• Toxicological Research
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• v.23 no.1
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• pp.19-24
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• 2007

We demonstrate that paclitaxel, an antitumor agent derived from yew tree, inhibits LPS- and $IFN-{\gamma}$-induced NF-kB/Rel activation in RAW 264.7 cells. Previously, paclitaxel ($>10{\mu}M$) has been known to induce iNOS gene expression in macrophages. However, in the previous report we described that the pretreatment of macrophages with low concentration of paclitaxel ($0.1{\mu}M$) for 8 h inhibited LPS-induced iNOS gene expression. Pretreatment of RAW 264.7 cells with paclitaxel significantly inhibited NF-kB/Rel transcriptional activation. Electrophoretic mobility shift assay further confirmed that pretreatment of macrophages with paclitaxel inhibited NF-kB/Rel DNA binding. Taxotere, a semisynthetic analog of paclitaxel, also inhibited LPS- and $IFN-{\gamma}$-induced iNOS gene expression. Collectively, these series of experiments indicate that paclitaxel inhibits iNOS gene expression by blocking NF-kB/Rel activation.

• Structural Engineering and Mechanics
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• v.5 no.5
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• pp.645-662
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• 1997

A nonlinear semi-three-dimensional layered finite element procedure is developed for cracking and failure analysis of reinforced concrete beams and the spandrel beam-column-slab connections of flat plates. The layered element approach takes the elasto-plastic failure behaviour and geometric nonlinearity into consideration. A strain-hardening plasticity concrete model and a smeared steel model are incorporated into the layered element formulation. Further, shear failure, transverse reinforcement, spandrel beams and columns are successfully modelled. The proposed method incorporating the nonlinear constitutive models for concrete and steel is implemented in a finite element program. Test specimens including a series of reinforced concrete beams and beam-column-slab connections of flat plates are analysed. Results confirm the effectiveness and accuracy of the layered procedure in predicting both flexural and shear cracking up to failure.

• Journal of Forest and Environmental Science
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• v.31 no.2
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• pp.109-118
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• 2015

Allelopathy is an ecological phenomenon that refers to the beneficial or harmful effects of one plant on another plant, both crop and weed species, by the release of organic chemicals (allelochemicals) from plant parts by leaching, root exudation, volatilization, residue decomposition in soil and other processes in both natural and agricultural systems. Allelopathy can affect many aspects of plant ecology including occurrence, growth, plant succession, the structure of plant communities, survival, dominance, diversity, and plant productivity. In this review, we describe the concept of allelopathy, some mechanisms of operation within plants and then focus on a select number of gymnospermous tree genera: Ephedra, Pinus, Taxus, Cedrus, Juniperus, Picea, Cunninghamia and Araucaria. Pinus, Taxus (yew) and Cedrus (cedar) trees have a strong negative allelopathic effect on the germination, growth, or development of other plant species in the forest community.

• Proceedings of the Korean Society of Toxicology Conference
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• 2002.05a
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• pp.117-117
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• 2002

Paclitaxel isolated from the pacific yew tree, Taxus brevifolia, is microtuble-stabilizing agent that has a promising anticancer activity against a wide variety of tumors such as ovarian, breast and lung cancers. Because of its poor water solubility, paclitaxel is currently formulated in a mixture of polyoxyethyleneglycerol triricinoleate 35 (Cremophor EL) and dehydrated ethanol USP (1:1 v/v).(omitted)

• Proceedings of the KIEE Conference
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• 1995.11a
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• pp.496-498
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• 1995

A power line data transmission method has been developed and presented in this paper. Although there have been efforts to develope power line data transmission techniques, none of them has been accepted as a standard. Thus, our method follows a defacto standard CENELEC's recommendations. The paper presents the algorithm as well as experimental results.

• Research in Mathematical Education
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• v.15 no.2
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• pp.159-179
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• 2011

This paper reports on the learning journeys in mathematical problem solving of 21 teachers enrolled on a Masters of Education course entitled Discrete Mathematics and Problem Solving. It draws from the reports written by these teachers on their personal journeys: the commonalities and differences among them in terms of how they look at their own problem solving experiences, what language they employ in talking about problem solving, and what impact the course has on their views about problem solving. One particular aspect of problem solving instruction, a pedagogical innovation called the Practical Worksheet, is addressed in some detail. These graduate students are full-time mathematics teachers with at least two years of classroom experience. They include primary and secondary teachers.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2006.09b
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• pp.1057-1058
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• 2006

The preparation of $Ti_{50}Cu_{28}Ni_{15}Sn_7$ metallic glass composite powders was accomplished by the mechanical alloying of a pure Ti, Cu, Ni, Sn and carbon nanotube (CNT) powder mixture after 8 h milling. In the ball-milled composites, the initial CNT particles were dissolved in the Ti-based alloy glassy matrix. The bulk metallic glass composite was successfully prepared by vacuum hot pressing the as-milled CNT/$Ti_{50}Cu_{28}Ni_{15}Sn_7$ metallic glass composite powders. A significant hardness increase with the CNT additions was observed for the consolidated composite compacts.

• The Research Journal of the Costume Culture
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• v.12 no.1
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• pp.182-198
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• 2004

The purpose of this study was to analyze the previous make-up studies. A number of publications and journals were reviewed and analyzed carefully. The results of review and analysis were as follows: There were many different subjects in make-up studies and They can be divided into ten types : cosmetics purchase behavior, change of make-up culture and comparison, make-up trend by era, cosmetics industry's standing of today and strategy, art trend in make-up, brand preference of cosmetics, make up attitude, recognition about imported cosmetics and purchase behavior, color preference of cosmetics, the relationship between self-concept and make-up. In general, the cosmetic purchase behavior studies are conducted most actively. According to result that analyze existent study, special duality of cosmetics purchase action appears very variously according to standard of classification of study target and study target. But, study target and method of study are not various, and purchase behavior study collected with make-un and clothes is yew lacking. Therefore, in this study, wished to discover problem of virtue study because analyzes studies about previous make-up and present forward study direction.

• Korean Journal of Bronchoesophagology
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• v.3 no.2
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• pp.261-269
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• 1997

When performing an endotracheal intubation or tracheotomy to an unconscious patient in emergent situations, one should consider the possibility of later complication of laryngo-tracheal stenosis which can result in difficulties in decannulation. Laryngo-tracheal stenosis is a bothersome problem developing as a complication of treatment by tracheotomy with a cuffed tube and long-term endotracheal intubation with assisted ventilation. One hundred twenty-three cases of laryngo-tracheal stenosis patients during the four yew period from May 1992 to April 1996 were restrospectively reviewed according to several parameters such as the duration of intubation, site of stenosis, treatment modality and, site of tracheostoma. The present report is an analysis of these materials to search for the possible etiologic factors and its proper preventive methods. It was desirable that the endotracheal intubation should be limited within 20 days at most. Tracheotomy performed by non-otolaryngologists has a tendency to be on a higher level of trachea. Technical precautions should be taken into consideration when doing a tracheotomy. The success rate of decannulation of tracheal T-tube was 78.8% and it required average 11 months.

• Journal of the Korean housing association
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• v.14 no.4
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• pp.11-19
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• 2003

This study intends to predict prospective defects and establish the plan of Preventive Maintenance through research and analysis of defect occurrences and their repair costs in the public equipment of ‘H’ apartment house from 1998 to 2001. According to results of the analysis, more than 90% of defects and their repair costs for 4 years of the building have occurred in heating, hot water and water supply equipments. In case of specific classification in each equipment, more than 60% of defects were found at hot water pipes and heating pipes, and their repair costs covered more than 60% of the total defect costs. After two repairs by ‘Preventive Maintenance’ had been performed in the year 1998, total defects and defects of each equipment each yew have increased in number from 1999 to 2001. But total repair costs and repair costs of each equipment have not increased as time has gone by, because repair costs have relationship with the price of materials and labor, the part of defect and the scale of repair.