• Journal of Veterinary Clinics
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• v.20 no.1
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• pp.142-144
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• 2003

A 3-year-old, 38 kg, male Golden Retriever dog was referred to Veterinary Teaching Hospital of Konkuk University because of chronic formation of crust on nasal bridge and planum nasale. Abnormalities of physical examination included hyperkeratosis on the footpad, symmetrical alopecia and erythma around olecranon, and crust on nasal bridge and planum nasale. Results of the hematological examination showed a mild leukopenia with neutropenia, monocytosis, and mild lymphocytosis. In addition, the result of serum chemistry and thyroid gland profile were normal. Results of fungal and bacterial culture was negative. Acanthocytes in cytological evaluation of nasal crust were observed in direct microscopic examination. Examination of skin biopsy exhibited vacuolation of basal cell layer, degeneration and necrosis of basal cell with defluxion, mild monocytes filtrations between epidermis and dermis, and mild acanthosis with hyperkeratinization. Based on results of examination described above, Discoid Lupus Erythematosus (DLE) was diagnosed.

• Applied Microscopy
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• v.29 no.3
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• pp.331-341
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• 1999

Examination of the morphology of red blood cells in the urine has been shown to be a promising adjunct in determining whether hematuria represents glomerular or nonglomerular bleeding. This is due to distortion of RBCs as they Pass across the basement membrane of the glomerular capillaries. It is concluded that is method can greatly help the clinician in distinguishing between glomerular and nonglomerular bleeding in patients with hematuria and channeling such patients toward the most appropriate investigations. We have experimented dysmorphic red blood cells that 5 patients of the hematuria are distorted with irregular outlines and often have small blobs extruding from the red cell membrane. Tried urinary sediments were seen with phase contrast microscope and confirmed scanning electron microscope. There are seen acanthocytes, anulocytes, ghost cells and sphero-echinocytes in dysmorphic erythrocytes. Clinical diagnosis was referred from the result of the biopsy-proven. Scanning electron microscopic findings of the hematuria are good diagnostic tool that disclose in distorted red blood cells from patients with glomerular disorders.