• 대한화학회지
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• 제60권1호
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• pp.59-68
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• 2016

최근 과학교육에서 강조되고 있는 과학적 소양의 함양은 과학 지식이 형성되는 일련의 탐구 과정을 경험하고 이해함으로써 향상될 수 있다. 이러한 관점에서 미국연구회(NRC)의 차세대과학기준(NGSS)은 학생들의 과학 탐구 과정 경험과 이해를 돕기 위하여 8가지 과학 실천(8 Practices of Science)을 제안하였고, 8가지 과학 실천 각각에 대하여 학년 군별 세부성취 목표를 제시하고 있다. 본 연구에서는 2009 개정 교육과정에 따른 고등학교 화학II교과서 4종에 포함된 탐구 활동을 8가지 과학 실천과 9-12학년군 세부 성취 목표를 기준으로 분석하였다. 4종의 화학II교과서에 포함된 탐구 활동은 총 173개 이고 분석된 과학 실천은 총 678개 이었다. 4종 화학II교과서의 탐구 활동에 포함된 과학 실천은 ‘자료 분석하고 해석하기’가 가장 많았고, ‘증거에 입각하여 논의하기’, ‘정보를 얻고 평가하고 의사소통하기’등은 상대적으로 그 기회가 부족하였으며, ‘질문하고 문제 규정하기’와 ‘모형 개발하고 사용하기’는 거의 포함되어 있지 않았다.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.139.2-140
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• 2003

Tannin-rich fruit of Cornus officinalis Sieb. et Zucc has been used as an ingredient in several prescriptions of Oriental medicine. Cornis fructus was extracted by successive extraction. Cornis fructus extracts were investigated for antimicrobial and antioxidative activities. Antimicrobial effects used disk diffusion method. All extracts were examined against Streptococcus mutans. (omitted)

• Journal of Forest and Environmental Science
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• 제26권3호
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• pp.171-179
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• 2010

Effect of chromium (Cr) stress on antioxidant enzyme activities and malondialdehyde (MDA) content were investigated in leaves and roots of mangrove (italic (L.) Druce) seedlings. Cr toxicity effects were also assessed on young seedlings. The seedlings were grown in green house condition for three months in nutrient solution with 0, 0.5, 1, 1.5, 2, 2.5, and 3 mg $L^{-1}$ $CrCl_3$. This study showed that Cr led to the change of antioxidant enzymes such as superoxide dismutase (SOD), peroxidase (POD) and catalase (CAT) and activities at different concentrations. The activity of antioxidant enzymes in leaves of K. candel seedlings indicates that enzymes engaged in antioxidant defense in certain level especially in low concentration of Cr treatments. The activities of SOD and POD were activated by Cr in the root level, while CAT activity was inhibited. CAT activity decreased in response to high concentrations of Cr. In the present study indicated that SOD in root was active in scavenging the superoxide produced by Cr. Both in roots and leaves, an increase in malondialdehyde (MDA) content was observed with increase in metal concentration and exposure periods. Our finding indicated that the high concentration of excessive Cr supply may interfere with several metabolic processes of seedlings, causing toxicity to plants as exhibited by chlorosis, necrosis, photosynthetic impairing and finally, plant death.

• 과학교육연구지
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• 제35권1호
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• pp.68-79
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• 2011

이 연구에서는 형식적 사고를 요구하는 '기체 분자운동'의 개념 이해에 형식적 조작기로의 인지가속을 목적으로 하는 '생각하는 과학' 활동을 사전에 적용했을 때 어떠한 효과가 있는지 알아보았으며 이 활동에 대한 학생들의 인식을 조사하였다. 교과서 내용 분석을 통하여, 기체 분자 운동의 개념 이해에 필요한 논리적 요소로 변인, 비례, 보상, 형식적 모형 등의 4가지 논리를 추출하였다. 실험 집단 학생들에게 4가지 논리와 관련된 9개의 '생각하는 과학' 활동을 처치한 후에 기체 분자 운동의 수업을 실시하고, 기체 분자 운동의 개념 이해에 대한 성취도 평가를 하였다. 기체 분자 운동 개념에 대한 실험 집단과 통제 집단간의 성취도는 t-검증 결과 유의미한 차이가 없었다. 성 별 분석에서는 사전 인지 수준을 공변인으로 한 공변량 분석 결과 실험 집단의 여학생이 유의미하게 성취도가 향상된 것으로 나타났다. 과학 성취도 평가의 논리 별 정답률에서는 변인 통제, 보상, 형식적 모형논리의 정답률이 통제 집단에 비해 높게 나타났으나 비례 논리는 거의 비슷하게 나타났다. 실험 집단의 '생각하는 과학' 활동에 대한 인식 조사 결과, 활동에 대한 인식이 긍정적일수록 성취도가 높게 나타났으며 과학적 사고력과 태도 영역이 기체 분자 운동의 성취도 사이에 상관관계가 있었다. 특히 구체적 조작기 후기(2B)의 학생들이 가장 긍정적 인식을 가지고 있었으며 성취도도 높았다. 학생들은 교과서에 나와 있지 않는 실험 소재를 다루게 되어 흥미로웠으며 실험 후 토론 시간을 가지면서 연구자가 된 듯한 느낌을 갖게 되어 '생각하는 과학' 활동을 통해 자신의 과학적 사고력이 향상된 것 같다고 답변하였다.

• 정보교육학회논문지
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• 제20권1호
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• pp.93-100
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• 2016

언플러그드 컴퓨터과학 활동은 카드, 실, 크래용 등 주변의 물건들을 사용하는 놀이와 퍼즐을 통하여 컴퓨터과학에 대하여 학습하는 활동의 모음이다. 기존의 언플러그드 활동은 알고리즘을 소개하고 실생활에 적용하는 것에 편중되어 문제 해결을 위하여 알고리즘을 적용하기 전에 이루어져야 할 자료의 표현 방법에 대한 활동은 상대적으로 부족한 실정이다. 본 연구에서는 초등학생들에게 그래프 이론의 기본 개념과 실생활에 적용할 수 있는 그래프 알고리즘을 소개하는 언플러그드 수업을 설계하고 수업을 실시한 후에 설문조사를 통하여 수준의 적절성과 수업 효과에 대하여 평가하였다. 설문 응답을 분석한 결과 모든 응답자가 본 연구에서 제시한 수업 내용이 초등학생에게 적합하다고 응답하였고 수업의 효과와 적절성에 대하여 긍정적인 응답을 보였다.

• Journal of Periodontal and Implant Science
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• 제30권1호
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• pp.27-39
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• 2000

To evaluate the effects of Dexamethasone(Dex), Platelet derived growth factor-BB(PDGF) and combination of Dex and PDGF(DP) on the growth and differentiation of MC3T3-E1 cells, Dex($10^{-7}\;M$) and PDGF(10 ng/ml) in experimental group were added to the cells at the days 5, 10, 15, 20, 25 and examined for cell proliferation activities, DNA synthesis activities, ALP activities and bone nodule formation. The results were as follows : 1. In Dex group, cell proliferation, DNA synthesis and ALP activities were lower until 15 days when compared to the control group. Bone nodules formation were shown at 10 days. 2. In PDGF group, cell proliferation and DNA synthesis activities were higher until 15 days and ALP activities were lower when compared to the control and Dex groups. Bone nodules formation were shown at 20 days. 3. In DP group, cell proliferation and DNA synthesis activities of PDGF were suppressed by Dex and synergistic effects of combination of Dex and PDGF on ALP activities were shown at days 5 when compared to control and Dex groups. Bone nodules formation activities of Dex were suppressed by PDGF.

• Current Research on Agriculture and Life Sciences
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• 제31권3호
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• pp.165-169
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• 2013

Rutin is one of the major flavonoids found in buckwheat (Fagopyrum esculentum Moench). While rutin is already known to exhibit anti-oxidative, anti-inflammatory, and anti-carcinogenic activities. However, the health beneficial function of rutin metabolites is not well understood. In DPPH radical scavenging assays, the present study found that 3,4-dihydroxyphenyl acetic acid had the highest total anti-oxidant activity, followed by 3,4-dihydroxyphenylacetic acid, rutin, homovanillic acid, and 3-hydroxyphenyl acetic acid. Further, 3,4-dihydroxyphenylacetic acid strongly reduced LPS-induced IL-6 production in RAW 264.7 cells, compared with other metabolites. Therefore, these results suggest that rutin metabolites have potential to be utilized as food ingredients with anti-oxidant and anti-inflammatory activities.

• 한국초등과학교육학회지:초등과학교육
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• 제36권4호
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• pp.316-330
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• 2017

The purpose of this study was to develop the ESD program related to creative-experience activity, and to examine the effect of its application. The program was composed of 13 sessions for fifth-grade class in elementary school, including all of the environmental, economic, and social aspects of ESD. This program was connected to the domains of creative hands-on activities, that is, career activities, club activities, self-regulated activities and voluntary service activities. The results was as follows. First, the experimental group to undergo the ESD program related to creative-experience activity did not show significant differences in environmental literacy compared to the control group, but it is proven that this program contributed to the improvement of learners' environmental emotion, skill, and participation. Second, the experimental group did not show significant differences in scientific attitude compared to the control group, but it was considered to affect the elementary students' criticism, self-esteem, and patience in positive and effective manner. In conclusion, more ESD program that cultivate elementary school students' environmental literacy need to be developed continuously, and more intensive research should be conducted to earn better understanding of ESD.

• ALGAE
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• 제29권3호
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• pp.237-247
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• 2014

Polysaccharides prepared from marine algae sometimes contain contaminants such as polyphenols and endotoxins that may mislead their bona fide biological activities. In this study, we examined bioactive contaminants in commercially available fucoindan from Fucus vesiculosus, along with ascophyllan and fucoidan from Ascophyllum nodosum. F. vesiculosus fucoidan inhibited the growth of Vibrio alginolyticus in a concentration-dependent manner ($0-1,000{\mu}g\;mL^{-1}$). However, the antibacterial activity of the fucoidan significantly reduced after methanol-extraction, and the methanol-extract showed a potent antibacterial activity. The extract also showed cytotoxicity to RAW264.7 and U937 cells, and induced apoptotic nuclear morphological changes in U937 cells. These results suggest that the antibacterial activity of the fucoidan is partly due to the methanol-extractable contaminants that can also contribute to the cytotoxicity on RAW264.7 and U937 cells. On the other hand, the activities to induce secretion of nitric oxide and tumor necrosis factor-${\alpha}$ from RAW264.7 cells were observed in the fucoidan even after methanol extraction, and the extract had no such activities. Our observations suggest that commercially available fucoidan should be purified prior to biochemical use.

• 한류연구
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• 제2권1호
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• pp.27-31
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• 2023

The purpose of this paper is to study the relationship between Art management and Cultural activities in China from the K-wave case. Research design, data, and methodology: This study used the method of the cases study survey, with the K-wave case in as the survey objects, 3 valid survey sample case were collected in this paper. Results: The two dimensions of art management and cultural activities differently influences from the K-wave, and the influence of availability on customer satisfaction is not significant. Conclusion: The results of this study will provide useful reference for the Art management and Cultural activities in China from the K-wave case. And improve the development of art management and cultural activities in China by improving the K-wave of service quality. Art management can shape urban commercial space in a beneficial way, create a good consumption atmosphere, and enhance the attractiveness and competitiveness of the city. The introduction of art elements into urban commercial space can create a strong cultural atmosphere, so that the city presents a smart look. Art management has a positive impact on K-Wave production and operation activities, which can promote the shaping of art commercial space, the promotion of urban cultural atmosphere.