• Journal of Advanced Marine Engineering and Technology
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• v.22 no.4
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• pp.560-568
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• 1998

Recently to develop an automobile with better properities many researches and investments have been executed. In this paper we intend to improve the automobile properties by reducing the weight of the engine without changing the dynamic characteristics. At first the vibration analysis by the Substructure Synthesis Mehtod and the exciting test of the engine model performed to confirm the reliability of the analyzing tools. And the weight minimiza-tion is performed by the Sensitivity Analysis and the Optimum Structural Modificationl. To decrease the engine weight ideally the weight of the parts with the low sensitivity is to cut mainly and the changing quantity of the natural frequency by the cut is to be recovered by the weight modification of the parts with the high sensitivity. As actually the mathematical unique solution for the homogeneous problem(i. e. 0 object func-tion problem)does not exist we redesign the engine block with much thinner initial thickness and recover the natural frequencies and natural modes of original structure by the sensitivity analy-sis and then observe the Frequency Response Function(FRF) for the interesting points. In this analysis the original thickness of the engine model is 8mm and the redesigned initial thicknesses are 5mm and 6mm, And the number of the interesting natural frequencies are 1, 2, 3, 4 and 5 respectively.

• Archives of Obesity and Metabolism
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• v.2 no.2
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• pp.54-63
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• 2023

Estrogen is crucial in regulating food intake, energy expenditure, glucose metabolism, and lipid metabolism. During menopause, the decline in estrogen levels predisposes women to weight gain, abdominal obesity, insulin resistance, type 2 diabetes, hypertension, and cardiovascular disease (CVD). Menopausal hormone therapy (MHT) prevents weight gain, improves lipid metabolism by lowering low-density lipoprotein cholesterol while raising high-density lipoprotein cholesterol, and delays the onset of type 2 diabetes in menopausal women. The effect of MHT on CVD in menopausal women remains controversial. The Women's Health Initiative study was terminated prematurely after it revealed that hormone administration increased the risk of myocardial infarction, stroke, and thromboembolism. However, some studies have found that MHT had no effect or decreased the risk of CVD. The inconsistent results were likely due to multiple factors, including the timing of hormone therapy initiation, duration of therapy, type and dosage, and presence or absence of CVD risk factors at the start of treatment. Despite its benefits in terms of managing weight gain and reducing the risk of type 2 diabetes, dyslipidemia, and CVD associated with obesity, it is not recommended as the primary therapy for weight loss or diabetes prevention. MHT is primarily indicated for postmenopausal women, who are likely to benefit from its potential to prevent weight gain and improve lipid metabolism.

• Asian-Australasian Journal of Animal Sciences
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• v.14 no.1
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• pp.77-81
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• 2001

The effects of dietary protein and lysine levels on lactating multiparous sows and litter performance were studied. Sixty-two crossbred multiparous sows ($Landrace{\times}Yorkshire$) were used. Thirty-three and twenty-nine sows were studied in their second parity and third parity respectively. The three dietary treatments were: (1) the control diet containing 15% CP and 0.75% lysine, (2) a diet containing 13% CP and 0.75% lysine (0.60% natural+0.15% synthetic), and (3) a diet containing 13% CP and 0.60% lysine. They were fed twice daily and allowed ad libitum access to food and water throughout a 28 day lactation from parturition until weaning. The results of this experiment showed that body weight and backfat losses of the sows from farrowing to weaning were significantly affected (p<0.01) by reducing dietary protein. Neither average daily feed intake nor weaning to estrus interval of sows were significantly different among treatments. Supplementing lower dietary protein with synthetic lysine could mitigate backfat losses, but could not prevent body weight losses in lactating multiparous sows. A corn-soybean meal diet containing 13% crude protein and 0.60% lysine did not significantly affect litter size and survival rate of weanling piglets compared with the 15% crude protein diet. There was a tendency towards decreased piglet weight at weaning (p<0.10) and reduced daily gain of piglets (p<0.11) when the multiparous sows were fed the 13% protein diet during lactation. We found a severe loss of body weight and backfat when reducing dietary protein for lactating multiparous sows.

• Fire Science and Engineering
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• v.30 no.6
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• pp.1-8
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• 2016

In cars, the amount of combustibles, such as plastics, textiles, etc., have increased dramatically to improve the fuel efficiency of cars by reducing the gross vehicle weight according to the increases in an oil price and to reduce environmental problems. One or two cars were involved in a parking lot fire prior to the mid-2000 s. On the other hand, there were many parking lot fires where the entire car was destroyed due to increasing the use of plastics. In this study, the quantity of combustibles in a car was 316.2 kg over a total weight 1935 kg. This is 16.34% of total weight and 10 times greater than that three decades earlier. When a sprinkler is installed as a parking lot fire protection system as a substitute for water spray, the water discharge of the sprinkler must maintain the original density of water spray, $20lpm/m^2$. In addition, the use of a hose reel $CO_2$ system at pilotis parking lots must be prohibited because the hose reel $CO_2$ system has no adaptability for a car fire. Instead, this study proposes foam, dry powder, loaded stream systems be used in parking lot fire suppression systems.

• Journal of Institute of Control, Robotics and Systems
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• v.17 no.10
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• pp.1021-1028
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• 2011

The objective of this paper is to optimize the design parameters of a novel mechanism for a robotic knee orthosis. The feature of the proposed knee othosis is to drive a knee joint with independent actuation during swing and stance phases, which can allow an actuator with fast rotation to control swing motions and an actuator with high torque to control stance motions, respectively. The quadriceps device operates in five-bar links with 2-DOF motions during swing phase and is changed to six-bar links during stance phase by the contact motion to the patella device. The hamstring device operates in a slider-crank mechanism for entire gait cycle. The suggested kinematic model will allow a robotic knee orthosis to use compact and light actuators with full support during walking. However, the proposed orthosis must use additional linkages than a simple four-bar mechanism. To maximize the benefit of reducing the actuators power by using the developed kinematic design, it is necessary to minimize total weight of the device, while keeping necessary actuator performances of torques and angular velocities for support. In this paper, we use a SGA (Simple Genetic Algorithm) to minimize sum of total link lengths and motor power by reducing the weight of the novel knee orthosis. To find feasible parameters, kinematic constraints of the hamstring and quadriceps mechanisms have been applied to the algorithm. The proposed optimization scheme could reduce sum of total link lengths to half of the initial value. The proposed optimization scheme can be applied to reduce total weight of general multi-linkages while keeping necessary actuator specifications.

• Journal of Physiology & Pathology in Korean Medicine
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• v.37 no.2
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• pp.25-29
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• 2023

This study was designed to establish an atopic dermatitis (AD) model using MC903 and was conducted to find out the optimal challenge concentration that can cause dermatitis symptoms enough to be experimentally verified while reducing adverse effects such as weight loss. MC903 was treated at concentrations of 2, 3, and 4 nmol/day, and evaluation of skin surface symptoms, water contents, histopathological changes, body weight changes, and spleen/body weight ratio was conducted. In addition, the expression level of thymic stromal lymphopoietin (TSLP) was also observed. In our results, MC903 induced AD skin lesions such as erythema, scab and fissure and lowered skin moisture level significantly. In addition, water holding capacities in the 3 or 4 nmol groups were diminished significantly compared to that in the control group. On the other hand, 4 nmol treatment induced a weight loss of up to 20% compared to control group. Finally, a higher level of TSLP expression was observed in the 3 nmol group than in the 2 nmol group or the 4 nmol group. Taken together, we propose a total 14-day protocol consisting of 3 days of sensitization (2 nmol/day) and 6 days of challenge (3 nmol/day).

• Journal of Korean Academy of Nursing
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• v.30 no.2
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• pp.391-401
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• 2000

This descriptive study was designed to identify the factors associated with weight control behaviors among 273 high school girls with normal body weight. The objectives of the study were ⅰ) to evaluate subjective obesity and satisfaction with the body shape, ⅱ) to describe the weight control behaviors and the motivation, ⅲ) to reveal the relationships between the weight control behaviors and BMI (Body Mass Index), iv) to investigate the relationships between the weight control behaviors and subjective obesity and satisfaction with the body shape, and v) to investigate the relationships between the weight control behaviors and family support. The results showed that 62.6% of the adolescent girls with normal weight perceived that they were fatty and 9.9% thought they were obese. Seventy-five percent of them were not satisfied with their body shape. Eighty percent of the participants reported the main motivation of weight control was to have an attractive appearance. In this study, self-reported weight control methods included dieting (64.8%, skipping or reducing meals), exercise (36.6%), and special dieting (20.1%) such as eating an increased amount of juice or vegetables. It was shown that the subjects who were not satisfied with their body shape and perceived themselves as fatty or obese were active in exercise, diet, and other special diets. Subjects who were on diets and special diets had a higher level of BMI than who were not on diet and special diet. Subjects who exercise had a lower level of BMI than who did not exercised. Family support was significantly related to exercise behavior. The research suggested that there is a increasing responsibility for school nurse to instruct on the body shape and weight control behaviors through health education and consultation. Also, the results suggested that it is important to develop proper diet and exercise methods for adolescents girls to maintain their weight and health.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2008.11a
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• pp.325-326
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• 2008

• Journal of Nutrition and Health
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• v.29 no.8
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• pp.874-880
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• 1996

The effects of an anabolic steroid, nandrolone phenylpropionate(NPP), on body weight gain and body protein, and muscle protein metabolism were inestigated in adrenocorticotrophic hormone(ACTH)-treated male and female rats. Daily injections of 100ug/day of ACTH for 7-8 days caused a cessation of growth in females and a net loss of body weight in males which were associated with significant reductions in body protein content. However, food intake was not affected by ACTH in either sex. The weight, protein content and fractional rate of protein synthesis, measured in vivo, of gastrocnemius muscle were all significantly reduced in both sexes. NPP at a dose of 4mg/kg body weight prevented the reduction in body weight gain in ACTH-treate females but not in males. However, boy protein content was increased by NPP in both sexes which was associated with increases in the weight, protein content and fractional rate of protein synthesis of gastrocnemius muscle. ACTH treatment caused a marked increase in plasma concentrations of corticosterone in both sexes. NPP suppressed much of the increases in corticosterone concentrations in both sexes. The results of the present study suggest that NPP exerts at least part of its anabolic effect by reducing plasma concentrations of catabolic glucocorticoid hormones, through suppressing the response of the adrenals to ACTH.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.18 no.2
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• pp.102-107
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• 2019

The vehicle market has developed environment-friendly vehicles to comply with fuel economy regulations and exhaust regulations that have become stricter and stricter over time. Many studies have been conducted to improve the travel performance and fuel economy of environment-friendly vehicles, and vehicle manufacturers have been studying how to manufacture light-weight vehicles in order to improve the fuel economy of both existing vehicles and the newer environment-friendly vehicles. Exemplary light-weight vehicle technologies optimizes the design of the vehicle body structure, which is a vehicle weight-reducing method that modifies component shapes or layouts to optimize the structure of the vehicle. In addition, the new process technology uses new light-weight and very strong materials, and not typical materials, to manufacture light-weight vehicles. This study aims at the optimal design of vehicle body structures using multi-materials for the Fender-Apron, which is an important frame member for the external front side of a vehicle body, by conducting FEA (Finite Element Analysis) and multi-material bonding.