• 제목/요약/키워드: Women Infertility

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동결보존 배아이식에서 분비기 자궁내막 유도시 프로게스테론 투여 방법에 따른 착상율과 임신율의 비교 (Implantation Rate and Clinical Pregnancy Rate According to Dosage and Timing of Progesterone Administration for Secretory Endometrial Preparation in Frozen-Thawed Embryo Transfer Cycles)

  • 박찬우;허걸;김문영;송현정;김혜옥;양광문;김진영;송인옥;유근재;천강우;변혜경;궁미경;강인수
    • Clinical and Experimental Reproductive Medicine
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    • 제30권3호
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    • pp.193-202
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    • 2003
  • Objective: To evaluate the difference of implantation rate (IR) and clinical pregnancy rate (CPR) between two protocols of endometrial preperation in women undergoing frozen-thawed embryo transfer (FET) cycles. Methods: This study was performed during the different time periods: A retrospective study from January 2000 to June 2001 (phase I) and a prospective study from July 2001 to March 2002 (phase II). All the patients received estradiol valerate (6 mg p.o. daily) starting from day 1 or 2 of the menstrual cycle without pituitary down regulation. Progesterone was administered around day 14 after sonographic confirmation of endometrial thickness $\geq$7 mm and no growing follicle. In Group A (n=88, 99 cycles) of phase I, progesterone was administered i.m. at a dose of 50 mg daily from one day prior to thawing of pronuclear (PN) stage frozen embryo or three days prior to thawing of 6-8 cell stage frozen embryo and then each stage embryos were trasnsferred 2 days or 1 day later after thawing. In Group B (n=246, 299 cycles) of phase I, patients recieved progesterone 100 mg i.m. from one day earlier than group A; two days prior to PN embryo thawing, four days prior to of 6-8 cell embryo thawing. During the phase II, to exclude any differences in embryo transfer procedures, in Group 1 (n=23, 28 cycles) of phase II embryo was transfered by one who have used the progesterone protocol since the phase I. In Group 2 (n=122, 139 cycles) of phase II embryo was transfered by one who use the progesterone protocol from the phase II. Results: When compared across the phase and group, there were no significant differences in the characteristics. During the phase I, there were significant increase in IR (14.4% vs 5.9%, p=0.001) and CPR (28.3% vs 14.5%, p=0.000) in group A. During the phases II, IR (11.8% vs 10.6%) and CPR (27.6% vs 27.3%) show no differences between two groups. Conclusions: In FET cycles, IR and CPR are increased significantly by the change of dosage and timing of progesterone administraton. And the timing is considered to be more important factor because the dosage of progesterone did not affect implantation window in previous studies. Therefore, we suggest that progesterone administration in FET cycle should begin from one day prior to PN stage embryo thawing and three days prior to 6-8 cell stage embryo thawing.

한국인 조기 난소부전 불임환자에서 황체형성 호르몬 유전자 변이 분석 (The Analysis of $LH{\beta}$-subunit Variants in Infertile Patients with Premature Ovarian Failure (POF) in Korea)

  • 김남근;이유진;남윤성;이숙환;전혜선;박찬;김종욱;이경아;고정재;차광열
    • Clinical and Experimental Reproductive Medicine
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    • 제27권2호
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    • pp.179-182
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    • 2000
  • This study was performed to determine whether the $LH{\beta}$-subunit gene missense mutation is present in Korean infertile patients with 46,XX POF women. The variants of $LH{\beta}$ exon 2 (Trp 8Arg; TGG to CGG and Ile15Thr; ATC to ACC) were studied in forty-four 46,XX idiopathic POF and 54 nonpregnant women. The $LH{\beta}$ exon 2 variants were more frequent in POF patients (20.5%) than nonpregnant (16.7%) women (p>0.05). POF patients with the variant was slightly higher than nonpregnant women with the variant.

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불임경험의 사회적 기제(Mechanism)와 간호 (Socio-Cultural Mechanism of Infertile Women's Experience and Nursing)

  • 조남옥;박영숙
    • 여성건강간호학회지
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    • 제2권2호
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    • pp.216-229
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    • 1996
  • Pregnancy and delivery are the God's blessing as well as the right of all married women. But, these are agonizing events for the infertile women. Therefore, supportive nursing care for the infertile women is crucial in the process of diagnosis and treatment of infertility. The introduction of In Vitro Fertilization is a solution for infertility. But we take it serious that such socio-cultural factors as patriarchism, sex role, and motherhood are negatively influencing infertility women's experiences. Thus, nurses who take care of the infertile women need to have feministic perspectives as well as medical information, and expertise so that they could reach a comprehensive understanding on infertile women's experiences.

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제천시 한방 난임 치료 지원 사업에 관한 연구 (A Study Assessing Support Project of Korean Medical Treatment in Infertility in Jecheon)

  • 남은영;유수정;김형준
    • 대한한방부인과학회지
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    • 제28권2호
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    • pp.120-132
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    • 2015
  • Objectives : This study aims to assess whether Korean medical treatment in infertile couple is effective on clinical pregnancy. Methods : Korean medical treatment using herbal medicine, acupuncture and moxibustion was performed to thirty-one women and one man of infertility from March 2013 to April 2015. Results : After the treatment, nine patients (eight women and 1 man) of infertility became pregnant (28.13%) in thirty-two patients. In nine patients with pregnancy, five patients became spontaneous pregnant. Two patients became pregnant with in vitro fertilization (IVF), and other two patients became pregnant with intrauterine insemination (IUI). Factors influenced pregnancy assessed a shorter duration of infertility. After the treatment, survey of satisfaction in Korean medical treatment in infertility was done. Out of thirty-two patients, convenience and reliability of Korean medical treatment was reported by who had an experience of sterilization surgery. After the assessment, seven patients who had an experience of sterilization surgery and beame pregnant were having more convenience than twelve patients who were not pregnant despite sterilization surgery. Conclusions : This study suggests Korean medical treatment is useful for infertile women and men, in reverse proportion to shorter duration of infertility.

불임여성의 고독감 수준에 관한 연구 (The Study of Loneliness in Infertile Women)

  • 배경진;노승옥;김정아
    • 대한간호학회지
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    • 제29권6호
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    • pp.1379-1391
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    • 1999
  • The purpose of this study was to investigate loneliness in infertile women and determine how loneliness related to personal characteristics, cause of infertility, family composition, and family conflicts. It also provides basic data for nursing strategies concerning infertile women.A total of 182 subjects were selected at an infertile clinic in Seoul, Korea. Data were collected from May 2 to June 21, 1997 by questionaire. It consisted of questions concerning general characteristics, items relating to infertility, and the Loneliness Scale. The UCLA Loneliness scale was used(more specifically, the Korean version of the Revised UCLA Scale by Kim Ok Soo.) The data were analyzed by using SPSS/PC computer program. The result are as follows : 1. The mean age of infertile women was 32.4 years old, and the mean age of souses was 34.8 yerars old. 30.2% of women had a marital duration of 3-5 years, and 25.8% had a marital duration of 5-10 years. 23.1% reported the main etiology of infertility as unexplained, 18.1% reported ovulation disturbances, and 26.4% reported complex causes. 3.8% of the couples had sexual relationship difficulty 83% lived in nuclear families, while 17% lived in large families. 2. The mean loneliness scores of infertile women was 35.53(SD=8.66). The total loneliness score of this study was 80. 3. There were significant differences in loneliness scores according to ages(F=6.893, p=.001), education background(t=4.418, p=.000), and the educational background of husband(t=2.339, p=.020). 4. Loneliness scores related to family situations were significantly different according to several male nephews in husbands' family(F=2.822, p=.027). 5. Loneliness scores related to conflicts were significantly different according to husbands and their family(F=11.465, p=.000). Nurses should acknowlege the fact that some infertile women may experience loneliness. In conclusion, nurses can provide infertile women with information about ways to decrease loneliness and create support groups for themselves, assisting infertile women to adjust to the experience of infertility through positive methods.

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