Objectives: Tourette syndrome (TS) is a disease that occurs evenly in many social classes. Despite the long experience of drug treatment, the preference is low due to various side effects. The aim of this study was to discover herbal medicine resources through network pharmacology analysis predicted to be useful for Tourette syndrome. Methods: We used Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP) to identify herbal medicines that can be used for TS by using network pharmacology research methods and to predict the mechanism of action. After evaluating compounds of each identified herb, molecular target proteins and mechanisms of action were analyzed, focusing on compounds that are likely to exhibit clinical activity in consideration of the pharmacokinetic parameters of these individual compounds. Results: Fifty nine ingredients such as atropine, veraguensin, and nuciferin among the compounds contained in 48 types of medicinal herbs such as Daturae Flos (洋金花), Salviae Radix (丹参), and Nelumbinis Plumula (蓮子心) act on the D(2) dopamine receptor, which is a protein involved in the development of TS. It has been found that atropine, veraguensin, and nuciferin are highly likely to exhibit activity by acting on the G protein-coupled receptor signaling pathway. Conclusions: It can be used in conjunction with non-invasive treatment means such as FCST Yinyang Balancing Appliance with herbal therapy to bring about a significant therapeutic effect, and it will be possible to develop a treatment that can replace drug therapy used in Western medicine.
Objective : Describe the phenomenon of "clear qi below, turbid qi above" as found in the Somun Eumyangeungsangdaelon (Major Essay on Yinyang Resonances and Appearances 素問 陰陽應象大論) and compare this pattern with water-grain dysentery and flatulence symptom patterns in the Sanghallon (Treatise on Cold Damage). Method : Study the annotation of the Hwangjenaegyeong (Yellow Emperor's Internal Classic 黃帝內經) and compare the results with the Sanghallon's water-grain dysentery and flatulence. Conclusions and Results : The causes of water-grain dysentery and flatulence are associated with the ascending and descending properties of Yin and Yang. Additionally, these symptoms can also be caused by pathogenic heat, turbid pathogenic factors, and interruption of the movement of clear and turbid qi. Aspects of water-grain dysentery resemble several patterns found in the Sanghallon. If caused by a weakness of yang qi, it resembles Sayeoktang (四逆湯) syndrome. Weakness of spleen qi resembles Ijungtang (理中湯) syndrome. Flatulence is similar to fullness in the chest syndrome, which in the Sanghallon is caused by an obstruction of cold qi. If there is excessive cold, water-grain dysentery is similar to the syndrome of Gyeolhyung (結胸). If the qi is not scattered, deficiency syndrome is similar to Gyejigejagyaktang (桂枝去芍藥湯) syndrome and excess syndrome is similar to Mahwangtang (麻黃湯) syndrome. When flatulence is caused by fever in chest, it is similar to Chijasitang (梔子?湯) syndrome. When caused by heat and phlegm build up in chest, it is similar to Sipjotang (十棗湯) syndrome.
The Wenzi is the material criticized about the relation bamboo-slip literature and current literatures in the academic world. If is true or not, because we don't know the author and the records accurately. In this study, to sublate the researching method of HuangLao philosophy that vogues the boundary between Zajia, on the basis of volumes with bamboo-slip literature and the present literatures shared, I discuss the peculiarity of Wenzi HuangLao philosophy, comparing Dao-theory of Daoist. The Wenzi is HuangLao philosophy of Rujia pattern that doesn't understand as the Dao-Fa school. And its origin is Laozi philosophy. It accepts Zujia philosophy, putting first in importance about Rujia philosophy. In this study, the origin of the Wenzi is Laozi philosophy theoretically, but I discuss that the Wenzi is the early literature forming Rujia pattern HuangLao philosophy. And the Wenzi tries to combine the theory of Rujia in the social political category.
Eun Ju Lee;Tae Kyung Kim;Chang Min Shin;Cheol Hong Kim
Journal of TMJ Balancing Medicine
/
v.12
no.1
/
pp.22-27
/
2022
Objectives: The purpose of this study is to report the effect of Korean medical treatment with TBT (Temporomandibular Joint Balancing Therapy) on Anxiety disorder patient with dyspnea. Methods: In this study, an Anxiety disorder patient with dyspnea was admitted to △△ Korean medicine Hospital from Nov 1st, 2022 to Nov 23rd, 2022. During the admission period, the patient was treated by Korean medical treatment(acupuncture, pharmacopuncture, herb medicine, etc.), especially using TBT and Western medical treatment (Pharmacotherapy). Beck Anxiety Inventory (BAI) and VAS were used for measuring the Anxiety and Dyspnea. Results: After treatment for 30days, the BAI showed a decrease from 33 to 19, The VAS associated with dyspnea also decreased from 6 to 1 and VAS associated with Neck Pain decreased from 5 to 3. Conclusions: These results showed that Korean medical treatment especially using TBT may have an effect on reducing symptoms of dyspnea due to Panic Attack. But the further researches are needed.
The Korean traditional color passed down over countless generations has surpassed both surpassed both time and space and continue today to breathe life into its people's everyday. In order to clarify the characteristics of Korean traditional color blue and red, we investigate the names of them and measured the color tones of textile remains in Chosun era. The characteristics of Korean traditional color blue and red have been surveyed by means of the examination of color names in many famous literatures in Chosun era. Korean terms for color tones were characterized by enormous variety of epithes crowned on them. The color names mentioned contain many unaccountable epithes which were characterized also deep colors and light colors were dominant in it. As a means of enhancing possibilities within limited colors, the commoners increased the names for varying tones of blue color group(32kinds) and red color group(40kinds). These "blue(indigo dyeing)' and 'red(safflower dyeing)' in Chosun era were shown very high frequency in use and the costume colors in Royal Court. With combination of these various blue and red colors they represented a thought of color based on Yinyang Theory and created a polished aesthetic taste. The color samples of textile remains in museum were measured and designated by Munsell color system and the ISCC-NBS color designation system. THe appeared rates were derived on Chosun era and features of colors using on the period were discussed. We aim to present specific recipes in indigo dyeing and safflower dyeing for using our apparel product and folk art.
This article introduce the status and research overview of Korean Confucianism in Eastern Asia with the macroscopic view. Mainly making Tuixi as an example on this basis, respectively make introduction and analysis of research overview among the modern Chinese mainland, Taiwan and Japan towards Korean Confucianism. The scholars who are from Chinese mainland think highly of the expression on meaning and principle in the research of Korean philosophy, which is shown the fair and peace; The scholars who come from Taiwan are obviously impacted by the western world(Taiwan uses the means influenced by the western thinking method) in the means of researching the Korean Confucianism; Japanese persistently rely on the literature and try to reproduce the objectivity of historicism. For decades, the research of Tuixi had made great achievements in Eastern Asia. It had understood the allover content of its thought, It is also worth thinking about the correlation between Tuixi psychology and Yinyang study in Japan, Japan and Taiwan in recent years. Any research is unavoidable to start from own countries, areas and ideological consciousness, but there is a question idea behind the back that comes from emotion and fact. Making the advantage in study meanings and communication in question consciousness will be beneficial to the continuous development of the study of Tuixi in depth and expand its influence.
This article introduce the status and research overview of Korean Confucianism in Eastern Asia with the macroscopic view. Mainly making Tuixi as an example on this basis, respectively make introduction and analysis of research overview among the modern Chinese mainland, Taiwan and Japan towards Korean Confucianism. The scholars who are from Chinese mainland think highly of the expression on meaning and principle in the research of Korean philosophy, which is shown the fair and peace; The scholars who come from Taiwan are obviously impacted by the western world(Taiwan uses the means influenced by the western thinking method) in the means of researching the Korean Confucianism; Japanese persistently rely on the literature and try to reproduce the objectivity of historicism. For decades, the research of Tuixi had made great achievements in Eastern Asia. It had understood the allover content of its thought, It is also worth thinking about the correlation between Tuixi psychology and Yinyang study in Japan, Japan and Taiwan in recent years. Any research is unavoidable to start from own countries, areas and ideological consciousness, but there is a question idea behind the back that comes from emotion and fact. Making the advantage in study meanings and communication in question consciousness will be beneficial to the continuous development of the study of Tuixi in depth and expand its influence.
This paper discusses the geometrical interpretation of the Taegeuk Shapes of Kameun Temple through the geometric analysis of mathematics. Based on the literature, This paper attempted to clarify that the origin of Gameunsa's founding of the spirit of patriotism may coincide with historical records through historical literature and geometric meaning. First, the background of the founding of Kameun temple, geographical location located near the East Sea, especially the history of the ancient Chinese mathematics at the time, And that mathematical knowledge influenced all fields such as agriculture, architecture, and art. Secondly, it is related to the historical record as the space of about 60 centimeters, which is uniquely underground, was identified as the structure of the excavated space. It is thought that there is a strong correlation with the origin that the King Munmu changed into a dragon, and set up the temple to be able to stay. Based on these, the clues of the interpretation of the taegeuk and the triangular pattern were searched in the samcheon yanggi(參天兩地) of the Oriental and circumference of the Western. The taegeuk and triangular patterns represent the symbols of yin-yang harmony, which correspond to the origin of its creation. the Korean people regarded the mysterious dragon as a symbol of yinyang harmony. In conclusion the Shapes of Kameun temple's stone is consistent with the contents mentioned in the historical record.
This thesis examined interpreting methodology of Do Won Lew Seung Kug(1923~2011) is based on the principle of Juhng-yaug. His lifelong academic aim was searching for the theory that enables global community to co-exist peacefully through humanitarianism that leads to reconciliation and mutual benefits. The research of the history of Korean thoughts provided him with the clue for his theory. According to Do Won, Korean thoughts pursue the Juhng-yaug's value of 'Yin and Yang accordance' rather than the I-Ching's value of 'suppress Yin and elevate Yang'. He furthermore asserts the concept of the middle (中), which harmonizes the two extremes by human beings as main agents, has been consistently observed from the action of divination during the ancient period through Juhng-yaug in the late 19th century. Do Won identifies 'human maturity that integrates the extremely conflicting insistences and values and seeks to be reconciled' as the basic character of Korean thoughts. He explains 'Hongikingan[弘益人間, becoming beneficial to the human world] is the idea that embraces the conflicting values symbolized by heaven and the earth. He also illuminates that Choe Chi Won(崔致遠)'s created Poongliu Do by integrating heterogeneity among Confucianism, Buddhim, and Daoism and it was attainable through the various works of mature human beings. Both Toe Gye' s philosophy of Ingeuk(人極, the Great Ultimate of Person) and the concept of Innaecheon(人乃天, Human Being right is Heaven) of Donghak are excellent examples of Humanitarianism that sublate two extremes. In Korea, the prototype of this thought has penetrated its entire history in the various circumstances of the period. The grand finale is Juhng-yaug of which the pursued values are 'Yin and Yang accordance' and mature humanitarianism revealed by the thoughts of the Person of the Central Ultimate (皇極人,至人) and Central Ultimate (皇極). Therefore, Humanitarianism in Korean thoughts clearly makes its appearance by the time of Juhng-yaug and it functions as a keyword to illuminate the entire history of Korean thoughts in reverse.
Zhōuyì周易 is intended to explain the affairs of human beings by observing the images and works of all things in the universe, abstracting them into the $b{\bar{a}}gu{\grave{a}}$八卦, calculating the process and inducing the outcome by the method of stalk divination, in which this paper finds the origin of natural scientific thought of Zhōuyì. The way of Zhōuyì's thought on the natural science is distinguished from that of the Western's. In the West, people dismantled the objects into the parts until they reached the atom and analyzed them by the principle of causality to draw an axiomatic truth. In the meantime Zhōuyì observed and studied the dynamic functions and changes of all things for the convergence of the whole. While the way of Zhōuyì's thinking could have not contributed to the development of modern scientific development, that of the West overwhelmed Asian development passing through the period of enlightenment during 16-17 century. This paper tries to articulate the points where Zhōuyì can share its theory with the contemporary science by finding the traces of scientific thoughts in Zhōuyì. It encounters its ground from the methodology of natural science and scientific statements proposed by Zhōuyì. The essential concepts of Zhōuyì are induced from all things in nature. This can be considered as the idea of '法自然'(emulating the patterns and examples from nature). Also they observed the images and changes seen by the habits of animals, plants and human beings to sense and perceive their laws. These are regarded as the methodology of natural science in Zhōuyì. As a book of divination, the way of stalk divination is designed to calculate the future by using the system of 'numbers'. 'tàijí太極', ' yīnyáng陰陽', 'four symbols四象', '$b{\bar{a}}gu{\grave{a}}$八卦' and 'wǔxíng五行' are the essential concepts of Zhōuyì to represents the dynamic phenomena and changes of the natural order. Among them '$b{\bar{a}}gu{\grave{a}}$八卦' is a presentment to explain the structure of the world not by the individual analysis of things but by the unification of the whole through the contradictions and interchanges among them to reach the new orders. As of now, the studies of Zhōuyì in Korea have focused on the traditional perspectives, such as political and ethical philosophy. Some of recent studies, having interpreted Zhōuyì with scientific inclination have generated controversy 'Can Zhōuyì be a science?', for which scholars have hard time to reach the agreement. This paper tries to find the headwaters of the contemporary natural science by elaborating the methodology of natural science stated in Zhōuyì.
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