• Journal of Nutrition and Health
• /
• 제38권2호
• /
• pp.117-124
• /
• 2005

We investigated the effects of prolonged exposure in hot environmental condition and ingestion of fluid on various physiological variables including plasma glucose, lactate, the rating of perceived exertion (RPE), and heart rate as well as golf putting performance. Six male professional golfers were voluntarily participated in three different putting trials which were separated by seven days of time interval period. Three different putting trials were conducted at either 20℃ or 32℃, or 32℃ + Fluid ingestion. Performing 32℃ + Fluid ingestion trial, all subject ingested sport drink as much as their body mass was decreased. For each experiment, all subjects were undertaken total 48 putting, which separated by four x 12 putting in four different time points (i.e., Rest, 1 hr, 2 hr, and 3 hr). Plasma glucose concentration was significantly decreased with hot ambient condition but it was almost fully recovered by fluid ingestion. Plasma lactate concentration was significantly higher when subjects were exposed in hot environmental condition, and it did not change with fluid ingestion. There was a no different in putting performance and psychological fatigue level (performed by GRID test) at any environmental conditions. The RPE, commonly used for evaluating of physical fatigue level, was significantly dropped by fluid ingestion which indicates lower physical fatigue level. In addition to this, heart rate (HR) was also significantly decreased after fluid ingestion. Based on these results, it was concluded that the ingestion of fluid during prolonged exposure in hot ambient condition decrease the degree of physical fatigue levels and heart rate, which will possibly improve the golf performance when exposed in extreme weather condition in summer. (Korean J Nutrition 38(2): 117～124, 2005)

• 대한치과교정학회지
• /
• 제21권1호
• /
• pp.17-29
• /
• 1991

The purpose of this study was to provide quantitative data describing the effect of rapid palatal expansion (RPE) on nasal airway resistance (NAR). RPE is an orthopedic procedure which is commonly used to widen the maxilla in skeletal Class III patients. 18 subjects (9 males and 9 females, mean age: 10 years 7 months) were selected from the Orthodontics in Yongdong Severance Hospital. Recordings of NAR were taken by active anterior method prior to expansion, immediately after desired maximum expansion, and after approximately 3 months and 6 months, and 1 year. All data was recorded and statistically processed with the SPSS program of IBM PC system. The results are as followings . 1. The average initial NAR of the subjects was 3.84 cm $H_2O/LPS\;(SD{\pm}1.34)$. It was greater than the average NAR of the normal subjects. 2. Among 18 subjects, 9 subjects showed reduction of NAR and 9 subjects showed no specific change of NAR after expansion. 3 An average reduction in NAR after immediately expansion was statistically significant at the 0.05 level. 4. The reduction appeared stable throughout the post treatment observation period of 1 year after expansion. From these results, it was suggested that RPE is a useful method to reduce NAR.

• Molecules and Cells
• /
• 제43권7호
• /
• pp.632-644
• /
• 2020

The molecular mechanism underlying autophagy impairment in the retinal pigment epithelium (RPE) in dry age-related macular degeneration (AMD) is not yet clear. Based on the causative role of poly(ADP-ribose) polymerase 1 (PARP1) in RPE necrosis, this study examined whether PARP1 is involved in the autophagy impairment observed during dry AMD pathogenesis. We found that autophagy was downregulated following H₂O₂-induced PARP1 activation in ARPE-19 cells and olaparib, PARP1 inhibitor, preserved the autophagy process upon H₂O₂ exposure in ARPE-19 cells. These findings imply that PARP1 participates in the autophagy impairment upon oxidative stress in ARPE-19 cells. Furthermore, PARP1 inhibited autolysosome formation but did not affect autophagosome formation in H₂O₂-exposed ARPE-19 cells, demonstrating that PARP1 is responsible for impairment of late-stage autophagy in particular. Because PARP1 consumes NAD⁺ while exerting its catalytic activity, we investigated whether PARP1 impedes autophagy mediated by sirtuin1 (SIRT1), which uses NAD⁺ as its cofactor. A NAD⁺ precursor restored autophagy and protected mitochondria in ARPE-19 cells by preserving SIRT1 activity upon H₂O₂. Moreover, olaparib failed to restore autophagy in SIRT1-depleted ARPE-19 cells, indicating that PARP1 inhibits autophagy through SIRT1 inhibition. Next, we further examined whether PARP1-induced autophagy impairment occurs in the retinas of dry AMD model mice. Histological analyses revealed that olaparib treatment protected mouse retinas against sodium iodate (SI) insult, but not in retinas cotreated with SI and wortmannin, an autophagy inhibitor. Collectively, our data demonstrate that PARP1-dependent inhibition of SIRT1 activity impedes autophagic survival of RPE cells, leading to retinal degeneration during dry AMD pathogenesis.

• 한국응용과학기술학회지
• /
• 제37권4호
• /
• pp.699-710
• /
• 2020

본 연구는 복합운동이 여성노인의 폐기능, 혈중 비타민 D, 칼슘 및 골대사호르몬에 미치는 영향을 구명하기 위해 만 65세 이상 여성노인을 대상으로 운동군(n=13), 대조군(n=17)으로 구분하여 주 3회, 회당 60분의 복합운동을 실시하였다. 유산소 운동 강도는 1-4주는 40-50%HRR(RPE 12-13), 5-8주는 50-60%HRR(RPE 13-14), 9-12주는 60-70%HRR(RPE 14-15)의 강도로 설정하였고 저항 운동 강도는 1-4주는 OMNI-RES(3-4), 5-8주는 OMNI-RES(5-6), 9-12주는 OMNI-RES(7-8)강도로 설정하였다. 그 결과 폐기능 중 FEV₁은 그룹×시기 간 상호작용 효과가 나타났고 운동군의 FVC/FEV₁이 유의하게 증가하였다. 비타민 D는 그룹×시기 간 상호작용 효과가 나타났고, 운동군과 대조군 모두 유의하게 증가하였다. 칼슘은 그룹×시기 간 상호작용 효과가 나타났으며 대조군이 유의하게 감소하였다. 골대사호르몬 중 칼시토닌과 오스테오칼신은 그룹×시기 간 상호작용 효과가 나타났고, 오스테오칼신은 대조군이 유의하게 감소하였다. 따라서 본 연구의 결과를 통해 12주간의 복합운동이 여성노인의 신체활동을 활발하게 하여 폐기능을 개선하고 혈중 비타민 D의 결핍을 완화할 수 있다고 생각되지만 칼슘 및 골대사호르몬에서는 유의미한 결과를 나타내지 못하였다.

• PNF and Movement
• /
• 제18권3호
• /
• pp.315-321
• /
• 2020

Purpose: Recent studies have indicated that applying different inclination angles and suspension devices could be a useful way of performing exercises that include the co-activation of the trunk muscles. Present study was to examine the influences of changes in the inclination angle during trunk muscle activity while engaging in a bridge exercise with a suspension device. Methods: 18 healthy, physically active male volunteers completed three trunk inclination angles (15°, 30°, and 45°) for bridge exercise variations. The surface electromyography responses of the rectus abdominis, internal oblique (IO), erector spinae (ES), and rectus femoris (RF), as well as the subjective difficulty (Borg RPE score), were investigated during these bridge exercises. Results: The bridge with a 45° inclination angle suspension significantly increased the muscular activities of the RA and RF and increased the Borg RPE scores (p<0.05). The bridge with a 15° suspension significantly elevated the ES activities when compared to the other conditions. Conclusion: The present study demonstrated that a higher inclination angle could not activate the overall trunk muscles during the bridge exercise. The RA and RF produced greater activation during the bridge exercise with the higher inclination angle. On the other hand, the activities of the erector spine were greater during the bridge exercise with the lower inclination angle. The present study suggests that applying a low trunk inclination angle for the supine bridge exercise is suitable for activating the erector spine muscles.

• 한국운동역학회지
• /
• 제19권2호
• /
• pp.227-235
• /
• 2009

본 연구는 등산 폴 사용 여부와 걷는 지속시간 경과가 오르막 걷기에 미치는 영향을 규명하는 것이었다. 이러한 연구목적을 달성하기 위해 7명의 피험자가 동원되었고, 각 피험자들은 45분 동안 오르막 25%로 세팅된 트레드밀 위에서 3.5km/h의 속도로 폴 사용 여부에 따른 2회의 실험을 각각 수행하였다. 대퇴직근, 전경골근, 비복근, 대퇴이두근 등을 포함한 하지의 대표적인 4개 근육들에 대한 활동량이 EMG를 통해 획득되었고, 피험자의 심박수와 주관적 운동자각도가 15분 간격으로 기록되었다. 등산 폴 사용 여부와 걷는 지속시간이 경과됨에 따른 이러한 변인들의 통계적 유의성을 검증하기 위해 이원 급내 분산분석이 사용되었고, 이 때 통계적 유의수준은 P<.05로 설정하였다. 본 연구의 결과를 요약하면 다음과 같다 : 첫째, 4개의 개별 근육에 대한 적분근전도는 조건에 따라 통계적 차이가 나타나지 않았지만, 4개 근육을 합한 적분근전도는 폴을 사용한 경우가 사용하지 않은 경우보다 더 작게 나타났고, 시간 경과에 따른 차이점은 나타나지 않았다. 둘째, 심박수는 폴 사용 여부에 의한 차이는 없었지만, 걷는 지속시간이 경과됨에 따라 더 크게 나타났다. 셋째, 운동자각도의 경우, 폴을 사용했을 때가 그렇지 않았을 때보다 더 적게 나타났고, 걷는 지속시간이 경과됨에 따라 증가하는 것으로 나타났다.

• 한국응용과학기술학회지
• /
• 제36권2호
• /
• pp.456-467
• /
• 2019

본 연구는 고령여성을 대상으로 복합운동이 치매관련인자, 우울감 및 인지기능에 미치는 영향을 규명하기 위하여, 76-83세 고령여성을 대상으로 운동군 14명, 통제군 14명으로 분류하여 회당 90분씩 주 3회 탄력밴드 운동과 아쿠아로빅스를 16주간 실시하였다. 본 연구의 운동강도는 운동자각도를 설정하여 1-4주는 RPE 10-11, 5-16주는 RPE 11-14를 유지하였다. 복합운동 실시 전 후 측정한 자료의 그룹 내 차이는 대응표본 T검정, 그룹 간 차이는 독립표본 T검정, 상호작용 검증을 위해 이원배치 반복측정 분산분석을 사용하였으며, 각 항목별 통계적 유의수준은 .05로 설정하였다. 그 결과 운동군에서 ${\beta}-amyloid$(p<.01) 농도와 우울감(p<.001)이 유의하게 감소하였고, DHEAs(p<.01) 농도와 인지기능(p<.01)이 유의하게 증가하였다. 그러나 통제군은 유의한 차이가 나타나지 않았다. 이상의 결과 규칙적이고 지속적인 복합운동은 고령여성의 치매관련인자, 우울감 및 인지기능의 변화에 긍정적인 영향을 미친 것으로 사료된다.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• 제37권
• /
• pp.11.1-11.5
• /
• 2015

Rapid palatal expansion(RPE) with the tooth-born appliance is not sufficient to apply to the patients with periodontal problem or insufficient tooth anchorage, and it leads to tipping of the anchorage teeth and increasing teeth mobility and root resorption. To avoid these disadvantages, we present the case using palatal screws and custommade palatal expander. A 23-year-old patient underwent surgically assisted rapid maxillary expansion with the Hyrax expansion using 4 tent screws. The study models were used to measure the pre-/-post surgical width of the anterior and posterior dental arches with a digital sliding caliper. In the result, the custom-made palatal expander with 4 tent screws is suitable for delivering a force to the mid-palatal suture expansion. And it is low cost, small sized and simply applied. The results indicated that maxillary expansion with the custom-made palatal anchorage device is predictable and stable technique without significant complications in patients.

• Physical Therapy Rehabilitation Science
• /
• 제11권4호
• /
• pp.430-435
• /
• 2022

Objective: This study was conducted to investigate the effect of active movement with skin mobilization on range of motion, pain, and rating of perceived exertion in patients diagnosed with axillary web syndrome after axillary lymph node dissection. Design: A Case report Methods: It was performed on 7 patients diagnosed with axillary web syndrome after lymph node dissection. The subjects experienced a decrease in the range of joint motion and pain in movement when raising their arms in their daily lives, and complained of discomfort. The active range of motion, numeric rating scale, and modified Borg scale of shoulder joint flexion were measured, and the differences after active movement with skin mobilization were compared. Results: All subjects increased by 24.9 degree on average in active range of motion after active movement with skin mobilization intervention. There was no pain in the maximum range of joint motion measured before intervention, and rating of perceived exertion was significantly reduced. Conclusions: Active movement with skin mobilization can be a very useful way to help improve and treat axillary web syndrome, and it is recommended for improving the function and quality of life of axillary web syndrome patients. and It is also believed that it can be used steadily at home through the education of patients and families.

• 한국운동역학회지
• /
• 제20권3호
• /
• pp.303-310
• /
• 2010

The purpose of this study was (a)to compare electromyographic (EMG) activities and physiological variables on the development of fatigue induced by ergometer test, (b)to determine investigate the differences in the stage of fatigue between the electromyographic characteristics and physiological variables. Nine male university students who have no musculoskeletal disorder were recruited as the subjects. The electromyographic characteristics(peak IEMG, average IEMG, median frequency, mean edge frequency) and physiological variables(HR, RPE, blood lactate) were determined for each stage(15, 30, 45, 60 minutes, all out). For each dependent variable, one-way analysis of variance(ANOVA) with repeated measures and correlation analysis were performed to test if significant difference existed(p<.05). The results showed that peak IEMG, average IEMG from low extremity and physiological variables were significantly increased during the all-out stage. EMG parameters in VL, VM show significantly correlation with physiological variables during whole stages. This indicated that IEMG values may be proper parameters to determine muscle fatigue rather than physiological variables.