• Biomolecules & Therapeutics
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• v.25 no.3
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• pp.231-238
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• 2017

Myelin is a specialized structure of the nervous system that both enhances electrical conductance and insulates neurons from external risk factors. In the central nervous system, polarized oligodendrocytes form myelin by wrapping processes in a spiral pattern around neuronal axons through myelin-related gene regulation. Since these events occur at a distance from the cell body, post-transcriptional control of gene expression has strategic advantage to fine-tune the overall regulation of protein contents in situ. Therefore, many research interests have been focused to identify RNA binding proteins and their regulatory mechanism in myelinating compartments. Fragile X mental retardation protein (FMRP) is one such RNA binding protein, regulating its target expression by translational control. Although the majority of works on FMRP have been performed in neurons, it is also found in the developing or mature glial cells including oligodendrocytes, where its function is not well understood. Here, we will review evidences suggesting abnormal translational regulation of myelin proteins with accompanying white matter problem and neurological deficits in fragile X syndrome, which can have wider mechanistic and pathological implication in many other neurological and psychiatric disorders.

• Bulletin of the Korean Space Science Society
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• 2008.04a
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• pp.24.3-24.3
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• 2008

• Journal of Astronomy and Space Sciences
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• v.33 no.3
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• pp.173-176
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• 2016

We report on a systematic analysis of the spin and superorbital modulations of the high-mass X-ray binary 4U 0114+650, which consists of the slowest spinning neutron star known. Utilizing dynamic power spectra, we found that the spin period varied dramatically during the RXTE ASM and Swift BAT observations. This variation consists of a long-term spin-up trend, and two ~1,000 day and one ~600 day random walk epochs previously, MJD 51,000, ~MJD 51,400-52,000, and ~MJD 55,100-56,100. We further found that the events appear together with depressions of superorbital modulation amplitude. This provides evidence of the existence of an accretion disk, although the physical mechanism of superorbital modulation remains unclear. Furthermore, the decrease of the superorbital modulation amplitude may be associated with the decrease of mass accretion rate from the disk, and may distribute the accretion torque of the neutron star randomly in time.

• KIPS Transactions on Software and Data Engineering
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• v.10 no.6
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• pp.243-250
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• 2021

With the increased development of 3D VR applications augmented by recent VR/AR/MR technologies and by the advance of 3D devices, interchangeability and portability of 3D data have become essential. 3D files should be processed in a standard data format for common usage between applications. Providing standardized libraries and data structures along with the standard file format means that a more efficient system organization is possible and unnecessary processing due to the usage of different file formats and data structures depending on the applications can be omitted. In order to provide the function of using a common data file and data structure, this research is intended to provide a programming binding tool for generating and storing standardized data so that various services can be developed by accessing the common 3D files. To achieve this, this paper defines a common data structure including classes and functions to access X3D files with a standardized scheme using the Python programming language. It describes the implementation of a Python language binding viewer, which is an X3D VR viewer for rendering standard X3D data files based on the language binding interface. The VR viewer includes Python based 3D scene libraries and a data structure for creation, modification, exchange, and transfer of X3D objects. In addition, the viewer displays X3D objects and processes events using the libraries and data structure.

• Korean Journal of Culture and Social Issue
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• v.26 no.3
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• pp.195-220
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• 2020

The purpose of this study was to validate the Korean version of the post-traumatic growth inventory-expanded(K-PTGI-X), which has been widely used to assess posttraumatic growth. The PTGI-X is a measure of the addition of the items to measure the existential growth as the need for modification to the factors of the 'increase of spiritual interest' in the existing PTGI is suggested. We examined the factor structure, reliability, and validity of a Korean version of the PTGI-X among 625 Korean adults who have experienced trauma events. First, EFA confirmed the appropriate PTGI-X factor structure and found that the 4-factor structure was the most appropriate. Next, as a result of CFA, it was found that the model to which correlation between items was added to the 4-factor model was good. Next, testing internal consistency, CR, and AVE of the K-PTGI-X showed that PTGI-X's items are reliable. Also, we tested the concurrent validity and discriminative validity. All of the K-PTGI-X scales significantly correlated with measures of deliberate rumination and core-belief except for the intrusive rumination. Finally, to add an understanding of K-PTGI-X, t-test according to demographic variables was conducted. Recommendations for future research and implications were discussed.

• Journal of The Korean Astronomical Society
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• v.40 no.4
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• pp.99-106
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• 2007

Statistical analyses were performed to investigate the relative success and accuracy of daily maximum X-ray flux (MXF) predictions, using both multilinear regression and autoregressive time-series prediction methods. As input data for this work, we used 14 solar activity parameters recorded over the prior 2 year period (1989-1990) during the solar maximum of cycle 22. We applied the multilinear regression method to the following three groups: all 14 variables (G1), the 2 so-called 'cause' variables (sunspot complexity and sunspot group area) showing the highest correlations with MXF (G2), and the 2 'effect' variables (previous day MXF and the number of flares stronger than C4 class) showing the highest correlations with MXF (G3). For the advanced three days forecast, we applied the autoregressive timeseries method to the MXF data (GT). We compared the statistical results of these groups for 1991 data, using several statistical measures obtained from a $2{\times}2$ contingency table for forecasted versus observed events. As a result, we found that the statistical results of G1 and G3 are nearly the same each other and the 'effect' variables (G3) are more reliable predictors than the 'cause' variables. It is also found that while the statistical results of GT are a little worse than those of G1 for relatively weak flares, they are comparable to each other for strong flares. In general, all statistical measures show good predictions from all groups, provided that the flares are weaker than about M5 class; stronger flares rapidly become difficult to predict well, which is probably due to statistical inaccuracies arising from their rarity. Our statistical results of all flares except for the X-class flares were confirmed by Yates' $X^2$ statistical significance tests, at the 99% confidence level. Based on our model testing, we recommend a practical strategy for solar X-ray flare predictions.

• Journal of Korean Society for Atmospheric Environment
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• v.26 no.2
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• pp.161-176
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• 2010

We examined high ozone episodes observed during the intensive measurement periods (11 May~21 June and 30 July~11 August 2009) in the Gulf of Gwangyang. During that period, there were a few events (or days) in which 1 hr averaged ozone concentrations were greater than 100 ppbv. The analysis of ozone budget and photochemical characteristics related to the ozone production was carried out using a photochemical box model. Ozone sensitivity to $NO_x$ and VOCs was also examined in the study area during the measurement period. Diurnal variation of ozone during the episodes was similar to that of odd hydrogen radicals ($HO_2,CH_3O_2$, and $RO_2$), suggesting significant correlation with photochemical production of ozone during the episodes. In general, ozone concentration in the study area during the measurement period was sensitive to VOCs, whereas ozone was sensitive to $NO_x$ under certain conditions. Ozone sensitivity assessment using a radical budget analysis and $NO_x$/VOCs-control strategy was consistent with that using indicator species ($H_2O_2/HNO_3$ ratio).

• Journal of Space Technology and Applications
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• v.3 no.1
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• pp.1-25
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• 2023

In this paper, I briefly introduce recently terminated, current, and future scientific spacecraft missions for in situ and remote-sensing observations of Earth's and other planetary magnetospheres as of February 2023. The spacecraft introduced here are Geotail, Cluster, Time History of Events and Macroscale Interactions during Substorms / Acceleration, Reconnection, Turbulence, and Electrodynamics of the Moon's Interaction with the Sun (THEMIS / ARTEMIS), Magnetospheric Multiscale (MMS), Exploration of energization and Radiation in Geospace (ERG), Cusp Plasma Imaging Detector (CuPID), and EQUilibriUm Lunar-Earth point 6U Spacecraft (EQUULEUS) for recently terminated or currently operated missions for Earth's magnetosphere; Lunar Environment Heliospheric X-ray Imager (LEXI), Gateway, Solar wind Magneto-sphere Ionosphere Link Explorer (SMILE), HelioSwarm, Solar-Terrestrial Observer for the Response of the Magnetosphere (STORM), Geostationary Transfer Orbit Satellite (GTOSat), GEOspace X-ray imager (GEO-X), Plasma Observatory, Magnetospheric Constellation (MagCon), self-Adaptive Magnetic reconnection Explorer (AME), and COnstellation of Radiation BElt Survey (CORBES) approved for launch or proposed for future missions for Earth's magnetosphere; BepiColombo for Mercury and Juno for Jupiter for current missions for planetary magnetospheres; Jupiter Icy Moons Explorer (JUICE) and Europa Clipper for Jupiter, Uranus Orbiter and Probe (UOP) for Uranus, and Neptune Odyssey for Neptune approved for launch or proposed for future missions for planetary magnetospheres. I discuss the recent trend and future direction of spacecraft missions as well as remaining challenges in magnetospheric research. I hope this paper will be a handy guide to the current status and trend of magnetospheric missions.

• International Journal of Concrete Structures and Materials
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• v.10 no.sup3
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• pp.87-96
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• 2016

This numerical study investigated the effects of different reinforcing details in beam-column joints on the blast resistance of the joints. Due to increasing manmade and/or natural high rate accidents such as impacts and blasts, the resistance of critical civil and military infrastructure or buildings should be sufficiently obtained under those high rate catastrophic loads. The beam-column joint in buildings is one of critical parts influencing on the resistance of those buildings under extreme events such as earthquakes, impacts and blasts. Thus, the details of reinforcements in the joints should be well designed for enhancing the resistance of the joints under the events. Parameters numerically investigated in this study include diagonal, flexural, and shear reinforcing steel bars. The failure mechanism of the joints could be controlled by the level of tensile stress of reinforcing steel bars. Among various reinforcing details in the joints, diagonal reinforcement in the joints was found to be most effective for enhancing the resistance under blast loads. In addition, shear reinforcements also produced favourable effects on the blast resistance of beam-column joints.

• The Bulletin of The Korean Astronomical Society
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• v.43 no.1
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• pp.56.1-56.1
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• 2018

Tidal disruption events (TDEs) provide evidence for quiescent supermassive black holes (SMBHs) in the centers of inactive galaxies. TDEs occur when a star on a parabolic orbit approaches close enough to a SMBH to be disrupted by the tidal force of the SMBH. The subsequent super-Eddington accretion of stellar debris falling back to the SMBH produces a characteristic flare lasting several months. The theoretically expected bolometric light curve decays with time as proportional to $t^{-5/3}$. However, the light curves observed in most of the optical-UV TDEs deviate from the $t^{-5/3}$ decay rate especially at early time, while the light curves of some soft-X-ray TDEs are overall in good agreement with the $t^{-5/3}$ law. Therefore, it is required to construct the theoretical model for explaining these light curve variations consistently. In this paper, we revisit the mass fallback rates analytically and semi-analytically by taking account of the structure of the star, which is simply modeled by the polytrope. We find the relation between a polytropic index and the power law index of the mass fallback rate. We also discuss whether and how the decay curves, which we derived, fit the observed ones.