• Journal of Nutrition and Health
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• v.28 no.9
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• pp.893-903
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• 1995

This study was attempted to estimate seasonal variations of physical activity level, energy balance & body composition of 38 rural women, aged 31 to 67yrs in three seasons ; farming season(June), harvesting season(October), nonfarming season(February) Energy intake, energy expenditure and body composition were assessed using questionnaire, daily activity diary & bioelectrical impedance. The type of activities & the period of the spent on each activity were changed significantly with the seasons. Daily mean duration(min) of farming activity was significantly higher in June & October than in February(p<0.005) & daily mean energy expenditure for farming activity was significantly high in June & low inFebruary (p<0.005). Daily mean energy expenditure was 2892.9㎉ in June, 2487.4㎉ in October and 2130.9㎉ in February and changed significantly in three seasons(p<0.005). Daily mean energy intake was significantly higher in June(=1950.3㎉) & October (=1946.9㎉) than in February(=1423.3㎉)(p<0.005). According to RDA for koreans, the level of physical activity fell into exceptional activity category in June, heavy in October, moderate in February. Mean energy balance was negative in all seasons ; 0.682 in June, 0.812 in October and 0.698 in February. In three seasons mean body weight, mean obesity rate and mean body mass index(BMI) were not changed significantly. But there were significant seasonal variations in body fat(%) & lean body mass(LBM)(%). The mean percentage of body fat(%) was within normal range(24.44-24.79%) & the mean percentage of lean body mass(LBM)(%) representing long term physical activity was significantly higher in June(75.56%) & October(75.21%) & October (75.21%) than in February(72.75%)(p<0.05).

• Journal of Korea Society of Industrial Information Systems
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• v.23 no.3
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• pp.49-57
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• 2018

In a previous article, for analyzing a stochastic activity network, Cho proposed a method for estimating the moments (mean, variance, skewness, kurtosis) of the project completion time under the assumption that the durations of activities are independently and normally distributed. Developed in the present article is a method for estimating those moments for stochastic activity networks which allow any type of distributions for activity durations. The proposed method uses the moment matching approach to discretize the distribution function of activity duration, and then a discrete inverse-transform method to determine activity durations to be used for calculating the project completion time. The proposed method can be easily applied to large-sized activity networks, and computationally more efficient than Monte Carlo simulation, and its accuracy is comparable to that of Monte Carlo simulation.

• Food Science of Animal Resources
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• v.37 no.5
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• pp.646-653
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• 2017

Alcalase hydrolysis of liquid egg white was used to produce 5-hydroxytryptophan (HTP) under various conditions and investigate the sleep-potentiating activity of liquid egg white hydrolysate (LEH) on pentobarbital-induced sleep. Alcalase hydrolysis yielded the highest content of 5-HTP ($13.50{\mu}g/mL$), while neutrase hydrolysis showed the lowest 5-HTP content ($5.23{\mu}g/mL$). The liquid egg white to water ratio (1:1) was optimal for the production of 5-HTP with high amino-nitrogen (A-N) content and degree of hydrolysis. The 5-HTP, amino-nitrogen, and degree of hydrolysis increased until 24 h of hydrolysis and slightly increased thereafter during hydrolysis with 2% and 5% enzyme addition. 5-HTP administration at doses of 6 and 9 mg/kg significantly increased sleep duration and decreased sleep latency time compared to that in the control (p<0.05). LEH (150 mg/mouse), which was equivalent to 5-HTP at 6 mg/kg, significantly decreased sleep latency time and increased sleep duration time compared to that in the control (p<0.05). Oral administration of LEH showed sleep-potentiating effects because of 5-HTP. The sleep-potentiating activity of LEH may have occurred through 5-HTP in our pentobarbital-induced sleep model. LEH may be a valuable alternative to sleep enhancement and may be used as a sleep-potentiating agent.

• Biomolecules & Therapeutics
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• v.23 no.5
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• pp.479-485
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• 2015

This study was performed to investigate the sedative-hypnotic activity of ${\gamma}$-aminobutyric acid (GABA)-enriched fermented marine organisms (FMO), including sea tangle (FST) and oyster (FO) by Lactobacillus brevis BJ20 (L. brevis BJ20). FST and FO were tested for their binding activity of the $GABA_A$-benzodiazepine and 5-$HT_{2C}$ receptors, which are well-known molecular targets for sleep aids. We also measured the sleep latency and sleep duration during pentobarbital-induced sleep in mice after oral administration of FST and FO. In $GABA_A$ and 5-$HT_{2C}$ receptor binding assays, FST displayed an effective concentration-dependent binding affinity to $GABA_A$ receptor, similar to the binding affinity to 5-$HT_{2C}$ receptor. FO exhibited higher affinity to 5-$HT_{2C}$ receptor, compared with the $GABA_A$ receptor. The oral administration of FST and FO produced a dose-dependent decrease in sleep latency and increase in sleep duration in pentobarbital-induced hypnosis. The data demonstrate that FST and FO possess sedativehypnotic activity possibly by modulating $GABA_A$ and 5-$HT_{2C}$ receptors. We propose that FST and FO might be effective agents for treatment of insomnia.

• Archives of Pharmacal Research
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• v.26 no.10
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• pp.840-845
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• 2003

Temperature change is one of the major environmental factors that influence the human skin. However, the relationship between temperature and melanogenesis has received little attention. In the present study, we investigated the effects of temperature change on melanogenesis in a mouse melanocyte cell line (Mel-Ab), and primary cultured human melanocytes. We found that Mel-Ab cells cultured at low temperatures (31 and 34$^{\circ}C$) produce less melanin than cells at 37$^{\circ}C$. These results were confirmed by experiments upon human melanocytes, demonstrating that the hypopigmenting effect of low temperatures is not cell type dependent. The observed melanin production was found to be accompanied by tyrosinase activity at each temperature, indicating that tyrosinase activity is regulated by temperature. We further examined whether the incubation period at low temperatures plays an important role in the regulation of melanogenesis. Short exposures to 27$^{\circ}C$ for 1 h or 3 h did not affect tyrosinase activity or melanin synthesis, whereas long exposures to 31$^{\circ}C$ for 2 days or 6 days significantly reduced tyrosinase activity and melanin synthesis in a duration-dependent manner. Our results suggest that exposure to low temperature and the duration of this exposure are important regulators of melanogenesis.

• The Korean Journal of Rehabilitation Nursing
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• v.2 no.2
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• pp.193-205
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• 1999

This study was carried out to identify the important risk factors for reduced bone mass of postmenopausal RA patients and to develop discriminant function which can classify postmenopausal RA patients with either reduced or normal bone mass. Through the literature review, individual characteristics such as age, body weight, height, age of menarche, duration of menopause, gravity, parity, and breast feeding period and factors of life style such as milk consumption exercise habit, alcohol intake, cigarette smoking, coffee consumpt ion , disease activity, corticosteroid therapy were identified as influencing factors of reduced bone mass in RA patients Sixty eight postmenopausal women with rheumatoid arthritis aged between 42 and 76 were selected among those who checked bone mineral density in lumbar spine and femur from october, 1998 to Apr il, 1999 at Dong-a university hospital in Pusan. Assessment of disease activity, duration of disease and corticosteroid therapy were made by the same rheumatologist and included Ritchie articular index, erythrocyte sedimentation rate, and C-reactive protein on measuring bone mineral density. Cumulative steroid dosage was calculated from the daily dosage multiplied by t h e number of days received. The information of other risk factor including health assessment score, individual characteristics and life style factors were collected by questionnaire. Bone mineral density(BMD) was measured using DXA at lumbar spine and femoral Ward's triangle. Discriminant function(regression equation) was developed for estimating the likelihood of the presence or absence of reduced bone mass. The results are as follows: Among the subjects, thirteen(19.1%) exhibited osteoporosis in lumbar spine and twenty four(35.3%) exhibited osteoporosis in femoral Ward's triangle. For lumbar spine, the variables significant were age, body weight, health assessment score, while for femoral Ward's triangle, age, body weight, duration of disease. But disease activity and corticosteroid therapy were not signigicant to distinguish reduced bone mass from normal bone mass. When the discriminant function was evaluated by comparing the observed out come with predicted out come, the discriminant function correctly classified 85.4% of patients with reduce bone mass and 63.0% of patients with normal bone mass in the lumbar spine and 100% of patients with reduced bone mass and 9.1% of patients with normal bone mass in the femoral Ward's triangle. In summary, we found that osteoporosis in postmenopausal women with RA is more evident at the femur than the lumbar spine. Also the important discriminant factors of reduced bone mass postmenopausal women with RA were age, body weight , duration of disease and health disability. In nursing situation, the efforts to improve of functional capacity of postmenopausal women with rheumatoid arthritis should be considered to prevent osteoporosis and fractures. Also we recommend those postmenopausal women with RA who are classified as a group of the reduced bone mass in the discriminant function should examine the bone mineral density to further examine the usefulness of this discriminant function.

• International journal of advanced smart convergence
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• v.8 no.2
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• pp.68-76
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• 2019

In this study, we propose a squid jeotgal, Korean fermented seafood, supplement with different soy isoflavones supplements, followed by fermentation for different time intervals at $4^{\circ}C$ to increase the antioxidant activity and improve the food value. In the first month, fermented jeotgals with at lowconcentration ($2mg\;g^{-1}$) of added soy isoflavones showed a significant increase in the activity of up to 55%, whereas, at high concentration ($10mg\;g^{-1}$), the activity almost doubled compared to that of the sample without isoflavones. Moreover, the squid enriched with isoflavones also exhibited significantly decreased total volatile base nitrogen, thiobarbituric acid reactive substances, and biogenic amines, indicative of higher inhibition of the formation of these substances. The changes in the microbial profile were also evaluated. This use of soy isoflavanones as an additive could aid in improving the nutritional value of fermented seafood to reduce the incidence of age-related and chronic disorders.

• International conference on construction engineering and project management
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• 2020.12a
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• pp.41-49
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• 2020

Concurrent construction offers considerable improvement for shorten the project duration of its production process. Therefore, standardized concurrent construction is widely applied in building construction projects. However, resources planning for standardized concurrent construction project is manually developed by construction manager. This practice is not effective since it is time-consuming and error-prone for managers to identify all project-specific information, distinguish different activity-resource types, interpret these types and analyze how they affect resource allocated on an ad hoc basis. Therefore, this research investigates the opportunity for leveraging activity modeling to enable automated resource planning for standardized concurrent construction during project development, with identifying the characteristics of construction activities under standardized concurrent planning and determining the activity-resources types that affects resource planning. Both will function as a basis for modeling these construction activities in a computer-interpretable manner and for automation in resource planning.

• The Transactions of the Korea Information Processing Society
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• v.6 no.11
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• pp.3131-3139
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• 1999

Satisfying the rigid timing requirements of various real-time activities in real-time systems often requires some special methods to tune the systems run-time behaviors. Unbounded blocking can be caused when a high priority activity cannot preempt a low priority activity. In such situation, it is said that a priority inversion has occurred. The priority inversion is one of the problems which may prevent threads from meeting the deadlines in the real-time systems. It is difficult to remove such priority inversion problems in the kernel at the same time to bound the worst case blocking time for the threads. A thread is a piece of executable code which has access to data and stack. In this paper, a new real-time systems. It is difficult to remove such priority inversion problems in the kernel at the same time to bound the worst case blocking time for the threads. A threads is a piece of executable code which has access to data and stack. In this paper, a new real-time server model, which minimizes the duration of priority inversion, is proposed to reduce the priority inversion problem. The proposed server model provides a framework for building a better server structure, which can not only minimize the duration of the priority inversion, but also reduce the deadline miss ratio of higher priority threads.

• The Journal of Korean Academic Society of Nursing Education
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• v.19 no.4
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• pp.542-548
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• 2013

Purpose: This study was conducted to explore clinical practice performance according to type of practice in students in pediatric nursing and the relationship with satisfaction of clinical practice. Methods: The subjects consisted of 531 nursing students (307 at a pediatric ward and 224 at a nursery) from 5 colleges of nursing. Data collected from March to June 2012 were analyzed using descriptive statistics, t-test, AVONA and Pearson correlation coefficients. Results: Clinical practice performance on direct nursing activity was significantly different according to the course on pediatric nursing, grade point average, and satisfaction of nursing major. Observation practice was different according to type of college, the course on pediatric nursing, grade point average, duration of practice and clinical educator in the pediatric ward. In the nursery, direct nursing activity was significantly different according to the type of college, the course on pediatric nursing, hospital type, and duration of practice. Observation practice was different according to type of college, satisfaction of a nursing major, and the clinical educator. In addition, significant correlations were found between clinical practice performance and satisfaction of clinical practice. Conclusion: Our research can assist effective pediatric nursing practice planning for nursing students.