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EXPERIMENTAL STUDY ON THE DISSOLUTION COMPONENTS AND CORROSION PRODUCTS OF SEVERAL AMALGAMS IN ARTIFICIAL SALIVA (인공타액에서 수종 아말감의 부식시 용해성분 및 표면 부식 생성물에 관한 실험적 연구)

  • Cho, Seung-Joo;Lee, Myung-Jong
    • Restorative Dentistry and Endodontics
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    • v.19 no.1
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    • pp.1-26
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    • 1994
  • The purpose of this study was to investigate the dissolution components during corrosion of amalgams and to identify surface corrosion products in the modified Fusayama artificial saliva. Four type of amalgam alloys were used: low copper lathe cut amalgam alloy (Cavex 68), low copper spherical amalgam alloy (Caulk Spherical Alloy), high copper admixed amalgam alloy (Dispersalloy) and high copper single composition amalgam alloy (Tytin). Each amalgam alloy and Hg were triturated according to the manufacturer's direction by means of mechanical amalgamator (Capmaster, S.S.White), and then the triturated mass was inserted into the cylindrical metal mold which was 10mm in diameter and 2.0mm in height and condensed with compression of 150kg/$cm^2$ using oil pressor. The specimens were removed from the mold and stored at room temperature for 7 days and cleansed with distiled water for 30 minutes in an ultrasonic cleaner. The specimens were immersed in the modified Fusayama artificial saliva for the periods of 1 month, 3 months and 6 months. The amounts of Hg, Cu, Sn and Zn dissolved from each amalgam specimen immersed in the artificial saliva for the periods of 1 month, 3 months and 6 months were measured using Inductivity Coupled Plasma Atomic Emission Spectrometry (ICPQ-1000, Shimadzu, Japan) and amount of Ag dissolved from amalgam specimen was measured using Atomic Absorption Spectrophotometry (Atomic Absorption/Flame emission spectrophotometer M-670, Shimadzu, Japan). A surface corrosion products of specimens were analysed using Electron Spectroscopy Chemical Analyser (ESCA PHI-558, PERKIN ELMER, U.S.A.). The secondary image and back scattered image of corroded surface of specimens was observed under the SEM, and the corroded surface of specimens was analysed with the EDX. The following results were obtained. 1. The dissolution amount of Cu was the most in high copper admixed amalgam(Dispersalloy) and the least in high copper single composition amalgam(Tytin). 2. Sn and Zn were dissolved during all the experiment periods, and dissolution amounts were decreased as the time elapsed. 3. Initial surface corrosion products were ZnO and SnO. 4. Corrosion of ${\gamma}$ and ${\gamma}_2$ phase in low copper amalgams was observed and Ag-Cu eutectic alloy phase was corroded in low copper spherical amalgam(Caulk Sperical Alloy). 5. Corrosion of ${\gamma}$ and $\eta$' phase in high copper amalgams was observed and Ag-Cu eutectic alloy phase was corroded in high copper admixed amalgam(Dispersalloy). 6. Sn-Cl was produced in the subsurface of low copper amalgams and high copper admixed amalgam.

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One dimensional inhomogeneous aperture modulation effects on the MTF of optical system II (일차원적 비균일 개구변조시 광학계의 최적상면 MTF에 미치는 영향)

  • 홍경희
    • Korean Journal of Optics and Photonics
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    • v.9 no.5
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    • pp.277-281
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    • 1998
  • One dimensional inhomogeneous aperture modulation effects on the MTF of optical system was investigated. The lens under test was a doublet made in Korea. It has 10 mm effective diameter, 87.8 mm effective focal length. The ray-fans and spot diagrams were calculated and presented on the picture for on-axis and off-axis (field of view, $1^{\circ}$ and $2^{\circ}$). Aperture modulation was carried out by positioning a aperture modulator close contacter with the lens under test. We bought two modulators from Edmud Company in U.S.A. One was linear type and the other was stepped type. The MTFs were measured on the best of focus for each modulated aperture where the MTF has the highest value for 60 line/mm and were compared with one another. For on-axis, the MTFs of some modulated apertures had higher values than the MTF of unmodulated aperture in the high frequency region. In the case of off-axis, at the field of view $1^{\circ}$, the MTF values of some modulated aperture are improved prominently and some other one are disimproved. At the field of view $2^{\circ}$ most of the MTFs of modulated apertures had lower values than the MTF of unmodulated aperture except the MTFs of linear and inverse linear type aperture in the high frequency area. But the values of MTFs in high frequency region were too low for actual use.

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An Analysis of Effectiveness for Permissive Warrants on the Restrictive Left-Turn Signal Control in Urban Arterial Roads (도시 간선도로에서 제한적 좌회전 신호운영의 적용기준 및 효과분석에 관한 연구)

  • Jeong, In-Taek;Lee, Yeong-In
    • Journal of Korean Society of Transportation
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    • v.27 no.5
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    • pp.17-28
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    • 2009
  • There are many limitations in dealing with rapidly changing traffic demand in urban cities. Thus recently, traffic operation and management skills are more emphasized rather than the expansion of traffic facilities. In particular, in the interrupted flow formed by signalized intersections, it is quite important to give optimal signal timing to each intersection with consideration of progression. However, as fixed signal times per direction can affect passing capacity in signalized intersections, the present four-signal phase including a left-turn signal has many limitations, including reduction of directional road capacity when traffic demand is increases dramatically during peak hours. Because of this problem, lots of studies about internal metering techniques for oversaturated signal control skills have progressed but these techniques are not used widely due to the absence of detectors for queue sensing in real-time signal control systems. In this research, a new methodology called the "restrictive left-turn signal control", which is already used at the intersection above Samsung subway station, is suggested in order to reduce control delay of urban arterial roads. The restrictive left-turn signal control allows a driver to make a U-turn and then a right turn instead of turning left in that intersection. With this change, the restrictive left-turn signal control can contribute to increased intersection capacity by reducing the number of signal phases and maximizing the through phase time. However, road structure and traffic conditions at the target intersections should be considered before the adoption of the proposed signal control.

Impacts of Delivery Vehicle Routing on Different Inventory Strategies and Network Configurations (재고전략 및 네트워크 구성에 따른 배송차량의 운영특성 연구)

  • Won, Min-Su;Gang, Gyeong-U
    • Journal of Korean Society of Transportation
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    • v.28 no.5
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    • pp.91-106
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    • 2010
  • Recently, interest in supply chain management is rising along with the increasing oil prices and traffic congestion. In particular, people started studying the issue, but realized that advantageous strategies for suppliers and retailers are not always advantageous to a carrier. Therefore, in this study the atuhors set up a simulation scenario to understand delivery vehicle routing problems under various inventory policies, namely Economic Order Quantity (EOQ) and Periodic Order Quantity (POQ) and network configurations. First, the authors made a virtual supply chain. Then they analyzed characteristics of delivery vehicle routing under various inventory policies (EOQ and POQ) and network configurations. As a result, the POQ inventory policy decreases the number of vehicles, the number of drivers, and the service time of vehicles. Also, the centralized network increases the load factor of vehicles and decreases the service time of vehicles. In other words, the centralized network and the POQ inventory policy are better for the carrier. These results show a savings of 15,556,806 won ($13,389.10) in a month: a reduction of 17%.

Influence of Kamijihwang-hwan on the Hypoxic Damage of Cultured Cerebral Neurons from mouse and SK-N-MC cells (가미지황환이 저산소성 신경세포 손상에 미치는 영향)

  • Kyung Baek Yeun;Ju Sung Min;Kim Kun Jun;Kim Dae Keun;Kang Jeong Ho;Lee Young Chan;Lee Jun;Kim Young Mok;Jeon Byung Hun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.4
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    • pp.1082-1091
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    • 2003
  • To elucidate the neuroprotective effect of Kamijihwang-hwan(KSH) on nerve cells damaged by hypoxia, the cytotoxic effects of exposure to hypoxia were determined by XTT, NR, MTT and SRB asssay. The activity of catalase and SOD was measured by spectrophometry, and TNF-α and PKC activity was measured after exposure to hypoxia and treatment of Kamijihwang-hwan(KSH) water extract(KJHWE). Also the neuroprotective effect of KJHWE was researched for the elucidation of neuroprotective mechanism. The results were as follows ; Hypoxia decreased cell viability measured by XTT, NR assay when cultured cerebral neurons were exposed to 95% N2/5% CO₂ for 2~26 minutes in these cultures and KJHWE inhibited the decrease of cell viability. H₂O₂ treatment decreased cell viability measured by MTT, and SRB assay when cultured cerebral neurons were exposed to 1-80 uM for 6 hours, but KJHWE inhibited the decrease of cell viability. Hypoxia decreased catalase and SOD activity, and also TNF-α and PKC activity in these cultured cerebral neurons, but KJHWE inhibited the decrease of the catalase and SOD activity in these cultures. Hypoxia triggered the apoptosis via caspase activation and internucleosomal DNA fragmentation. Also hypoxia stimulate the release of cytochrome c form mitochondria. KJHWE inhibited the apoptosis via caspase activation induced by hypoxia. From these results, it can be suggested that brain ischemia model induced hypoxia showed neurotoxity on cultured mouse cerebral neurons, and the KJHWE has the neuroprotective effect in blocking the neurotoxity induced by hypoxia in cultured mouse cerebral neurons.

Comparative Study on the Inhibition Effect on Apoptosis in Neuro2A Cell on the Region of Zizania Latifolia(Radix, Rhizoma, Herba) (고장초의 부위별(뿌리, 줄기, 전초) Neuro2A 신경세포고사에 대한 억제 효과 비교 연구)

  • Cha, Yun-Yeop
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.20 no.4
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    • pp.936-941
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    • 2006
  • To prevent human body injury from oxidative stress, antioxidants are very important and many research about antioxidants are generally being conducted. Hydrogen peroxide$(H_20_2)$ that is one of vitality oxygen species has been seen that cause various diseases, DNA damage and gene change. We have already known that the inhibition effect of Zizania latifolia Radix, Rhizoma on apoptosis induced by $H_2O_2$ in Neuro2A cell. And the purpose of this study was that we made a comparative study on the inhibition effect of apoptosis in Neuro2A cell on the region of Zizania latifolia(Radix, Rhizoma, Herba). Neuro2A cells were cultivated in RPMI(GibcoBRL) with 5% FBS and treated with $H_2O_2$ and Zizania latifolia(Radix, Rhizoma, Herba). Separately we measured the cell viability and analyzed DNA fragmentation. Activity of PARP, Cytochrome C, caspase-9, caspase-3, p53, p21, Bax and Bcl-2 in the cell was examined by using western blot. The results obtained were as Follows: The cell viability in all of Zizania latifolia (Radix, Rhizoma, Herba) treatment (60ug/m1<) decreased significantly compared with that of none treatment(p<0.001). Zizania latifolia Radix increased cell viability was most effective of three regions. But we had no significant difference among three regions. All of Zizania latifolia (Radix, Rhizoma, Herba) increased cell viability about twice as much as that being injury by $H_2O_2$,(Zizania Latifolia (Radix, nhizoma, Herba) 20ug/m1, $H_2O_2$ 200uM, p<0.001). DNA fragmentation developed by $H_2O_2$, but was not developed in all of Zizania latifolia (Radix, Rhizoma, Herba) treatment. PARP, Cytochrome C, caspase-9 and caspase-3 activated all by $H_2O_2$ but were not activated in all of Zizania latifolia (Radix, Rhizoma, Herba) treatment. P53, P2l and Bax activated by $H_2O_2$, and Bcl-2 got into inactivation. But the opposite results appeared in all of Zizania latifolia (Radix, Rhizoma, Herba) treatment. In conclusion, these results suggest that all of Zizania latifolia (Radix, Rhizoma, Herba) inhibit the development of DNA fragmentation and apoptosis by $H_2O_2$and the antioridant action of all of Zizania latifolia (Radix, Rhizoma, Herba) is effective.

Analgesic Effects of Sokyungwhalhyul-tang on Constriction Nerve Injury-Induced Neuropathic Pain in Rats (말초 신경병증성 통증 모델에서 소경활혈탕의 진통 효과)

  • Kim, Kyung-Yoon;Jeong, Hyun-Woo;Choi, Chan-Hun;Kim, Hyung-Woo;Kim, Gi-Do;Sim, Ki-Cheol;Kim, Gye-Yeop
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.25 no.2
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    • pp.195-201
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    • 2011
  • Nardostachys chinensis;Anti-proliferation;Cell cycle arrest;Differentiation;U937 cells; This study was conducted to determine the analgesic effect of Sokyungwhalhyul-tang(SKWHT) using the model of peripheral neuropathic pain model. A model of neuropathic pain was made by ligating left 5th lumbar spinal nerve of rats. After 1 days, the extract of SKWHT was orally administered daily. Rats were divided into four groups; (1) Control group(n=6), (2) Experimental group I(SKWHT-OA1, 100 mg/kg, n=6), (3) Experimental group II(SKWHT-OA2, 300 mg/kg, n=6), (4) Experimental group III(SKWHT-OA3, 500 mg/kg, n=6). After that, we examined the withdrawl response of neuropathic rats legs by von Frey filament and Hot plate at pre, $1^{th}$, $4^{th}$, $7^{th}$, $14^{th}$, $21^{th}$ days after the induction of neuropathic pain. And also we examined c-fos, GOT, GPT and histological study of Liver at 21th days. von Frey filament and Hot plate were increase in experimental group I, II, III than Con. especially group III was most significantly analgesic effect than the other groups at $14^{th}$, $21^{th}$ days. In c-fos protein expression on spinal cord, group III was most significantly reduction immunoreactivity at $21^{th}$ days and in blood serum GOT & GPT levels and histologic finding of Liver in all experimental groups were no significant difference with Con at $21^{th}$ days. According to the above results, SKWHT(500 mg/kg) may have a significant analgesic effect on the neuropathic pain.

디지털홈서비스의 수용에 영향을 미치는 요인에 관한 실증연구

  • Mun, Hyo-Gon;O, Jae-In
    • Proceedings of the Korea Society of Information Technology Applications Conference
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    • 2006.06a
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    • pp.130-137
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    • 2006
  • 본 논문은 디지털홈서비스의 실제 이용자들에 대한 실증분석을 통해 수용에 영향을 미치는 요인들을 밝히기 위한 연구이다. 디지털홈서비스의 특성에 맞게 기술수용모형(TAM)을 확장, 수정된 연구모형을 개발, 가설을 설정하여 분석하였다. 외부변수로 이용자의 특성을 채택하였으며, 디지털홈서비스가 가정 내 기술임을 고려하여 신념변수로 '지각된 이용용이성'과 '시각된 즐거움'외에 '지각된 편의성', '지각된 안전성', '지각된 삶의 질 향상'이라는 변수를 추가하였고 종속변수로는 '이용행동'을 설정하였다. 205명의 실제 이용자를 대상으로 한 설물조사 중 201개의 유효표본을 분석하였고, 신뢰성과 타당성 모두 통계적으로 적합한 것으로 나타났다. AMOS 4를 이용한 구조방정식 모형분석을 통해 24개의 가설검증 결과, 13개의 가설이 채택되었다. 이용자 개인의 특성 중 경험과 교육훈련은 지각된 이용용이성에 정(+)의 영향을 미쳤으며 혁신성은 지각된 즐거움, 지각된 편의성, 지각된 안전성, 지각된 삼의 질 향상에 대하여 정(+)의 영향을 미치고 있었다. 또한 지각된 이용용이성이 다른 신념변수인 지각된 즐거움, 지각된 편의성, 지각된 안전성, 지각된 삶의 질 향상에 정의 영향을 미치고 있었다. 종속변수인 이용행동에는 지각된 즐거움과 지각된 편의성, 지각된 삶의 질 향상이 긍정적인 영향을 미치나, 지각된 이용용이성과 지각된 안전성은 영향을 미치지 않았다. 가정에서 쉽게 이용할 수 있다는 것만으로는 적극적인 이용 행동을 기대할 수 없으며, 즐거움 및 실용적인 효익들의 제공 및 이를 위한 다양한 컨텐츠와 프로그램 개발등이 매우 중요하다는 것을 시사하고 있다.3-25%까지 감소하였다. 하지만 산간지역에서는 발육속도가 빨라지고 수량이 증가하거나 큰 변화가 없는 곳도 많아 온난화조건에서도 지역별 정밀기후 추정과 이에 근거한 최적품종의 선택, 이앙기 및 수확기 등 생육기간의 조절이 온난화 대응기술로서 유효할 것으로 기대된다.결과를 분석한 데이터를 차기 메일 발송에 꾸준히 적용함으로써 성공적인 이메일 마케팅 결과를 얻을 수 있을 것으로 기대된다.여 수평적인 의견도출과 각자 역할의 확대 및 변화를 시도할 수 있는 제작흐름이 되도록 고안된 제작구조이다.성을 환기시켜 객관적이고 비판적인 의식을 환기시키는 브레히트의 '소격화'의 효과가 소비자의 관심을 환기시켜 특정한 목적을 달성하려는 광고에 효율적으로 적용된 예 인 것이다. 재미, 기타 독특한 체험을 통해 소비자에게 유희라는 쾌락적 경험을 제공하고자 한다.고도로 통계적 유의차(p<0.001)가 있었다. 즐기는 음료로는 ${\ulcorner}$콜라${\lrcorner}$가 가장 많았으며(46.8%), 그 다음은 사이다, 주스 등의 순으로 나타났으나, 남 여 대학생간에는 유의성있는 차이는 없었다. 음식의 먹는 시기는 점심과 저녁사이의 ${\ulcorner}$간식${\lrcorner}$이 가장 많았으며(42.2%), 남 여 대학생간에는 유의한 차이는 없었다. 패스트푸드는 많은 사람들이 ${\ulcorner}$${\lrcorner}$이 좋기 때문에 이용하며(62.8%), 남 여 대학생간에는 통계적 유의성(p<0.05)이 인정되었다. 5. ${\u

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Response of Black Porgy , Acanthopagrus Schlegelii to the Colored Lights (색광에 대한 감성돔의 반응)

  • 양용림
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.31 no.3
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    • pp.213-219
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    • 1995
  • The author carried out an experiment to find out the response of Black porgy, Acanthopagrus schlegelii [Bleeker] to the color lights. The experimental tank ($360L{\times}50W{\times}55H$cm) was set up in a dark room. Six longitudinal sections with 60cm intervals are marked in the tank to observe the location of the fish. Water depth in the tank was kept 50cm level. Light bulbs of 20 W at the both ends of the tank projected the light horizontally into the tank. Two different colored filters were selected from four colors of red, blue, yellow, and white, and they were placed in front of the light bulbs to make different colors of light. Light intensity was controlled by use of auxiliary filters intercepted between the bulb and the filter. The fishes were acclimatized in the dark for 50 minutes before they were employed in the experiment. Upon turning on the light, the number of fish in each section was counted 40 times in 30 second intervals, and the mean of the number of fish in each section was given as the gathering rate of the fish. The colors favourited by the fish was found in order of blue, yellow, white and red in the day-time and blue, red, yellow and white at night. The difference of the average distribution on two different colors of light was 7.18%(0.35-19.55%), and the difference in the daytime(8.20%) was larger than at night (6.15%). The gathering rate of fish on illumination period didn't show the regular trend of increase and decrease, and was fluctuated with instability. The difference of the gathering rate on two different colors of light wasn't distinct, and the difference in the daytime was larger than at night.

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Monitoring of nervous necrosis virus in fertilized eggs of walleye pollock (Gadus chalcogrammus) (명태(Gadus chalcogrammus) 수정란에서 신경괴사증바이러스(nervous necrosis virus) 모니터링)

  • Nam, U-Hwa;Lee, Jong-Hyuk;Kim, Mi-Ri;Jang, Su-Rim;Yoon, Do-Hyun;Seo, Joo-Young;Kwon, O-Nam;Kim, Jeong-Ho
    • Journal of fish pathology
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    • v.31 no.1
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    • pp.9-13
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    • 2018
  • We previously monitored nervous necrosis virus (NNV) in brain samples of artificially produced walleye Pollock (Gadus chalcogrammus) seedlings, with a low prevalence (1.8%, 1/55) but no clinical symptoms. Given that this virus is considered one of the most serious viral threats for almost all marine aquaculture fish species and characterized by both vertical and horizontal transmission, it would be interesting to monitor NNV in the fertilized eggs as well. We collected fertilized walleye pollock eggs from the farms located in Goseong during January to March, 2017. Approximately 50 mg of eggs were periodically taken from 4 each different batches, and 37 different pooled sample sets in total were made during sampling period. RNA was extracted from the eggs by using Trizol and cDNA was synthesized for RT-PCR for detecting NNV. Primers and PCR conditions are the same as previously described. As a result, NNV was not detected from any of the sample sets by one step PCR (0%, 0/37), suggesting NNV may not be a threat in walleye pollock aquaculture in Korea at present time. However, continuous monitoring for NNV should be conducted because introducing a new species into aquaculture industry involves potentials of disease outbreak and NNV is already known to cause outbreaks in gadoid fishes.