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A case of Discoid Lupus Erythematosus (DLE) in a Golden Retriever dog  

Won, Dong-Sun (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Hong, Eun-Sil (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Jung, Man-Bok (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Kim, Hyun-Jin (Department of Veterinary Pathology, College of Veterinary Medicine, Chonnam University)
Park, Nam-Yong (Department of Veterinary Pathology, College of Veterinary Medicine, Chonnam University)
Park, Chul (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Jung, Byung-Hyun (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Park, Hee-Myung (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Publication Information
Journal of Veterinary Clinics / v.20, no.1, 2003 , pp. 142-144 More about this Journal
Abstract
A 3-year-old, 38 kg, male Golden Retriever dog was referred to Veterinary Teaching Hospital of Konkuk University because of chronic formation of crust on nasal bridge and planum nasale. Abnormalities of physical examination included hyperkeratosis on the footpad, symmetrical alopecia and erythma around olecranon, and crust on nasal bridge and planum nasale. Results of the hematological examination showed a mild leukopenia with neutropenia, monocytosis, and mild lymphocytosis. In addition, the result of serum chemistry and thyroid gland profile were normal. Results of fungal and bacterial culture was negative. Acanthocytes in cytological evaluation of nasal crust were observed in direct microscopic examination. Examination of skin biopsy exhibited vacuolation of basal cell layer, degeneration and necrosis of basal cell with defluxion, mild monocytes filtrations between epidermis and dermis, and mild acanthosis with hyperkeratinization. Based on results of examination described above, Discoid Lupus Erythematosus (DLE) was diagnosed.
Keywords
Discoid lupus erythematosus(DLE); acanthocytes; Dog;
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