• Current Optics and Photonics
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• 제2권4호
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• pp.324-331
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• 2018

This paper describes a symmetric method for determining a combination of element power and optical material to design a catadioptric system with corrected color aberration and flat Petzval curvature. To graphically obtain the solutions, a glass chart containing the Abbe number, the refractive index, and the optical power, which are closely related to these aberrations, is suggested. First, we recompose an optical system as a doublet of the specific lens and an equivalent single lens, and then locate both lenses on lines that are symmetric to each other on a glass chart, through changing the lens parameters effectively. Utilizing this method, an achromatic catadioptric system with flat Petzval curvature is obtained.

• 한국생물정보학회:학술대회논문집
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• 한국생물정보시스템생물학회 2006년도 Principles and Practice of Microarray for Biomedical Researchers
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• pp.125-126
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• 2006

NimbleGen has developed strategies to use its high-density oligonucleotide microarray platform (385,000 probes per array) to map both promoter binding sites and copy number variation at very high-resolution in the human genome. Here we describe a genome-wide map of active promoters determined by experimentally locating the sites of transcription imitation complex binding throughout the human genome using microarrays combined with chromatin immunoprecipitation. This map defines 10,567 active promoters corresponding to 6,763 known genes and at least 1,196 un-annotated transcriptional units. Microarray-based comparative genomic hybridisation (CGH) is animportant research tool for investigating chromosomal aberrations frequently associated with complex diseases such as cancer, neuropsychiatric disorders, and congenital developmental disorders. NimbleGen array CGH is an ultra-high resolution (0.5-50 Kb) oligo array platform that can be used to detect amplifications and deletions and map the associated breakpoints on the whole-genome level or with custom fine-tiling arrays. For whole-genome array CGH, probes are tiled through genic and intergenic regions with a median probe spacing of 6 Kb, which provides a comprehensive, unbiased analysis of the genome.

• 한국환경성돌연변이발암원학회:학술대회논문집
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• 한국환경성돌연변이발암원학회 2002년도 Current Trends in Toxicological Sciences
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• pp.124-124
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• 2002

• 한국컴퓨터정보학회논문지
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• 제23권2호
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• pp.1-7
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• 2018

The adaptive optics for compensating for optical wavefront distortion due to atmospheric turbulence has recently been used in systems that improve beam quality by eliminating the aberrations of high power laser beam wavefront. However, unseen-mode, which can not be measured in the wavefront sensor, increases the instability of the laser beam wavefront compensator on the adaptive optics system. As a method for improving such instability, a mathematical method for limiting the number of singular values is used when generating the command matrix involved in generation of the drive command of the wavefront compensator. In the past, however, we have relied solely on experimental methods to determine the limiting range of the singular values. In this paper, we propose a criterion for determining the limiting range of the singular values using the driving characteristics and the correlation technique of the wavefront compensator's actuators and have proved its performance experimentally.

• Journal of Plant Biology
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• 제33권3호
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• pp.189-196
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• 1990

Suspension cell lines have been newly established from the calli derived from the immuature embryo culture of hexapolid (Triticum aestivum var. sicco), tetrapolid (T. durum) and diploid (T. tauchii or Aegilops squarrosa) wheat species. The chromosomal variation in suspension cultured cell lines was examined and old cell line, C82d, established from T. aestivum var. copain was also used. New method using 1-bromonaphthalene for metaphase rapping of suspension cells was developed. Variation in chromosome number was observed among all the suspension lines. Cells with doubled chromosome number and deleted chromosome were also observed. Extensive structural changes in chromosome were found in C82d line. Chromosome aberrations showed loss of chromosome arms and chromosome segment. The mean chromosome number in suspension cells of T. aestivum var. sicco was 40, in C82d line 33, in T. durum 28 and in T. tauchii 14. The stability of chromosome in suspension cells of diploid and tetrapolid wheats was higher than that of hexaploid wheat.

• 한국광학회지
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• 제12권6호
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• pp.512-518
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• 2001

본 논문에서는 Head Mounted Display(HMD)용 광학계의 기하학적인 특징과 회절광학소자를 이용한 HMD용 광학계 설계의 개념에 대해 논의하였다. 사용자가 영상을 볼 때 편안함을 갖도록 HMD용 광학계는 경량화, 소형화 및 고해상도를 만족해야 한다. 이러한 요구조건들을 만족시키기 위해 본 논문에서는 회절광학소자와 양면 비구면화를 적용하여 색수차와 단색수차를 보정하였다. 또한 인간의 눈을 모델링하여 일반화한 모형안을 HMD용 광학계의 설계 및 성능평가에 적용하였다.

• Journal of the Optical Society of Korea
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• 제16권3호
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• pp.228-235
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• 2012

It is very important to analyze effectively the tolerance of an optical system with high resolution as the projection lens of photolithography or as the objective lens of a microscope. We would like to find an effective assembly structure and compensators to correct aberrations through global wavefront sensitivity analysis using Zernike polynomial expansion from the field and pupil coordinates rather than from only pupil coordinates. In this paper, we introduce global wavefront coefficients by small perturbations of the optical system, and analyze the optical performance with these coefficients. From this analysis, it is possible to see how we can enlarge the tolerance through the proper assembly structure and compensators.

• 약학회지
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• 제22권4호
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• pp.175-192
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• 1978

Chlorination of the polluted water may produce odoriferous and objectionable-tasting chlorophenols which are hazardous to health. These studies were undertaken to investigate the hazardous effects of chlorophenols to the rat. 1. The chlorophenols such as o-chlorophenol and 2,6-dichlorophenol inhibited rat growth and caused increment of the ratio between liver weight and body weight. 2. The hemoglobin content, hamatocrit ratio and A/G of rat blood were decreased by chlorophenols administration. The activities of alkaline phosphatase, lactic dehydrogenase (LDH) and glutamate oxaloacetate transaminase (GOT) in serum as well as in liver were increased provisonally and decreased after one or two weeks adminstration. 3. The liver mitochondrial respiration ($QO_{2}$) was inhibited by chlorophenols treatment in in-vivo and in-vitro test. 4. The liver microsomal cytochrome P-450 was decreased by chlorophenols administration 5. Liver tissue was degenerated with congestion, atrophy, swelling, vacuolation, dilation of rough endoplasmic reticulum and denature of mitochondrial particle with swelling, and cristal destruction by chlorophenols adminstration. 6. After one and two weeks of adminstration of chlorophenols to rat, the aberrations of bone marrow chromosome and inhibition of its mitosis were observed respectively.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 Techno-Fair 및 추계학술대회 논문집 전기물성,응용부문
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• pp.138-139
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• 2007

The use of conventional Twyman and Fizeau interferometers inevitably fails in testing high precision optics because of errors always existing in reference elements producing the reference wavefront. Therefore it is necessary to apply to this task the interferometers of a radically new type, which are able to produce perfect reference wavefront with the help of light diffraction by a small obstacle or pinhole. In this paper new theoretical approaches and schematics of point diffraction interferometers are considered in detail with paying attention to constructive reliability. Such interferometers do not use reference optical surfaces and readily provide adequate estimation of errors and aberrations value of 0.01 wavelengths.

• Journal of information and communication convergence engineering
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• 제11권2호
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• pp.139-146
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• 2013

This paper proposes a new spatial filtering approach for increasing the depth-of-field (DOF) of imaging systems, which is very useful for obtaining sharp images for a wide range of axial positions of the object. Many different techniques have been reported to increase the depth of field. However the main advantage in our method is its simplicity, since we propose the use of purely absorbing beam-shaping elements, which allows a high focal depth with a minimum modification of the optical architecture. In the filter design, we have used the analogy between the axial behavior of a system with spherical aberration and the transverse impulse response of a 1D defocused system. This allowed us the design of a ring-shaded filter. Finally, experimental verification of the theoretical statements is also provided.