• 한국추진공학회:학술대회논문집
• /
• 한국추진공학회 2011년도 제37회 추계학술대회논문집
• /
• pp.97-103
• /
• 2011

본 논문에서는 엔진 비상보호시스템 구성 시 주요 고려 사항과 엔진 선행 개발 시험에서의 적용사례를 제시하였다. 액체로켓엔진 선행 개발 시험을 위해 적용된 비상보호시스템은 시험 중 발생한 모든 오작동 상황에서 오류 없이 작동하여 시험을 중지함으로써 추가적인 오작동의 전파를 방지하여 시험시제와 시험설비를 안전하게 보호하는 역할을 성공적으로 수행하였다. 본 연구 결과는 향후 엔진시험을 위한 비상보호시스템 개발 시 유용하게 활용될 것이다.

• 대한소아치과학회지
• /
• 제21권2호
• /
• pp.555-560
• /
• 1994

Among the permanent teeth. the first permanent molars play the greatest role in occlusion and function. So, the congenital missing, abnormal reuption or abnormal formation of the first permanent molars in the course of arch development would inflict normal development of dental arches. Therefore, early detection of abnormal cases related to first permanent molars and understanding of current and predictable clinical problems are essential for proper occlusal guidance in children. With the aim of investigating the clinical patterns of delayed eruption of first permanent molars in children, panoramic tomograms of the childern in mixed and early permanent dentition were observed and analyzed. The results were as follows: 1. Among the delayed eruption of first permanent molars, on tooth or bilateral teeths were affected most frequently. Delayed eruption was more prevalent in maxilla than in mandible. 2. The formation of tardily erupted teeth were also delayed. 3. Delayed eruption was generally limited in first molars or molar segments. 4. Delayed eruption of first permanent molars is accompanied by abnormal position of tooth germs, for example, ectopic eruption, delayed dental age, delayed localized tooth formation and generalized congenital missing. 5. There was a tendency of delayed formation or congenital missing of second molars distal to tardily erupted 1st molars. And that was more marked in maxilla than in mandible. 6. There was reported that affected 1st molars show various size and shapes. Maxillary 1st molars showing delayed eruption showed a tendency of having 3 cusps. But, tardily erupted mandibular 1st molars showed no significant reduction in mesiodistal dimension, as reported. 7. In some cases, the delayed eruption of 1st permanent molars was associated with ectopic eruption, but their formation was not usually retarded. 8. In skeletal class III cases, there showed a tendency of mandibular 1st molars to erupt earlier than maxillary 1st molars with greater interval than in normal occlusion.

• 대한원격탐사학회지
• /
• 제25권1호
• /
• pp.1-10
• /
• 2009

각종 위성자료와 현장 관측자료를 이용하여 2004년 겨울철 황해 연안해역 이상수온 상승 현상과 외해의 해양 변동과의 연관성에 대하여 연구하였다. 위성자료에 의하면, 2003년 황해의 평균 해수면온도는 $10^{\circ}C$ 정도였고, 2004년의 평균 해수면온도는 $13^{\circ}C$ 정도로 약 $3^{\circ}C$ 정도 높았다. 현장관측 자료에서는 2003년 황해의 평균 표층수온은 $9.85^{\circ}C$ 정도였고, 2004년의 평균 표층수온은 $12.17^{\circ}C$ 정도로 위성자료와 마찬가지로 약 $3^{\circ}C$ 정도 높았다. T-S diagram 분석에 의하면, 2003년은 황해 수괴와 동중국해 수괴를 아주 명확하게 구분되었지만, 2004년에는 양 수괴의 구분이 명확하지 않았다. 2003년의 평균 기온과 풍속은 각각 $5.23^{\circ}C$, 4.81 m/s 이고, 9004년의 평균 기온과 풍속은 각각 $5.61^{\circ}C$, 4.52 m/s 로 유사하였다. 그러나 2003년에는 북서풍이 우세하였으나, 2004년에는 다양한 북풍 계열의 바람이 불어서 풍향이 달랐다. 2004년 겨울철 황해 연안해역의 이상수온 상승은 대기의 영향보다 외해 해양 변동과 깊은 연관성이 있는 것으로 판단되었고, 이에 대해서는 추후 연구가 이루어질 것이다.

• 한국환경보건학회지
• /
• 제35권6호
• /
• pp.486-490
• /
• 2009

In January 2009, the water quality of offshore around the Incheon coast was evaluated by bioassay using early development systems of a sea urchin species, Hemicentrotus pulcherrimus. The results of performing biological evaluations on seawater samples from total of thirteen sites, showed that the formation rates of normal pluteus larva varied from 18% to 71%. In site 5 the seawater sample led to an averaage formation rate of normal larva of 18%, the highest abnormal formation rate hindering the early embryo development of the experimental animal, while that of site 3 averaged 71%, the highest formation rate of normal larva. Seawater samples from site 1, 2, 4, 7, 9, 10, 11 and 12, resulted in average formation rates of normal larva from 33% to 56%, which indicates the developmental damage of early embryos is not severe. Seawater samples from site 5, 6, 8 and 13, resulted in average formation rates of normal larva from 18% to 21% which there was strong damage to the development of early embryos.

• 환경생물
• /
• 제22권3호
• /
• pp.376-380
• /
• 2004

In August 2003, the water quality of offshore waters along the Incheon coast of Korea was evaluated by biological evaluation using gametes, embryos and early development systems of a starfish species (Asterina pectinifera). As the result of performing biological evaluations on seawater samples from a total thirteen sites, the formation rate of normal larva was 16-68%. At seawater sample from site 5 and 13, formation rate of normal larva averaged 16%, the most abnormal rate hindering the early embryo development of the experimental animal, while that of site 3 averaged 68%, the highest formation rate of normal larva. At seawater sample from site 2, 4, 7, 9, 10, 11, 12, formation rate of normal larva averaged 33-54%, those which damage the development of early embryos slightly. At seawater sample from site 1, 5, 6, 8, 13, formation rate of normal larva averaged 16-28%, those which damage the development of early embryos strongly.

• 한국의류학회지
• /
• 제29권7호
• /
• pp.1018-1026
• /
• 2005

Recent development of 3D scanner and software is regarded as a promising method of acquiring replicas from human body indirectly. It would be very helpful if we could predict the characteristics of 2D pattern from the simple parameters related to 3D shape for ordinary user. Therefore, in this study, investigation of 2D pattern of waist/abdominal area from the 3D geometrical model was conducted for the pattern development of waist nipper. To create body models and develop the surface of them, one ortho commonly used CAD/CAM program, IDEAS(UGS-plm solutions, USA) was used. As for the size of the models, the width, thickness, and circumference ranges of adult women's torso reported in National Anthropometric Survey of Korea (1997) were used as a standard model. Seven size variations were made by changing the width of the waist only, from 19 cm to 40 cm. Therefore, simulated body models include not only the normal body but also obese body who has wider waist and abdomen width than hip width. As results, it was found that the curvature of the unfolded 2D pattern around the abdominal area decreases as the waist width increases. As the width of the waist increases more and more, so that the comparative ratios around the torso becomes in abnormal ranges, there appears inflection points and the direction of curvature was changed. 2D Patterns obtained in this research were quantified by curvature, length of the curve and angle of deflection in the reference frame box for the convenience of the actual pattern making process. It was also possible to find that the shape of patterns of abnormal body resulted in a quite interesting change in the curves of 2D pattern, which could be applied to the custom made waist nipper for obese women.

• 한국발생생물학회지:발생과생식
• /
• 제24권4호
• /
• pp.297-306
• /
• 2020

Repetitive changes in the intracellular calcium concentration ([Ca²⁺]i) triggers egg activation, including cortical granule exocytosis, resumption of second meiosis, block to polyspermy, and initiating embryonic development. [Ca²⁺]i oscillations that continue for several hours, are required for the early events of egg activation and possibly connected to further development to the blastocyst stage. The sources of Ca²⁺ ion elevation during [Ca²⁺]i oscillations are Ca²⁺ release from endoplasmic reticulum through inositol 1,4,5 tri-phosphate receptor and Ca²⁺ ion influx through Ca²⁺ channel on the plasma membrane. Ca²⁺ channels have been characterized into voltage-dependent Ca²⁺ channels (VDCCs), ligand-gated Ca²⁺ channel, and leak-channel. VDCCs expressed on muscle cell or neuron is specified into L, T, N, P, Q, and R type VDCs by their activation threshold or their sensitivity to peptide toxins isolated from cone snails and spiders. The present study was aimed to investigate the localization pattern of N and P/Q type voltage-dependent calcium channels in mouse eggs and the role in fertilization. [Ca²⁺]i oscillation was observed in a Ca²⁺ contained medium with sperm factor or adenophostin A injection but disappeared in Ca²⁺ free medium. Ca²⁺ influx was decreased by Lat A. N-VDCC specific inhibitor, ω-Conotoxin CVIIA induced abnormal [Ca²⁺]i oscillation profiles in SrCl₂ treatment. N or P/Q type VDC were distributed on the plasma membrane in cortical cluster form, not in the cytoplasm. Ca²⁺ influx is essential for [Ca²⁺]i oscillation during mammalian fertilization. This Ca²⁺ influx might be controlled through the N or P/Q type VDCCs. Abnormal VDCCs expression of eggs could be tested in fertilization failure or low fertilization eggs in subfertility women.

• Clinical and Experimental Reproductive Medicine
• /
• 제50권3호
• /
• pp.192-199
• /
• 2023

Objective: This study was conducted to investigate chromosomal abnormalities and their correlations with clinical and radiological findings in females with primary amenorrhea (PA). Methods: Detailed forms were recorded for 470 females, including the construction of three-generation pedigrees. Peripheral venous blood was drawn, with informed consent, for cytogenetic analysis. Results: An abnormal karyotype was found in 16.38% of participants. The incidence of structural abnormalities (6.8%) exceeded that of numerical abnormalities (6.15%). Turner syndrome represented 45% of all numerical abnormalities. Furthermore, the Y chromosome was detected in 5% of females with PA. Among the structural chromosomal abnormalities detected (n=32) were mosaicism (25%), deletions (12.5%), isochromosomes (18.75%), fragile sites (3.12%), derivatives (3.12%), marker chromosomes (3.12%), and normal variants (29.125%). An examination of secondary sexual characteristics revealed that 29.6% of females had a complete absence of breast development, 29.78% lacked pubic hair, and 36.88% exhibited no axillary hair development. Radiological findings revealed that 51.22% of females had a hypoplastic uterus and 26.66% had a completely absent uterus. Abnormal ovarian development, such as the complete absence of both ovaries, absence of one ovary, one absent and other streak, or both streak ovaries, was observed in 69.47% of females with PA. Additionally 43.1%, 36.1%, 67.4%, and 8% of females had elevated levels of serum follicle-stimulating hormone, luteinizing hormone, thyroid-stimulating hormone, and prolactin, respectively. Conclusion: This study underscores the importance of karyotyping as a fundamental diagnostic tool for assessing PA. The cytogenetic correlation with these profiles will aid in genetic counseling and further management of the condition.

• 한국수정란이식학회지
• /
• 제31권2호
• /
• pp.109-116
• /
• 2016

The recovery of epididymal sperm in animals is considered as one of the important tools to preserve high value or endangered species. However, there are no appropriate castrating indicators such as months of age in bull, sperm morphology, and motility, particularly in young Korean native bull (Hanwoo). Therefore, this study aimed to investigate sperm number, morphology, and motility of sperm in the epididymis tail of young Hanwoo bulls at 8 and 15 months of age. After castration, epididymal tails were collected and minced with blades to recover sperm. In experiments 1 and 2, sperm number, morphology, and motility were examined. Total number of sperm and percentage of normal sperm from bulls at 8 months of age was lower than that of bulls at 15 months of age after collection (P<0.05). Percentage of abnormal head, tail, proximal cytoplasmic droplet, dead and damaged acrosome of sperm from bulls at 8 months of age were higher than those of bulls at 15 months of age (P<0.05). In experiment 3, sperm motility from bulls at 8 and 15 months of age were examined before freezing and after thawing. Frozen-thawed sperm at 8 months of age showed low total motility and motile sperm with ${\geq}25{\mu}m/sec$ compared to those at 15 months of age and commercially-used sperm (P<0.05). In conclusion, sperm derived from the epididymal tail of bulls at 8 months of age showed high abnormal morphology and poor motility, which are not adequate for AI and IVF. On the other hand, sperm derived from the epididymal tail of bulls at 15 months of age showed high normal morphology and motility.

• 한국균학회지
• /
• 제18권4호
• /
• pp.225-232
• /
• 1990

몇몇 배양조건이 유성 또는 무성분화에 미치는 영향을 조사하여, 유성분화 결손 돌연변이주를 분리하기 위한 효율적인 조건을 찾고자 하였다. 무성분화는 억제하며, 유성분화는 촉진시키는 여러조건중 Casein hydrolysate를 첨가한 최소배지에 밀봉 배양하는 것이 가장 효율적인 조건으로 선택되었다. 접종 후 20시간 이전에 밀봉하고 계속 배양하면, 유 무성분화 모두가 억제되나, 밀봉 후 20시간 정도 후에 밀봉을 해제하면 유성분화만이 진행되었다. 이러한 성질을 이용하여 유성분화과정에 이상이 일어난 돌연변이주를 대랑 분리해 냈었으며, 이들의 분화양상에 따라 크게 3 group : NSD(never in sexual development), BSD(block in sexual development), ASD(abnormal in sexual development)으로 분류하였다. NSD 돌연변이주는 $H{\ddot{u}}lle$ cell이나 cleistothecia 등의 유성생식기관을 전혀 생성하지 못하였고, BSD 돌연변이주는 $H{\ddot{u}}lle$ cell, cleistothecia, crozier, asci 또는 ascospore 형성 중 어느 과정에서 중단되어 분화가 끝가지 진행되지 못하였으며, ASD 돌연변이주는 유성분화의 최종단계가지 진행은 되지만 유성생식 기관의 생성시기나 양이 야생형과 현저하게 차이를 보였다.