• Nuclear Engineering and Technology
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• v.51 no.4
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• pp.968-976
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• 2019

This paper presents a number of verification case studies for a recently developed sensitivity/uncertainty code package. The code package, ROMUSE (Reduced Order Modeling based Uncertainty/Sensitivity Estimator) is an effort to provide an analysis tool to be used in conjunction with reactor core simulators, in particular the Virtual Environment for Reactor Applications (VERA) core simulator. ROMUSE has been written in C++ and is currently capable of performing various types of parameter perturbations and associated sensitivity analysis, uncertainty quantification, surrogate model construction and subspace analysis. The current version 2.0 has the capability to interface with the Design Analysis Kit for Optimization and Terascale Applications (DAKOTA) code, which gives ROMUSE access to the various algorithms implemented within DAKOTA, most importantly model calibration. The verification study is performed via two basic problems and two reactor physics models. The first problem is used to verify the ROMUSE single physics gradient-based range finding algorithm capability using an abstract quadratic model. The second problem is the Brusselator problem, which is a coupled problem representative of multi-physics problems. This problem is used to test the capability of constructing surrogates via ROMUSE-DAKOTA. Finally, light water reactor pin cell and sodium-cooled fast reactor fuel assembly problems are simulated via SCALE 6.1 to test ROMUSE capability for uncertainty quantification and sensitivity analysis purposes.

• Transactions of the Korean Society of Pressure Vessels and Piping
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• v.19 no.2
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• pp.163-170
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• 2023

Since spent nuclear fuel assemblies (SFA) are transported to interim storage or final disposal facility after cooling the decay heat, finite element analysis (FEA) with simplification is widely used to show their integrity against cladding failure to cause dispersal of radioactive material. However, there is a lack of research addressing the comprehensive impact of shape and element simplification on analysis results. In this study, for the optimization of a typical pressurized water reactor SFA, different types of finite element models were generated by changing number of fuel rods, fuel rod element type and assembly length. A series of FEA in use of these different models were conducted under a shock load data obtained from surrogate fuel assembly transportation test. Effects of number of fuel rods, element type and length of assembly were also analyzed, which shows that the element type of fuel rod mainly affected on cladding strain. Finally, an optimal finite element model was determined for other practical application in the future.

• Journal of Korea Water Resources Association
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• v.56 no.5
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• pp.337-345
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• 2023

Monitoring river microplastics is a challenging task since it is a time-consuming and high-cost process. The use of a physical model to have a better understanding of river microplastics' behaviors can complement the challenging monitoring process. However, there have been very limited studies on modeling river microplastics. In this study, therefore, we evaluated the applicability of one commonly used river water quality model, i.e., the Water Quality Analysis Simulation Program (WASP), in simulating the microplastic concentration in the river environment. We simulated the microplastic concentration in the Anyangcheon stream using the WASP's biochemical oxygen demand (BOD) and suspended solid (SS) variables as possible surrogate variables for the microplastics. Simulation analyses indicate that the SS state variable performs better than the BOD state variable to mimic the observed concentrations of microplastics. This is because of the characteristics of each water quality parameter; the BOD variable, a biochemical indicator, is inappropriate for modeling the behaviors of microplastics, which have generally constant biochemical features. In contrast, the SS variable, which has similar physical behaviors, followed the observed patterns of the microplastic concentrations well. To build a more advanced and accurate model for simulating the microplastic concentration, comprehensive and long-term monitoring studies of the river microplastics under different environmental conditions are needed, and the unit of microplastic concentration should be carefully addressed before its modeling application.

• Journal of Dental Anesthesia and Pain Medicine
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• v.15 no.4
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• pp.229-233
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• 2015

Background: Although water chambers are often used as surrogate blood-warming devices to facilitate rapid warming of red blood cells (RBCs), these cells may be damaged if overheated. Moreover, filtered and irradiated RBCs may be damaged during the warming process, resulting in excessive hemolysis and extracellular potassium release. Methods: Using hand-held syringes, each unit of irradiated and leukocyte-filtered RBCs was rapidly passed through a water chamber set to different temperatures (baseline before blood warming, $50^{\circ}C$, $60^{\circ}C$, and $70^{\circ}C$). The resulting plasma potassium and free hemoglobin levels were then measured. Results: Warming RBCs to $60^{\circ}C$ and $70^{\circ}C$ induced significant increases in free hemoglobin (median [interquartile ranges] = 60.5 mg/dl [34.9-101.4] and 570.2 mg/dl [115.6-2289.7], respectively). Potassium levels after warming to $70^{\circ}C$ ($31.4{\pm}7.6mEq/L$) were significantly higher compared with baseline ($29.7{\pm}7.1mEq/L$; P = 0.029). Potassium levels were significantly correlated with storage duration after warming to $50^{\circ}C$ and $60^{\circ}C$ (r = 0.450 and P = 0.001; r = 0.351 and P = 0.015, respectively). Conclusions: Rapid warming of irradiated leukoreduced RBCs to $50^{\circ}C$ may not further increase the extracellular release of hemoglobin or potassium. However, irradiated leukoreduced RBCs that have been in storage for long periods of time and contain higher levels of potassium should be infused with caution.

• Proceedings of the Korea Water Resources Association Conference
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• 2020.06a
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• pp.47-47
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• 2020

하천 유사량 자료는 하천관리를 위해 기초적으로 활용되는 자료로 하천의 유지관리를 위한 유사량 자료의 측정은 필수적이다. 따라서, 현재 국내에서는 전국에 138개소의 국가유사량관측망에서 지속적인 유사량 측정을 수행하고 있지만, 기존의 재래식 부유사 채집기를 이용한 부유사 측정을 수행하고 있어 연간 약 20개소 내외에서만 직접조사가 수행되고 있고, 2019년도 기준 전국 138개소 중에서 2006년~2018년 동안 최소 1회 이상 유사량 측정을 수행한 지점은 40개소로 국가 유사량관측망의 약 29% 지점에 대해서만 조사가 수행되고 있다. 해외의 경우에도 기존 재래식 채집기를 통한 유사량 관측을 주로 수행하고 있지만 최근에는 기존 채집기를 이용한 유사량 조사방법의 고비용·저효율로 인한 시공간적 한계로 인해 대안기술이 개발되고 있다. 특히, 최근 해외에서는 ADCP를 활용한 유사량 측정 기술이 기존 부유사 채집기를 이용한 유사량 조사방법의 대안으로 시도되고 있다. ADCP를 이용한 유사량 측정방법은 ADCP의 초음파산란도를 활용하여 간접적으로 부유사의 농도를 추정하는 기술로 ADCP를 이용하여 유량자료과 함께 유사량 자료를 확보할 수 있을 것으로 기대되는 기술이다. 특히, 기존에 설치된 국가하천 자동유량측정장치(H-ADCP)에 적용이 가능하다면 다지점에서의 지속적인 유량측정과 함께 부유사 농도의 측정이 가능할 것으로 기대되고 있다. 이에 본 연구에서는 기존 국가하천에 설치되어 있는 자동유량측정장치(H-ADCP)의 초음파산란도를 활용한 부유사농도 측정 기술의 적용성을 검토하였다. 적용성의 검토를 위해 2016년 진동지점에서 수집된 H-ADCP 원시자료를 사용하여 초음파산란도를 활용한 부유사농도 측정 방법을 시범적으로 적용하였다. 적용결과, 실측 부유사농도와 H-ADCP로부터 추정된 부유사 농도를 비교를 통해서 H-ADCP를 활용한 부유사농도 측정 방법의 가능성을 확인할 수 있었지만, 기술적인 보완 및 개선이 필요할 것으로 판단되었다. 추후에는 지속적인 연구를 통해 ADCP 유사량 측정기술이 개발된다면 기존 부유사 채집기를 이용한 유사량 측정 방법의 대안으로 유사량 조사를 목적으로 활용이 될 수 있을 것으로 기대한다.

• Journal of Korea Water Resources Association
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• v.51 no.11
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• pp.989-998
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• 2018

Connectivity between water source and demand node can be served as a critical system performance indicator of the degree of water distribution network (WDN)' failure severity under abnormal conditions. Graph theory-based approaches have been widely applied to quantify the connectivity due to WDN's graph-like topological feature. However, most previous studies used undirected-unweighted graph theory which is not proper to WDN. In this study, the directed-weighted graph theory was applied for WDN connectivity analyses. We also proposed novel connectivity indicators, Source-to-Node Shortest Pathway (SNSP) and SNSP-Degree (SNSP-D) which is an inverse of the SNSP value, that does not require complicate hydraulic simulation of a WDN of interest. The proposed SNSP-D index was demonstrated in total 42 networks in J City, South Korea in which Pearson Correlation Coefficient (PCC) between the proposed SNSP-D and four other system performance indicators was computed: three resilience indexes and an energy efficiency metric. It was confirmed that a system representative value of the SNSP-D has strong correlation with all resilience and energy efficiency indexes (PCC = 0.87 on average). Especially, PCC was higher than 0.93 with modified resilience index (MRI) and energy efficiency indicator. In addition, a multiple linear regression analysis was performed to identify the system hydraulic characteristic factors that affect the correlation between SNSP-D and other system performance indicators. The proposed SNSP is expected to be served as a useful surrogate measure of resilience and/or energy efficiency indexes in practice.

• Journal of Korea Water Resources Association
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• v.54 no.11
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• pp.969-983
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• 2021

Evapotranspiration, one of the hydrometeorological components, is considered an important variable for water resource planning and management and is primarily used as input data for hydrological models such as water balance models. The FAO56 PM method has been recommended as a standard approach to estimate the reference evapotranspiration with relatively high accuracy. However, the FAO56 PM method is often challenging to apply because it requires considerable hydrometeorological variables. In this perspective, the Hargreaves equation has been widely adopted to estimate the reference evapotranspiration. In this study, a set of parameters of the Hargreaves equation was calibrated with relatively long-term data within a Bayesian framework. Statistical index (CC, RMSE, IoA) is used to validate the model. RMSE for monthly results reduced from 7.94 ~ 24.91 mm/month to 7.94 ~ 24.91 mm/month for the validation period. The results confirmed that the accuracy was significantly improved compared to the existing Hargreaves equation. Further, the evaporative demand drought index (EDDI) based on the evaporative demand (E₀) was proposed. To confirm the effectiveness of the EDDI, this study evaluated the estimated EDDI for the recent drought events from 2014 to 2015 and 2018, along with precipitation and SPI. As a result of the evaluation of the Han-river watershed in 2018, the weekly EDDI increased to more than 2 and it was confirmed that EDDI more effectively detects the onset of drought caused by heatwaves. EDDI can be used as a drought index, particularly for heatwave-driven flash drought monitoring and along with SPI.

• Korean Journal of Ecology and Environment
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• v.39 no.1 s.115
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• pp.62-72
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• 2006

Biological health in aquatic environments has been assessed by several approaches using various bio-taxa. Especially, fish has been identified as one of the best ecological indicators for an integrative health assessments in aquatic environments. In this preliminary study, the necropsy-based approach using the Health Assessment Index (Adams et al., 1993; HAI, Blazer, 2000), was employed for the assessments of aquatic environments influenced by effluent water from wastewater disposal plants (WDP) near a urban stream (i.e., Cap-Stream). For the impact analysis from the effluents, we developed 10 metric necropsy-based model including $M_l\;skin,\;M_2\;fin,\;M_3\;thymus,\;M_4\;spleen,\;M_5\;hindgut,\;M_6\;kidney,\;M_7\;liver.\;M_8\;eyes,\;M_9\;gill,\;and\;M_{10}$ pseudobranch. We set up duplicate controls (natural upstream water plus 5 fishes in each control tank) and duplicate treatments (effluent water from the WDP plus 5 fishes in each treatment tank) in the laboratory. Preliminary results showed that HAI values in the controls were zero, indicating an excellent condition by the criteria of HAI, while the HAI values in the treatments ranged between 40 and 150, indicating a poor condition. Also, various health conditions, based on the index of biological integrity (IBI), species richness, tolerance guilds, and trophic guilds supported the HAI approach. The HAI approach, not applied in Korea, not may be used as an surrogate fer ecological health assessment in lotic ecosystems.

• Ocean Science Journal
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• v.40 no.3
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• pp.127-143
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• 2005

The taxonomic sufficiency approach has been proposed as a surrogate for the typical analysis of species-abundance data, especially in conditions involving prominent pollution gradients. Here, we evaluate the use of taxonomic sufficiency with infralittoral macrobenthic data derived from samples taken in a moderate polluted subtropical environment in southeastern Brazil, analysing five taxonomic levels and including two functional levels throughout polychaete feeding guilds and trophic groups. The data were collected seasonally at nine stations and studied for two abundance data series (0.5 and 1.0 mm sieve mesh-size). The results showed a similar ordination pattern between the two sieve mesh-size, but with the 0.5 mm sieve data a different pattern was observed during austral summer. A slight loss of information was detected using genus, family, polychaete species and their feeding guilds as taxonomic/functional units. These results together with those of the cost! benefit ratio, suggested that the family level seemed to be sufficient to detect the impact caused by moderate pollution in this shallow-water, subtropical environment. In additional, through the use of feeding guilds, similar patterns are obtained. Correlation analysis showed that chlorophyll a, total organic matter, zinc, and chromium sediment content were the variables that best explained the biological pattern observed and not always the best correlation coefficient occurring at the species level. The feeding guild approach seems to be useful and generates interpretable results similar to those obtained with the species level of the whole macroinfauna. The results showed an important cost reduction in the sample processing, suggesting that it is possible to adopt a coarser taxonomic level monitoring program even in species-rich communities.

• Toxicological Research
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• v.33 no.4
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• pp.283-290
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• 2017

The host immune system is the first line of host defense, consisting mainly of innate and adaptive immunity. Immunity must be maintained, orchestrated, and harmonized, since overactivation of immune responses can lead to inflammation and autoimmune diseases, while immune deficiency can lead to infectious diseases. We investigated the regulation of innate and adaptive immune cell activation by Artemisia capillaris and its components (ursolic acid, hyperoside, scopoletin, and scopolin). Macrophage phagocytic activity was determined using fluorescently labeled Escherichia coli, as an indicator of innate immune activation. Concanavalin A (ConA)- and lipopolysaccharide (LPS)-induced splenocyte proliferation was analyzed as surrogate markers for cellular and humoral adaptive immunity, respectively. Neither A. capillaris water extract (WAC) nor ethanol extract (EAC) greatly inhibited macrophage phagocytic activity. In contrast, WAC suppressed ConA- and LPS-induced proliferation of primary mouse splenocytes in a dose-dependent manner. Similarly, EAC inhibited ConA- and LPS-induced splenocyte proliferation. Oral administration of WAC in mice decreased ConA- and LPS-induced splenocyte proliferation, while that of EAC suppressed LPS-induced splenocyte proliferation. Repeated administration of WAC in mice inhibited ConA- and LPS-induced splenocyte proliferation. Ursolic acid, scopoletin, and scopolin reduced ConA- and LPS-induced primary mouse splenocyte proliferation, while hyperoside did not show such activity. These results indicate that A. capillaris and its components, ursolic acid, scopoletin, and scopolin, suppress ConA- and LPS-induced adaptive immune cell activation. The results suggest that A. capillaris is useful as a regulator of adaptive immunity for diseases involving excessive immune response activation.