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Preliminary Study on Electron Paramagnetic Resonance(EPR) Signal Properties of Mobile Phone Components for Dose Estimation in Radiation Accident (방사선사고시 피폭선량평가를 위한 휴대전화 부품의 전자상자성공명(EPR) 특성에 대한 예비 연구)

  • Park, Byeong Ryong;Ha, Wi-Ho;Park, Sunhoo;Lee, Jin Kyeong;Lee, Seung-Sook
    • Journal of Radiation Protection and Research
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    • v.40 no.4
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    • pp.194-201
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    • 2015
  • We have investigated the EPR signal properties in 12 components of two mobile phones (LCD, OLED) using electron paramagnetic resonance (EPR) spectrometer in this study.EPR measurements were performed at normal atmospheric conditions using Bruker EXEXSYS-II E500 spectrometer with X-band bridge, and samples were irradiated by $^{137}Cs$ gamma-ray source. To identify the presence of radiation-induced signal (RIS), the EPR spectra of each sample were measured unirradiated and irradiated at 50 Gy. Then, dose-response curve and signal intensity variating by time after irradiation were measured. As a result, the signal intensity increased after irradiation in all samples except the USIM plastic and IC chip. Among the samples, cover glass(CG), lens, light guide plate(LGP) and diffusion sheet have shown fine linearity ($R^2$ > 0.99). Especially, the LGP had ideal characteristics for dosimetry because there were no signal in 0 Gy and high rate of increase in RIS. However, this sample showed weakness in fading. Signal intensity of LGP and Diffusion Sheet decreased by 50% within 72 hours after irradiation, while signals of Cover Glass and Lens were stably preserved during the short period of time. In order to apply rapidly EPR dosimetry using mobile phone components in large-scale radiation accidents, further studies on signal differences for same components of the different mobile phone, fading, pretreatment of samples and processing of background signal are needed. However, it will be possible to do dosimetry by dose-additive method or comparative method using unirradiated same product in small-scale accident.

Disease Reaction of a Japonica Rice, Keumo3, and Detection of a Linked DNA Marker to Leaf Blast Resistance ("금오3호"의 벼 잎도열병 저항성 특성 및 저항성 연관 마커 탐색)

  • Lee, Jong-Hee;Kwak, Do-Yeon;Pakr, Dong-Soo;Roh, Jae-Hwan;Kang, Jong-Rae;Kim, Choon-Song;Jeon, Myeong-Gi;Yeo, Un-Sang;Yi, Gihwan;Shin, Mun-Sik;Oh, Byeong-Geun;Hwang, Hung-Goo
    • Korean Journal of Breeding Science
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    • v.40 no.4
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    • pp.408-413
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    • 2008
  • Rice blast resistance is considered one of the most important traits in rice breeding and the disease, caused by Magnaporthe grisea Barr, has brought significant crop losses annually. Moreover, breakdown of resistance normally occurs in two to five years after cultivar release, thus a more durable resistance is needed for better control of this disease. We developed a new variety, Keumo3, which showed strong resistance to leaf blast. It was tested in 2003 to 2007 at fourteen blast nursery sites covering entire rice-growing regions of South Korea. It showed resistance reactions in 12 regions and moderate in 2 regions without showing susceptible reactions. Durability test by sequential planting method indicated that this variety had better resistance. Results showed that Keumo3 was incompatible against 19 blast isolates with the exception of KI101 by artificial inoculation. To understand the genetic control of blast resistance in rice cultivar Keumo3 and facilitate its utilization, recombinant inbred lines (RIL) consisting of 290 F5 lines derived from Akidagomachi/Keumo3 were analyzed and genotyped with Pizt InDel marker zt56591. The recombination value between the marker allele of zt56591 and bioassay data of blast nursery test was 1.1%. These results indicated that MAS can be applied in selecting breeding populations for blast resistance using zt56591 as DNA marker.

Establishment and Operation of the Local Government Archives: Recommendations (지방기록물관리기관 설립의 방향과 방법)

  • Ji, Su-gol
    • The Korean Journal of Archival Studies
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    • no.21
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    • pp.247-281
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    • 2009
  • Local governments in Korea, sixteen in total, shall establish local government archives to and manage preserve their permanent archives to comply with the Public Records Management Act amended in October 2006. National Archives of Korea(NAK) directed the local governments to recruit legally qualified archivists by the end 0f 2006 and to plan on the establishment and operation of the local government archives by the end 2007. However, none of the government archives was established by far. Government officials in NAK and the local governments raised the limits of the budget and human resources. What is more serious is that they don't concern why the archives are necessary and what missions and functions the archives should have. In this paper, I summarized the present situation and problems in establishing the local archives, and what we will do to establish normal government archives. First, local governments should establish "local government records commissions" and employ qualified archivists. The local government records commission should comprise concerned and qualified members. The records commission, as a policy and decision-making body, should make plans and implement the plans to establish the local archives, establish professional training programs to produce qualified archivists, promote local archives community activities, determine operational issues, and make a long-term development plan satisfying local demands. Second, the local government archives share existing repositories of NAK. Third, after the establishment of the archives, the local archives should perform normal records and archives management of the local governments as records acts mandate, do general records surveys and appraise the records created in the local governments. The local government archives should collect valuable local archives including private archives, and arrange and make usable them to provide access. They also promote and coordinate various cultural heritage community activities related to the local archives.

A Study on the Factors Affecting Health Promoting Lifestyles of Some Workers (일부 직업인의 건강증진생활양식에 영향을 미치는 요인 연구)

  • Lee Eun-Kyoung;An Byung-Sang;Yu Taek-Su;Kim Seoung-Cheon;Jeung Jea-Yeal;Park Young-Shin;Jahng Doo-Sub;Song Yung-Sun;Lee Ki-Nam
    • Journal of Society of Preventive Korean Medicine
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    • v.4 no.2
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    • pp.119-141
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    • 2000
  • The current industrial health service is shifting to health improvement business with 1st primary prevention-focused service from secondary and tertiary prevention-focused business, and Oriental medicine can provide such primary prevention-focused service due to the characteristics of its science. In particular, the advanced concept of health improvement can match the science of health care of Oriental medicine. Notably, what is most important in health improvement is our lifestyle, This does not underestimate the socio-environmental factors, which have lessened their importance due to modernism. The approach of Oriental medicine weighs more individuals' lifestyle and health care through self-cultivation. This matches the new model of advanced health business. Oriental medicine is less systemized than Western medicine, but it can provide ample contents that enhance health. If we conceive health-improvement program based on the advantages provided by these two medical systems, this will influence workers to the benefit of their health. Also, health Program needs to define factors that determine individual lives, and to provide information and technologies essential to our lives. The Oriental medicine approach puts more stress on a subject's capabilities than it does on the effect his surrounding environment can have. This needs to be supported theoretically by not only defining the relations between an individual's health state and his lifestyle, but also identifying the degree to which an individual in the industrial work place practices health improvement lifestyle . This is the first step toward initiating health-improvement business . In order to do this, this researcher conducted a survey by taking random samplings from workers, and can draw the following conclusions from it. 1 The sampled group is categorized into', by sender, female 6.6%, and male 93.4%, with males dominant; by marriage status , unmarried 43.9% and married 55.6%, with both similar percentage, and, by age, below 30, 48.4%, between 30 and 39, 27.4%, between 40 and 49, 18.2%, and over 50, 6.0%. The group further is categorized into; by education, middle school or under 1.7%, high school 30.5%, and junior college or higher 65.8% with high school and higher dominant: and by income, below 1.7 million won 24.2%, below 2.4 million won 14.8%, and above 2.4 million 6.3% Still, the group by job is categorized into collegians with 23.9%, office worker with 10.3%, and professionals with 65.8% , and this group does not include workers engaged in production that are needed for this research, but mostly office workers . 2. The subjects selected for this survey show their degree of practicing health-improvement lifestyle at an average of 2.63, health management pattern at 2.64, and health-related awareness at 2.62 The sub-divisions of health-improvement lifestyle show social emotion (2.87), food (2.66). favorite food (2.59), and leisure activities (2.52), in this order for higher points. It further shows health awareness (2.47) and safety awareness (2.40), lower points than those in health management pattern . 3. In the area of using leisure time for health-improvement, males, older people, married, and people with higher income earn higher marks. And, in the area of food management, the older and married earn higher marks . In the area of favorite food management, females, lower-income bracket, and lower-educated show higher degree of practice , while in the area of social emotion management, the older. married, and higher-income bracket show higher marks. In addition, in the area of health awareness, the older, married, and people with higher-income show higher degree of practice. 4. To look at correlation by overall and divisional health-improvement practice degree , this researcher has analyzed the data using Person's correlation coefficient. The lifestyle shows significant correlation with its six sub-divisions, and use of leisure time, food, and health awareness all show significant correlation with their sub-divisions. And. the social emotion and safety awareness show significant correlation with all sub-divisions except favorite food management.

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Temperament and Character Patterns of ADHD Children in a Community (지역사회 주의력결핍 과잉행동장애 아동의 기질 및 성격 특성)

  • Cho Soo-Churl;Kim Boong-Nyun;Jung Dong-Sun;Hwang Jun-Won;Shin Min-Sup;Lyoo In-Kyoon;Kim Jae-Won;Go Bock-Ja;Lee Sang-Eun;Jung Sun-Woo;Kim Hyo-Won
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.17 no.2
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    • pp.124-130
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    • 2006
  • Objectives : The objective of this study was to evaluate the differences in patterns of temperament and character, as assessed by the Junior Temperament and Character Inventory (JTCI), between the children with attention-deficit/hyperactivity disorder (ADHD) and the control group in a community sample. In addition, we examined the potential differences on JTCI profiles according to the ADHD subtypes. Methods : Parents of 185 ADHD subjects (mean age $9.0{\pm}1.7$ years), as diagnosed by the DISC-IV, and 185 age- and gender-matched comparison children have completed the parent's version of the JTCI. Results : The ADHD group scored significantly higher in Novelty Seeking and lower in Persistence than the comparison group on JTCI. However, there were no significant differences in the temperament or character profiles by the ADHD subtypes. Conclusion : The results of this study suggest that the temperamental factors of higher Novelty Seeking and lower Persistence are related to ADHD. The temperament or character profiles in this study do not provide support for the distinctiveness of the ADHD subtypes.

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Selenium Inhibits Metastasis of Murine Melanoma Cells through the Induction of Cell Cycle Arrest and Cell Death

  • Song, Hyun-Keun;Hur, In-Do;Park, Hyun-Jin;Nam, Joo-Hyung;Park, Ga-Bin;Kong, Kyoung-Hye;Hwang, Young-Mi;Kim, Yeong-Seok;Cho, Dae-Ho;Lee, Wang-Jae;Hur, Dae-Young
    • IMMUNE NETWORK
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    • v.9 no.6
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    • pp.236-242
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    • 2009
  • Background: Melanoma is the most fatal form of skin cancer due to its rapid metastasis. Recently, several studies reported that selenium can induce apoptosis in melanoma cells. However, the precise mechanism remains to be elucidated. In this study, we investigated the effect of selenium on cell proliferation in murine melanoma and on tumor growth and metastasis in C57BL/6 mice. Methods: Cell proliferation was measured by MTT assay in selenium-treated melanoma cells. Cell cycle distribution was analysized by staining DNA with propidum iodide (PI). mRNA and protein expression related to cell cycle arrest was measured by reverse transcription PCR and western blot. Tumor growth and metastasis was measured by in vivo model. Results: Selenium was suppressed the proliferation of melanoma cells in a dose dependent manner. The growth inhibition of melanoma by selenium was associated with an arrest of cell cycle distribution at G0/G1 stage. The mRNA and protein level of CDK2/CDK4 was suppressed by treatment with selenium in a time-dependent manner. In vivo, tumor growth was not suppressed by selenium; however tumor metastasis was suppressed by selenium in mouse model. Conclusion: These results suggest that selenium might be a potent agent to inhibit proliferative activity of melanoma cells.

Responses of Misgurnus anguillicaudatus and Cyprinus carpio Fed on Disease Resistant(OsCK1) Rice Variety (병저항성 GM(OsCK1)벼가 미꾸리(Misgurnus anguillicaudatus)및 잉어(Cyprinus carpio)에 미치는 영향)

  • Oh, Sung-Dug;Lee, Kijong;Park, Soo-Yun;Lee, Dae-Yong;Sohn, Soo-In;Kim, Min-Young;Ryu, Tae-Hun
    • Korean Journal of Environmental Agriculture
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    • v.32 no.3
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    • pp.231-239
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    • 2013
  • BACKGROUND: The disease resistant (OsCK1) rice was generated by inserting choline kinase (CK1) and phosphinothricin acetyltransferase (PAT) genes isolated from Oriza sativa and Streptomyces hygroscopicus into the genome of rice (Nakdongbyeo). With the potential problems of safety, the non-target organism evaluation is required as an essential element for the environmental risk assessment of genetically modified (GM) crops. In present study, we studied the effects on survival of Misgurnus anguillicaudatus and Cyprinus carpio, commonly used as a model organism in ecotoxicological studies. METHODS AND RESULTS: The M. anguillicaudatus and C. carpio were fed on disease resistant (OsCK1) rice and non-genetically modified (non-GM) rice (Nakdongbyeo) to 0, 10, 100, 1,000 and 5,000 mg/L, as treatment concentration respectively. The OsCK1 rice used for the test was confirmed to have the OsCK1/PAT gene expression by the PCR and ELISA analysis. Feeding test showed that no significant differences in cumulative immobility and abnormal response of M. anguillicaudatus and C. carpio fed on between OsCK1 rice and non-GM rice. The 96hr-$LC_{50}$ values showed no difference between OsCK1 rice (>5,000 mg/L) and non-GM rice (>5,000 mg/L). CONCLUSION(S): The results of this study suggested that there was no significant difference in toxicity for M. anguillicaudatus and C. carpio between OsCK1 rice and non-GM counterparts.

Alternative Carcinogenicity Screening Assay Using Colon Cancer Stem Cells: A Quantitative PCR (qPCR)-Based Prediction System for Colon Carcinogenesis

  • Bak, Yesol;Jang, Hui-Joo;Shin, Jong-Woon;Kim, Soo-Jin;Chun, Hyun woo;Seo, Ji-Hye;No, Su-Hyun;Chae, Jung-il;Son, Dong Hee;Lee, Seung Yeoun;Hong, Jintae;Yoon, Do-Young
    • Journal of Microbiology and Biotechnology
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    • v.28 no.4
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    • pp.645-651
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    • 2018
  • The carcinogenicity of chemicals in the environment is a major concern. Recently, numerous studies have attempted to develop methods for predicting carcinogenicity, including rodent and cell-based approaches. However, rodent carcinogenicity tests for evaluating the carcinogenic potential of a chemical to humans are time-consuming and costly. This study focused on the development of an alternative method for predicting carcinogenicity using quantitative PCR (qPCR) and colon cancer stem cells. A toxicogenomic method, mRNA profiling, is useful for predicting carcinogenicity. Using microarray analysis, we optimized 16 predictive gene sets from five carcinogens (azoxymethane, 3,2'-dimethyl-4-aminobiphenyl, N-ethyl-n-nitrosourea, metronidazole, 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone) used to treat colon cancer stem cell samples. The 16 genes were evaluated by qPCR using 23 positive and negative carcinogens in colon cancer stem cells. Among them, six genes could differentiate between positive and negative carcinogens with a p-value of ${\leq}0.05$. Our qPCR-based prediction system for colon carcinogenesis using colon cancer stem cells is cost- and time-efficient. Thus, this qPCR-based prediction system is an alternative to in vivo carcinogenicity screening assays.

Bit-Rate Control Using Histogram Based Rate-Distortion Characteristics (히스토그램 기반의 비트율-왜곡 특성을 이용한 비트율 제어)

  • 홍성훈;유상조;박수열;김성대
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.24 no.9B
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    • pp.1742-1754
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    • 1999
  • In this paper, we propose a rate control scheme, using histogram based rate-distortion (R-D) estimation, which produces a consistent picture quality between consecutive frames. The histogram based R-D estimation used in our rate control scheme offers a closed-form mathematical model that enable us to predict the bits and the distortion generated from an encoded frame at a given quantization parameter (QP) and vice versa. The most attractive feature of the R-D estimation is low complexity of computing the R-D data because its major operation is just to obtain a histogram or weighted histogram of DCT coefficients from an input picture. Furthermore, it is accurate enough to be applied to the practical video coding. Therefore, the proposed rate control scheme using this R-D estimation model is appropriate for the applications requiring low delay and low complexity, and controls the output bit-rate ad quality accurately. Our rate control scheme ensures that the video buffer do not underflow and overflow by satisfying the buffer constraint and, additionally, prevents quality difference between consecutive frames from exceeding certain level by adopting the distortion constraint. In addition, a consistent considering the maximum tolerance BER of the voice service. Also in Rician fading channel of K=6 and K=10, considering CLP=$10^{-3}$ as a criterion, it is observed that the performance improment of about 3.5 dB and 1.5 dB is obtained, respectively, in terms of $E_b$/$N_o$ by employing the concatenated FEC code with pilot symbols.

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Management of Grapholita molesta and Carposina sasakii Using Mating Disruption in Non-Chemical or Organic Apple Orchards (무농약·유기재배 사과원에서 교미교란제를 이용한 복숭아순나방과 복숭아심식나방의 방제)

  • Lee, Sun-Young;Choi, Kyung-Hee;Do, Yun-Su;Lee, Soon-Won;Yoon, Changmann;Kim, Gil-Hah
    • Korean journal of applied entomology
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    • v.53 no.2
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    • pp.103-110
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    • 2014
  • The efficacy of mating disruptors MD-IKR (Isomate-KR) and MD-CR (Confuser-R) for controlling Grapholita molesta (Busck) and Carposina sasakii (Matsumura) was evaluated in non-chemical or organic apple orchards. For G. molesta, the efficacy of MD-IKR and MD-CR in Chilgok was 99.8 and 99.8% (2011) and 92.4 and 96.7% (2012), respectively, showing different mating reduction values. The efficacy of MD-IKR and MD-CR in Cheongsong was 99.1 and 92.8% (2011) and 99.6 and 99.6% (2012), respectively. For C. sasakii, the efficacy of MD-IKR and MD-CR was 100% at Chilgok and Cheongsong in 2011 and 2012. Evaluation of the shooting and fruit damage rates showed that the efficacy of the mating disruptors in controlling G. molesta and C. sasakii was better than that of the non-control. However, there was no significant control difference between using the mating disruptors and the conventional control. No difference in the efficacy of the two mating disruptors was observed. We believe that MD-IKR could be an alternative to MD-CR.