• Title/Summary/Keyword: Wee1B

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Effects of Hafnium, Boron and Zirconium on the Ductility of Ni$_3$(Al, Fe) Intermetallic Compounds

  • Lim, S.H.;No, J.Y.;No, K.S.;Wee, D.M.
    • Korean Journal of Materials Research
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    • v.2 no.4
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    • pp.306-310
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    • 1992
  • Effects of hafnium, boron and zirconium on the ductility of Ni$_3$(Al, Fe) intermetallic compounds were studied using tensile test and SIMS analysis. Ni$_3$(Al, Fe) alloy with 0.1 at.% Hf, 0.05 at.% B and 0.1 at.% Zr additions showed maximum elongations of about 30% at 300K, 10% at 300K and 14% at 473K, respectively. The fracture mode of the alloy without the additive was the mixture of intergranular and transgranular fractures, but the addition of Hf, Zr or B changed the fracture mode to transgranular only. SIMS analysis showed that the beneficial effects of Hf, Zr or B segregation on the grain boundary strength are consistent with the grain boundary cohesion theory.

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Design of Two-port MIMO Antennas without Space for Isolation

  • Jo, Hyun-Dong;Park, Wee-Sang
    • International journal of advanced smart convergence
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    • v.1 no.1
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    • pp.1-5
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    • 2012
  • We propose a structure for a multiple input multiple output antenna which has no space for isolation. The antenna operates in a frequency range of 2.4-2.48 GHz and can achieve a high channel capability as a Bluetooth antenna. The MIMO antenna consists of two planar inverted F antennas with symmetric structure. We designed the proposed antenna using HFSS simulator, and we designed the fabricated antenna using PCB fabricator. The MIMO antenna's isolation $S_{21}{\leq}-10dB$ and reflection coefficient $S_{11}{\leq}-20dB$. The proposed antenna's specification satisfies Bluetooth antenna's criteria and has more space than the existing MIMO antennas, which have space for isolation.

Oocyte Maturation Process of Zebrafish (Danio rerio), an Emerging Animal Model (새로운 실험 동물 모델인 제브라피쉬(Danio rerio)의 난자 성숙 기작)

  • Han, Seung Jin
    • Journal of Life Science
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    • v.25 no.10
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    • pp.1184-1195
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    • 2015
  • The zebrafish is an emerging vertebrate model organism in reproductive biology. The oocyte maturation of zebrafish is triggered by maturation inducing hormone (MIH, 17α,20β-Dihydroxy-4-pregnen-3-one). In almost all animals, the oocyte maturation is governed by activation of pre-MPF which consists of cyclinB and inactive Cdk1. In the oocyte of Xenopus and mice, the activity of Cdk1 is regulated in two ways, one is the interaction with cyclinB and the other is phosphorylation/dephosphorylation of T14/Y15 residues on the Cdk1 by Wee1 and Cdc25. Unlike Xenopus and mice that have a sufficient amount of pre-MPF, pre-MPF is absent in GV oocyte of most teleost including zebrafish. Therefore, the activation of MPF during zebrafish oocyte maturation might totally depend on de novo synthesis of cyclinB proteins. It is reported that the translation of maternal mRNA is regulated by combination of several RNA binding proteins such as CPEB, Dazl, Pum1/Pum2, and insulin-like growth factor2 mRNA-binding protein 3 in the zebrafish oocytes. However, the definitive mechanism of these proteins to regulate the translation of stored maternal mRNAs remains to be elucidated. Therefore, the investigation of the maturation process of the zebrafish oocyte will provide new information that can help identify the role of translational control in early vertebrate oocyte maturation.

The Sex Determination Mechanisms in Maize: Cell Death, Cell Protection and Cell Cycle Arrest (옥수수 성 결정 메커니즘: 세포 사멸, 세포 방어, 세포주기 멈춤)

  • Kim, Jong-Cheol;Lee, Kyun-Oh
    • Journal of Life Science
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    • v.16 no.4
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    • pp.699-703
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    • 2006
  • Maize (Zea mays L.) is a monoecious plant, which separates male (tassel) and female (ear) floret that evolved into increasing heterogeneity. In each floret, male or female, bears both one pistil and three stamens primodia before diverged to unisexual state. When diverged to tassel, pistil cell death occurs in the pistil primodium, which is mediated by TASSELSEED genes. In contrast, cell protection occurs in the ear pistil from TASSELSEED-mediated cell death, which is mediated by SILKLESS1 gene. On the other hand, cell cycle arrest occurred for a long time in the ear stamens and then the stamens eventually dye. The cell cycle regulating genes such as CYCLIN B and WEE1 are involved in this process. Furthermore, the temporal and spatial regulation of gibberellin biosynthesis may cause cell cycle block in arresting stamen cells. This review describes the cell death, cell protection, and cell cycle arrest mechanism during maize sex determination process at the molecular, cellular and developmental biology, and genetic levels.

WASHINGTON CCD PHOTOMETRY OF THE OLD OPEN CLUSTER TOMBAUGH 2

  • WEE SUN-OK;LEE MYUNG GYOON;GEISLER DOUG
    • Journal of The Korean Astronomical Society
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    • v.29 no.spc1
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    • pp.147-148
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    • 1996
  • We have estimated a metal abundance of [Fe/H]= -0.48 $\pm$ 0.14 dex, a reddening of E(B- V)= 0.30 mag, an age of 2.0 $\pm$ 0.4 Gyr, and a distance of 7.9 $\pm$ 0.8 kpc for Tombaugh 2 using the Washington filter system.

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DRG2 Regulates G2/M Progression via the Cyclin B1-Cdk1 Complex

  • Jang, Soo Hwa;Kim, Ah-Ram;Park, Neung-Hwa;Park, Jeong Woo;Han, In-Seob
    • Molecules and Cells
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    • v.39 no.9
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    • pp.699-704
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    • 2016
  • Developmentally regulated GTP-binding protein 2 (DRG2) plays an important role in cell growth. Here we explored the linkage between DRG2 and G2/M phase checkpoint function in cell cycle progression. We observed that knockdown of DRG2 in HeLa cells affected growth in a wound-healing assay, and tumorigenicity in nude mice xenografts. Flow cytometry assays and [$^3H$] incorporation assays indicated that G2/M phase arrest was responsible for the decreased proliferation of these cells. Knockdown of DRG2 elicited down-regulation of the major mitotic promoting factor, the cyclin B1/Cdk1 complex, but upregulation of the cell cycle arresting proteins, Wee1, Myt1, and p21. These findings identify a novel role of DRG2 in G2/M progression.

Photonic-Assisted Reactive-Near-Field Analysis of a 3 dB-Tapered Ka-Band Array Antenna

  • Lee, Dong-Joon;Kang, Jeong-Jin;Kang, No-Weon;Kim, Wan-Sik;Park, Wee-Sang;Rothwell, Edward J.;Whitaker, John F.
    • Journal of electromagnetic engineering and science
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    • v.10 no.1
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    • pp.18-24
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    • 2010
  • A Ka-band microstrip array antenna for wide-range detection of moving targets is analyzed through a photonicassisted reactive-near-field characterization technique. The antenna array employs a 3-dB-tapered feed network to suppress the sidelobe level while retaining a wide azimuth beamwidth for a wide detection range. The relative nearelectric field patterns of the array and its 3-dB-tapered feed lines have been measured using an electro-optic fieldmapping technique for minimally invasive millimeter-wave sensing. A number of typical limitations on the technique, involving bandwidth, low signal-modulation depth, and high laser-induced noise in high-frequency applications, have been overcome by suppressing the carrier portion of the optical interrogation beam.

Chunghyuldan Downregulates the Activation of Transcription Factors NF - kB and AP-1 of BV-2 Cells Induced by Lipopolysaccharide

  • WEE Sung-SooK;BAE Eun-Ah;PARK Jin-Sun;KIM Hee-Sun;CHo Hee Jae;Ryu Jong-Hoon;KIM Dong-Hyun
    • Biomolecules & Therapeutics
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    • v.13 no.4
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    • pp.214-219
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    • 2005
  • Chunghyuldan (Qingxuedan in Chinese) (CHD) has been used for patients with atherosclerosis and brain ischemia in Korea. To evaluate antiischemic activity of CHD, its antiinflammatory effect in lipopolysaccharide-induced BV-2 cells was investigated. CHD potently inhibited nitric oxide (NO) production in LPS-induced BV-2 cells with an $IC_{50}$ value of 4.8${\mu}g/ml$. CHD did not only inhibit mRNA and protein expression levels of inducible NO synthase and cyclooxygenase-2 in LPS-induced BV-2 cells, but also repressed mRNA expression levels of proinflammatory cytokines IL-l$\beta$ and TNF-$\alpha$. CHD also downregulated the activation of NF-kB and AP-l transcription factors induced by LPS. These results suggest that CHD may improve inflammatory brain ischemia by the downregulation the activation of NF-kB and AP-l transcription factors.

Optical Properties of $Bi_2S_3$ Thin films ($Bi_2S_3$ 薄膜의 光學的 特性)

  • Wee, Sung-Dong
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.26 no.4
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    • pp.62-66
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    • 1989
  • $Bi_2S_3$ polycrystalline and $Bi_2S_3$ amorphous thin tilm were grown by the evaporation method. The measured lattic parameters were $a=1.708{\AA},\;b=0.351{\AA},\;and\;C=3.943{\AA}$ at substrate temperature $210^{cric}C$ were shown to have the orthorhombic structure. The energy gape of $Bi_2S_3$ polycrystalline that was made from thin film were measured to be 1.375eV at $289^{cric}K.$ The optical band gap of $Bi_2S_3$ amorphous thin film was measured to be 1.71eV at $289^{cric}K.$ It was supposed to mechanism that a photon absorption was changed at the center of 674nm (1.84eV)

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Design and development of 1 kJ Md:Glass laser for the basic research of plasma (플라즈마 기반연구를 위한 1 kJ 급 Nd:Glass 레이저 구축)

  • Hong, S.K.;Lim, C.H.;Wee, S.B.
    • Proceedings of the KIEE Conference
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    • 2006.07c
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    • pp.1457-1458
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    • 2006
  • 좁은 공간에 고출력 고에너지 레이저를 집속할 때 발생하는 고밀도, 고에너지 플라즈마 연구는 상태방정식, 실험실 천체물리, 전자가속 둥 기초 분야 뿐 아니라 X-선 및 극자외선 광원 개발, 원전 유지보수 등 다양한 산업 활용 분야를 갖고 있어 최근 미국, 프랑스, 일본, 중국 등 선진강대국에서 크게 주목 받고 있는 연구 분야이다. 한국원자력연구소는 물리나 광학의 원천기술 뿐 아니라 미래 산업에 파급효과 큰 플라즈마 기반 연구를 위하여 1 kJ급 고에너지 Nd:Glass 레이저 시설을 구축하고 있다.

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