• Korean Chemical Engineering Research
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• v.50 no.5
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• pp.866-873
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• 2012

IgY (Immunoglobulin Yolk) is a specific antibody in egg yolk, and it protects human body from virus and antigen. There are a lot of egg yolk components such as lipoprotein and protein. To separate IgY, HPLC (High Performance Liquid Chromatography) and precipitation were used in a batch mode and SMB (Simulated Moving Bed) was adopted for continuous purification of yolk proteins. IgY and other proteins in yolk were separated by using three-zone and four-zone SMB chromatography. Before performing SMB experiments, batch chromatography simulation parameters and adsorption isotherms were obtained. The parameters of batch chromatography were used to simulate SMB using Aspen chromatography. To compare three-zone and four-zone SMB chromatography, simulations in $m_2-m_3$ plane on the triangle theory were carried out. In terms of concentration and purity of both IgY and other lipoproteins, 3-zone SMB process is considered as ideal at the vertex of triangle ($m_2$, $m_3$=0.1, 1.1). 4-zone SMB yields the highest IgY purity at the coordinate ($m_2$, $m_3$=0.06, 0.5), which is the pure raffinate region. In 3-zone SMB without recycle, other lipoproteins in extract are largely affected in purity by small shift from the vertex of triangle ($m_2$, $m_3$=0.1, 1.1).

• Journal of Food Hygiene and Safety
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• v.26 no.4
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• pp.361-365
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• 2011

To evaluate the indoor air quality of food manufacturing plants, the presence of viable bacteria and fungi was assessed in the indoor air of the facilities at which 9 food items were manufactured. Air samples were collected from the general zone, low clean zone and clean zone of each factory with an air sampler, in combination with plate counts agar using for bacteria, and dichloran-glycerol agar for fungi. The samples were incubated at $25^{\circ}C$ for 4 to 7 days. After culture, the colony forming units (CFU) on each plate were counted and corrected with a positive hole conversion table. The average concentration of bacteria was $2.2{\times}10^3\;CFU/m^3$ in the general zone, $1.2{\times}10^3\;CFU/m^3$ in the low clean zone and $7.3{\times}10^2\;CFU/m^3$ in the clean zone. The average concentration of fungal microbes was $2.5{\times}10^3\;CFU/m^3$ in the general zone, $2.6{\times}10^3\;CFU/m^3$ in the low clean zone, and $2.0{\times}10^2\;CFU/m^3$ in the clean zone. No meaningful differences were detected between the general zone and the low clean zone, but the clean zone had significantly lower concentrations than the other zones. Additionally, the identification of the fungi was performed according to morphological method using a giant culture and slide culture. The fungi were identified as belonging to 18 genera, and the genera Cladosporium(33%), Penicillium(29%) and Aspergillus(26%), predominated. Aspergillus isolates were identified to species level, and A. ochraceus, a mycotoxigenic species, was identified. As part of the effort to control the quality of the indoor air of food manufacturing plants, our results show that continued studies are clearly warranted.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.53 no.3
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• pp.161-167
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• 2004

Zone 3 of the distance relay is used to provide the remote back-up protection in case of the failure of the primary protection. However, the risk lot mal-operations under stressed conditions such as heavy loading, voltage and transient instability is usually high. Zone 3 is used in combination with the derivatives of the voltage, and current, etc to prevent mal-operations. Sometimes, the impedance characteristics that restrict the tripping area of relay are used to avoid the mal-operations due to load encroachment. This paper presents a novel Zone 3 scheme based on combining the steady-state components (i.e. 60Hz) and the transient components (TCs) using a state diagram that visualizes the sequence of studies that emanate from the sequence of events. The simulation results show that the novel zone 3 distance relay elements using the proposed method operates correctly for the various events.

• Journal of Acupuncture Research
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• v.25 no.6
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• pp.67-76
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• 2008

Objectives : The 7-zone-diagnostic system is a diagnostic device to predetermine bodily locations by measuring the energy of body. This study was to investigate the relation between the different patterns of Zone 1, 2, 3 of Factor AA in CP-6000A(VEGA, Germany), 7-zone-diagnostic system and clinical parameters. The purpose of this study was relation Korean traditional medicine and western medicine with the data from 7-zone-diagnostic system and the clinical parameters. Methods : This study was carried out with the data from some clinical parameters. We made three groups according to the Factor AA patterns of CP-6000A. The Factor AA pattern of Group A is that the red bar graph of zone 1, 2, 3 were higher than the normal range and the others were the normal range. The Factor AA pattern of Group B was that the red bar graph of zone 1, 2, 3 was the normal range and the others were the normal range. The Factor AA pattern of Group C was that the red bar graph of zone 1, 2, 3 was lower than the normal range and the others were the normal range. After the data from clinical parameters to correspond with conditions of each group were selected, the data from clinical parameters among each groups analyzed statistically. Results : The values of GOT, GPT, r-GPT, Triglyceride, BUN, Uric acid of group A was higher than group C. Gastroscope of group A and B was higher than group C. Conclusions : It is thought that the red bar graph of zone 1, 2, 3 is higher, the group has the higher energy and the energy has a character of fire(熱). Those patterns have a high risk of hyperlipermia and liver, stomach disease.

• Transactions on Electrical and Electronic Materials
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• v.3 no.2
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• pp.24-27
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• 2002

The NdBaCuO superconductor samples were zone-melted in low oxygen partial pressure (1%O$_2$+99%Ar). The zone-melting temperature was decreased about 12$0^{\circ}C$ film 1,06$0^{\circ}C$, the zone-melting temperature in air. Thus the loss of liquid phase (BaCuO$_2$ and CuO) was reduced during: the zone-melting process. The content of non-superconducting phase Nd422 in zone-melted NdBaCuO samples was clearly decreased and, therefore, the substitution of Nd for Ba was occurred. The superconductivity of zone-melted Nd$_{1+x}$Ba$_{2-x}$Cu$_3$O$_{y}$ prepared under low oxygen partial pressure was distinctively improved.d.d.d.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.4
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• pp.183-193
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• 2008

Purpose: To research the changes of Skin Resistance Variability(SRV) over the period of ovarian cycle of healthy young women with normal and regular menstrual cycles using Oriental Medical Diagnose Autonomic system-3000 (OMD-3000). Methods: We measured SRV of 15 women who were working at O O Oriental Hospital from July to Oct. 2008. Each woman took the OMD-3000 test 8 times during 2 menstrual cycles. Each cycle consists of 4 phases-follicular phase, ovulation, luteal phase and menstruation. We analyse the data by SPSS 12.0 for windows. the one-way ANOVA by Repeated Measure(p<0.05). Results: 1. (1) The Factor AA means at zone 1 were 0.77$\pm$0.40, at zone 2 were 1.07$\pm$0.68, at zone 3 were 0.77$\pm$0.35, at zone 4 were 0.68$\pm$0.32, at zone 5 were 0.74$\pm$0.29, at zone 6 were 0.85$\pm$0.30, and at zone 7 were 0.74$\pm$0.29. The Factor AA means were lower than normal range at zone 1,3,4,5,6 and 7. The graph pattern of M shape was caused by the Factor AA means at zone 2 and zone 6 were higher than others. (2) The Factor AA means at zone 1 and zone 3 show abnormal regulation state. 2. During the menstruation. the Factor AA means were higher at zone 1,2 and 3 than other zones. During the ovulation, the Factor AA means were higher at zone 4,5,6 and 7 than other zones. Especially at the menstruation phase in zone 2 and at the ovulation phase in zone 6 tend to be highest means than other phases respectively. 3. However there were no significant difference of means during 4 ovarian phases in 7 zones except ovulation phase to luteal phase at zone 4(p = 0.013). Conclusion: The results suggest that changes of SRV during 4 menstrual cycles are not variables in reading 7-zone-diagnostic system. Further study will be needed.

• Electrical & Electronic Materials
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• v.7 no.2
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• pp.130-137
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• 1994

Indium, element of group III, was refined by using zone refining for high purity refinement. We have found the impurities of T1, Zn, Fe, Cd, Pb, Ni, Cu, Sn in the refined indium with ICP-AES, so that 3.9 weight ppm of T1 was reduced to less than 1 ppm, 1.0 weight ppm of Zn was reduced to 0.7 ppm, 2.8 weight ppm of Cd was reduced to 2.5 ppm and 14.0 weight ppm of Sn was reduced to 6.7 ppm with 5 melten zone passes only. 3.9 weight ppm of T1 was reduced to less than 1 ppm, 1.0 weight ppm of Zn was reduced to 0.3 ppm, 2.8 weight ppm of Cd was reduced to less than 1.0 ppm and 14.0 weight ppm of Sn was reduced to 0.4 ppm after vacuum baking with 5 melten zone passes. The surface morpholgy of metal Indium thin film in each conditions showed that porosities were reduced in the front of sampled ingot after vacuum baking with 5 zone melten zone passes. The average electrical resistivity of Indium thin film was reduced from 1.4*10$^{-3}$ .ohm.-cm in Indium origin ingot to 7.9*10$^{-6}$ .ohm.-cm after zone refined with 5 melten zone passes.

• Proceedings of the KIEE Conference
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• 2003.11a
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• pp.245-247
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• 2003

Zone 3 of the distance relay is used to provide the remote back-up protection in case of the failure of the primary protection. However, the risk for mal-operations under stressed conditions such as heavy loading, voltage and transient instability is usually high. Zone 3 is used in combination with the derivatives of the voltage, and current, etc to prevent mal-operations. Sometimes, the impedance characteristics that restrict the tripping area of relay are used to avoid the mal-operations due to load encroachment. This paper presents a novel zone 3 scheme based on combining the steady-state components(i.e. 60Hz) and the transient components(TCs) using a state diagram that visualizes the sequence of studies that emanate from the sequence of events. The simulation results show that the novel zone 3 distance relay elements using the proposed method operates correctly for the various events.

• Journal of Environmental Science International
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• v.18 no.5
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• pp.561-567
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• 2009

The distribution of benthic macroinvertebrates of Shinbulsan wetland was investigated. This study was focused on the degree of recovery of habitat by comparing the community structure of benthic macro invertebrates of zone D to that of zone A, intact habitat. The zone D was destructed due to the construction of a golf club and the survey was performed in zone A and zone D of Shinbulsan wetland. The seasonal survey was performed in April, July and September from 2006 to 2007. From the sampling, 2 phyla, 3 classes, 9 orders, 31 families, 69 species and 1155 individuals of benthic macroinvertebrates were collected. From zone A, 2 phyla, 3 classes, 9 orders, 23 families, 54 species and 678 individuals were identified. From zone D, 2 phyla, 3 classes, 9 orders, 23 families, 43 species and 477 individuals were identified. Species diversity and species richness were higher in zone A than in zone D. The recovery of zone D was inefficient as humidity of soil was not enough to live macroinvertebrates. Also, an endangered species of macroinvertebrates, Nannophya pygmaea was found during this investigation.

• Economic and Environmental Geology
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• v.41 no.2
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• pp.183-199
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• 2008

This study is focused on characterization of the physio-chemical and mineralogical properties, investigation of their vertical changes in the tailing profile of the Guryoung mining area, classification of the profile into distinct zones, and condition conceptual model of physio-chemical conditions and phases-water relationships controlling the element behaviors in the tailings. The upper part of the groundwater is characterized by the high contents of $Fe_2O_3$ and $SO_3$ for whole rock analysis, low pH, and the occurrence of jarosite, schwertmannite and Fe-oxyhydroxide as the secondary mineral phases. The tailing profile can be divided into the covering soil, jarosite zone, Fe-sulfate zone, Fe-oxyhydroxide and gypsum-bearing pyrite zone, calcite-bearing pyrite zone, soil zone, and weathered zone on the based of the geochemical and mineralogical characteristics. The profile can be sampled into the oxidized zone and the carbonate-rich primary zone with the dramatic changes in pH and the secondary mineral phases. The conceptual model proposed for the tailing profile can be summarized that the oxidation of pyrite is the most important reaction controlling the changes in pH, the dissolution of the primary silicates and carbonates, the precipitation of secondary mineral phases, acid-neutralizing, and heavy metal behaviors through the profile.