad approach. Signals obtained from these three pads, plus their placement information, make it possible to synthesize conventional 12-lead ECG signals.We provide one example of pad placement and evaluate its performance by examining ECG data of four patients available from online database. Feasibility test of our selected pad placement positions show comparable results with respect to the EASI lead system. Experimental results also exhibit high correlations between synthesized and directly observed 12-lead signals (9 out of 12 cross-correlation coefficients higher than 0.75).

• 한국주거학회논문집
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• 제12권3호
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• pp.41-49
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• 2001

This study attempts to present a new interpretation of the Jeju province Waga, authorized as Jeju province Folklore, in the context of lifestyles of residents distinctive in the Jungji, Chatbang, and Gopang system. Study results uncovered that (1) only one Jungji, a traditional house kitchen, exists in one house boundary, in the form of detached building in the 4 units of Gaok (K-2 Gaok, K-3 Gaok, C-1 Gaok, and C-2 Gaok) (2) Chatbang had multifaced-functions; as a place for diet for mistress and children, a place for preparing meals for a mister who diet in the room, and as an auxiliary meal-preparation facility in time of domestic celebration day. (3) Gopang was mostly a place for grain storage, and K-3 Gaok has one unit, K-1 Gaok, C-1 Gaok, and C-2 Gaok had 2 units, and K-2 Gaok and H Gaok had 3 untis of Gopang. (4) Jungji and Chatbang were correlated for meal preparation and diet while activity-line of flow was divided each other. (5) Jungji and Gopang were located at the opposite edges of of each house, revealing no consideration of indoor activities. (6) The ratios of space of Jungji, Chatbang and Gopang out of the whole house space were, average 23% in the case of Jungji located in the inner house, and average 37% in the case of Jingji located in the detached building, average 14% larger in the case of detached Jungji system.

• 대한지역사회영양학회지
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• 제5권2호
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• pp.343-351
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• 2000

The Korean government enacted the National Health Promotion Act in January, 1995 and proclaimed its regulations and rules in September 1995, which became the basis of the national health policy. The health promotion programs consist of education for health, prevention of diseases, improvement of nutrition, and practice of healthy life style as defined in that Act. The Community Health Act was amended in 1995, which included implementing nutrition services in community health centers. The purpose of this report is to summerize the nutrition services conducted in 32 community health centers. the main nutritional activities were as follows : 1) nutritional guidance by counseling and education for pregnant or lactating women, infants, preschool children, and those with chronic diseases, 2) collection, analysis, and interpretation of data collected from the community, on background conditions and target population for the assessment of community needs, 3) evaluation of nutritional status of population in the community 4) nutritional guidance for mass feeding in different institution including schools and welfare institutions. In order to meet the government's expectations and desires, the community health centers have made continuous efforts to put nutritional activities into practice in the community. However, there are constraints, such as relative staff shortages, lack of funds, and information which hampers the nutritional activities.

• Natural Product Sciences
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• 제16권2호
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• pp.68-74
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• 2010

Phytochemical investigation on the ethyl acetate and n-butanol fractions of Moutan Cortex resulted in the isolation and characterization of a new monoterpene glycoside (3) and twenty known monoterpene glycosides (1, 2, 4-21). The structure of 3 was determined by spectroscopic data interpretation and physico-chemical properties. Compounds 1 and 8 presented a remarkable inhibitory activity against lipoxygenase-1 (LOX-1) with $IC_{50}$ values of 45.2 and $37.5\;{\mu}M$, respectively. Compounds 9, 10, 13, 18, 19, and 21 showed significant 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging effect with $IC_{50}$ values of 9.8, 25.5, 6.4, 15.2, 18.7, and $23.7\;{\mu}M$, respectively. Benzoylpaeoniflorin (8), which exhibited the highest inhibitory effect with an $IC_{50}$ value of $37.5{\pm}0.7{\mu}M$, was further analyzed the inhibition kinetics by Lineweaver-Burk plots. Results indicated that 8 is a non-competitive inhibitor, and the kinetic parameter values were estimated to be ($31.04\;{\mu}M$, Ki), ($0.29\;{\mu}M/min$, $V_m$), and ($48.50\;{\mu}M$, $K_m$).

• 한국진공학회:학술대회논문집
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• 한국진공학회 2000년도 제18회 학술발표회 논문개요집
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• pp.137-137
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• 2000

The surface collective modes of thin K films deposited on Al(111) have been investigated using frequency dependent photoyield measurements and momentum resolved inelastic electron scattering. Jellium based theoretical calculations have predicted a richer set of features in the thin films than for the surface of a semi-infinite solid because there are th interference between two interfaces (substrate-film and film-vacuum) and heavy damping on the substrate. The use of an optical probe and electron scattering has allowed us to draw a more complete picture of the dynamic screening in thin films. The number, dispersion, damping and optical activity of the collective modes of the thin films have been measured as a function of K film thickness. New overlayer-induced excitations are observed : At qII=0, they correspond to the antisymmetric slab mode and the multipole surface plasmon. At finite qII=0, these modes undergo a transition towards the K multipole and monopole surface plasmons. With increasing coverage, the overlayer excitations turn into the collective modes of semi-infinite K. For a consistent interpretation of photoyield and electron energy loss spectra it is crucial to account for the non-analytic dispersion of the overlayer modes at small parallel wave vectors and for the finite angular resolution of the detector. The observed dispersions confirm predictions based on the time-dependent density functional approach.

• 한국해양바이오학회지
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• 제5권4호
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• pp.46-50
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• 2011

Phytoplankton forms the base of sea ecosystems. Various environmental factors and anthropogenic pollution, primarily, affect the concentration and photosynthetic activity algal cells, and the changes in the phytoplankton photosynthesis influence other elements of aquatic ecosystems. The increase in anthropogenic pollution markedly damages natural aquatic ecosystems, particularly, in the coastal zones, where an intense blooming of microalgae occurs, including the release of highly dangerous ecotoxic substances of various chemical natures (red tides). In this study, we tried to apply as a parameter for the algal blooming prediction in the ocean from fluorescence values in the taken samples around Busan coastal area. F0 value was almost constant but Fv/Fm value showed the irregular pattern. We presume that these results are due to the changes of the ocean environment and climate. To predict or give early warning the algal blooming, we need to investigate the specific area or fixed area through real-time monitoring. Especially, algal blooming prediction or warning can be achieved via continuously monitoring and interpretation of fluorescence changes.

• 건축역사연구
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• 제27권6호
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• pp.41-48
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• 2018

For the proper preservation and utilisation of Regional Modern Heritage Buildings, it is necessary to study the history of local modern architecture based on a broad understanding of the region and also to architectural history. The aim of this study is expand the awareness and multi-faceted interpretation of modern architecture in Kwangju in the 1940's to 1950's, by exploring the origin of regional modern architecture from new perspectives. As a part of the discussions of the perspectives, this study will be therefore explained with the regional correlations between the architect Kim Han-seop's works and activity, influential politicians, strong enthusiasm of education, architectural characteristics of the main building of Chosun University, architecture schools and association in Kwangju. Then, it will be finalised that Kim Han-seop and the main building of Chosun University are directly and indirectly correlated and affected each other strongly.

• 대순사상논총
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• 제34집
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• pp.239-262
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• 2020

朱熹通过与陆九渊进行「无极太极」论辩, 明确了对「太极」概念的观点, 并以此为基础建构了自己宇宙本体论体系。朱熹对「太极」的主要观点和主张, 不仅被李彦迪完全理解和接受, 进一步被李彦迪继承和发明。李彦迪彻底站在朱熹的立场, 巧妙引用朱熹的观点, 与陆九渊 (孙叔暾) 相对立的曹汉辅围绕「无极而太极」的解释问题进行了论辩。到近代, 大巡思想借用无极与太极概念, 以「无极」来解释道之本体, 无极作为道之「定」的侧面, 具有本体层面上的含义 ; 以「太极」来解释万物之具体生成,变化的过程, 太极作为道之「动」的侧面, 具有作用层面上的含义。进一步, 在无极与太极概念的基础上, 大巡思想多设一个「九天应元雷声普化天尊上帝」的存在, 来发挥「掌管」和「主宰」无极与太极的作用。在当时内忧外患的时代背景下, 大巡思想试图以万能的存在——上帝, 消除一切痛苦和怨恨, 开辟充满真爱和正义的后天世界。