• 한국통신학회논문지
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• 제39B권11호
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• pp.779-789
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• 2014

주파수 공유대역에서 가용 주파수 자원을 인지하여 효과적으로 공유하고 활용하기 위해서 데이터베이스 접속을 통한 무선환경 인지 기술과 광대역 스펙트럼 센싱을 통한 무선환경 인지 기술 개발이 필요하다. 본 논문에서는 IETF (Internet Engineering Task Force) PAWS (Protocol to Access White Space database) 표준 프로토콜 기반으로 개발한 TVWS (TV White Space) 데이터베이스 접속 프로토콜 구현 기술을 제시하고, TVWS에 적합한 MWC (Modulated Wideband Converter) 구조를 이용한 광대역 압축 스펙트럼 센싱 기술을 제안한다. 제안된 TVWS 데이터베이스 접속 프로토콜 구현 기술은 TVBD (TV Band Device)와 TVWS 데이터베이스에 탑재되어 실환경 테스트를 통해 안정적으로 동작함을 보인다. 본 연구에서 제안된 광대역 압축 스펙트럼 센싱 방식은 잡음 분산 추정 오차에 무관하게 일정 수준의 오경보 확률을 유지할 뿐만 아니라 95% 이상의 높은 검출 성능을 보인다. 또한, 본 논문에서는 미국 FCC와 유럽 ETSI에서 최근 마련한 TVWS 데이터베이스 정책을 분석하고, IETF에서 현재 마련 중인 화이트 스페이스 데이터베이스 접속 프로토콜에 관해 기술한다.

• 한국재료학회지
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• 제4권3호
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• pp.301-311
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• 1994

Co/Si계에서 고상확산에 의하여 비정질상이 생성되는지의 여부를 유효구동력 개념을 이용하여 예측하였으며 유효생성열 개념 및 PDF모델로부터 결정상의 생성과 상전이를 예측하였다. 한편, DSC와 XRD를 이용하여 Co/Si다층박막에서의 비정질상의 생성여부와 결정상의 생성 및 상전이를 확인하여 모델로부터 예측한 결과와 비교하였다. Co/si계에서는 비정질상이 성장하지 않았으며 이는 유효구동력 개념으로부터 예측된 결과와 일치하였다. Co/Si계에서 생성되는 최초의 결정상은 CoSi였으며 유효생성열과 PDF모델로부터 예측된 최초의 결정상은 각각 $CO_2Si$와 CoSi였다. 따라서 Co/Si계에서 생성되는 최초의 결정상은 구조적인 요소를 고려해 PDF모델의 예측결과와 잘 일치하였다. 증착당시 Co와 Si의 조성비가 2대 1일경우와 1대 2일 경우의 상전이는 각각 $CoSi \to Co_2Si$와 $CoSi \to Co_2Si \to CoSi \to CoSi_2$의 초기단계의 생성기구는 각각 핵생성이 율속이었으며, 이들의 생성에 필요한 활성화에너지는 각각 1.71, 2.34, 2.79eV이었다.

• 대한약리학회지
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• 제32권2호
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• pp.189-199
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• 1996

Myocardial ${\alpha}_1-adrenoceptors$ have been shown to mediate a biphaslc inotropic response that was characterized by a transient decline followed by a sustained increasing phase in guinea pig ventricular muscle. Recently one group reported that an ${\alpha}_1-adrenoceptors-induced$ intracellular $Na^+$ decrease is linked to fast $Na^+$ channel inhibition and another group reported that it is linked to $Na^+$-$K^+$ pump activation by ${\alpha}_{1b}-adrenoceptors$. But until now, its mechanism is not clear. Therefore, to see whether the $Na^+$channel or $Na^+-K^+$ pump is related to a decrease in intracellular $Na^+$ activity and/or the negative inotropic response, and which ${\alpha}_1-adrenoceptor$ subtype was involved in the decrease in intracellular $Na^+$activity by phenylephrine, we used conventional and sodium selective microelectrodes, and tension transducer to determine the effects of ${\alpha}_1-adrenergic$ stimulation on membrane potential, intracellular $Na^+$ activity, and twitch force in guinea pig ventricular muscles. $10^{-5}$ M Phenylephrine produced a slight hyperpolarization of the diastolic membrane potential, a decrease or increase in $a_N^i_a$, and a biphasic inotropic response. The negative inotropic response accompanied by a decrease in intracellular $Na^+$activity, whereas in muscles showing a remarkable positive inotropic response without initial negative inotropic effect was accompanied by an increase in intracellular $Na^+$ activity. The decrease in intracellular $Na^+$ activity was apparently inhibited by WB4101, an antagonist of the ${\alpha}_{1a}-adrenoceptors$. The decrease in intracellular $Na^+$ activity caused by phenylephrine was not abolished or reduced by a block of the fast $Na^+$ channels. $V_{max}$ also was not affected by phenylephrine. Phenylephrine produced an increase in intracellular $Na^+$ activity in the presence of a high concentration of extracellular $Ca^{2+}$ (in quiescent muscle) or phorbol dibutyrate, a protein kinase C activator(in beating muscle). These suggest that the ${\alpha}_{1a}-adrenoceptors-mediated$ decrease in intracellular $Na^+$ activity may be related to the protein kinase C.

• 대한수의학회지
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• 제38권1호
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• pp.29-42
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• 1998

$Mg^{2+}$ is one of the most abundant divalent cations in mammalian body(0.2~1.0mM) and the important physiological roles are : first, the cofactor of many enzyme activities, second, the regulator of glycolysis and DNA synthesis, third, the important role of bioenergetics by regulating of phosphorylation, fourth, the influence of cardiac metabolism and function. In this work we have investigated the regulation of the $Mg^{2+}$ induced by ${\alpha}_1-adrenoceptor$ stimulation in perfused guinea pig hearts and isolated myocytes. The $Mg^{2+}$ content of the perfusate or the supernatant was measured by atomic absorbance spectrophotometry. The elimination of $Mg^{2+}$ in the medium increased the force of contraction of right ventricular papillary muscles, and the left ventricular pressure. Phenylephrine also enhanced the force of contraction in the presence of $Mg^{2+}-free$ medium. ${\alpha}_1-Agonists$ such as phenylephrine and methoxamine were found to induce $Mg^{2+}$ efflux in both perfused hearts and myocytes. These effects were blocked by prazosin, an ${\alpha}_1-adrenoceptor$ antagonist. The $Mg^{2+}$ influx could also be induced by phenylephrine and R59022, a diacylglycerol kinase inhibitor. In the presence of protein kinase C(PKC) inhibitors, phenylephrine produced an increase in $Mg^{2+}$ efflux from perfused hearts. Furthermore, $Mg^{2+}$ efflux by phenylephrine was amplified by phorbol 12-myristate 13-acetate(PMA). This enhancement of $Mg^{2+}$ efflux by PMA was blocked by prazosin in perfused hearts. By contrast, the $Mg^{2+}$ influx could be induced by verapamil, nifedipine, ryanodine in perfused hearts, but not in myocytes. $W^7$, a $Ca^{2+}$/calmodulin antagonist, completely blocked the phenylephrine-induced $Mg^{2+}$ efflux in perfused hearts. In conclusion, $Mg^{2+}$ is responsible for the cardiac activity associated with ${\alpha}_1-adrenoceptor$ stimulation. The mobilization of $Mg^{2+}$ is decreased or increased by ${\alpha}_1-adrenoceptor$ stimulation in guinea pig hearts. These responses may be related specifically to the respective pathways of signal transduction. A decrease in $Mg^{2+}$ efflux by ${\alpha}_1-adrenoceptor$ stimulation in hearts can be through PKC dependent and intracellular $Ca^{2+}$ levels.

• 한국축산식품학회지
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• 제29권3호
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• pp.325-333
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• 2009

쇠고기의 저장 중 이취발생을 대변할 수 있는 품질인자를 탐색하고자 온도의존성의 관점에서 상호관계를 분석하였다. 특수관능기법인 R-index에 의한 이취검지시간을 탐지하였고, 이화학적, 생물학적 품질인자를 측정하였다. 먼저, 이취검지시간의 온도의존성의 관계식을 개발하여, 이에 따른 이취발생 indicator의 선발 요건을 유도하였다. 이화학적 분석은 VBN, pH, 육색, Warner-Bratzler shear force,그리고 생물학적 분석은 Pseudomonas spp., Lactic acid bacteria를 대상으로 하였다. 품질인자의 온도의존성은 Arrhenius 상수인 활성화에너지를 사용하여 분석하였다. 그 결과 VBN, pH, $a^*$값, LAB, Pseudomonas spp., WBSF, $L^*$값, $b^*$값의 순으로 이취발생과의 온도의존성이 유사하게 나타났으며, 상위권에 있는 pH와 $a^*$값에 비하여 환경적 요인에 안정한 VBN이 쇠고기 저장 중 이취발생의 최적 indicator인 것으로 탐색되었다.

• 기술혁신연구
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• 제29권1호
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• pp.1-38
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• 2021

본 논문에서는 에너지 섹터의 혁신성 제고를 위한 리빙랩(Living Labs) 활용 전략 수립에 관한 탐색적 분석 연구를 수행하였다. 기존 연구문헌을 통해 이론적 배경이 되는 리빙랩의 개념, 필수 구성요소, 혁신성 특성과 에너지 섹터의 혁신 이슈 유형을 확인할 수 있었다. 이를 토대로 리빙랩 필수 구성요소의 맞춤형 전략 수립과 혁신성 제고와의 연관성, 에너지 섹터에서의 혁신 이슈에 대한 접근으로 리빙랩 활용 가능성에 대해 에너지 리빙랩 사례 연구(해외 8건, 국내 1건)을 통해 분석되었다. 연구 결과, 리빙랩 필수 구성요소의 맞춤형 전략 수립이 혁신성 제고에 동인으로 작용 될 수 있으며, 리빙랩이 에너지 섹터의 혁신 이슈(수요관리, 공급기술, 기술사업화 촉진 및 수용성, 기술정책)에 대한 접근 방법론으로 효과적으로 활용 될 수 있음을 확인되었다. 사례연구 결과 기반으로 혁신성 기여 관점에서 리빙랩 사례별 동인을 도출하고 에너지 혁신이슈별 리빙랩 활용 전략을 수립하였다. 본 연구는 에너지 섹터에서의 혁신이슈에 대한 접근으로 리빙랩 모델의 활용 전략과 그 가치에 대한 탐색적, 기술적 분석 연구로서 종래에 시도되지 않았던 리빙랩 활용 전략 프레임워크를 제공할 수 있고, 에너지 리빙랩 활성화와 네트워크 형성에도 기여될 수 있다는 점에서 학술적·실용적·정책적 함의가 있다고 볼 수 있다.

• 대한치과교정학회지
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• 제43권6호
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• pp.294-301
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• 2013

Objective: To determine the interleukin (IL)-6 levels in gingival crevicular fluid (GCF) of patients with severe root resorption after orthodontic treatment and investigate the effects of different static compressive forces (CFs) on IL-6 production by human periodontal ligament (hPDL) cells and the influence of IL-6 on osteoclastic activation from human osteoclastic precursor (hOCP) cells in vitro. Methods: IL-6 levels in GCF samples collected from 20 patients (15 and 5 subjects without and with radiographic evidence of severe root resorption, respectively) who had undergone orthodontic treatment were measured by ELISA. The levels of IL-6 mRNA in hPDL cells and IL-6 protein in conditioned medium after the application of different uniform CFs (0, 1.0, 2.0, or 4.0 $g/cm^2$ for up to 72 h) were measured by real-time PCR and ELISA, respectively. Finally, the influence of IL-6 on mature osteoclasts was investigated by using hOCP cells on dentin slices in a pit-formation assay. Results: Clinically, the IL-6 levels were significantly higher in the resorption group than in the control group. In vitro, IL-6 mRNA expression significantly increased with increasing CF. IL-6 protein secretion also increased in a time- and magnitude-dependent manner. Resorbed areas on dentin slices were significantly greater in the recombinant human IL-6-treated group and group cultured in hPDL cell-conditioned medium with CF application (4.0 $g/cm^2$) than in the group cultured in hPDL cell-conditioned medium without CF application. Conclusions: IL-6 may play an important role in inducing or facilitating orthodontically induced inflammatory root resorption.

• KIEAE Journal
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• 제1권2호
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• pp.5-12
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• 2001

Through the harmony of natural and artificial systems a city is composed of, the ecology-oriented urban planning seeks for qualitative improvements of a city on which our life is based. To enhance the ecology-oriented urban planning, the followings are suggested by a comparative analysis of Korea with Germany regarding the development process, the instruments, and the establishment of indicators for the planning. Firstly, though our national land development plan is closely connected with B-plan, it has little to do with the natural environment. Moreover, the natural environment plan of the Ministry of Environment is almost impossible to carry out in terms of urban construction work. For this reason, the instrument for dealing with the development and environment plan systems together as well as the completion of the current plan system is needed for the ecologically acceptable urban development in the long term. Secondly, in order to realize what is mentioned above in the concrete it seems to be desirable for the system and the instrument to be devised at the extent of B-plan. The regulations of the plan should have strong legal binding force and practicality as well. The element of ecology-oriented urban planning are (1) degree of independence and appropriate density, (2) conservation of natural elements such as soil, water, animals and plants etc., (3) energy saving in land use, (4) activation of B-plan and inducement of active participation of residents. Thirdly, it will be useful to develop various kinds of indicators for the environment plan provided in advance so that the ecology-oriented urban developments may be under control. It also should be taken into consideration that the indicators are supposed to be comprehensive, representative, and practical enough to make the most of at the early stage of drawing up a plan. The kinds of indicators which can be used in the ecology-oriented urban development include (1) soil, (2) water, (3) vegetation and plants, (4) animals, (5) climate, and (6) transportation.

• 한국안광학회지
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• 제15권3호
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• pp.207-212
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• 2010

목적: 불화규소 아크릴레이트 RGP 콘택트렌즈(Boston EO, Boston XO)를 공기 중에서 플라즈마로 처리하여 표면의 성분, 형상, 습윤성의 변화를 연구하였다. 방법: 성분과 결합구조는 X-선광전자분광분석기(XPS), 형상과 거칠기는 원자현미경(AFM)으로 관찰하였으며, 습윤성의 변화는 접촉각을 측정하여 평가하였다. 결과: 플라즈마 처리에 의해 표면에서 불소는 크게 감소하고, 산소와 실리콘은 증가하였다. 산소를 포함하는 친수성기(C-O, Si-O)가 증가하고, 소수성인 표면이 감소하였으며, 접촉각이 증가하였다. 그러나 불소의 치환으로 생성된 C-O는 습윤성을 증진하지 않았다. 결과: 플라즈마 처리한 다음 6개월이 지나면 표면조성에는 큰 변화가 없으나, 접촉각이 다시 증가하였다. 결론: 불소의 함량이 높은 RGP 콘택트렌즈의 플라즈마 처리에 의한 습윤성 증가는 활성화된 표면과 Si-O의 증가, 소수성 표면의 감소에 의한 것으로 판단된다.

• 한국도서관정보학회지
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• 제8권
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• pp.155-184
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• 1981

The publication of the result of scholarly research is an integral part of the process by which learning is advanced. The university presses, as one of the major scholarly publishers are now confronted with many critical problems, such as the declining unit sales, the explosion of manuscripts, the challenge of new publishing technologies, etc., in performing the role of the scholarly communication system. The purpose of this study is to identify the problems imposed on the university presses and alternative strategies for them. For the study, the related literature to the subject were read, analyzed and synthesized, from which the overall prospect of the problems and alternative strategies are derived. The conclusion of the study can be summarized as follows: (1) The faith of the university should lie in its role to advance scholarly learning through production and dissemination of high-quality knowledge, and the university press should materialize such a faith. (2) The scholarly books, though not the best media of scholarly communication taking a side view of its timeliness and brevity, can perform the function of the best media for the specific subject and readers. (3) The scholarly books as national resource must be published for the scholars demanding them even though the publication can't help depending on the subsidiary fund. (4) For the survival and activation of the university presses, the following strategies should be examined, and put in force if necessary. (a) The role of the foundation su n.0, pporting the university presses should be expanded (b) The Co-operative system among the operations of the presses should be established. (c) It is desirable that the university without the press should participate in the university with the press for both the financial su n.0, pporting and the publicizing its faculty's manuscripts. (d) The positive efforts should be made for the increase of sales copies by implementing the dual-system of publication. (e) It is desirable that 'recording system' should be incorporated in the traditional publication system both for the lightening of financial problems and the explosion of publications. (f) It is necessary that the effective methods of the bibliographical control should be developed for the improvement of the scholarly communication. (g) Any kind of the permanent organization composed of the representatives from all the infrastructures of information industry should be established to study the character and direction of technological changes and to discern the better choice of specific, technologies in the scholarly communication system.