• Molecular & Cellular Toxicology
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• v.2 no.4
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• pp.223-228
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• 2006

Several plant-derived cannabinoids and endogenous ligands for cannabinoid receptors such as 2-arachidonyl-glycerol have been known to inhibit interleukin-2 (IL-2) expression. In the present study, we utilized arachidonylethanolamide (AEA), a putative endogenous ligand for cannabinoid receptors, to determine whether AEA modulated the expression of IL-2. AEA inhibited phorbol 12-myristate 13-acetate (PMA) plus ionomycin (Io)-induced IL-2 protein secretion and mRNA expression in EL-4 mouse T-cells as determined by ELISA and RT-PCR, respectively. To further characterize the inhibitory mechanism of AEA at the transcriptional level, we performed promoter study for IL-2 gene in PMA/Io-stimulated EL-4 cells. AEA decreased the transcriptional activity of the nuclear factor of activated T-cells (NF-AT) as well as the IL-2 promoter activity. These results suggest that AEA suppresses IL-2 expression and that the inhibition is mediated, at least in part, through the down-regulation of NF-AT.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.4
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• pp.1331-1336
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• 2015

Natural glycoproteins can induce apoptosis of tumor cells and exert anti-tumor activity by immunomodulatory functions, cytotoxic and anti-inflammation effects, and inhibition of endothelial growth factor. Given their prospects as novel agents, sources of natural antitumor glycoproteins have attracted attention and new research directions in glycoprotein biology are gradually shifting to the direction of cancer treatment and prevention of neoplastic disease. In this review, we summarize the latest findings with regard to the tumor suppressor signature of glycoproteins and underlying regulatory mechanisms.

• Journal of Educational Research in Mathematics
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• v.12 no.2
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• pp.265-274
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• 2002

The purpose of the paper is to provide the importance of matacognition as a factor to correct the errors generated by the intuition. For this, first of all, we examine not only the role of metacognition in mathematics education but also the errors generated by the intuition in the mathematical problem solving process. Next, we research the possibility of using metacognition as a factor to correct the errors in the mathematical problem solving process via both the related theories about the metacognition and an example. In particular, we are able to acknowledge the importance of the role of metacognition throughout the example in the process of the problem solving It is not difficult to conclude from the study that emphasis on problem solving will enhance the development of problem solving ability via not only the activity of metacognition but also intuitive thinking. For this, it is essential to provide an environment that the students can experience intuitive thinking and metacognitive activity in mathematics education .

• Journal of the Korean Home Economics Association
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• v.26 no.3
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• pp.153-169
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• 1988

This study aimed at investigating the socialization of householdwork to the difference of life style pattern of housewives. For the purpose, questionnaires were administrated to the housewives in Seoul and to analyse of the date, factor analysis F-test, t-test and path analysis were used. The results can be summarized as follows ; 1. By utilizing factor analysis, the life style patterns of housewives were classified into 7 types, they were named, self-improvement type, social activity type, modernistic type, sound and thrifty type, variety-seeking type, passive stability-seeking type, the traditional and conservative type. And the patterns of life style differed significantly according to all of the demographic variables except family type. 2. The level of socialization of householdwork was not reaching the medium, and the mean was 19.45. 3. The socialization of householdwork were influenced indirectly by the age, educational level, income level, family type and social activity type, variety seeking type, traditional and conservative type of the life style pattern. And directly, the age and educational level influenced the socialization of householdwork.

• Journal of the Korean Home Economics Association
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• v.41 no.6
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• pp.105-117
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• 2003

This study was intended to investigate specific plan to enhance the adolescents consumers' environment-friendly consumption behavior in their consumption. For this purpose, a questionnaire was conducted among middle and high school students. As a result, the following findings were obtained: The related items in the questionnaire were categorized into factors in an attempt to investigate consumers' environment-friendly consumption. Factor I was coded as active recycling and the use of refilled products and Factor Ⅱ was coded as the behavior of active savings. Adolescents consumers with more experiences in environmental activity showed the higher level of behavior of environment-friendly consumption, and female adolescents consumer did so than male adolescents consumer And adolescents consumers showed the higher level of practical behavior of environment-friendly consumption in case of data and document arrangement than in case of cleaning, and in case of voluntary social service than in case of only cleaning.

• YAKHAK HOEJI
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• v.57 no.6
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• pp.426-431
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• 2013

In our previous studies, 6-hydroxy-7-methoxychroman-2-carboxylic acid N-phenylamide (KL-1156) was identified as a good inhibitor of nuclear factor-${\kappa}B$ (NF-${\kappa}B$) activation. In continuation of our study, we describe the structure-activity relationship of chroman derivatives containing N-arylalkyl groups and their NF-${\kappa}B$ inhibitory activities. In addition, inhibitory effects of cell proliferation are evaluated against human cancer cell lines (NCI-H23 and PC-3). The most active compounds 3i and 3j contained diphenylethyl and diphenylpropyl side chain on amide nitrogen.

• Journal of the Korea Safety Management & Science
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• v.14 no.4
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• pp.291-301
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• 2012

Quality management activities are an important factor that they could be regarded as a most significant drive to prompt growth of a corporation. From this research as core strategy of the enterprise single ppm wants to emphasize the importance of the quality management activity. The Empirical results are summarized as follows, for successful Single PPM, leadership and corporate culture should be based on. As Single PPM activities factor, Customer Management significantly affects Single PPM Performance. Therefore, to the success of quality management activities, internal corporate leadership and corporate culture must be formed. And for customer management, should take advantage of a variety of the company's internal and external information strategically.

• The Korean Journal of Food And Nutrition
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• v.34 no.4
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• pp.415-422
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• 2021

This study assessed the preparation and quality characteristics of cookies prepared from Taraxacum coreamm powder (TCP) (0, 2, 4, 6, 8%) substituting wheat flour. The pH of the cookie dough significantly decreased with increasing TCP. However the density of the cookie dough was not significantly different among the test groups. The baking loss rate of the groups with TCP was slightly lower, whereas the moisture content was higher than the control group. The spread factor of the cookies decreased significantly with increasing TCP. The hardness of the cookies increased as TCP increased. In Hunter's color value, the L and a value of the cookies decreased with increasing TCP, while the b value increased. The DPPH radical scavenging activity of the cookies significantly increased with increasing TCP. Based on the above results, this study suggested that TCP can be a good ingredient to increase the functionality of cookies.

• Analytical Science and Technology
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• v.19 no.3
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• pp.226-238
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• 2006

The electroplating of the Ag ions from aqueous solution on activated porous carbons was investigated over a wide range of plating time. The adsorption capacities of Ag metallic carbons were associated with their internal porosity and were related to physical properties such as surface area and pore size distribution. And, surface morphologies and quantitative analysis for the metal supported carbons are investigated by scanning electron microscopy (SEM) and energy disperse X-ray (EDX) measurements to explain the changes in adsorption properties. It is considered that the pH is an very important factor at the reason of water pollutant with increasing acidity in industrial field. The results of ICP-AES analysis showed that the residual concentration of Ag ions decreased with an increasing electroplating time. The metallic Ag-activated porous carbons electroplated showed microbicidal effects and strong antibacterial activity against six kinds of strains that were used. Finally, we confirmed that the presence of the electrolytic plated Ag-activated porous carbons is a determining factor in the HCl removal by chemical reaction, clarifying the surface chemical behavior.

• Nuclear Engineering and Technology
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• v.55 no.11
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• pp.3935-3939
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• 2023

The paper presents the results of a study of radioactive noble gases and from decay products in the atmosphere of the reactor hall of the research nuclear reactor IVV-2M. The distribution of short-lived ⁸⁸Rb and ¹³⁸Cs activity by sizes of aerosol particles was measured in the range of 0.5-1000 nm. It is shown that radioactive aerosols are characterized by three main modes with AMTD 2-3 nm, 7-15 nm and 400 nm. About 70% of aerosol activity is due to ⁸⁸Rb. The equilibrium factor between ⁸⁸Kr and ⁸⁸Rb is 0.2 ± 0.1. The total concentration of aerosols particles was measured using an aerosol diffusion spectrometer. The value of unattached fraction of radioactive aerosols in the atmosphere of reactor hall IVV2M was f = 0.15-0.25 at the average total aerosol particles concentration from 20,000 cm³ to 53,000 cm³.