• Asian-Australasian Journal of Animal Sciences
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• 제25권6호
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• pp.772-784
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• 2012

Marker-assisted gene pyramiding aims to produce individuals with superior economic traits according to the optimal breeding scheme which involves selecting a series of favorite target alleles after cross of base populations and pyramiding them into a single genotype. Inspired by the science of evolutionary computation, we used the metaphor of hill-climbing to model the dynamic behavior of gene pyramiding. In consideration of the traditional cross program of animals along with the features of animal segregating populations, four types of cross programs and two types of selection strategies for gene pyramiding are performed from a practical perspective. Two population cross for pyramiding two genes (denoted II), three population cascading cross for pyramiding three genes(denoted III), four population symmetry (denoted IIII-S) and cascading cross for pyramiding four genes (denoted IIII-C), and various schemes (denoted cross program-A-E) are designed for each cross program given different levels of initial favorite allele frequencies, base population sizes and trait heritabilities. The process of gene pyramiding breeding for various schemes are simulated and compared based on the population hamming distance, average superior genotype frequencies and average phenotypic values. By simulation, the results show that the larger base population size and the higher the initial favorite allele frequency the higher the efficiency of gene pyramiding. Parents cross order is shown to be the most important factor in a cascading cross, but has no significant influence on the symmetric cross. The results also show that genotypic selection strategy is superior to phenotypic selection in accelerating gene pyramiding. Moreover, the method and corresponding software was used to compare different cross schemes and selection strategies.

• 정보처리학회논문지B
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• 제10B권6호
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• pp.599-610
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• 2003

웹은 정보 제공원으로서 중요한 역할을 하며 대부분의 웹 응용프로그램은 문서 중심이다. 문서는 문서설계자의 의도를 함축하고 있으며 이는 업무처리 과정의 자동화에 적극적으로 활용될 수 있다. 이러한 문서기능의 본질 파악을 통해 본 논문에서는 특별한 경우, 문서를 실행 가능한 컴퓨터 프로그램으로 보는 시각으로 접근하였다. 이를 위해 서식, 지식베이스, 규칙 그리고, 질의로 구성되는 능동문서 모델을 제안하였다. 이 모델의 각 요소는 문서의 재사용과 상호 운용성을 위해 XML로 일관되게 표현된다. 소개한 능동문서는 사용자 인터페이스를 제공하는 수동적인 역할뿐만 아니라 문서설계자가 의도하는 문서처리 절차와 업무규칙을 기계가 읽고 추론하여 처리할 수 있게 하는 문서이다. 이를 통해 문서와 기계가 상호작용을 할 수 있으며 다른 응용 프로그램과 협력할 수도 있다. 이러한 능동문서의 적용 가능함을 보이기 위해 기업 간 거래(B2B) 시스템에서 구매주문 처리의 예를 보였다. 서식문서를 컴퓨터 프로그램의 시각으로 바라보는 본 논문의 접근법을 통해 본 연구는 문서중심의 지능적인 응용프로그램 개발을 가속화하는 발판을 마련할 수 있을 것이다. 요컨대 본 논문에서 제시한 능동문서는 지식표현 및 처리기능이 내장되어 있는 바, 시맨틱 웹(Semantic Web)이 추구하는 문서의 역할을 담당할 수 있을 것으로 기대한다.

• 지구물리와물리탐사
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• 제13권1호
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• pp.109-117
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• 2010

소니 플레이스테이션3 (PS3) 비디오 게임 콘솔을 이용하여 대용량자료에 고성능 계산을 적용시키기 위하여 개인용컴퓨터 (PC) 의 윈도우 시스템과 PS3로 구성된 하이브리드 시스템을 제작하였다. 이 시스템의 성능을 검증하기 위해 파형모양의 유사도를 이용하여 미세지진의 멀티플렛을 알아내는 실시간 멀티플렛 식별자 (RTMI)를 수행하여보았다. RTMI의 핵심 알고리즘인 상호상관 계산은 PS3 플랫폼에 최적화 되었고 자료의 압출력을 포함하는 다른 계산들은 PC 상에서 수행되었다. 이 경우에 알고리즘의 핵심 부분이 원래의 경우보다 50 배 이상 빨리 수행되어 결과적으로 개발된 시스템은 과거 400개의 신호밖에 처리하지 못하던 것을 총 2100개까지의 미소진통 신호등을 처리 할 수 있게 하였다. 이 결과는 자료전송시간이 계산시간에 비해 무시할 수 있는 한 PS3를 이용한 대용량 자료의 고성능 계산이 가능하다는 것을 잘 보여주고 있다.

• 한국식품영양학회지
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• 제30권2호
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• pp.181-190
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• 2017

Functional foods are of great significance since our society is accelerating into aging. An aging society has many physiological metabolic diseases such as hypertension, diabetes, heart disease, cancer, dementia and geriatric diseases. Fundamental treatments for the elderly are almost impossible and the social burden is heavy. If these diseases can be prevented or alleviated by improving dietary habits using functional foods, the significance would be very large. Pomegranate has been found to have 124 different kinds of phytochemicals. Polyphenols have a wide range of protective effects including various physiological metabolic diseases and cancers. It is necessary to develop functional foods such as preservatives and food extenders which can contribute to food safety, required in the food industry, by using such bioactive substances. Pomegranates have been reported to decrease the impact of many serious illnesses. There is a considerable amount of bioactive substances in the peel of a pomegranate, which has potent anticancer, antioxidant, antimicrobial and anti-apoptotic properties. Unfortunately, the peel is typically discarded after processing. Despite knowledge regarding the bioactive substances in the pomegranate peel and peel extracts, including their functionality and diversity, the knowledge is not well known by consumers in general. The aim of this study was to review up to date research trends for processing and developing new functional foods by utilizing nutritional functional substances, favourite food materials, and materials for processing food contained in pomegranate peels and pomegranate peel extracts. This study will summarize the data found in pomegranate peel and pomegranate peel extract literature mainly recently published in Science Direct. There are polyphenolic compounds (ellagitannins, punicalagin, proanthocyanidin, flavonoids, polysaccharides, etc.) in the fruit peel, making up about 50% of the pomegranate's weight. The polyphenol content of a pomegranate fruit peel is 149.91 mg/g, which is about 100 times higher than the juice. Paying attention to the fact that the ellagitannin content (14.22 mg/g) in the fruit peel is also twice as high as that of the fruit juice and seeds, that confirms the possibility of utilizing the peel as a food ingredient capable of developing new, functional bioactive foods.

• 한국도로학회논문집
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• 제17권6호
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• pp.37-45
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• 2015

PURPOSES : The purpose of this study is to validate the design criteria of the concrete modular road system, which is a new semi-bridge-type concept road, through a comparison of numerical analysis results and actual loading test results under static axial loads. METHODS : To design the semi-bridge-type modular road, both the bridge design code and the concrete structural design code were adopted. The standard truck load (KL-510) was applied as the major traffic vehicle for the design loading condition. The dimension of the modular slab was designed in consideration of self-weight, axial load, environmental load, and combined loads, with ultimate limit state coefficients. The ANSYS APDL (2010) program was used for case studies of center and edge loading, and the analysis results were compared with the actual mock-up test results. RESULTS : A full-scale mock-up test was successfully conducted. The maximum longitudinal steel strains were measured as about 35 and 83.5 micro-strain (within elastic range) at center and edge loading locations, respectively, under a 100 kN dual-wheel loading condition by accelerating pavement tester. CONCLUSIONS : Based on the results of the comparison between the numerical analysis and the full-scale test, the maximum converted stress range at the edge location is 32~51% of the required standard flexural strength under the two times over-weight loading condition. In the case of edge loading, the maximum converted stresses from the Westergaard equation, the ANSYS APDL analysis, and the mock-up test are 1.95, 1.7, and 2.3 times of that of the center loading case, respectively. The primary reason for this difference is related to the assumption of the boundary conditions of the vertical connection between the slab module and the crossbeam module. Even though more research is required to fully define the boundary conditions, the proposed design criteria for the concrete modular road finally seems to be reasonable.

• 한국지역사회생활과학회지
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• 제22권1호
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• pp.5-20
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• 2011

It is very important that the development of rural tourism resources and contents for agritourism increases rural household income and vitalizes local economy. In this sense, accelerating the rural traditional food materials into resources plays significant roles for the local economy. The farm-restaurant project, as a part of a development of rural traditional foods can not only help popularize the rural food-culture, but it also promote the consumption of local products by urban customers. It is difficult to manage both types of restaurants which are the dining type and the experience-centered farm restaurants as a farmer. In particular, the managers of the farm restaurants have some operational problems in developing a new menu and an experiential-program using their local farm products. The purpose of this study was to present steps that can be used for the existing menu-improvement and developing new menu processes of the farm restaurants that have been in operation for more than two years. By the purpose of menu developing for a restaurant, this research is designed for the case study. For collecting date for the study, we gained knowledge about the issues concerning menus from in depth interviews with the managers in two subject farm restaurants. The results suggested that a new menu, such as table d'h$\^{o}$te, $\`{a}$ la carte meals, specialties, kids meal, various dressing, are based on solving issues such as a limitation of food materials and the necessity of a kids meal in dining type of farm restaurants. Also, the suggested new menu, such as seasonal specialties and side dishes, are based on solving issues such as urgent development of various experiential programs and necessity of seasonal specialties in experiential type of farm restaurants.

• 중소기업융합학회논문지
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• 제2권2호
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• pp.27-34
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• 2012

글로벌 경쟁구도 시대에 기술의 창출 확산 활용을 통한 혁신주도형 경제로의 변화가 전 세계적으로 가속화되고 있다. 글로벌 기술 및 시장 환경의 변화에 따라 국내 중소기업들의 해외 진출에 대한 기업 지원에 있어서 체계적인 지원 체계 및 효율적인 정보 관리에 대한 진화가 요구된다. 이를 위해 해외 주요 국가들의 기술 수준 및 사업화 동향을 조사, 분석하고, 주요 국내외 기술사업화 기관 및 프로그램들의 지원 유형 및 비즈니스 모델을 전략적으로 분류, 분석하며, 이를 토대로, 국내 중소기업들의 해외 글로벌 시장 진출을 위한 진출전략 및 정보 지원방안을 도출하고자 한다.

• Archives of Reconstructive Microsurgery
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• 제4권1호
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• pp.9-15
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• 1995

Free vascularized composite tissue transfer is more frequently underwent for reconstruction of complicated tissue defects with the recent advance of microsurgery. But postoperative result was not satifactory because of donor site morbidity, flap bulkiness and cosmetic problem. So would no longer be a problem if we can obtain the exact donor tissue required for the recipient site as allotransplantation and designing the flap. Allotransplantation has been resolved with the recent development of immunosuppressive agents, while reconstruction has made great progress with the refinement of microsurgical techniques in the last 20 years. The final sucess or failure of the operative procedure in transplantation is so utterly dependent no the availability of strategies that can control the immune system effectively, selectively, safely to allow allotransplantation of a nonvital body part. 1 used 2 strains of rats, BUF and LEW, for the limb allotransplantation as a composite tissue transfer. The primary goal of this program is to improve results in clinical transplantation by accelerating the transformation of new immunological knowledge into useful medicine. Two of the most promising new immunosuppressive compounds are FK-t06(FK) and rapamycin(RPM). Both drugs are antibiotic macrolide fungal fermentation products that presumably suppress the immune system in ways similar to cyclosporin(CyA). This study shows that two new immunosuppressive drugs compare the immunosuppressive activity and effectiveness of FK-506 and RPM for prevention of the limb allograft rejection in the rat. Additional experiments investigate the dose, route of administration and histologic findings. These data demonstrates that rapamycin is far more potent and effective than FK-506 when both compounds are administered by the intraperitoneal route, as well as prolonged graft survival significantly in a dose-route dependent manner. These results lead to the view that vascularized allograft composite tissue transfer can become a reality with the expectation of possible future application in reconstructive surgery of humans.

• 대한전자공학회논문지SD
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• 제45권10호
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• pp.53-58
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• 2008

본 논문은 네트워크 프로세서의 패킷 처리 능력 향상을 위한 새로운 명령어 세트를 제한한다. 제안하는 명령어는 패킷 헤더의 결합 연산을 가속화 할 수 있으므로 보다 효율적인 패킷 처리를 수행할 수 있다. 또한 overlay 명령어 처리를 위한 전용 하드웨어 구조를 설계하여 추가 하드웨어로 인한 비용을 최소화 하였다. 이를 위해 LISA 언어를 이용하여 네트워크 프로세서 기본 아키텍처를 설계하고 overlay 블록을 배럴 시프터를 기반으로 최적화 하였다. 이를 합성하여 면적 및 동작 지연시간을 비교하였으며, 컴파일러의 CKF(Compiler Known Function)를 이용하여 C레벨의 매크로 함수에 할당하고 어플리케이션 프로그램에 대한 실행 사이클 및 실행 시간을 비교하여 성능 향상을 확인하였다. Coware사의 processor designer, compiler designer를 이용하여 실험하였으며 Synopsys의 TSMC $0.25{\mu}m$로 합성한 결과 20.7%의 동작 지연시간 감소를 보였고, 전체 실행 사이클에선 제안하는 명령어 세트에 의해 30.8%의 성능 향상을 보였다.

• 한국도서관정보학회지
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• 제51권1호
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• pp.43-70
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• 2020

특화도서관의 설립이 가속화되고 있는 상황에서, 본 연구는 김포시 시립도서관 운영이 20년이 됨에 따라 김포시 지역별로 산재해 있는 특화도서관 전체의 체계를 재정립함으로써, 타 지역과 차별화할 수 있는 김포시 도서관만의 특화된 비전과 전략 설정을 목적으로 하고 있다. 본 연구에서는 김포시 도서관의 운영상의 문제를 크게 3가지 관점에서 논의하였다. 먼저, 특화주제 선정의 문제점이다. 다음으로 특화자료이용의 문제이다. 마지막으로 실질적인 특화프로그램 미운영의 문제이다. 이러한 분석을 바탕으로 특화주제 발전 방향은 크게 3가지로 제안하였다. 첫째, 지역 콘텐츠 및 이용자 요구에 기반한 특화주제 선정이다. 둘째, 특화서비스 활성화 방안의 마련이다. 셋째로, 지역 내 특화네트워크를 강화하는 것이다.