• Journal of The Korean Society of Clinical Toxicology
• /
• v.3 no.1
• /
• pp.56-59
• /
• 2005

Blister beetles produce cantharidin, which is toxic to people and animals. Cantharidin has been believed to be an aphrodisiac and an abortifacient based on its tendency to cause marked irritation to the genitourinary system leading to priapism in men and pelvic congestion in women for many years. Cantharidin was used by oriental traditional medicine for more than 2000 years. Typical signs related to cantharidin ingestion are gastrointestinal tract and urinary tract irritation, endotoxemia, shock and myocardial dysfunction. Cantharidin is a severe irritant to epithelial linings (gastrointestinal tract, urinary tract, and skin) and develop systemic inflammatory response syndrome. We report a case of corrosive esophagogastritis and acute renal failure by ingestion of cantharidin.

• Tuberculosis and Respiratory Diseases
• /
• v.52 no.5
• /
• pp.539-544
• /
• 2002

Primary lung cancer can metastasize by a direct local extension, hematogenous dessemination, and lymphatic spread. However, it less commonly metastasizes via a transbronchial invasion. Approximately half of all patients with lung cancer have metastases at the initial presentation. Autopsy data showed that there are an average of 4.8 metastatic sites. The most common sites for metastases include the lymph nodes, liver, adrenal gland, bone, and brain. However clinically significant metastases isolated in the small bowel seldom occur. Here we report a case of lung cancer with a small bowel metastasis.

• Biomedical Science Letters
• /
• v.24 no.3
• /
• pp.275-279
• /
• 2018

Inflammatory bowel disease (IBD) is increasing in prevalence in developed countries but the cause of this increase is unclear. In animal models of IBD and in human IBD patients, alterations in the tight junctional proteins have been observed, suggesting that the intestinal microflora may penetrate the underlying colonic tissue and promote inflammation. Enterotoxigenic Bacteroides fragilis (ETBF) causes inflammatory diarrhea in human and is implicated in inflammatory bowel diseases. However, it is unclear whether alterations in tight junctional proteins occur during ETBF infection in mice. In this brief communication, we report that ETBF infection induces up-regulation of claudin-2 and down-regulation of claudin-5 through B. fragilis toxin (BFT) activity in the large intestine of C57BL/6 mice. In contrast, BFT did not induce changes in tight junctional proteins in the HT29/C1 cell line, suggesting that analysis of biological activity of BFT in vivo is important for evaluating ETBF effects.

• Journal of The Korean Society of Clinical Toxicology
• /
• v.2 no.1
• /
• pp.63-66
• /
• 2004

Hydrofluoric acid (HF), one of the strongest inorganic acids, is used mainly for industrial purpose. Hydrofluoric acid injuries has a potential for both systemic as well as severe local tissue destruction. One of the most serious consequences of severe exposure to HF by any route is marked lowering of serum calcium (hypocalcemia) and other metabolic changes, such as hypomagnesemia and which may result in a fatal outcome if not recognized and treated. promptly cardiotoxicity is not well known except arrhythmias, which are a primary cause of death. We report a case of myopericarditis by ingestion of hydrofluoric acid.

• Proceedings of the Korean Society of Computer Information Conference
• /
• 2019.01a
• /
• pp.129-131
• /
• 2019

본 논문에서는 다양한 아두이노 무선센서 모듈과 Raspberry Pi, 웹서버를 이용한 IOT 기반 환경정보 수집 시스템을 구현하고, 상품추천시스템을 제안한다. 이 시스템은 사용자가 주변 환경의 데이터를 정확하게 확인하고 활용할 수 있도록 한다. 상품추천 시스템에서는 상점 외부에 부착된 다양한 무선센서 모듈들을 이용해 상점 주변의 환경데이터를 수집하고, 무선통신을 통해 Raspberry Pi로 데이터를 전송한다. 전송된 데이터는 Server로 보내져 Server DB에 저장되고 Server에서 센서값들의 평균값을 계산해 Raspberry Pi로 다시 보내주면 Raspberry Pi에 연결된 모니터를 통해 실시간으로 주변의 데이터와 주변 상황에 맞는 경고 메시지를 보여주고, 이후 필요한 물건을 추천해준다.

• Journal of Microbiology and Biotechnology
• /
• v.29 no.9
• /
• pp.1361-1368
• /
• 2019

Codium fragile is an edible seaweed in Asian countries that has been used as a thrombolytic, anticoagulant, antioxidant, anti-inflammatory, and immune-stimulatory agent. Ginseng has also been known to maintain immune homeostasis and to regulate the immune system via enhancing resistance to diseases and microorganisms. In this study, anionic macromolecules extracted from C. fragile (CFAM) were orally administered with red ginseng extract (100 mg/kg body weight) to cyclophosphamide-induced immunosuppressed male BALB/c mice to investigate the immune-enhancing cooperative effect of Codium fragile and red ginseng. Our results showed that supplementing CFAM with red ginseng extract significantly increased spleen index, T- and B-cell proliferation, NK cell activity, and splenic lymphocyte immune-associated gene expression compared to those with red ginseng alone, even though a high concentration of CFAM with red ginseng decreased immune biomarkers. These results suggest that CFAM can be used as a co-stimulant to enhance health and immunity in immunosuppressed conditions.

• Proceedings of the Korean Society of Computer Information Conference
• /
• 2021.07a
• /
• pp.723-725
• /
• 2021

도로 이용자의 교통정보에 대한 수요 증가와 효율적인 도로 이용을 위해, 또한 지능형 교통체계(ITS, Intelligent Transport Systems)의 기본 기술로서 교통정보를 수집하여 제공하는 시스템에 대한 개발과 요구가 지속되고 있다. 본 연구에서는 고속도로에서 가장 많이 사용하는 교통정보 수집도구인 차량감지기(VDS)를 활용한 교통 정보 수집 시스템에 관하여 조사하였다. 이러한 차량 검지기를 활용한 교통정보는 차량의 속도와 교통량을 산출하는 데에는 효율적이지만, 공사와 수집 장비 불량으로 인하여 모든 교통 정보를 수집하는데 어려움이 있다. 이로 인해 전체적인 교통상황을 파악하기 위한 새로운 시도와 알고리즘 개발이 요구된다.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2023.11a
• /
• pp.285-286
• /
• 2023

우리 나라는 오래 전부터 민방위 차원에서 각 지역에 대피소를 선정해두고 정부 해당 부처의 게시판으로 알리고 있다. 그러나, 민방위 훈련이 거의 실시되지 않는 터라 대부분의 국민들은 어느지역에 어떤 대피소가 마련되어 있는지 알지 못한다. 최근에는 민방위 뿐만 아니라 바닷가 해일에 대비하기 위한 대피소도 늘어나고 있는데 이를 알고 있는 국민 또한 많지 않다. 따라서 이 연구에서는 현재 위치 주변에 어떤 대피소가 있는지와 가장 가까운 대피소까지의 길을 안내하는 긴급 대피소 안내 앱을 개발한다. 그 외에 이 앱은 지역별로 최근 발송된 재난 문자를 검색하는 기능도 제공한다.

• Tuberculosis and Respiratory Diseases
• /
• v.63 no.6
• /
• pp.515-520
• /
• 2007

Mycoplasma pneumoniae (M. pneumoniae) is the leading cause of pneumonia in older children and young adults. Normally, it does not progress to a condition requiring hospitalization but improves spontaneously or has a mild clinical course. We report two cases of M. pneumoniae pneumonia with different clinical manifestations from the normal course. The patients were young healthy individuals. The diagnoses were made by serology. However, it could not be determined beforehand that they had M. pneumoniae pneumonia. Based on the empirical treatment strategy of severe community acquired pneumonia, the patients were treated with broad-spectrum antibiotics including cephalosporin, quinolone and macrolide. After administering the antibiotics, they showed a gradually favorable clinical course and recovered without residual complications. A M. pneumoniae infection should be considered as a cause of severe community acquired pneumonia, and empirical treatment targeting this organism might be helpful in treating patients with the severe manifestation.

• 대한예방의학회:학술대회논문집
• /
• 2001.10a
• /
• pp.159-160
• /
• 2001