• Mycobiology
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• v.43 no.3
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• pp.272-279
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• 2015

To screen molecular chaperones similar to small heat shock proteins (sHsps), but without ${\alpha}$-crystalline domain, heat-stable proteins from Schizosaccharomyces pombe were analyzed by 2-dimensional electrophoresis and matrix assisted laser desorption/ionization time-of-flight mass spectrometry. Sixteen proteins were identified, and four recombinant proteins, including cofilin, NTF2, pyridoxin biosynthesis protein (Snz1) and Wos2 that has an ${\alpha}$-crystalline domain, were purified. Among these proteins, only Snz1 showed the anti-aggregation activity against thermal denaturation of citrate synthase. However, pre-heating of NTF2 and Wos2 at $70^{\circ}C$ for 30 min, efficiently prevented thermal aggregation of citrate synthase. These results indicate that Snz1 and NTF2 possess molecular chaperone activity similar to sHsps, even though there is no ${\alpha}$-crystalline domain in their sequences.

• Korean Journal of Poultry Science
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• v.34 no.3
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• pp.173-180
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• 2007

This study was conducted to evaluate conjugated linoleic acid (CLA) precursor and produce supplementation on egg production, egg quality and blood immunological parameters in laying hens. The total of 252 (32-wk) Hy-line brown commercial hens were used for 5 weeks. Dietary treatments included 1) CON (basal diet + oat 1% + soybean oil 1%), 2) WOS (basal diet + whey 0.5% + oat 0.5% + soybean oil 1%), 3) WS (basal diet+ whey 1% + soybean oil 1%), 4) WOCLA (basal diet + whey 0.5% + oat 0.5% + CLA produce 1%), 5) WCLA (basal diet + whey 1% + CLA produce 1%) and 6) FOCLA (basal diet + Fish oil 0.5% + oat 1% + CLA produce 0.5%). For 4 weeks egg shell thickness was higher in WOS and FOCLA treatments than WOCLA and WCLA treatments (P<0.05). Egg weight was significantly increased (P<0.05) in WOS and FOCLA treatments compared to WS and WCLA treatments for 4 weeks. From 4 to 5 weeks yolk high, yolk color and haugh unit were significantly higher in FOCLA treatment than CON treatment (P<0.05). IgG concentration of blood was increased in WOS and FOCLA treatments compared to CON, WS and WOCLA treatments(P<0.05). In conclusion, fish oil, CLA produce and oat supplementation in laying hens diet improve egg shell thickness, yolk high, yolk color and haugh unit, also, CLA precursor supplementaion in laying hens diet improve IgG concentration of blood higher than CON treatment.

• Bulletin of the Korean Chemical Society
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• v.11 no.6
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• pp.531-534
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• 1990

The reaction of $Os_3(CO)_{10}(NCMe)_2$ with a tungsten alkylidyne $Cp(CO)_2W{\equiv}CTol(Cp={\eta}^5-C_5H_5,\;Tol=p-C_6H_4Me)$ produces the compound, $CpWOs_3(CO)_{11}({\mu}_3-CTol)$(1). The structure of compound 1 can be viewed as one in which the metalla-alkyne, $Cp(CO)_2W{\equiv}CTol$, is ${\mu}_3-{\eta}^2-{\bot}$ (perpendicular) bound to an $Os_3(CO)_9$ fragment. Variable-temperature $^{13}C$ NMR spectra of 1 show no evidence for the analogous rotation of the metalla-alkyne molecule as shown alkyne rotation in $Os_3(CO)_9(C_2Tol_2)$ compound. This lack of the metalla-alkyne fluxionality supports the apparent saturated nature of compound 1.

• The Journal of the Korea Contents Association
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• v.22 no.5
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• pp.576-584
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• 2022

As an important branch of cognitive psychology, "constructivism" is called a "revolution" in contemporary educational psychology, which has a profound influence on the field of pedagogy and psychology. Based on "WOS" database, this study selects "WOS Core database" and "KCI database", uses CiteSpace visualization software as analysis tool, and makes knowledge map analysis on the research literature of "constructivism" in the field of education in recent 35 years. Analysis directions include annual analysis, network connection analysis by country(region) branch, author, institution or University, and keyword analysis. The purpose of the analysis is to grasp the subject areas, research hotspots and future trends of the research on constructivism, and to provide theoretical reference for the research on constructivism. There are three conclusions from the study. 1. Studies on the subject of constructivism have continued from the 1980s to the present. It is now in a period of steady development. 2. Countries concerned with the subject of constructivism mainly include the United States, Canada, Britain, Australia and the Netherlands. The main research institutions and authors are mainly located in these countries. 3. Currently, the keywords constructivism research focus on the clusters of "instructional strategies", and the development of science and technology is affecting individual learning. In the future, instructional strategies will become the focus of structural constructivism research. With the development of instructional technology, it is necessary to conduct research related to the development of new teaching models.

• The Journal of Korean Academy of Prosthodontics
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• v.17 no.1
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• pp.61-66
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• 1979

To investigate the variation of the mandibular rest position according to time, the mandibular rest position was induced by combination of relaxation and swallowing method. The displacement of the incisal point was recorded with the pinpointed miniature lamp luminograph in three dimensions immediately, 30 seconds, and 60 seconds after induction of the mandibular rest position. The Results obtained were as follows 1. Intermaxillary vertical distance measured immediately after induction of mandibur rest position ranged from 1.0mm to 3.9mm And it varied irregularly with time, ranging from 0.1mm to 1.1mm Anteroposterior variance with time ranged irregularly from 0.2mm to 0.8mm 2. The mandibular rest position observed in the frontal plane varied with time to right or left direction, ranging from 0.2mm to 0.5mm from the centric occlusion 3. the mandibular rest position wos not placed definite position but varied spatially in certain range with time.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.7
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• pp.3139-3145
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• 2016

Cancer is the leading cause of morbidity and mortality worldwide, characterized by irregular cell growth. Cytotoxicity or killing tumor cells that divide rapidly is the basic function of chemotherapeutic drugs. However, these agents can damage normal dividing cells, leading to adverse effects in the body. In view of great advances in cancer therapy, which are increasingly reported each year, we quantitatively and qualitatively evaluated the papers published between 1981 and December 2015, with a closer look at the highly cited papers (HCPs), for a better understanding of literature related to cytotoxicity in cancer therapy. Online documents in the Web of Science (WOS) database were analyzed based on the publication year, the number of times they were cited, research area, source, language, document type, countries, organization-enhanced and funding agencies. A total of 3,473 publications relevant to the target key words were found in the WOS database over 35 years and 86% of them (n=2,993) were published between 2000-2015. These papers had been cited 54,330 times without self-citation from 1981 to 2015. Of the 3,473 publications, 17 (3,557citations) were the most frequently cited ones between 2005 and 2015. The topmost HCP was about generating a comprehensive preclinical database (CCLE) with 825 (23.2%) citations. One third of the remaining HCPs had focused on drug discovery through improving conventional therapeutic agents such as metformin and ginseng. Another 33% of the HCPs concerned engineered nanoparticles (NPs) such as polyamidoamine (PAMAM) dendritic polymers, PTX/SPIO-loaded PLGAs and cell-derived NPs to increase drug effectiveness and decrease drug toxicity in cancer therapy. The remaining HCPs reported novel factors such as miR-205, Nrf2 and p27 suggesting their interference with development of cancer in targeted cancer therapy. In conclusion, analysis of 35-year publications and HCPs on cytotoxicity in cancer in the present report provides opportunities for a better understanding the extent of topics published and may help future research in this area.

• Korean Journal of Environmental Agriculture
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• v.13 no.1
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• pp.39-46
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• 1994

Two types of sunshine recorders, Jordan and bimetal, were used for measuring the duration of sunshine and percentage of sunshine in Weather Forecast Offices(WFO) and Weather Observation Stations(WOS) in Korea, respectively.These two gauges showed different values in each element observation. To evaluate the solar energy resources by duration and percentage of sunshine, relevant parameter should be adapted to use the two kinds of data for zoning of agricultural climatic area and comparison of regional solar energy distributions. In this respect, the correlation and distribution pattern were found by analyzing data from the two types of sunshine recorders. The results were as follows. The monthly duration of sunshine by the Jordan type was $50{\sim}60$ hours lower than the bimetal type and its value in May was the highest in a year. The percentage of sunshine by the Jordan type was $5{\sim}10%$ lower than the bimetal type. The seasonal difference of sunshine hour data by two types of sunshine recorder became small in winter but large in summer. Standard deviation of monthly duration of sunshine of WFO and WOS was $11{\sim}32$ and $17{\sim}25$ hours and percentage of sunshine was $3{\sim}11$ and $4{\sim}9$ % respectively. The range of deviation in WOS data was smaller than WFO. The highest distribution of duration and percentage of sunshine was in the Southern Coastal Area, whereas the lowest in the Central North Western Area.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.18 no.2
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• pp.21-34
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• 2023

The purpose of this study is to examine the extent of Sustainable Development Goals (SDGs)-related research in the field of entrepreneurship globally since the adoption of the SDGs at the UN General Assembly, and to compare international and domestic research trends in order to determine the direction of SDGs-related research in entrepreneurship in Korea. Utilizing three databases-Web of Science (WoS), KCI, and DBpia- SDGs-related studies in entrepreneurship were extracted by employing specific search terms. After data purification, a total of 356 studies abroad and 4 studies in Korea were used for analysis. After data purification, a total of 356 international studies and 4 Korean studies were analyzed. Due to the limited number of domestic studies, the research trends were examined by conducting frequency analysis and keyword network analysis on international studies alone. Frequency analysis revealed that SDGs research in entrepreneurship primarily focused on sustainability-related terms and was conducted in conjunction with business models, innovation, entrepreneurship education, and strategies. Furthermore, yearly frequency analysis demonstrated an expansion of topics to encompass research on entrepreneurship and SDGs policies, the roles and capabilities of female entrepreneurs in SDGs implementation, energy start-ups and SDGs, directions for implementing SDGs in business schools and SDGs education, indicators for SDGs implementation and evaluation, and technologies for sustainability. The keyword network analysis identified central topics such as business, sustainability, SDGs, innovation, entrepreneurship, business models, and education, with research areas extending to entrepreneurship ecosystems, change and strategy, ethics, and climate. This study holds significance in establishing a foundation for SDGs research in entrepreneurship, which is currently an underexplored area in Korea, by presenting emerging research trends related to SDGs in entrepreneurship.