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검색결과 135건 처리시간 0.03초

Ciga-X inhibits nicotine-induced human lung fibroblasts cytotoxicity and craving for cigarettes

  • Kim, Mi-Sun;Jin, Jong-Sik;An, Hyo-Jin;Park, Do-Young;Park, Su-Jung;Kim, Hyeong-Kyun;Kim, Hyung-Min
    • Advances in Traditional Medicine
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    • 제2권2호
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    • pp.119-124
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    • 2002
  • Cigarette smoking contributes to lung cancer, cardiovascular diseases, oral diseases, etc. In desire to reduce their risk of disease, many cigarette smokers have tried to quit smoking. Sensory aspects of cigarette smoke are important for providing smoking satisfaction. Previously it was reported that citric acid aerosol significantly reduced craving for cigarettes and enhances smoking reduction and cessation. In this study, we tested whether a newly combined product Ciga-X, an aerosol for cessation aid, had toxicity in human embryonic lung fibroblast (MRC-9). The inhibitory effect of Ciga-X on cytotoxicity induced by cigarette smoke extract (CSE) or nicotine was examined in MRC-9, and craving for cigarettes and smorkers satisfaction after using Ciga-X was estimated. Ciga-X did not affect cell viability and had no toxicity in MRC-9. Ciga-X significantly inhibited not only CSE-induced cytotoxicity but also nicotine-induced cytotoxicity in MRC-9. One hundred and forty smokers rated the satisfaction for Ciga-X aerosol and craving reduction for cigarettes after using Ciga-X. The percentage of over 5 rating was 71.0% and 50.0% of subjects in satisfaction test for Ciga-X compared to their own brand and in craving reduction for cigarette, respectively. Besides, craving reduction for cigarette was highly correlated with the duration of smoking. Subjects have smoked under 10 years were more reduced in craving for cigarettes after using Ciga-X as compared to over 10 years (p=0.049). These results suggest that Ciga-X may be effective in promoting smoking abstinence with the reduction of CSE- or nicotine-induced human lung fibroblasts cytotoxicity.

휠체어에서 엉덩이 들기 동작 동안 발위치가 척수손상환자의 어깨 근활성도, 최대 족저압, 무릎굽힘 각도, 운동자각도에 미치는 효과 비교 (Comparison of the Effects of Different Foot Positions During Body-lifting in Wheelchair on Shoulder Muscle Activities, Peak Plantar Pressure, Knee Flexion Angle, and Rating Perceived Exertion in Individuals With Spinal Cord Injury)

  • 이왕재;임원빈;윤병구;이범석;이충휘
    • 한국전문물리치료학회지
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    • 제24권2호
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    • pp.1-8
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    • 2017
  • Background: Individuals with spinal cord injury (SCI) rely on their upper limbs for body-lifting activity (BLA). While studies have examined the electromyography (EMG) and kinematics of the shoulder joints during BLA, no studies have considered foot position during BLA. Objects: This study compared the effects of different foot positions during BLA on the shoulder muscle activities, peak plantar pressure, knee flexion angle, and rating perceived exertion in individuals with SCI. Methods: The study enrolled 13 mens with motor-complete paraplegic SCI, ASIA (American Spinal Injury Association) A or B. All subjects performed BLA with the feet positioned on the wheelchair footrest and on the floor independently. Surface EMG was used to collect data from the latissimus dorsi, pectoralis major, serratus anterior, and triceps brachii. The peak plantar pressure was measured using pedar-X and the knee flexion angle with Image J. Borg's rating perceived exertion scale was used to measure the physical activity intensity level. The paired t-test was used to compare the shoulder muscle activities, peak plantar pressure, knee flexion angle, and rating perceived exertion between the two feet positions during BLA. Results: The activity of the latissimus dorsi, pectoralis major, serratus anterior, and triceps brachii and rating perceived exertion decreased significantly and the peak plantar pressure and knee flexion angle increased significantly when performing BLA with the feet positioned on the wheelchair footrest compared with on the floor (p<.05). Conclusion: These findings suggest that individuals with SCI may perform BLA with the feet positioned on the wheelchair footrest for weight-relief lifting to decrease the shoulder muscle activities and the rating perceived exertion and to increase the peak plantar pressure and the knee flexion angle.

뜸요법이 생리통과 월경곤란증 및 일상생활수행에 미치는 효과 (Effect of Moxibustion Heat Therapy on Menstrual Cramps, Dysmenorrhea, and Activities of Daily Living)

  • 이인숙
    • 한국보건간호학회지
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    • 제18권1호
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    • pp.39-49
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    • 2004
  • The purpose of this study was to investigate the effect of moxibustion heat therapy(Koryo hand acupuncture) on menstrual cramps. dysmenorrhea and ADL. The experiment was carried out during the period from March 24 to April 30, 2003. The subjects in the study were drawn from female students attending two colleges in Chungcheongbuk-do and Kyunggi-do. Of all those subjects. 19 and 14 subjects were assigned to the experimental and the control groups respectively. The moxibustion heat therapy were performed three times a week, subjects were treated twice a time. Data was analyzed using SPSS/WIN10.0 by $x^2$test. Wilcoxon sign rank. and Wilcoxon rank sum test. The result of this study were as follows : 1) After moxibustion heat therapy. the graphic rating score of menstrual cramps was decreased significantly from 7.79(SD=1.22) to 4.47(SD=2.25) in experimental group(z=-3.731. p=.000). And there was significant difference in the change of graphic rating score of menstrual cramps between both groups(z=-3.637. p=.000). 2) After moxibustion heat therapy. the score of face rating scale of menstrual cramps was decreased significantly from 3.95(SD=0.71) to 2.32(SD=1.00) in experimental group(z=-3.457. p=.000). And there was significant difference in the change of face rating score between both groups(z=-2.713. p=.007). 3) After moxibustion heat therapy. the score of adjective labor pain rating scale rank (ALPRS) of menstrual cramps was decreased significantly from 23.63(SD=4.19) to 17.27(SD=6.34) in experimental group(z=-2.941. p=.001). But there was no significant difference in the change of adjective labor pain rating score(ALPRS) of menstrual cramps between both groups(z=-1.918. p=.059). 4) After moxibustion heat therapy. the score of dysmenorrhea was decreased significantly from 7.0(SD=2.89) to 5.26(SD=3.54) in experimental group(z=-2.183. p=.029). But there was no significant difference in the change of the score of dysmenorrhea between both groups(z =-1.555. p=.125). 5) After moxibustion heat therapy, the score of ADL difficulty was decreased significantly from 33.26(SD=4.58) to 28.83(SD=9.44) in experimental group(z=-3.552. p=.000). And there was significant difference in the change of score of difficulty of ADL between both groups(z=-4.110. p=.000). The above finding indicated that the moxibustion heat therapy showed a practical effect on reducing menstrual cramps, dysmenorrhea and ADL difficulty in female. Accordingly. we can adopt the moxibustion heat therapy as a useful intervention in the community nursing.

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피보험체계측치(被保險體計測値)의 평가(評價)에 관한 연구(硏究) 제4보(第4報) 표준체중(標準體重) (A Study on the Rating of the Insureds' Anthropometric Data IV. Standard Body Weight)

  • 임영훈
    • 보험의학회지
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    • 제4권1호
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    • pp.101-109
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    • 1987
  • The present study was undertaken to establish the standard body weight by height in Korean adults by using the actually measured heights and weights of a total of 5,496 insured persons who were examined medically at the Honam Medical Room of Dong Bang Life Insurance Company, Ltd. from January, 1983 to January, 1986. The results were as follows: 1. The linear regression equations to establish the standard body weight of Korean adults were as follows: In male, for $18{\sim}19$ age group, $y=7.272{\times}10^{-6}{\times}x^3+23.560$ for $20{\sim}29$ age group, $y=8.187{\times}10^{-6}{\times}x^3+22.031$ for $30{\sim}39$ age group, $y=8.627{\times}10^{-6}{\times}x^3+23.169$ for $40{\sim}49$ age group, $y=9.561{\times}10^{-6}{\times}x^3+20.994$ and for $50{\sim}59$ age group, $y=8.604{\times}10^{-6}{\times}x^3+23.801$ In female, for $18{\sim}19$ age group, $y=8.252{\times}10^{-6}{\times}x^3+18.920$ for $20{\sim}29$ age group, $y=7.715{\times}10^{-6}{\times}x^3+22.409$ for $30{\sim}39$ age group, $y=8.808{\times}10^{-6}{\times}x^3+21.439$ for $40{\sim}49$ age group, $y=9.691{\times}10^{-6}{\times}x^3+21.940$ and for $50{\sim}59$ age group, $y=12.500{\times}10^{-6}{\times}x^3+11.031$ 2. The standard age, height, and weight tables by author were presented with the aid of linear regression equations. 3. The values of standard body weight by height established by author reveal to be a little higher than those of other Korean reports through all age groups of both sexes, and reveal to be considerably similar, compared with those of the reports in Japan for fourth and sixth decade of female group.

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섬유조직염 환자의 우울에 미치는 변인 (The Factors Influencing on Depression of Patients for Fibromyalgia Syndrome)

  • 성기월;신임희;이경희
    • 대한간호학회지
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    • 제33권5호
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    • pp.609-617
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    • 2003
  • Purpose: The purpose of this study is to understand the depression of patients for Fibromyalgia Syndrome(FMS) and to identify the factors influencing depression. Method: The instruments used here are Beck Depression Inventory in depression, the Korean Rheumatology Health Association' instruments in Self-Efficacy. Also, Pain and Fatigue was measured by Visual Graphic Rating Scale. The subject of study is 76 outpatients diagnosing FMS from rheumatism specialists at C hospital in D city. The data has been collected from Sep. 1st to Sep. 30th in 2001. For the analysis of collected data, frequency analysis, independent t-test, analysis of variance, Pearson's correlation and multiple regression analysis were used for statistical analysis with SAS statistical program. Result: General characteristics showing statistically significant difference in depression were age, education, occupation, gender, exercise and sleep in the patients with FMS. Depression for the patients with FMS has negative correlation coefficients with Self-efficacy and ADL, and positive correlation coefficients with Pain and Fatigue. The suitable regression form resulting from the multiple regression analysis to investigate the influencing factors of depression for the partients with FMS was expressed by y =50.067 - 0.278x$_1$ + 1.320x$_2$ (x$_1$: Self-Efficacy x$_2$: Fatigue) and $R^2$ =0.427. Conclusion: The factors influencing on depression of patients for FMS was Self-Efficacy, ADL, Pain, and Fatigue. Further study needs to be done identify methods of overcoming and presentation of depression in FMS.

선박 추진축계의 2절 비틀림 진동에 기인한 주 기관 상부 구조 진동현상과 방진 대책 (Main Engine Upper Structural Vibration Phenomenon due to 2nd Node Torsional Vibration and Countermeasures on the Marine Propulsion System)

  • 이돈출;김준성;김진희
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2013년도 춘계학술대회 논문집
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    • pp.549-554
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    • 2013
  • For the past years, higher power rating 2 stroke super long stroke diesel engines having more than 8 cylinders and larger cylinder bore are installed mainly on very large containerships to save on fuel consumption. However, these engines are prone to X-mode vibration due to $2^{nd}$ node torsional vibration or the X-type moment, particularly because of the increase in total length and height. Recently, cases of excessive X-mode vibration often occurred on engine's major components. This vibration is manifested also as secondary vibration causing failure in engine-mount large structures. This study investigated the excitations caused by the $2^{nd}$ node propulsion shafting torsional vibration that influence X-mode vibration of the main engine and practical countermeasures are proposed. An 8RT-82RT-flex 8 cylinder engine and 11S90S-ME 11 cylinder engine for a container ship was used as research model.

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순수티타늄 용접재의 잔류응력분포에 관한 연구 (A Study on the Residual Stress Distribution of Pure Titanium Welding Material)

  • 최병기;장경천
    • 한국안전학회지
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    • 제19권4호
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    • pp.8-13
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    • 2004
  • The purpose of this paper is to investigate the welding residual stress distribution according to the constraint or non-constraint welding condition with titanium commonly using power station, aircraft, and ship. The measuring method of the residual stress was applied stress release rating method with strain gages and a potable strain meter. The x direction residual stress generally showed the tensile residual stress in case of res03int welding. On the other hand, the x direction residual stress under non-restraint welding were changed tensile stress into compressive stress on 15mm away from welding bead center. Also, the y direction residual stress generally showed the tensile residual stress in case of non-restraint welding and the y direction residual stress under restraint welding were changed tensile stress into compressive stress about 60mm away from welding bead center.

초전도 전력케이블의 교류손실 측정 (AC loss Measurement of Superconducting Power Cable)

  • 황시돌;현옥배;손송호;최형식
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2005년도 제36회 하계학술대회 논문집 A
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    • pp.524-526
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    • 2005
  • As a research activity of the project of "Verification Test of Superconducting Power Cable", we measured the AC loss of a short length superconducting power cable. The rating and the length of the cable were 22.9kV, 1,250A and 2.2m. The voltage taps for measuring the AC loss were attached to both ends of the conductor of the superconducting cable. Through the voltage taps and a lock-in amplifier we measured the in-phase component of the voltage($V_x$) with the load current(I). The AC loss was measured by multiplying the in-phase component of the voltage($V_x$) by the load current(I). The value of the AC loss of the superconducting power cable was 1.18W/m/phase/kA at 77.3K, 1atm.

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인공위성용 2.8GHz 국부발전기에 관한 연구 (Development of a 2.8 GHz Local Oscillator for the Communication Satellite)

  • Seong Joon Kweon;Seong Kyu Lim;Sang Woong Lee;Keuk Whan Ra
    • 전자공학회논문지A
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    • 제31A권5호
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    • pp.58-67
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    • 1994
  • In this paper, It was designed the 2.8GHz local oscillator which convert 14.5 14.8GHz uplink frequency to 11.7 12.0GHz downlink frequency by the receiving mixer on the communication satellite transponder according to the rating of domestic satellite. Mukunghwa 1. To prevent the variation of the communication channel bandwidth, it needs a high stability and low phase noise characteristics. So we designed to get the target frequencey by multipling the output signal from the crystal oscillator. We got the simplicity of the circuit by manufacturing the X4 multiplier with transistor which is ordinarily used as a device of a below X3 multiplier for the efficiency.

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미국 디젤기관차의 매연 배출기준과 비교한 국내 디젤기관차의 매연 배출 저감목표 설정 연구 (Study on the Establishment of Reduction Goals for Air Pollutants Emissions from Diesel Locomotives in Korea by Comparison with Emission Regulation in United States)

  • 박덕신;권순박;임인권;조영민
    • 한국철도학회:학술대회논문집
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    • 한국철도학회 2006년도 추계학술대회 논문집
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    • pp.152-157
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    • 2006
  • The air pollutant emission from the railroad diesel locomotive is still a significant environmental concern in many countries including Korea and Unites States. The emission characteristics of the railroad diesel locomotive were extensively studied in this study. Particulate matter (PM) and nitrogen oxides ($NO_x$) emitted from a large locomotive engine (2-cycle, 16-cylinder, and 3,000-horsepower) under various engine-rating conditions was analyzed with a scanning mobility particle sizer and a gas stack sampler by using a dilution tunnel. We could gain the emission values of 2.1 g/horsepower-hour for PM and 42.7 g/horsepower-hour for $NO_x$. We proposed the emission reduction goal of the railroad diesel locomotive for Korea in comparison with the regulation of United States.

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