• Advances in Traditional Medicine
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• 제8권4호
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• pp.386-394
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• 2008

The tissue extract (TTE) of a marine snail Telescopium telescopium, collected from the coastal regions of West Bengal, India, was extensively screened for pharmacological and biochemical properties. Telescopium telescopium (TTE) produced significant lysis of washed rat erythrocytes (both direct and indirect), produced haemorrhagic lesions in the skin and also released haemoglobin (in vitro tissue damage) from different tissue samples. TTE was found to produce pro-inflammatory effects when injected into the rat hind paw and also increased peritoneal vascular permeability. Furthermore, intravenous administration of TTE produced a decrease in blood pressure (hypotensive effect) in anaesthetized rats. The extract produced potent esterase activity, as was evident from the breakdown of FDA with subsequent release of fluorescein (in vitro). TTE also demonstrated prominent cholinesterase, phospholipase, phosphatase and protease activities.

• Asian Pacific Journal of Cancer Prevention
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• 제13권8호
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• pp.4057-4062
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• 2012

Objective: To study the level of awareness and knowledge about cancers and associated risk factors among households in selected states of India. Methods: In the study 3070 households were interviewed from six states viz, West Bengal, Kerala, Madhya Pradesh, Rajasthan and Mizoram. Results: Knowledge of cancers other than those related to tobacco was very low (prostate 8%, colon 11% ) among the communities, with a poor awareness of warning signs and symptoms. The knowledge varied from state to state. It is found that the major source of information related to cancers was television (38%) followed by friends and relatives (36%). Only about 15 % of respondents had knowledge about cancer awareness camps organized in their districts but they did not have knowledge about the organizers of the camp. Findings suggested a strong need for strengthening of DCCP. Conclusion: It is important to create awareness among community through educational programs on cancer prevention, preventable cancer risk factors, benefits of early diagnosis, and availability of screening facilities. Integration of District Cancer Control activities with NRHM could be the most cost-effective strategy to prevent cancers and rural population.

• Asian Journal for Public Opinion Research
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• 제5권3호
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• pp.204-227
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• 2018

This paper seeks to interrogate the very assumption of "sociality" in social media at a conceptual level and substantiate it with the help of information collected on aged people's use of conventional media $vis-{\grave{a}}-vis$ so called "social media" from the field work. Although global literature has written the obituary of mass media and promoted the "sociality" of social media, one needs to critically engage with such statement. Such statements have been an outcome of the established status of the "post broadcast" model of media where conventional media is in existence for some time and accessible to everyone in society. Further, this paper seeks to explore the interplay of new media in the life of the aged population in select areas of Kolkata city in the state of West Bengal, India. There are few studies on the ageing population's use of new media in the Indian context. While many of the studies reveal the new media literacy among the youth, this is unimportant as both the new media and the youth are relatively young as a field of research in media studies in India. What is missed in the earlier studies is, how new media plays an important function in the life of the aged population. How do older adults engage with the skilling and deskilling process of media literacy in their everyday life? And finally, do new media provide an extension to their on-going social relations? With the help of substantive details, the present study addresses the aforementioned queries.

• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.5049-5054
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• 2013

Background: To assess the treatment pattern and expenditure incurred by cancer patients undergoing treatment at government tertiary hospitals in India. Materials and Methods: A cross-sectional study of 508 cancer patients randomly selected from tertiary cancer hospitals funded by central/state governments located in major cities of five states in India, namely Kerala, Maharashtra, Rajasthan, West Bengal and Mizoram, during March - May 2011 was conducted. Information related to direct costs, indirect costs and opportunity costs incurred on investigations and treatment, major source of payment and difficulties faced by patients during the course of treatment was collected. Results: About 45% of the patients used private health facilities as the first point of contact for cancer related diseases as against 32% in public hospitals. About 47% sought private health facilities for cancer investigations, 21% at district/sub-district hospitals, and about 4% contacted primary health care facilities. A majority of the patients (76%) faced financial problems while undergoing treatment. Conclusions: The results highlight the importance of involving the primary health care system in the cancer prevention activities.

• Natural Product Sciences
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• 제11권2호
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• pp.109-114
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• 2005

Leucas aspera Link. (Lamiaceae) is an important medicinal plant in indigenous systems of medicine in India and commonly known as 'Thumbai'. It has various ethnomedicinal values as various traditional communities find diverse medicinal properties. It is used as antipyretic, stimulant, expectorant and diaphoretic drug. The present communication deals with the detailed pharmacognostical evaluation of whole plant of L. aspera collected from five different geographical zones of the country-Uttar Pradesh, Orissa, Karnataka, West Bengal and Gujarat. The botanical characters and TLC fingerprint profile of all the samples were quite similar but some variations were observed in physicochemical parameters. However, some microscopical characters and TLC profile can be used as diagnostic characters for identification of L. aspera, for example amphistomachic leaves and two types of trichomes-abundant, non glandular, uniseriate, 1-3 celled and few glandular, 2-5 celled stalk with rounded tip. Presence of some components at $R_fs-0.56$, 0.65 and 0.76 under UV 366 and at $R_fs-0.31$, 0.43, 0.60, 0.76 and 0.82 under visible light after derivetization in TLC profile may also be used as diagnostic character.

• International Journal of Knowledge Content Development & Technology
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• 제10권3호
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• pp.51-68
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• 2020

The library provides its services to satisfy the user's approach. Naturally, the development of library services may determine by considering the satisfaction of users. It traces users' perceptions regarding subject access highlighting problems in the retrieval of Bengali documents by subject. This study has designed to assess users' attitudes towards the retrievals of Bengali documents in OPAC through subject headings. For a collection of data, a representative sample has drawn from a large and heterogeneous population consisting of users in university libraries of West Bengal using a stratified sampling technique. Subsequently, under each of the universities, users' community was stratified into students, research scholars, and faculty members. Under each stratum, the sample selected on a random basis. The users met personally to collect relevant data, while they came to the library and went on to search OPAC. A structured schedule, prepared for the purpose, was presented before library users and consequently, interviews and interpretations recorded systematically. In this manner, several factors have identified concerning subject searching and retrieval performance for Bengali documents. This study explores the access using subject headings in multilingual information retrieval systems. Moreover, the suitability of subject headings for retrieval of Bengali resources has ascertained from the users' point of view. The findings demand standard principles and rules for the construction of Bengali subject headings to maintain uniformity and consistency.

• Molecules and Cells
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• 제38권1호
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• pp.51-57
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• 2015

The Caenorhabditis elegans peroxidasins, PXN-1 and PXN-2, are extracellular peroxidases; pxn-2 is involved in muscle-epidermal attachment during embryonic morphogenesis and in specific axon guidance. Here we investigate potential roles of the other homologue of peroxidasin, pxn-1, in C. elegans. A pxn-1 deletion mutant showed high lethality under heat-stress conditions. Using a transcriptional GFP reporter, pxn-1 expression was observed in various tissues including neurons, muscles, and hypodermis. A translational fusion showed that PXN-1::GFP was secreted and localized in extracellular matrix, particularly along body wall muscles and pharyngeal muscles. Various neuronal developmental defects were observed in pxn-1 mutants and in pxn-1 over-expressing animals, including handedness, branching, breakage, tangling, and defasciculation. These results suggest that pxn-1, like other peroxidasins, plays an important role throughout development.

• 한국지형학회지
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• 제24권3호
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• pp.133-147
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• 2017

This study investigated the cases of relative location, especially focused on the geomorphological situation, for the conceptualization of the location knowledge. In order to perform this study, first of all, I approached meaning of location. In this study I used the terms 'site' and 'situation'. 'Site' as used here means the location of a given place with its local internal features or resources. 'Situation' refers to the location of place as related to other places. As to location, no place exists in isolation. Therefore, it is necessary to look beyond the internal nature of the area itself to perceive its external relations with other areas. The examples of geomorphological situation were focused on the scale linkage of the examples, the interaction between elements of earth surface processes, and the method of comparative region. The regions of examples were the landscape of Mt. Hymalaya to Bengal deep sea fan, the climatical difference of continental east and west, the landscape of Mt. Geum & Sangju beach, the landscape of the south and north face of Mt. Mai., Hamjibaakgol asymmetrical valley, and the landscape of inland sea and outer sea type island.

• Parasites, Hosts and Diseases
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• 제59권4호
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• pp.409-413
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• 2021

In this study, we have collected and screened a total of 268 stool samples from diarrheal patients admitted to an Infectious disease hospital in Kolkata for the presence of Cryptosporidium spp. The initial diagnosis was carried out by microscopy followed by genus specific polymerase chain reaction assays based on 70 kDa heat shock proteins (HSP70). DNA sequencing of the amplified locus has been employed for determination of genetic diversity of the local isolates. Out of 268 collected samples, 12 (4.48%) were positive for Cryptosporidium spp. Sequences analysis of 70 kDa heat shock proteins locus in 12 Cryptosporidium local isolates revealed that 2.24% and 1.86% of samples were showing 99% to 100% identity with C. parvum and C. hominis. Along with the other 2 major species one recently described globally distributed pathogenic species Cryptosporidium viatorum has been identified. The HSP70 locus sequence of the isolate showed 100% similarity with a previously described isolate of C. viatorum (Accession No. JX978274.1, JX978273.1, and JN846706.1) present in GenBank.

• 한국동물생명공학회지
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• 제38권2호
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• pp.54-61
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• 2023

Background: Germ cells undergo towards male or female pathways to produce spermatozoa or oocyte respectively which is essential for sexual reproduction. Mesenchymal stem cells (MSCs) have the potential of trans-differentiation to the multiple cell lineages. Methods: Herein, rat MSCs were isolated from bone marrow and characterized by their morphological features, expression of MSC surface markers, and in vitro differentiation capability. Results: Thereafter, we induced these cells only by retinoic acid supplementation in MSC medium and, could able to show that bone marrow derived MSCs are capable to trans-differentiate into male germ cell-like cells in vitro. We characterized these cells by morphological changes, the expressions of germ cell specific markers by immunophenotyping and molecular biology tools. Further, we quantified these differentiated cells. Conclusions: This study suggests that only Retinoic acid in culture medium could induce bone marrow MSCs to differentiate germ cell-like cells in vitro. This basic method of germ cell generation might be helpful in the prospective applications of this technology.