• Clinical and Experimental Pediatrics
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• v.58 no.6
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• pp.224-229
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• 2015

Purpose: Thyroid dysfunction is common in preterm infants. Congenital hypothyroidism causes neurodevelopmental impairment, which is preventable if properly treated. This study was conducted to describe the characteristics of thyroid dysfunction in very low birth weight infants (VLBWIs), evaluate risk factors of hypothyroidism, and suggest the reassessment of thyroid function with an initially normal thyroid-stimulating hormone (TSH) as part of a newborn screening test. Methods: VLBWIs (January 2010 to December 2012) were divided into two groups according to dysfunction-specific thyroid hormone replacement therapy, and associated factors were evaluated. Results: Of VLBWIs, 246 survivors were enrolled. Only 12.2% (30/246) of enrolled subjects exhibited thyroid dysfunction requiring thyroid hormone replacement. Moreover, only one out of 30 subjects who required thyroid hormone treatment had abnormal thyroid function in the newborn screening test with measured TSH. Most of the subjects in the treatment group (22/30) exhibited delayed TSH elevation. Gestational age, Apgar score, antenatal steroids therapy, respiratory distress syndrome, patent ductus arteriosus, sepsis, intraventricular hemorrhage, postnatal steroids therapy, and duration of mechanical ventilation did not differ between the two groups. Birth weight was smaller and infants with small for gestational age were more frequent in the treatment group. Conclusion: Physicians should not rule out suggested hypothyroidism, even when thyroid function of a newborn screening test is normal. We suggest retesting TSH and free thyroxine in high risk preterm infants with an initially normal TSH level using a newborn screening test.

• Journal of the East Asian Society of Dietary Life
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• v.16 no.3
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• pp.281-291
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• 2006

This study investigated the effect of the powder of the small water dropwort(PSWD) and brewer's yeast(BY) on the liver function and serum lipid metabolism in alcohol-consuming rats. Male Sprague-Dawley rats were fed an AIN-93 diet(control), ethanol plus control(A), ethanol plus PSWD(AS), ethanol plus BY(AB), ethanol plus PSWD and BY(ABS) diet for seven weeks. The feed intake, body weight gain and feed efficiency ratio were the lowest and in the alcohol-consuming groups. The weight of the liver, kidney, spleen and epididymis of the anatomized rats showed positive correlation with the body weight gain. Compared with group A, the content of the lipid in the serum was significantly low in the AS and AB groups. In particular, it was the most effective in the AB group. The GOT, GPT and ALP level in the serum showed a significant difference in the alcohol-consuming groups. Compared with the A group, they showed a significantly low difference in the AS and AB groups. The total cholesterol and triglyceride levels in the liver were similar in all groups. The weight of the feces was significantly different but there was no significant difference in the content of total cholesterol and triglyceride levels in the AS and AB groups. These results suggest that BY and PSWD improve the liver function, and had an effect on reducing the lipid content of the serum and feces of alcohol-consumed rats. In particular, the effect of BY which contained protein, dietary fiber and vitamin B was higher than that of PSWD.

• Journal of applied mathematics & informatics
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• v.5 no.3
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• pp.867-875
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• 1998

In this paper we prove that any continuous function on a bounded closed interval of can be approximated by the superposition of a bounded sigmoidal function with a fixed weight. In addition we show that any continuous function over $\mathbb{R}$ which vanishes at infinity can be approximated by the superposition f a bounded sigmoidal function with a weighted norm. Our proof is constructive.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 1998.10a
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• pp.157-162
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• 1998

Dynamic loads may arise from rotating parte of pump if they are insufficiently balanced. The magnitude of pump induced vibrations varies according to the weight, eccentricity, and unbalanced mass of pump. This is a study to estimate the pump induced vibration in time and frequency domain by transfer function. The transfer function has real and imaginary information of signals, and response function has also real and imaginary information. So the vibration force can be obtained from the response and transfer function by complex calculation. The amplitudes and components of 50Hp pump vibration force are suggested.

• Korean Journal of Community Nutrition
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• v.17 no.2
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• pp.243-257
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• 2012

The purpose of this study was to evaluate pancreatic ${\beta}$-cell function of Korean adult and to examine the associations between ${\beta}$-cell function and nutrient intakes. Data were analyzed for 1,917 male and 2,885 female subjects older than 30 years using 'The Forth Korean National Health and Nutrition Survey in 2009'. We calculated HOMA ${\beta}$-cell (The homeostasis model assessment of ${\beta}$-cell function) using fasting glucose and fasting insulin for assessing ${\beta}$-cell function. Subjects were divided into HHG (High HOMA ${\beta}$-cell Group) or LHG (Low HOMA ${\beta}$-cell Group) according to median of HOMA ${\beta}$-cell, and then nutrient intakes were compared between two groups. In the entire study population, HHG showed lower percent of carbohydrate intakes (p < 0.05), and higher fat (p < 0.01), percent of fat (p < 0.05), vitamin A (p < 0.05), carotene (p < 0.05) and riboflavin (p < 0.05) intakes than LHG. In addition, levels of HOMA ${\beta}$-cell were negatively correlated with percent of carbohydrate (${\beta}$ = -0.040, p < 0.05), and positively correlated with percent of fat (${\beta}$ = 0.046, p < 0.01). The subjects were then divided into two subgroups according to body mass index values, either $23kg/m^2$ (under- and normal-weight) or ${\geq}23kg/m^2$ (over-weight and obese). Significant differences of some nutrients intakes and correlations with HOMA ${\beta}$-cell were observed only in under- and normal weight subjects, but not in over-weight and obese subjects. In conclusion, high carbohydrate, lower fat and lower vitamin intakes may be related with pancreatic ${\beta}$-cell dysfunction in under- and normal-weight Korean.

• Proceedings of the KSME Conference
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• 2007.05a
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• pp.96-101
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• 2007

A new metallic sandwich panel with a quasi-Kagome truss core subjected to bending load has been analyzed. First, equations of the failure loads corresponding to the eight failure modes are presented. Then, non-dimensional forms of the equations are derived as functions of three geometric variables, one material parameter (yield strain), one load index and one weight index. Failure maps are presented for a given weight index. By using the dimensionless forms of equations as the design constraints, two kinds of optimization are performed. One is based on the weight, that is, the objective function, namely, the dimensionless load is to be maximized for a given weight. Another is based on the load, that is, the dimensionless weight is to be minimized for a given load. The results of the two optimization processes are found to agree each other. The optimized geometric variables are derived as a function of given weights or failure loads. The performance of the quasi-Kagome truss as the core of a sandwich panel is evaluated by comparison with those of honeycomb cored and octet truss cored panels

• Transactions of the Korean Society of Mechanical Engineers A
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• v.31 no.9
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• pp.943-950
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• 2007

A new metallic sandwich panel with a quasi-Kagome truss core subjected to bending load has been analyzed. First, equations of the failure loads corresponding to the eight failure modes are presented. Then, non-dimensional forms of the equations are derived as functions of three geometric variables, one material parameter (yield strain), one load index and one weight index. Failure maps are presented for a given weight index. By using the dimensionless forms of equations as the design constraints, two kinds of optimization are performed. One is based on the weight, that is, the objective function, namely, the dimensionless load is to be maximized for a given weight. Another is based on the load, that is, the dimensionless weight is to be minimized for a given load. The results of the two optimization processes are found to agree each other. The optimized geometric variables are derived as a function of given weights or failure loads. The performance of the quasi-Kagome truss as the core of a sandwich panel is evaluated by comparison with those of honeycomb cored and octet truss cored panels.

• Journal of Yeungnam Medical Science
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• v.21 no.2
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• pp.133-142
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• 2004

Chronic obstructive pulmonary disease(COPD) is characterized by a not entirely reversible limitation in the airflow. An airflow limitation is progressive and associated with an abnormal inflammatory response of the lung to gases and harmful particles. In COPD, the weight loss is commonly observed and there is a negative impact on the respiratory as well as skeletal muscle function. The pathophysiological mechanisms that result in weight loss in COPD are not fully understood. However, the mechanisms of weight loss in COPD may be the result of an increased energy expenditure unbalanced by an adequate dietary intake. The commonly occurring weight loss and muscle wasting in COPD patients adversely affect the respiratory and peripheral muscle function, the exercise capacity, the health status, and even the survival rates. Therefore, it is very valuable to include management strategies that the increase energy balance in order to increase the weight and fat free mass. A Better understanding of the molecular and cellular pathological mechanisms of COPD can improve the many new directions for both the basic and clinical investigations. The Nutritional supply is an important components of a multidisciplinary pulmonary rehabilitation program. Future studies combining an exercise program, the role of anabolic steroids, nutritional individualization, a more targeted nutritional therapy, and the development of new drugs including anti-cytokines is needed for the effective management of COPD.

• Tribology and Lubricants
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• v.39 no.3
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• pp.94-101
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• 2023

Automotive wheel bearings are a critical component of vehicles that support their weight and facilitate rotation. Life and stiffness are significant performance characteristics of wheel bearings. Designing wheel bearings involves finding optimal design variables that satisfy both performances. CO₂ emission reduction and fuel efficiency regulations attribute to the recent increase in design requirements for lightweight and compact automotive parts while maintaining performance. However, achieving a design that maintains performance while reducing weight poses challenges, as performance and weight are generally inversely proportional. In this study, we perform design optimization of automotive wheel bearings considering life and stiffness. We develop a program that calculates the basic rated life and modified rated life based on international standards for evaluating the life of wheel bearings. We develop a regression equation using regression analysis to address the time-consuming stiffness analysis during repetitive analysis. We perform ANOVA and main effect analyses to understand the statistical characteristics of the developed regression equation. Furthermore, we verify its reliability by comparing the predicted and test results. We perform design optimization using the developed life prediction program, stiffness regression equation and weight regression equation. We select bearing specifications and geometry as design variables, weight as the cost function, and life and stiffness as constraints. Through design optimization, we investigate the influence of design variables on the cost function and constraints by comparing the initial and optimal design values.

• Journal of the Korean Society of Physical Medicine
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• v.18 no.3
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• pp.31-37
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• 2023

PURPOSE: This study aimed to investigate the relationship between being underweight and respiratory function indicators such as pulmonary function, respiratory muscle strength, and diaphragm thickness in normal adults without lung disease. METHODS: The participants in this experiment were thirty young adults. To compare the respiratory function between the underweight and normal weight individuals, 15 participants were selected from each of the underweight and normal weight groups based on body mass index. Respiratory function tests were conducted through pulmonary function tests and respiratory muscle strength tests. Diaphragm thickness was measure with ultrasonography, and physical characteristics were obtained from grip strength and waist circumference. An independent t-test was used to compare the averages of the parameters measured in the two groups. RESULTS: In the respiratory function tests between the two groups, statistically significant differences (p < .05) emerged in the ratio of the predicted forced vital capacity (%FVC), the ratio of the predicted forced expiratory volume in one second (%FEV1), maximal expiratory pressure (MEP), and diaphragm thickness at the functional residual capacity (FRC). There was no statistically significant difference in the forced vital capacity, forced expiratory volume in one second, maximal inspiratory pressure, diaphragm thickness at the total lung capacity, and thickening ratio (p > .05). CONCLUSION: Decreases in some variables of respiratory function, such as the %FVC, %FEV1, MEP, and diaphragm thickness at the FRC were observed in underweight subjects. However, it is difficult to determine whether it affected the overall respiratory function. Future studies are needed to clearly identify the relationship between being underweight and respiratory function.