• Journal of the Korean Institute of Telematics and Electronics
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• v.27 no.4
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• pp.598-603
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• 1990

This study evaluates the performance of an optical receiver for binary phase shift keying (BPSK) signals in the presence of short noise originating from the photo diode and phase noise of the optical source. The case of using I.O. hybrid compare with the fiber optic hybrid to mix received optical signal and laser local oscillator signal. The impact of these noise is minimized if loop natural frequency and power split ratio between data and carrier recovery branch are choosen optimally. Then it is obtained that required laser linewidt to achieve a BER of 10**-9. The results are the same except theat in case of using the fiber optic hybrid the required optical power is twice as much as the I.O. hybrid.

• BMB Reports
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• v.34 no.1
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• pp.85-89
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• 2001

Both topoisomerase $II{\alpha}$ and $II{\beta}$ east as phosphoproteins in the cells. Recently it was reported that DNA topoisomerase $II{\alpha}$ associates with and is phosphorylated by the extracellular signal-regulated kinase 2 (ERK2). Also, ERK2 stimulates the activity of topoisomerase II by a phosphorylation-independent manner [Shapiro et al., (1999) Mol. Cell. Biol. 19, 3551-3560]. In this study, a yeast two-hybrid system was used to investigate the binding site between topoisomerase $II{\alpha}$ or $II{\beta}$ and ERK2. The two-hybrid test clearly showed that topoisomerase $II{\beta}$ residues 1099-1263, and topoisomerase $II{\alpha}$ residues 1078-1182, mediate the interaction with ERK2, and that the leucine zipper motifs of topoisomerase $II{\alpha}$ and $II{\beta}$ are not required for its physical binding to ERK2. Our results suggest that topoisomerase $II{\beta}$ residues 1099-1263, and topoisomerase $II{\alpha}$ residues 1078-1182, may be common binding sites for activator proteins.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.18 no.7
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• pp.541-548
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• 2006

A hybrid ventilation system was introduced to predict the ventilation performance of the apartments. This ventilation system was composed of the natural supply-air inlet and the forced exhaust-air outlet. Analysis was conducted by CFD technique and was performed on three ventilating flow rates; 30, 60, $120m^3/h$. As the results, residents feel comfortable thermally for $60m^3/h$. In the case of $120m^3/h$, however, residents feel uncomfortable both thermally and in air currents. In this study the energy saving for space heating is also an important factor. In the case of whole region with $180m^3/h$, residents feel comfortable at each region of the model apartment. It is shown that this hybrid ventilation system is possible method for the apartment house.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2003.11a
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• pp.104-108
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• 2003

Finite element (FE) model updating is a procedure to minimize the differences between analytical and experimental results, which can be usually posed as an optimization problem. This paper aims to introduce a hybrid optimization algorithm (GA-SA), which consists of a Genetic algorithm (GA) stage and an Adaptive Simulated Annealing (ASA) stage, to FE model updating for a shrunk shaft. A good agreement of the first four natural frequencies has been achieved obtained from GASA based updated model (FEgasa) and experiment. In order to prove the validity of GA-SA, comparisons of natural frequencies obtained from the initial FE model (FEinit), GA based updated model (FEga) and ASA based updated model (FEasa) are carried out. Simultaneously, the FRF comparisons obtained from different FE models and experiment are also shown. It is concluded that the GA, ASA, GA-SA are powerful optimization techniques which can be successfully applied to FE model updating, the natural frequencies and FRF obtained from all the updated models show much better agreement with experiment than that obtained from FEinit model. However, FEgasa is proved to be the most reasonable FE model, and also FEasa model is better than FEga model.

• Journal of Microbiology and Biotechnology
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• v.15 no.5
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• pp.1039-1046
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• 2005

The salt resistance of antibacterial activity and synergistic effect with clinically used antibiotic agents are critical factors in developing effective peptide antibiotic drugs. For this reason, we investigated the resistance of antibacterial activity to antagonism induced by NaCl and $MgCl_2$ and the synergistic effect of P20 with cefotaxime. P20 is a 20-residue synthetic peptide derived from a cecropin A (CA)-melittin(ME) hybrid peptide. In this study, P20 was found to have potent antibacterial activity against clinically isolated methicillin-resistant Staphylococcus aureus (MRSA) strains without hemolytic activity against human erythrocytes. The combination study revealed that P20 in combination with cefotaxime showed synergistic antibacterial activity in an energy-dependent manner. We also confirmed the synergism between P20 and cefotaxime by fluorescence-activated flow cytometric analysis by staining bacterial cells with propidium iodide (PI) and bis-(1,3-dibutylbarbituric acid) trimethine oxonol (BOX). This study suggests that P20 may be useful as a therapeutic antibiotic peptide with synergistic effect in combination with conventional antibiotic agents.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.28 no.2
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• pp.146-153
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• 2004

A Promising new approach to achieve low pollutant emissions and improvement of flame stability is tested experimentally using a cyclone jet hybrid combustor employing both premixed and diffusion combustion mode. Three kinds of nozzle are tested for mixing enhancement of fuel and air. The LNG (Liquified Natural Gas) is used as a fuel. The combustor is operated by two methods. One is DC (Diffusion Combustion) mode generated swirl flow by air as general swirl combustor, and the other is HC (Hybrid Combustion) mode. The HC mode consists of diffusion jet flame of axial direction and premixed cyclone flame of tangential direction in order to stabilized the diffusion jet flame. The results showed that the flame stability of HC mode is significantly enhanced than that of DC mode through the change of mixing characteristics by modifications of fuel nozzle. In addition, the reductions of CO and NOx emission in HC mode, as compared with that for the DC mode, is large than about 50% in stable region. Also, even using the low calorific fuel as $CO_2$-blended gas, it is identified that the cyclone jet hybrid combustor has the high performance of flame stability.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.23 no.12
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• pp.828-835
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• 2011

The purpose of this study is to analyze and evaluate the 3 types of indoor ventilation methods such as natural, mechanical, and hybrid ventilation in high-rise building which is affected by stack effect and outdoor air pressure. For the evaluation of the ventilation capacity, CFD simulation was performed in a typical high-rise residential building. The results of the simulations are as follows: 1) Natural ventilation method is not enough to the regulation. 2) In case of mechanical ventilation, congested area is occurred but meets the regulation. 3) In case of hybrid ventilation with stack effect, all the areas of indoor meet the regulation and congested area is reduced. 4) In case of high-rise building, the differences of ventilation rate among houses in the building are not large because the mechanical ventilation is main factor.

• Korean Journal of Plant Taxonomy
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• v.49 no.2
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• pp.127-139
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• 2019

The purported four hybrid origins of Asplenium in Korea were tested based on morphological, cytological and DNA sequence data. Asplenium castaneo-viride, A. ${\times}$ uiryeongse, A. ${\times}$ montanus, and A. ${\times}$ kitazawae share several morphological characteristics with the Asian walking fern A. ruprechtii and related taxa as parents and show a sympatric distribution with the putative parents, raising the possibility of hybrid origins: A. castaneo-viride (A. ruprechtii and A. incisum), A. ${\times}$ uiryeongse (A. ruprechtii and A. pekinense), A. ${\times}$ montanus (A. ruprechtii, A. trichomanes, and A. incisum), and A. ${\times}$ kitazawae (A. ruprechtii and A. sarelii). We investigated flow cytometry and chloroplast DNA sequence data (rbcL, rps4-trnS, and rps4-trnS intergenic spacer) to clarify the hybridization and origin of each hybrid. In the flow cytometry analyses, A. ruprechtii shows diploid (2x) only, whereas A. castaneo-viride (3x, 4x), A. ${\times}$ uiryeongse (3x), A. ${\times}$ montanus (3x, 4x), and A. ${\times}$ kitazawae (2x, 4x) exhibit polyploidy, suggesting hybrid events along speciation. The rbcL and rps4-trnS and rps4-trnS intergenic spacer data suggest that A. ruprechtii is one the maternal ancestors of all four hybrids. In addition, the rps4-trnS and rps4-trnS intergenic spacer data indicate that A. incisum is also the maternal ancestor of A. ${\times}$ kitazawae and A. ${\times}$ montanus, proposing multiple hybridization events for these two hybrids. In A. ${\times}$ montanus, morphological features such as the leaf forms and sympatric distributions of the species also support the multimaternal hypothesis, but the morphological features of A. ${\times}$ kitazawae must be examined with consideration of hybrid events. To clarify the complex hybrid evolutionary lineages of the four Asplenium hybrids, further research with taxon sampling and molecular markers should be conducted.

• Korean Journal of Plant Taxonomy
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• v.41 no.4
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• pp.365-369
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• 2011

In this paper, a new hybrid species, Pulsatilla ${\times}$ yanbianensis H.Z. Lv, is named and described from the Yanbian area of Jilin Province in China. Molecular data confirm that this taxon is a result of natural hybridization between P. dahurica and P. cernua. As intermediate and mosaic phenotypes are expected for an interspecific hybrid, the leaves of P. ${\times}$ yanbianensis are fully expanded at the anthesis, resembling one of the parental species, P. daurica. However, the hybrid taxon is distinct from P. daurica by having reddish violet sepals and sterile fruits. Pulsatilla ${\times}$ yanbianensis also resembles the other parental species, P. cernua, in that it has dark red sepals and styles. The new hybrid, however, can be distinguished from P. cernua because it has leaf margins with short hairs and fully expanded leaves at the anthesis.

• Structural Monitoring and Maintenance
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• v.9 no.2
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• pp.179-200
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• 2022

This paper proposes a data-driven methodology for online early damage identification under changing environmental conditions. The proposed method relies on two data analysis methods: feature-based method and hybrid principal component analysis (PCA) and kernel PCA to separate damage from environmental influences. First, spectral sub-band features, namely, spectral sub-band centroids (SSCs) and log spectral sub-band energies (LSSEs), are proposed as damage-sensitive features to extract damage information from measured structural responses. Second, hybrid modeling by integrating PCA and kernel PCA is performed on the spectral sub-band feature matrix for data normalization to extract both linear and nonlinear features for nonlinear procedure monitoring. After feature normalization, suppressing environmental effects, the control charts (Hotelling T² and SPE statistics) is implemented to novelty detection and distinguish damage in structures. The hybrid PCA-KPCA technique is compared to KPCA by applying support vector machine (SVM) to evaluate the effectiveness of its performance in detecting damage. The proposed method is verified through numerical and full-scale studies (a Bridge Health Monitoring (BHM) Benchmark Problem and a cable-stayed bridge in China). The results demonstrate that the proposed method can detect the structural damage accurately and reduce false alarms by suppressing the effects and interference of environmental variations.