• Molecules and Cells
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• 제44권5호
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• pp.342-355
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• 2021

The microphthalmia-associated transcription factor family (MiT family) proteins are evolutionarily conserved transcription factors that perform many essential biological functions. In mammals, the MiT family consists of MITF (microphthalmia-associated transcription factor or melanocyte-inducing transcription factor), TFEB (transcription factor EB), TFE3 (transcription factor E3), and TFEC (transcription factor EC). These transcriptional factors belong to the basic helix-loop-helix-leucine zipper (bHLH-LZ) transcription factor family and bind the E-box DNA motifs in the promoter regions of target genes to enhance transcription. The best studied functions of MiT proteins include lysosome biogenesis and autophagy induction. In addition, they modulate cellular metabolism, mitochondria dynamics, and various stress responses. The control of nuclear localization via phosphorylation and dephosphorylation serves as the primary regulatory mechanism for MiT family proteins, and several kinases and phosphatases have been identified to directly determine the transcriptional activities of MiT proteins. In different immune cell types, each MiT family member is shown to play distinct or redundant roles and we expect that there is far more to learn about their functions and regulatory mechanisms in host defense and inflammatory responses.

• 한국의류학회지
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• 제47권4호
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• pp.593-608
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• 2023

This study attempted to classify the types of perceptions of the new Hanbok, focusing on female college students in their 20s, and to analyze the characteristics of each type. This study was conducted with the Q methodology and analyzed with the QUANL pc program. The perceptions of the new Hanbok among female college students in their 20s were classified into four types: Type 1: modern/practical, Type 2: convenient/practical, Type 3: temporary/accessible, and Type 4: convenient/traditional. Type 1 emphasized the selection of Western clothing fabric, matching zipper/buttons, and achromatic colors. Type 2 highlighted a design that can be worn as daily clothing by combining materials that are convenient for laundering. Type 3 stressed the operation of new Hanbok rental stores so that it is easy to access and accept new Hanboks in old palaces and Hanok villages. Type 4 required the development of a design that reflects the elements of the traditional Hanbok and is convenient for activity and laundering.

• 한국의류학회지
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• 제46권4호
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• pp.624-637
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• 2022

The purpose of this study was to develop a compression inner layer (CIL) that can be attached to dress shirts for men who have gynecomastia (male breast enlargement). For this, we developed shirts with CIL prototypes based on the functional, expressive, and aesthetic (FEA) consumer needs model. The user-centered design principle guided the design process. Based on size measurements, in-depth interviews, and an online survey, the design requirements for dress shirts with a CIL were determined, and the prototype was developed. The dress shirts were constructed of polyester and spandex mixed materials, while the CIL was made of thin mesh fabric knitted from 80% polyester and 20% spandex. A CIL prototype was developed with a front zipper fastening to hold the upper body tight and compress the breast area. The CIL was attached by connecting a strap with snap buttons to loops sewn into the shoulder line of the dress shirt. In the trial and sensory test, the prototype helped breast size decrease while meeting target consumer needs. The outcomes of this study provide necessary insights to develop garments for gynecomastia patients.

• 한국의류산업학회지
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• 제20권3호
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• pp.266-278
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• 2018

This study investigated the transformation of the Chanel jacket by looking at clothing design and constructional components. This study explored Chanel jacket's designs from 2001 S/S to 2016-17 F/W, and collected designs from Samsung Design Net and Vogue. The study used 690 designs with the following results. First, in the silhouette of the Chanel jacket, straight silhouette and hourglass silhouette had the most; in addition, in the length, hip line and under hip line were in order. Second, in case of collar and neckline, the form of a non-collar was the most and revealed the persistence of round neckline which is the basic style of a Chanel jacket. Third, in the shape of sleeves, the loose-fit straight sleeves, wide sleeves, and cocoon sleeves appeared most often. In method of closure, button, zipper were in order, and snaps or without closure appeared. Fourth, in the form of braids, various forms such as twisted yarns, leashes, or lace were used, and patch pockets were mainly used in pockets. Chanel maintains its original design by using various methods. Chanel tried to improve activity and functionality through silhouettes, lengths, necklines, and sleeves. The unchanging expression of the world of Chanel will continue to display and inherit future value. This study can provide Chanel's unique characteristics and new ideas that can transform their origins for jacket design.

• BMB Reports
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• 제51권8호
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• pp.388-393
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• 2018

The activating transcription factor (ATF) 4 belongs to the ATF/CREB (cAMP Response Element Binding bZIP [Basic Leucine Zipper]) transcription factor family, and plays a central role in the UPR (Unfolded Protein Response) process in cells. The induction of ATF4 expression has previously been shown to increase the replication of HIV-1. However, the detailed mechanism underlying this effect and the factors involved in the regulation of ATF4 function are still unknown. Here, we demonstrate first that knocking out ATF4 using siRNA shows a strong negative effect on HIV-1 production, indicating that ATF4 is a functional positive cellular factor in HIV-1 production. To determine the mechanism by which ATF4 regulates the HIV-1 life cycle, we assessed the effect of the overexpression of wild type ATF4 and its various derivatives on HIV-1 LTR-mediated transcriptional activation and the production of HIV-1 particles. This effect was studied through co-transfection experiments with either reporter vectors or proviral DNA. We found that the N-terminal domains of ATF4 are involved in HIV-1 LTR-mediated transcriptional activation, and thus in HIV-1 production.

• 한국의류산업학회지
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• 제17권5호
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• pp.781-792
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• 2015

This study aims to develop a spring/fall motorcycle jacket for quick service transporter. Depending on the results of the previous research, this study produced the tested jacket which was improved in material, pattern, and design. For the tested jacket, 100% polyester fabric excellent in strength, durability and abrasion-resistance was selected as a major material, and Cordura was used as a partial material to improve the strength and abrasion-resistance of the sleeve side lines, elbow and shoulder areas. The retro-reflection material was applied partially in order to improve visibility of the jacket in the night or in a dark place. A total of 7 pockets were composed in the jacket for the sufficient storage spaces. The functional design elements such as the 2-way zipper and the placket at the center front, the action pleats at the upper part of back armholes, the pit-zip at armpit were applied. In addition, the sleeve pattern was bent with the shape of elbow curvature in time of driving and the back length of the jacket was lengthened 4cm. As a result of the appearance assessment, there was a significant difference from the existing jacket in all items but chest size, shoulder width, cuffs circumference, and jacket hemline circumference. In motion adaptability and field activity appropriateness assessments, the assessment grade for all items was found to be commonly higher than that of the existing jacket, and thus, the tested jacket was assessed to be suitable for a motorcycle jacket design for the quick service transporters.

• 전자공학회논문지CI
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• 제43권6호
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• pp.92-100
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• 2006

디지털 카메라와 같은 장치에서 사용하는 단일 영상 센서는 화소 당 삼원색 중 하나의 색상만을 가진 서브샘플된 영상을 제공한다. 이 영상은 색상 보간이라는 영상 처리를 통해 완전한 색상 영상으로 복원된다. 본 논문에서는 영상 센서로부터 획득한 데이터의 평균과 각 색 채널 데이터 평균 사이의 관계를 유도하고, 이 관계를 이용하여 색상 보간을 위한 효율적인 새로운 방법을 제안하였다. 유도한 데이터 평균 관계는 채널간의 색상차가 지역적으로 균일하다는 가정을 이용하였다. 또한 휘도신호 채널의 보간은 지퍼 효과를 감소시키기 위해서 에지 방향을 따라 보간 하였다. 한편 색상신호 채널은 휘도신호 채널과의 차를 평균하고, 이 평균값을 보간할 위치의 색상 값에 더하여 복원하였다. 본 논문에서는 제안한 방법을 기존의 방법들과의 비교 실험을 통해 제안한 방법의 우수함을 입증하였다.

• 복식문화연구
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• 제15권5호
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• pp.796-809
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• 2007

The viewpoint of growth pursuit is changed to that of life quality's and happiness' pursuit by modern people. Modern people in digital environment, tired of fast-changing and oppressive daily life, prefer well-being trend providing tranquility and relaxation. Well-being is related to digital, because negative influences of digital lead human-oriented, environment-friendly well-being design. Therefore the purpose of this study is to research and analyze the relation of well-being fashion design and digital environment through case study in contemporary well-being fashion design. The results of this study are as follows: 1. This study shows that the attributes of digital environment make up function-intensive, interactivity, mobility & nomad, human & emotion-oriented and environment-friendly. And this study shows the design characteristics of digital environment consist of function-intensive design by digital convergence, open structure design for interactivity, modular design for mobility & nomad, emotion-oriented & multi-sensory design and environment- friendly design. 2. Function-intensive design in modem well-being fashion composed of vogue of caports style(casual+sports), practical use of multi-functional new-healthy textiles, and popularity of many style's mixture at once. Open structure design consist of wrapover design, use of transparent materials. Modular design are layered styling, practical use of zipper and velcro. Emotion-oriented & multi-sensory design are constitute of fad of wrinkle materials, application of bright & vivid tone, personal color and family look. Environment-friendly design in contemporary well-being fashion are comprised in use of natural color, re-advent of natural floral motif and eco-design.

• 지역사회간호학회지
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• 제19권3호
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• pp.398-407
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• 2008

Purpose: The purpose of this study was to examine the association among change in the sensation of the arms, the range of motion in the shoulders and depression in breast cancer patients. Method: This is a descriptive study on correlation. The participants were 132 patients who had been diagnosed with breast cancer and had mastectomy at a university hospital, and had participated in a breast cancer self-help group. The degree of depression was assessed by SCL-90-R scores. Collected data were analyzed with SPSS 12.0 for windows. Results: The participants complained of 'heaviness' as the most frequent and serious symptom of change in the sensation of the arms. 'Completely zip up the dress with a back-fastening zipper' was the most difficult motion of the shoulders. Participants who were in a worse stage of disease were in a worse condition in shoulder functions, and on a higher degree of depression. The degree of change in sensation and shoulder functions showed a positive correlation with each other, and both of them showed a negative correlation with the degree of depression. Conclusion: Sensation and motion change in the arms and the shoulders were common phenomena that affected depression in patients who had mastectomy. Nurses should consider not only depression but also discomfort of the arms and the shoulders for patients with mastectomy.

• 한국의류학회지
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• 제33권8호
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• pp.1227-1240
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• 2009

This study examines the actual conditions of toddler playwear preference survey for design and function. The study develops proper indoor and outdoor playwear for toddlers based on the analysis. A survey of 200 parents with toddlers between 2 and 6 years old and 120 teachers was conducted to find the conditions and needs for playwear along with the necessary design elements. Second, 6 designs including 3 designs for indoor playwear and 3 designs for outdoor playwear were made. These designs emphasized on soil contamination part, color, pattern, form, material, detail, and fasteners. Art play and cooking play are considered for indoor playwear and ways to decrease contamination on sleeve hem, elbow, chest, and knee were determined through the use of yellow, green, and blue colors. Applying a character and separate top with sleeves were determined. Light with breathable and waterproof fabric was determined. The correct amount of Velcro fasteners or buttons was determined for front fastening in addition a pocket was considered necessary as a detail part. The common design for both boys and girls along with a proper design for diverse play were determined. For outdoor playwear, water play, sand play, movement play, and ecology experience are considered and ways to decease contamination on hip, sleeve hem, and knee should be applied to the design as determined through the use of yellow, green, blue, and red colors. The demands for pattern, form, material, and details were similar to indoor playwear. Zipper and buttons for front fastening were determined. These final 6 playwear designs are presented using CAD WALK DESIGNWARE.