Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)

Korean society of Clincal Toxicology (대한임상독성학회)
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A Case of Cantharidin Poisoning after the Ingestion of Herbal Medicine

한약복용 후 발생한 칸타리딘 중독 1례

  • Ji Ho Jin (Department of Emergency Medicine, Wonju College of Medicine,Yonsei University) ;
  • Kim Hyun (Department of Emergency Medicine, Wonju College of Medicine,Yonsei University) ;
  • Kim Sun Hyu (Department of Emergency Medicine, Wonju College of Medicine,Yonsei University) ;
  • Oh Sung Bum (Department of Emergency Medicine, Wonju College of Medicine,Yonsei University) ;
  • Moon Joong Bum (Department of Emergency Medicine, Wonju College of Medicine,Yonsei University) ;
  • Lee Kang Hyun (Department of Emergency Medicine, Wonju College of Medicine,Yonsei University) ;
  • Hwang Sung Oh (Department of Emergency Medicine, Wonju College of Medicine,Yonsei University)
  • 지호진 (연세대학교 원주의과대학 응급의학교실) ;
  • 김현 (연세대학교 원주의과대학 응급의학교실) ;
  • 김선휴 (연세대학교 원주의과대학 응급의학교실) ;
  • 오성범 (연세대학교 원주의과대학 응급의학교실) ;
  • 문중범 (연세대학교 원주의과대학 응급의학교실) ;
  • 이강현 (연세대학교 원주의과대학 응급의학교실) ;
  • 황성오 (연세대학교 원주의과대학 응급의학교실)
  • Published : 2005.06.01
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Abstract

Blister beetles produce cantharidin, which is toxic to people and animals. Cantharidin has been believed to be an aphrodisiac and an abortifacient based on its tendency to cause marked irritation to the genitourinary system leading to priapism in men and pelvic congestion in women for many years. Cantharidin was used by oriental traditional medicine for more than 2000 years. Typical signs related to cantharidin ingestion are gastrointestinal tract and urinary tract irritation, endotoxemia, shock and myocardial dysfunction. Cantharidin is a severe irritant to epithelial linings (gastrointestinal tract, urinary tract, and skin) and develop systemic inflammatory response syndrome. We report a case of corrosive esophagogastritis and acute renal failure by ingestion of cantharidin.

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