• Journal of Animal Science and Technology
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• v.55 no.5
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• pp.475-481
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• 2013

The objective of this study was to investigate the effect of red ginseng extracted with water extract (WE) and 50% ethanol extract (EE) from white ginseng on cooked meat patties during storage. Different concentrations of extracts were examined (0.25%, 0.5%, and 1.%, respectively, dry base w/w). A significantly higher water holding capacity (WHC) was observed in samples supplemented with ${\geq}$ 0.5% WE (p < 0.01); however, EE had no significant effect on the WHC of meat patties. Samples supplemented with ${\geq}$ 0.5% WE or EE showed a significantly higher redness ($a^*$-value) compared to the control (p < 0.01). The total plate counts (TPC) and 2-thiobarbituric acid-reactive substances (TBARS) of all treated samples were lower than those of the control. However, there were no significant differences in volatile basic nitrogen (VBN) values and sensory evaluation scores between the samples. These results suggest that red ginseng extract improves color and inhibits lipid oxidation and bacterial population at doses > 0.25%, prolonging the shelf-life of meat products and acting as a natural colorant.

• Journal of Fashion Business
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• v.11 no.5
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• pp.35-50
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• 2007

The purpose of this study was to investigate the result of a market research on men's jacket in their age of 25 to 35, who wear fitted jackets most, and to examine the comparative analysis of pattern and the wearing evaluation between classic jacket and fitted jacket. The results are as follows; Firstly, according to the results of a market research, 32.0% of the target owned fitted jackets, and 28.7% expressed their desire to buy only fitted jackets. This means their concern and preference for fitted jacket with which they could show up young, fresh and slim look are as high as those for classic jacket. Secondly, classic jacket showed the higher value than fitted jacket in such items as chest girth, waist girth, hip girth, sleeve's hem girth, jacket length, shoulder length, side seam length, and across shoulder point length. On the other hand, fitted jacket showed the higher value than classic jacket in back armhole length, front length, collar point length and sleeve's vent length. Thirdly, classic jacket was larger than fitted jacket in 1/2 chest girth(1.0cm), 1/2 waist girth(2.0cm), 1/2 hip girth(1.0cm), back width(0.5cm), front width(0.5cm) and side width(1.0cm). However, fitted jacket was higher than classic jacket in the armhole depth(0.5). Fourthly, the results of appearance evaluation revealed that there was a significant difference in 6 items. In other words, classic jacket was evaluated more appropriate than fitted jacket in such items as back width, back length, back neck depth, chest girth, waist girth and hip girth. And the fitted jacket had a higher value than the classic jacket in shoulder angle item. Fifthly, In the functional evaluation, fitted jacket was evaluated more uncomfortable than classic jacket. And this means that fitted jacket doesn't have a proper ease amount in each part and it has a high armhole depth compared to classic jacket. Therefore, for more comfortable patternmaking of fitted jackets, it would be required a pattern design which reflect men's own shoulder lines and women designers' flexibility that will satisfy both appearance and function.

• Journal of the Korean Society of Marine Environment & Safety
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• v.13 no.4
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• pp.15-19
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• 2007

Mass mortalities of the farmed sea squirt, Halocynthia roretzi, occurred in August, 2006 along the Gyeongbuk coasts of the East Sea without any pathological symptom. Suspecting the No. 10 typhoon, Wukong, which had passed over the relevant locations in the middle of August, 2006 as a culprit of the mortalities, we compared water temperature stratifications of the affected coasts before and after the typhoon. Just prior to the typhoon, cold waters lower than $15^{\circ}C$ were stratified at depths deeper than 10m probably by a persisting upwelling of cold bottom waters. The typhoon enforced water off-coast waters into coasts for 5 days, replacing the cold waters at depths $10{\sim}20m$ which can be justified by Ekman Spiral Effect. The results were an increment of water temperature by $10^{\circ}C$ and more at depths where sea squirts were suspended. The sudden elevation of water temperature might drive the sea squirts under abnormal stress to mass mortality.

• Korean Journal of Psychosomatic Medicine
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• v.10 no.1
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• pp.48-54
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• 2002

Objectives : Aims of the study were to investigate the physical and mental symptom profiles related with perceived life stress in normal populations. Methods: The study subjects were 186 subjects who visited the Health Promotion Center at National Health Insurance Corporation Ilsan Hospital between July and December, 2000. We measured Life Stress Assessment Scale (LSAS), SCL-90-R (Symptom Check List-90 Revised), and Physical Health Check Questionnaires to evaluate perceived life stress for one year, and physical and mental symptoms. The physical markers related with stress were also measured. According to LSAS scores, we selected two groups from all subjects : Group I (LSAS score with lower 25 percentile) and Group II (LSAS score with higher 75 percentile). Each number of subjects was 46 in Group I and 47 in Group II. We analyzed stasistical significances of study variables between Group I and II. Results : Group II subjects showed higher scores in all subscales of SCL-90-R compared to Group I subjects. Comparing to Group I, Group II subjects complained more physiological symptoms related with anxiety and depression. But there were no statistical differences in the physical markers related stress between two groups. Conclusion: We found that past year-life stress caused various mental and physical symptoms, which didn't develop any physical illness related life stress in normal populations yet.

• The Korean Journal of Physiology and Pharmacology
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• v.15 no.1
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• pp.1-7
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• 2011

Many anticancer agents as well as ionizing radiation have been shown to induce autophagy which is originally described as a protein recycling process and recently reported to play a crucial role in various disorders. In HCT116 human colon cancer cells, we found that curcumin, a polyphenolic phytochemical extracted from the plant Curcuma longa, markedly induced the conversion of microtubule-associated protein 1 light chain 3 (LC3)-I to LC3-II and degradation of sequestome-1 (SQSTM1) which is a marker of autophagosome degradation. Moreover, we found that curcumin caused GFP-LC3 formation puncta, a marker of autophagosome, and decrease of GFP-LC3 and SQSTM1 protein level in GFP-LC3 expressing HCT116 cells. It was further confirmed that treatment of cells with hydrogen peroxide induced increase of LC3 conversion and decrease of GFP-LC3 and SQSTM1 levels, but these changes by curcumin were almost completely blocked in the presence of antioxidant, N-acetylcystein (NAC), indicating that curcumin leads to reactive oxygen species (ROS) production, which results in autophagosome development and autolysosomal degradation. In parallel with NAC, SQSTM1 degradation was also diminished by bafilomycin A, a potent inhibitor of autophagosome-lysosome fusion, and cell viability assay was further confirmed that cucurmin-induced cell death was partially blocked by bafilomycin A as well as NAC. We also observed that NAC abolished curcumin-induced activation of extracelluar signal-regulated kinases (ERK) 112 and p38 mitogen-activated protein kinases (MAPK), but not Jun N-terminal kinase (JNK). However, the activation of ERK1/2 and p38 MAPK seemed to have no effect on the curcumin-induced autophagy, since both the conversion of LC3 protein and SQSTM1 degradation by curcumin was not changed in the presence of NAC. Taken together, our data suggest that curcumin induced ROS production, which resulted in autophagic activation and concomitant cell death in HCT116 human colon cancer cell. However, ROS-dependent activation of ERK1/2 and p38 MAPK, but not JNK, might not be involved in the curcumin-induced autophagy.

• Journal of Microbiology and Biotechnology
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• v.25 no.7
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• pp.1170-1176
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• 2015

Ginsenosides, the major active component of ginseng, are traditionally used to treat various diseases, including cancer, inflammation, and obesity. Among these, compound K (CK), an intestinal bacterial metabolite of the ginsenosides Rb₁, Rb₂, and Rc from Bacteroides JY-6, is reported to inhibit cancer cell growth by inducing cell-cycle arrest or cell death, including apoptosis and necrosis. However, the precise effect of CK on breast cancer cells remains unclear. MCF-7 cells were treated with CK ($0-70{\mu}M$) for 24 or 48 h. Cell proliferation and death were evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and flow cytometry assays, respectively. Changes in downstream signaling molecules involved in cell death, including glycogen synthase kinase $3\beta$ ($GSK3\beta$), $GSK3\beta$, $\beta$-catenin, and cyclin D1, were analyzed by western blot assay. To block $GSK3\beta$ signaling, MCF-7 cells were pretreated with $GSK3\beta$ inhibitors 1 h prior to CK treatment. Cell death and the expression of $\beta$-catenin and cyclin D1 were then examined. CK dose- and time-dependently inhibited MCF-7 cell proliferation. Interestingly, CK induced programmed necrosis, but not apoptosis, via the $GSK3\beta$ signaling pathway in MCF-7 cells. CK inhibited $GSK3\beta$ phosphorylation, thereby suppressing the expression of $\beta$-catenin and cyclin D1. Our results suggest that CK induces programmed necrosis in MCF-7 breast cancer cells via the $GSK3\beta$ signaling pathway.

• Journal of Korean Ophthalmic Optics Society
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• v.18 no.4
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• pp.555-560
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• 2013

Purpose: The aims of this study were to investigate the stereoacuity and subjective symptoms of aniseikonia with prescription of the size lens. Methods: Participants were myopic anisometropia patients with the binocular refraction difference between 1.75 D~3.50 D. Inclusion criteria of participants were no ocular pathology, no amblyopia, more than 1.0 of corrected visual acuity. With fully corrected spectacles and a correction with the size lens, Awaya aniseikonia test and Randot Stereo test were conducted respectively. In addition, subjective symptoms were also examined using questionnaire. Results: As the anisometropia increased, the aniseikonia increased. Under the anisometropia with same refractive correction was different for each individual. The prescription of size lens caused less aniseikonia than the general prescription of glasses. In addition, prescription of the size lens improved stereoacuity and relieved the symptoms of asthenopia. Conclusions: The prescription of size lens that can correct aniseikonia with prescription of glasses can improve stereoacuity and reduced asthenopia.

• Journal of Advanced Navigation Technology
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• v.21 no.6
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• pp.537-543
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• 2017

Underwater glider is the long-term operating underwater robot that was developed with a purpose of continuous oceanographic observations and explorations. Torpedo-type underwater glider is not efficient from an aspect of maneuverability, because it uses a single buoyancy engine and motion controller for obtaining propulsive forces and moments. This paper introduces a ray-type underwater glider(RUG) with dual buoyancy engine, which improves the control performance of buoyancy and motion compared with torpedo-type underwater glider. Carrying out Computational Fluid Dynamics (CFD) analysis as static pitch drift test, the performance of fluid resistance for gliding motion was identified. Based on the calculated hydrodynamic coefficients, the dynamic simulation compared and analyzed the motion performance of torpedo-type and ray-type while controlling same volume of buoyancy engine. Small-sized model of RUG was developed to perform fundamental performance tests.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.12
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• pp.138-145
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• 2016

This study was conducted to examine the effects of a career coaching program on nursing students' career decision making self efficacy, self-leadership, and employment-stress. The study was designed using a nonequivalent control group pretest-posttest design, and data were collected between June 15 and July 31, 2016. The participants consisted of 62 4-year nursing students in D College of B City who were assigned to an experimental group (n=32) or a control group (n=34). The career coaching program consisted of 10 sessions of combined individual coaching, small group coaching and group coaching. The data were analyzed using descriptive analysis, a t-test, ${\chi}^2$ test, and paired t-test with the SPSS/WIN 21.0 program. After receiving the career coaching program, a difference was observed in career decision making self efficacy (t=4.99, p<0.001), self-leadership (t=5.08, p<0.001), and employment-stress (t=5.08, p<0.001) of the experimental group. The results of this study indicate that the career coaching program was effective at increasing career decision making self efficacy and self-leadership, as well as decreasing employment-stress in nursing students.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.5
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• pp.133-140
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• 2017

This study was conducted to determine the casual relationship among family support, social support, workplace spirituality, and quality of life (QOL) for middle-aged, male office workers, as well as the effects of family support, and social support on their QOL with the mediation of workplace spirituality. The participants were 288 middle-aged, male office workers, and the data were collected from 14 October to 30 November, 2016, through questionnaires. The data were analyzed with descriptive statistics and Pearson's correlations using PASW 21.0, while the AMOS 18.0 program was used for structural equation modeling (SEM), and the fitness of the final model was determined using RMSEA .05, GFI .98, AGFI .94 and NFI .96. The results of this study can be summarized as follows. There were correlations between family support, social support, workplace spirituality, and QOL for the middle-aged, male office workers. Second, family support (${\beta}=.60$, p<.001) and social support (${\beta}=.47$, p<.001) had a direct effect on their workplace spirituality. Third, family support had direct (${\beta}=.12$, p=.002) and indirect (${\beta}=.10$, p<.001), while social support also had direct (${\beta}=.12$, p<.001) and indirect (${\beta}=.08$, p<.001) effects on their QOL. The findings also suggested that workplace spirituality had a partial mediating effect between the family support, social support, and QOL of the middle-aged, male office workers.