• KSII Transactions on Internet and Information Systems (TIIS)
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• v.16 no.12
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• pp.3991-4007
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• 2022

In the public healthcare, a computational system that can automatically and efficiently detect and classify falls from a video sequence has significant potential. With the advancement of deep learning, which can extract temporal and spatial information, has become more widespread. However, traditional 3D CNNs that usually adopt shallow networks cannot obtain higher recognition accuracy than deeper networks. Additionally, some experiences of neural network show that the problem of gradient explosions occurs with increasing the network layers. As a result, an enhanced three-dimensional ResNet-based method for fall detection (3D-ERes-FD) is proposed to directly extract spatio-temporal features to address these issues. In our method, a 50-layer 3D residual network is used to deepen the network for improving fall recognition accuracy. Furthermore, enhanced residual units with four convolutional layers are developed to efficiently reduce the number of parameters and increase the depth of the network. According to the experimental results, the proposed method outperformed several state-of-the-art methods.

• Wind and Structures
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• v.37 no.1
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• pp.1-13
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• 2023

Due to the irregular shape and the deviation of stiffness center and gravity center, buildings always suffer from complex surface load and vibration response under wind action. This study is dedicated to analyze the surface wind load and wind-induced response of an irregular building, and to discuss the possibility of top swimming pool as a TLD to diminish wind-induced vibration of the structure. Wind tunnel test was carried out on a hotel with irregular shape to analyze the wind load and structural response under 8 wind incident angles. Then a precise numerical model was established and calibrated through experimental results. The top swimming pool was designed according to the principle of frequency modulation, and equations of motion of the control system were derived theoretically. Finally, the wind induced response of the structure controlled by the pool was calculated numerically. The results show that both of wind loads and wind-induced responses of the structure are significantly different with wind incident angle varies, and the across-wind response is nonnegligible. The top swimming pool has acceptable damping effect, and can be designed as TLD to mitigate wind response.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.18 no.4
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• pp.1020-1041
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• 2024

With the development of covert communication technologies, the number of covert communication technologies using blockchain as a carrier is increasing. However, using the transaction amount of digital currency as a carrier for covert communication has problems such as low embedding rate, large consumption of transaction amount, and easy detection. In this paper, firstly, by experimentally analyzing the distribution of bitcoin transaction amounts, we determine the most suitable range of amounts for matrix decomposition. Secondly, we design a novel matrix decomposition method that can successfully decompose a large amount matrix into two small amount matrices and utilize the elements in the small amount matrices for covert communication. Finally, we analyze the feasibility of the novel matrix decomposition method in this scheme in detail from four aspects, and verify it by experimental comparison, which proves that our scheme not only improves the embedding rate and reduces the consumption of transaction amount, but also has a certain degree of resistance to detection.

• International journal of advanced smart convergence
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• v.13 no.2
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• pp.136-141
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• 2024

Chang'an (Chinese: 长安三万里), also known as 30,000 Miles from Chang'an, is a 2023 Chinese 3D animated historical drama film directed by Xie Junwei and Zou Jing.This thesis aims to explore the visual expression of traditional culture in the 3D animated film Chang'an as an example to reveal the reasons for the success of this type of film. The study analyses in detail the design of the character models and costumes, as well as the use of the traditional landscape painting technique of 'white space' in the composition of the screen from the visual aspect. Through the analysis of character design and screen composition, the thesis concludes that the success of Chang'an lies in its elaborate visual design and clever use of traditional culture, which makes it a 3D animation film with both artistic and commercial values. Finally, the thesis concludes that the production of a successful 3D animation film needs to combine the visual elements of 3D animation with traditional culture in order to win audience recognition and achieve commercial success.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.4
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• pp.2277-2282
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• 2013

Purpose: Mammography has been confirmed as the only effective mode to improve the prognosis of patients with breast cancer in Western developed countries, but might not be a good choice in other areas of the world. One of the major challenges in China is to determine an optimal imaging modality for breast cancer screening. This study was designed to clarify the sensitivity of ultrasonography compared with that of mammography in rural China. Methods: We retrospectively studied the sensitivity of mammography and ultrasonography based on 306 breast cancer patients detected by the program of "screening for cervical cancer and breast cancer" performed in Chinese rural areas between January 2009 and December 2011, and analyzed the effects of age, breast density and volume on the sensitivity. Results: Stratified analysis showed that the sensitivity of breast ultrasonography was significantly higher than that of mammography in premenopausal patients (81.4% vs. 61.1%, p=0.02), in women ${\leq}$ 55 years of age (82.2% vs. 63.4%, p<0.01), in the high breast density group (American College of Radiology [ACR] levels 3-4) (85.9% vs. 60.6%, p<0.01) and in the small breast volume group (${\leq}$ 400 ml) (87.1% vs. 66.7%, p<0.01). Age had a significant effect on sensitivity of mammography (breast density and volume-adjusted odds ratio, 6.39; 95% confidence interval, 2.8-14.4 in age group > 55 compared to age group ${\leq}$ 45), but not that of ultrasonography. Neither breast density nor volume had significant effect on sensitivity of mammography or ultrasonography. Conclusions: Ultrasonography is more sensitive than mammography in detecting breast cancer in women under 55 year-old Chinese, especially in those with high-density and relatively small breasts.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.11
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• pp.4733-4738
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• 2014

Purpose: We developed and evaluated a regimen including fotemustine, teniposide and dexamethasone (FTD) for treating patients with central nervous system (CNS) lymphoma based on pharmacokinetic properties of individual agents and in combination. Patients and Methods: In a comparison study, 8 patients with primary CNS lymphoma (PCNSL) and 8 with secondary CNS lymphoma (SCNSL) were treated with FTD (comprising fotemustine 100 mg/m2, 1h infusion, day 1; teniposide 60 mg/m2, >0.5 h infusion, on day 2, 3, 4; dexamethasone 40 mg, 1h infusion, on day 1, 2, 3, 4 and 5; and methotrexate 12 mg, cytosine arabinoside 50 mg plus dexamethasone 5 mg intrathecally, on day 2 and 7). Cycles were repeated every 3 weeks. After response assessment, patients received whole brain radiotherapy. Results: Of the 8 PCNSL patients, 4 (50%) achieved CR and 3 (38%) PR, an overall response rate of 88%. Four patients (50%) were in continuing remission at the end of this study after a median follow-up of 30 months (range 10 to 56 months). Of the 8 SCNSL patients the overall response rate was 63% (CR+PR: 38%+25%). All responses were achievable with predictable toxicity mainly reflecting reversible myelosuppression. Conclusion: This study suggests that FTD could be an effective treatment for CNS lymphoma, and is worthy of further evaluation.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.15
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• pp.6041-6046
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• 2014

Objective: Liposarcoma (LPS) is the most common soft tissue sarcoma and accounts for approximately 20% of all mesenchymal malignancies, often occurring in deep soft tissue of retroperitoneal space. Accurate preoperative diagnosis is therefore necessary. We explored whether computed tomography (CT) could be used to differentiate between the various types of retroperitoneal liposarcoma (RPLS). Method: Forty-seven cases of RPLS, diagnosed surgically and histologically, were analyzed retrospectively. CT features were correlated with postoperative pathological appearance. Results: The study radiologist identified 29, 11, 2, 2 and 3 RPLS as atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL), dedifferentiated liposarcoma (DDL), myxoid/round cell liposarcoma (ML/RCL), pleomorphic liposarcoma (PL) and mixed-type liposarcoma. Analysis of CT scans revealed the following typical findings of the different subtypes of RPLS: ALT/WDL was mainly visible as a well-delineated fatty hypodense tumor with uniform density and integrity margin; DDL was marked by the combination of focal nodular density and hypervascularity. ML/RCL, PL and mixed liposarcoma showed malignant biological behaviour and CT findings need further studies. Conclusions: CT scanning can reveal important details including internal components, margins and surrounding tissues. Based on CT findings, tumor type can be roughly evaluated and biopsy location and therapeutic scheme guided.

• Molecules and Cells
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• v.37 no.8
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• pp.605-612
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• 2014

The p73 gene contains an extrinsic P1 promoter and an intrinsic P2 promoter, controlling the transcription of the pro-apoptotic TAp73 isoform and the anti-apoptotic ${\Delta}Np73$ isoform, respectively. The DNA methylation status of both promoters act equally in the epigenetic transcriptional regulation of their relevant isoforms. The aim of this study was to analyze the different effects of these p73 isoforms in 5-aza-2'-deoxycytidine (5-aza-dC)-induced apoptosis in breast cancer cells. We investigated the effects of the DNA demethylation agent, 5-aza-dC, on the T-47D breast cancer cell line, and evaluated the methylation status of the p73 promoters and expression of TAp73 and ${\Delta}Np73$. Furthermore, we assessed the expression of p53 and p73 isoforms in 5-aza-dC-treated T-47D cells and p53 knockout cells. 5-aza-dC induced significant anti-tumor effects in T-47D cells, including inhibition of cell viability, G1 phase arrest and apoptosis. This was associated with p73 promoter demethylation and a concomitant increase in TAp73 mRNA and protein expression. In contrast, the methylation status of promoter P2 was not associated with ${\Delta}Np73$ mRNA or protein levels. Furthermore, demethylation of P2 failed to inhibit the expression of ${\Delta}Np73$ with 5-aza-dC in the p53 knockdown cell model. Our study suggests that demethylation of the P1 and P2 promoters has opposite effects on the expression of p73 isoforms, namely up-regulation of TAp73 and down-regulation of ${\Delta}Np73$. We also demonstrate that p53 likely contributes to 5-aza-dC-induced ${\Delta}Np73$ transcriptional inactivation in breast cancer cells.

• The Journal of Dong Guk Oriental Medicine
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• v.7 no.1
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• pp.1-32
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• 1998

I found following idea, as a result of researching his Science idea, mainly, by translation of the "$Zh\bar{a}ng$ xi $ch\acute{u}n$ $Xu\acute{e}$ $Sh\acute{u}$ ssu $hsi\acute{a}ng$ "(張錫純 學術硏究). $Zh\bar{a}ng$ xi $ch\acute{u}n$ regarded $ch\tilde{u}ng$ $ch\bar{u}ng$ $ts'\bar{a}n$ $hs\bar{l}$' (衷中參西) as the core idea of The Chinese-Western medical combination. He didn't segregate philosophy of the West from One of the Orient. He persued to harmonize each other and thought that the Western medicint theory is included in the Chinese one in many parts. besides, He recognized that it is bad to reject each other, for the medical science's purpose is to save a life, and united The Chinese-Western medicine theory, by $ch\acute{u}ng$ $ch\tilde{u}ng$ $ch\bar{u}ng$ $ts'\bar{a}n$ $hs\bar{l}$'(衷中參西) idea which refers to consult the Western medicine on the basis of the Chinese one. Medical basic theory of $Zh\bar{a}ng$ xi $ch\acute{u}n$ brought up new views of the theory : Dae-gi(大氣), gi-Hwa(氣化) theory, Nongangubgan byung juing chi(論肝及肝病證治), Eum her chijung ja bi(陰虛治重滋脾). Lim Sangeung yong(臨床應用) of Hyul Her gub(血虛及)-Hwal Hyul Hwa $\breve{u}$ bub(活血化瘀法), on the basis of classics, such as, "$N\breve{e}i$ Ching"(內經), "Chin Kue $\breve{i}$ $y\bar{a}o$ $l\ddot{u}{\bar{e}}h$, "Shen $n\acute{u}ng$ $p\breve{e}n$ $t\acute{s}{\check{a}}o$ ching"(新農本草經) etc. I'll sum up $Zh\bar{a}ng$ xi $ch\acute{u}n's$ clinical idea now He unified Sang Han(像寒)-On Byung(溫病) with Yuk Kyung Byung Jung(六經辨證) and It was noticiable to utilize a kinds of Baek Ho Tang(白虎湯). He gave a detailed description about a method of grasp the symptoms of the cause of the internal medicine diseases and pathology and, he left abundant views of theory about using remedy and experience of clinic.

• Mycobiology
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• v.49 no.4
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• pp.406-420
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• 2021

Gloeostereum incarnatum has edible and medicinal value and was first cultivated and domesticated in China. We sequenced the G. incarnatum monokaryotic strain GiC-126 on an Illumina HiSeq X Ten system and obtained a 34.52-Mb genome assembly sequence that encoded 16,895 predicted genes. We combined the GiC-126 genome with the published genome of G. incarnatum strain CCMJ2665 to construct a genetic linkage map (GiC-126 genome) that had 10 linkage groups (LGs), and the 15 assembly sequences of CCMJ2665 were integrated into 8 LGs. We identified 1912 simple sequence repeat (SSR) loci and detected 700 genes containing 768 SSRs in the genome; 65 and 100 of them were annotated with gene ontology (GO) terms and KEGG pathways, respectively. Carbohydrate-active enzymes (CAZymes) were identified in 20 fungal genomes and annotated; among them, 144 CAZymes were annotated in the GiC-126 genome. The A mating-type locus (MAT-A) of G. incarnatum was located on scaffold885 at 38.9 cM of LG1 and was flanked by two homeodomain (HD1) genes, mip and beta-fg. Fourteen segregation distortion markers were detected in the genetic linkage map, all of which were skewed toward the parent GiC-126. They formed three segregation distortion regions (SDR1-SDR3), and 22 predictive genes were found in scaffold1920 where three segregation distortion markers were located in SDR1. In this study, we corrected and updated the genomic information of G. incarnatum. Our results will provide a theoretical basis for fine gene mapping, functional gene cloning, and genetic breeding the follow-up of G. incarnatum.