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Diagnostic Potential of Strain Ratio Measurement and a 5 Point Scoring Method for Detection of Breast Cancer: Chinese Experience

  • Parajuly, Shyam Sundar;Lan, Peng Yu;Yun, Ma Bu;Gang, Yang Zhi;Hua, Zhuang
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.4
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    • pp.1447-1452
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    • 2012
  • Aim: To evaluate the differential diagnostic potential of lesion stiffness assessed by the sonoelastographic strain index ratio (SR) and elastographic color scoring system (UE) for breast lesions. Materials and Methods: Three hundred and forty two breast masses (158 benign and 184 malignant) from 325 consecutive patients (mean age 44.2 years; range 16-81)who had been scheduled for a sonographically guided core biopsy were examined proposed by Itoh et al, with scoring 1-3=benign and 4-5=malignant. Strain and area ratios of each lesion were calculated within the same machine. Histological diagnosis was used as the reference standard. The area under the curve (AUC) and cut-off point were obtained by receiver operating curve and the cross table Fischer Test was carried out for assessing diagnostic value. Sensitivity, specificity, PPV, NPV, accuracy and false-discovery rates were compared. Results: The mean strain ratios for benign and malignant lesions were 1.87 and 7.9 respectively. (P<0.0001). When a cutoff point of 3.54 was used, SR had a sensitivity of 94.6%, a specificity 94.3%, a PPV of 95.1%, an NPV of 93.7% and an accuracy of 94.4%. The AUC values were 0.90 for the 5 point scoring system (UE) and 0.96 for the strain index ratio. The overall diagnostic performance was SR method was better (P<0.05). Conclusions: Strain ratio measurement could be another effective predictor in elastography imaging besides 5 the point scoring system for differential diagnosis of breast lesions.

A Study on the Relation between Riverbed Structure and Pollutant Concentration in Downstream of Nakdong River (낙동강 하류의 하상구조와 오염물질과의 상관관계 연구)

  • 황선출;정성욱
    • Journal of Environmental Science International
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    • v.5 no.4
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    • pp.481-494
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    • 1996
  • This study was performed to investigate the relationship between concentrations of heavy metals in sediment and the depths of 27 sampling sites along the West Nakdong river in downstream of Nakdong River. The deepest site was Kangdong bridge nearby 20ft. From here, the depth was shallowed to Chidong gradually. In each site the smaller mesh was, the liger concentration of heavy metal becomed. Concentration of Zn, Cd, Cr and Cu at inflow point of Shinoe stream was 576.016 ppm, 262.307 ppm, 68.674 ppm and 61.634 ppm, respectively, the concentration was the higest at this point. From here, it was lowered gradually. The concentration of heavy metal at inflow point of Joman river was 155.328 ppm, 56.485 ppm, 25.200 ppm and 31.172 ppm, respectively, those concentrations were liger than other points with the exception of Shinoe stream. Therefore, woman river and Shinoe stream were the major source of pollution in West Nakdong river. Among two sources Shinoe stream was more important source of pollution. West Nakdong river has become lake by Noksan floodgate because it's pollution has had influence on Bonglim.

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A Study on recent tendency of anti-tumor herbal acupuncture (항암약침의 최신경향에 대한 고찰)

  • Lee, Yong-Yeon;Cho, Jung-Hyo;Lee, Yeon-Weol;Son, Chang-Gue;Cho, Chong-Kwan;Hwang, Kyu-Jeong;Yoo, Hwa-Seung
    • Journal of Pharmacopuncture
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    • v.4 no.3
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    • pp.23-37
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    • 2001
  • Objective: The purpose of this study is to develop and activate anti-tumor herbal acupuncture for cancer patients in South Korea. Methods: We investigated some literatures on anti-tumor herbal acupuncture which is used in South Korea and China, and made diagrams. Results: The results are summarized as follows. Anti-tumor herbal acupuncture is one of the traditional oriental medical method which is effective for cancer patients. In domestic studies, most of herb materials are belong to action of cooling&detoxification(25.0%) and strengthening body resistance(46.4%) which are proved to have effects of anti-tumor, immune activation and preventing tumor. In China, point injection therapy are used for improving symptoms of cancer patients and hea1ing tumor. Also herbal intravenous injection is used for combination of chinese traditional and western cancer therapy and treating cancer patients variously. Conclusions: From the above results. it is expected that anti-tumor herbal acupuncture is useful to improve clinical symptoms and quality of life(QOL) of cancer patients. Also we must develop new progressive methods of point injection and herbal intravenous injection for treating cancer patients, and advance clinical studies and trials.

Development of the Kinematic Global Positioning System Precise Point Positioning Method Using 3-Pass Filter

  • Choi, Byung-Kyu;Roh, Kyoung-Min;Cho, Sung-Ki;Park, Jong-Uk;Park, Pil-Ho;Lee, Sang-Jeong
    • Journal of Astronomy and Space Sciences
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    • v.29 no.3
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    • pp.269-274
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    • 2012
  • Kinematic global positioning system precise point positioning (GPS PPP) technology is widely used to the several area such as monitoring of crustal movement and precise orbit determination (POD) using the dual-frequency GPS observations. In this study we developed a kinematic PPP technology and applied 3-pass (forward/backward/forward) filter for the stabilization of the initial state of the parameters to be estimated. For verification of results, we obtained GPS data sets from six international GPS reference stations (ALGO, AMC2, BJFS, GRAZ, IENG and TSKB) and processed in daily basis by using the developed software. As a result, the mean position errors by kinematic PPP showed 0.51 cm in the east-west direction, 0.31 cm in the north-south direction and 1.02 cm in the up-down direction. The root mean square values produced from them were 1.59 cm for the east-west component, 1.26 cm for the south-west component and 2.95 cm for the up-down component.

Tumor-reducing effect of SB injection in a non-small cell lung cancer patient: A case report (비소세포폐암 환자의 종양 축소에 대한 SB 주사 효과 증례)

  • Park, Ji Hye;Park, So Jung;Kang, Hwi Joong;Cho, Chong Kwan;Han, Kyun In;Yoo, Hwa Seung
    • Journal of Korean Traditional Oncology
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    • v.19 no.1
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    • pp.61-68
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    • 2014
  • Objectives : To study the effect of SB injection on tumor size in an advanced non-small cell lung cancer patient. Methods : A patient was clinically diagnosed as advanced non-small cell lung cancer (Stage IIIa). Four cycles of intravenous SB injection were conducted. Each cycle lasted 4 days. The content of 7vials SB was injected every day. To compare the tumor size before treatment and after four cycles of SB injection, chest computed tomography (CT) was performed. Results : Follow-up CT images showed that the tumor size was reduced. In admission, size of the tumor $6.7{\times}8.5{\times}9.5cm$ on the left lower lobe of lung. After SB injection, size of the tumor $5.6{\times}6.8{\times}8.4cm$ by Chest CT. The patient's symptoms such as cough, sputum were improving until four cycles of SB injection. Numerical rating scale (NRS) showed improvement of Chest pain from point 3 to point 0. Conclusions : This case study suggests that intravenous SB injection may have significant effects of anti-tumor for non-small cell lung cancer.

ASSESSMENT AND CONTROL OF TOTAL NUTRIENT LOADS IN WATERSHED AND STREAM NETWORK IN SOUTH-WEST TEXAS

  • Lee, Ju-Young;Choi, Jae-Young
    • Water Engineering Research
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    • v.7 no.1
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    • pp.1-8
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    • 2006
  • Recently, the population growth and agricultural development are rapidly undergoing in the South-West Texas. The junction of three river basins such as Lavaca river basin, Colorado-Lavaca Coastal basin and Lavaca-Guadalupe Coastal basin, are interesting for non-point and point source pollutant modeling: Especially, the 2 basins are an intensively agricultural region (Colorado-Lavaca Coastal/Lavaca-Guadalupe Coastal basins) and several cities are rapidly extended. In case of the Lavaca river basin, there are many range land. Several habitat types wide-spread over three relatively larger basins and five wastewater discharge regions are located in there. There are different hazardous substances which have been released. Total nutrient loads are composed of land surface load and river load as Non-point source and discharge from wastewater facilities as point source. In 3 basins region, where point and non-point sources of poll Jtion may be a big concern, because increasing fertilizers and pesticides use and population cause. This project objective seeks to how to assess and control the accumulation of non-point and point source and discuss the main impacts of agriculture and environmental concern as non-point source with water quality related to pesticides, fertilizer, and nutrients and as point source with wasterwater discharge from cities. The GIS technique has been developed to aid in the point and non-point source analysis of impacts to natural resource within watershed. This project shows the losses in $kg/km^2/year$ of BOD (Biological Oxygen Demand), TN (Total Nitrogen) and TP (Total Phosphorus) in the runoff from the surface of 3 basins. In the next paper, sediment contamination will show how to evaluate in Estuarine habitats of these downstream.

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Effect of the Auriculoelectrostimulator on Blood Pressure In Hypertensive Rat Models (고혈압모델에서 귀혈위자극기의 혈압강하 효과)

  • Kim Hee-Young;Kim Sung-Ok;Hwang Hye-Jeong;Hahm Dae-Hyun;Lee Kwon-Soon;Kim Soon-Taek;Shim Insop;Lee Hye-Jung
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.3
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    • pp.724-728
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    • 2004
  • Several studies have shown that a low frequency stimulation can depress blood pressure in hypertension. We had developed a new auriculoelectrostimulator as an electronic blood pressure regulator for simple and easy stimulation. The new auriculoelectrostimulator was employed in hypertensive rat model induced by immobilization stress, diabetic and essential hypertensive rat models. Rats were stimulated by auriculoelectrostimulator at ear acupoint (Ear point for hypertension) bilaterally. Ear stimulation by auriculoelectrostimulator significantly decreased blood pressure in all hypertensive rat models and inhibited the increase of heart rates in stressed and spontaneous hypertensive rats. The results showed that auriculoelectrostimulator had depressive effects on hypertension in rat hypertensive models, suggesting that it is useful in treatment of hypertension.

The Critical Point Equation on 3-dimensional α-cosymplectic Manifolds

  • Blaga, Adara M.;Dey, Chiranjib
    • Kyungpook Mathematical Journal
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    • v.60 no.1
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    • pp.177-183
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    • 2020
  • The object of the present paper is to study the critical point equation (CPE) on 3-dimensional α-cosymplectic manifolds. We prove that if a 3-dimensional connected α-cosymplectic manifold satisfies the Miao-Tam critical point equation, then the manifold is of constant sectional curvature -α2, provided Dλ ≠ (ξλ)ξ. We also give several interesting corollaries of the main result.