• Title/Summary/Keyword: abnormal changes

Search Result 872, Processing Time 0.024 seconds

Evaluation of osseous changes of TMJ in internal derangement and osteoarthritis patients using MRI (자기공명영상을 이용한 악관절내장증환자와 악관절증환자의 골변화에 관한 연구)

  • Cho Su-Beom;Koh Kwang-Joon
    • Imaging Science in Dentistry
    • /
    • v.31 no.3
    • /
    • pp.159-164
    • /
    • 2001
  • Purpose: To evaluate the osseous changes of TMJ in internal derangement and osteoarthritis patients using MRI. Materials and Methods: MR images of 111 TMJs in 64 patients were analyzed to evaluate the osseous changes, 111 TMJs were divided into 6 groups according to the radiologic Stages by Schellhas and Wilkes. On MR images, we evaluate the osseous changes of articular eminence and condylar head. Results: The most frequent Stage in internal derangement of TMJ was Stage I. And 28 joints (25.2%) revealed osteoarthritis with internal derangement. When osseous change of articular eminence and condylar head occur, flattening was the most common osseous change. Sclerosis was observed in all Stages and osteophytosis of condylar head was observed in Stage II (1.8%) and III (0.9%). Out of 28 joints with osteoarthritis, 6 joints (21.4%) showed joint effusion. Conclusion: MR image revealed abnormal configuration of disk, but the detection of minimal osseous change was subtle.

  • PDF

PSYCHOLOGIC CHANGES AFTER ORTHOGNATHIC SURGERY OF DENTOFACIAL DEFORMITY PATIENTS (턱기형의 악교정수술후 환자의 심리적변화)

  • Kim, Seon-Jong;Kim, Myeong-Rae;Kim, Yong-Han;Park, Young-Sook
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • v.17 no.4
    • /
    • pp.311-316
    • /
    • 1995
  • This is to study the presurgical motivation, psychological changes and self satisfaction after the surgical treatment of dentofacial deformities. The subjects were 34 patients that the orthognathic surgeies were rendered and followed-up over 6 months. The results were as followings ; 1. The analysis of MMPI profiles in clinical scale reveals that 8.8%(3 patients) of neurologic type, 2.9% (1 patient) of personality problem type and none of psychotic type, while 88.3% of showed no abnormal findings in psychologic status. 2. The significant differences of personality characteristics were noticed in the Depression(D), Hypochondriasis(Hs), Musculinity-Feminity(Mf) were changed significantly following the orthognathic surgeries.(P<0.05) 3. The self assesment of the esthetic results were satisfactory in 78.6%, while no changes in 14.3%.

  • PDF

Examination of $\alpha$-terpinene on Primary Eye Irritancy and Skin Sensitization

  • Park, Byeoung-Soo;Choi, Won-Sik;Lee, Sung-Eun
    • Molecular & Cellular Toxicology
    • /
    • v.3 no.1
    • /
    • pp.68-75
    • /
    • 2007
  • [ $\alpha$ ]-Terpinene has been known as a repellent against the mosquito Culex pipiens pallens Coquillett based on a human forearm bioassay. $\alpha$-Terpinene showed significantly greater repellency than a commercial formulation, N, N-diethyl-m-methylbenzamide (deet). In this study, skin and eye sensitivity of $\alpha$-terpinene (2%) was examined with bioassays using white New Zealand rabbits. There were somewhat gross and histological changes observed in these treatments. Eye irritancy assays examined gross changes to cornea, iris and conjuctiva, and histological changes to smear of ocular discharge and eye tissue. Treated rabbits were divided into two cohorts, a saline washed cohort (W) or a non-washed cohort (NW). Opacity of cornea and redness, chemosis and discharge of conjuctiva were observed in both cohorts, but disappeared within 4 and 10 days in W and NW, respectively. Main components of ocular discharges were fibrin, epithelial or epitheloid cells, lymphoid cells, erythrocytes and granulocytes. These abnormal cellular components disappeared within 4 days and 10 days in W and NW, respectively. No permanent histological differences were observed between the two cohorts. However, severe irritation was determined as 57.2 of I.I.O.I value on the first day after treatment. These findings indicate a spray-type solution containing 2% $\alpha$-terpinene may serve as an alternative mosquito repellent and further studies need to reduce the eye irritation with formulation changes.

Orthognathic surgery and temporomandibular joint symptoms

  • Jung, Hwi-Dong;Kim, Sang Yoon;Park, Hyung-Sik;Jung, Young-Soo
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • v.37
    • /
    • pp.14.1-14.11
    • /
    • 2015
  • The aim of this article is to review temporomandibular joint symptoms as well as the effects of orthognathic surgery(OGS) on temporomandibular joint(TMJ). The causes of temporomandibular joint disease(TMD) are multifactorial, and the symptoms of TMD manifest as a limited range of motion of mandible, pain in masticatory muscles and TMJ, Joint noise (clicking, popping, or crepitus), myofascial pain, and other functional limitations. Treatment must be started based on the proper diagnosis, and almost symptoms could be subsided by reversible options. Minimally invasive options and open arthroplasty are also available following reversible treatment when indicated. TMD manifesting in a variety of symptoms, also can apply abnormal stress to mandibular condyles and affect its growth pattern of mandible. Thus, adaptive developmental changes on mandibular condyles and post-developmental degenerative changes of mandibular condyles can create alteration on facial skeleton and occlusion. The changes of facial skeleton in DFD patients following OGS have an impact on TMJ, masticatory musculature, and surrounding soft tissues, and the changes of TMJ symptoms. Maxillofacial surgeons must remind that any surgical procedures involving mandibular osteotomy can directly affect TMJ symptoms, thus pre-existing TMJ symptoms and diagnoses should be considered prior to treatment planning and OGS.

Study of Histochemical Changes of Mouse Ovary Under X-ray Irradiation (방사선 조사선량에 따른 생쥐 난소의 조직화학적 변화)

  • Yoon, Chul-Ho
    • Journal of radiological science and technology
    • /
    • v.29 no.4
    • /
    • pp.275-284
    • /
    • 2006
  • This research investigated the morphological changes of folliculus ovary according to the dose of the X-rays when mice were exposed to X-rays, in terms of histochemical reaction. Dyeing methods such as Masson's trichrome method and reticular fiber method were used. The morphological changes of growing folliculus ovary got distinct as the dose of X-rays increased. Especially, the nuclei of granular cells showed manifest condensation and the changes of the transparent zone were distinct. As a result of histochemical reaction according to Masson's trichrome method and reticular fiber method, the changed granular cells, the deformed basilar membrane of folliculus ovary and the abnormal arrangement of the reticular fiber were observed.

  • PDF

A Study on the PET/CT Fusion Imaging (PET/CT 결합영상진단 검사에 관한 연구)

  • Kim, Jong Gyu
    • Korean Journal of Clinical Laboratory Science
    • /
    • v.36 no.2
    • /
    • pp.193-198
    • /
    • 2004
  • PET/CT combines the functional information from a positron emission tomography (PET) exam with the anatomical information from a computed tomography (CT) exam into one single exam. A CT scan uses a combination of x-rays and computers to give the radiologist a non-invasive way to see inside your body. One advantage of CT is its ability to rapidly acquire two-dimensional pictures of your anatomy. Using a computer these 2-D images can be presented in 3-D for in-depth clinical evaluation. A PET scan detects changes in the cellular function - how your cells are utilizing nutrients like sugar and oxygen. Since these functional changes take place before physical changes occur, PET can provide information that enables your physician to make an early diagnosis. The PET exam pinpoints metabolic activity in cells and the CT exam provides an anatomical reference. When these two scans are fused together, your physician can view metabolic changes in the proper anatomical context of your body. PET/CT offers significant advantages including more accurate localization of functional abnormalities, and the distinction of pathological from normal physiological uptake, and improvements in monitoring treatment. A PET/CT scan allows physicians to measure the body's abnormal molecular cell activity to detect cancer (such as breast cancer, lung cancer, colorectal cancer, lymphoma, melanoma and other skin cancers), brain disorders (such as Alzheimer's disease, Parkinson's disease, and epilepsy), and heart disease (such as coronary artery disease).

  • PDF

The Effect of $Ba^{2+}$ion Dissolution on Microstructural Changes and Electrical Properties in $BaTiO_3$ Aqueous Slurry System (나노 $BaTiO_3$ 수계슬러리에서 미세구조 및 전기적 특성에 미치는 $Ba^{2+}$이온 용출의 영향)

  • 김상우;신용욱;이해원;윤기현
    • Journal of the Korean Ceramic Society
    • /
    • v.37 no.5
    • /
    • pp.511-515
    • /
    • 2000
  • The effect of Ba2+ ion dissolution with different pH and amount of PAA on microstructural changes of green and sintered bodies and its electrical properties was studied in aqueous nano-size BaTiO3 slurry system. The dissolution of Ba2+ was least at strong base, pH 10.8 and by addition of amount of 0.15 wt% PAA. The green body with the lowest of dissolution of Ba2+ at pH 10.8 and 0.15 wt% PAA had minimum values of average pore size, 40nm and shown high increase of sintered density. The compact sintered at 125$0^{\circ}C$ for 2 hr with highest Ba2+ dissolution had low density and dielectric constant due to abnormal grian growth. However, the sintered body with the lowest Ba2+ dissolution had high sintered density and then shown high dielectric constant.

  • PDF

Three Months Subacute Toxicity of Water Soluble Dimethyl Dimethoxy Biphenylate Derivative in Rats (수용성 DDB 유도체의 3개월 반복투여독성에 관한 연구)

  • 신민기;손장원;김민영;방명주;김정현;최진혁;김준성;배미옥;문전옥
    • Toxicological Research
    • /
    • v.16 no.2
    • /
    • pp.151-161
    • /
    • 2000
  • The Three months subacute toxicity of water soluble dimethyl dimethoxy biphenylate derivative (DDB-S), newly formulated therapeutic agent for hepatitis, was invesgated in SD rats. The body weight and clinical signs were observed after intravenous injection of DDBs at doses of 57, 75 and 100 mg/kg/day for three months. Decrease in motor activity and tremor were observed above 75mg/kg treated groups. Statistically significant changes at serum biochemical analysis were found in some group, how-ever, those changes were within the normal range and had no relationship with dosage. There was no abnormal morphological and pathological findings in relation to DDB-S treatment. The no observable adverse effect level of DDB-S in rats was estimated to be 57 mg/kg/day in this study.

  • PDF

Growth and sex differentiation of children born small for gestational age (부당경량아에서의 성장과 성 발달)

  • Kim, Se Young
    • Clinical and Experimental Pediatrics
    • /
    • v.52 no.2
    • /
    • pp.142-151
    • /
    • 2009
  • The incidence of small for gestational age (SGA) births is frequent, accounting for 2.3% to 8% of all live births. Several childhood and adult diseases are related to early postnatal growth and birth size, and 10% of children born SGA may have a short stature throughout postnatal life. Additionally, they may have abnormal growth hormone (GH)-insulin like growth factor axis, HPA axis, and gonadal function. Permanent changes are detrimental in an environment of nutritional abundance, and predispose SGA children to an array of diseases in adolescence and adulthood. Such changes may also cause premature pubarche, adrenarche, and precocious puberty. The varying results from clinical studies necessitate more prospective case control studies. Reproductive tract abnormalities and reproductive dysfunction are related to SGA births. GH treatment is required for SGA infants who do not experience catch-up growth.

A study on deconstruction of costume based on Chaos Fractal Theory-Focused on analysis examples of costumes work- (카오스.프랙탈적 사고에 기초한 의상의 해체 경향에 관한 연구-작품사례 분석을 중심으로-)

  • 박현신
    • Journal of the Korean Society of Costume
    • /
    • v.38
    • /
    • pp.179-191
    • /
    • 1998
  • On this thesis, the focus is that studying costumes which have been affected by deconstructionism that is based on chaos and fractal the-ory. Chaos and fractal theory is accepted as a new paradigm for open world which is changing very vast and fast. And this theory is needed for artists and designers who should have spacetime conciousness and open mind and attitude towark open world. In the results, various costume typess of deconstructionism have been shown by fashion designers and artists' works. Thoes are as follows; 1. normal relationship of costume changes to abnormal relationship 2. three-dimentional structure of costume changes to two-dimentional structure. 3. open to materials and techniques. 4. separated costume parts reconstruct as ambiguous whole on function. 5. body absence and accessorizing.

  • PDF