Journal of the Korean Applied Science and Technology
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v.36
no.2
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pp.592-599
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2019
This study is to stabilize insoluble and unstable active ingredient which is Idebenone (INCI name: hydroxydecyl ubiquinone) in a multi-lamellar vesicle (MLV) and to stabilize it in the skin care cosmetics. Idebenone is good effective raw material in the treatment of Alzheimer's disease in the medical field and a powerful antioxidant in dermatology. It is well known as a substance that inhibits the formation of melanin and cleans the skin pigment. However, it did not dissolve in any solvent and it was difficult to apply in cosmetic applications. Niosome vesicle was able to develop a nano-particle by making a multi-layer of idebenone encapsulated with a nonionic surfactant, hydrogenated lecithin and glycine soja (soybean) sterols and passing it through a high pressure microfluidizer. Idebenone niosome vesicle (INV) has been developed to have the ability to dissolve transparently in water and to promote transdermal penetration. The appearance of the INV was a yellowish liquid having specific odor, and the particle size distribution of INV was about 10~80 nm. The pH was 5~8 (mean=6.8). This capsulation with idebenone was stored in a $45^{\circ}C$ incubator for 3 months and its stability was observed and quantitatively measured by HPLC. As a result, the stability of the sample encapsulated in the niosome vesicle (97.5%) was about 66.3% higher than that of the non-capsule sample of 32.5%. Idebenone 1% INV was used for the efficacy test and clinical trial evaluation as follows. The anti-oxidative activity of INV was 38.2%, which was superior to that of 12.8% tocopherol (control). The melanin-reducing effect of B16 melanoma cells was better than INV (17.4%) and Albutin (control) (9.6%). Pro-collagen synthesis rate was 128.2% for INV and 89.3% for tocopherol (control). The skin moisturizing effect was 15.5% better than the placebo sample. The elasticity effect was 9.7% better than the placebo sample. As an application field, INV containing 1% of idebenone is expected to be able to develop various functional cosmetic formulations such as skin toner, ampoule essence, cream, eye cream and sunblock cream. In addition, it is expected that this encapsulated material will be widely applicable to emulsifying agents for skin use in the pharmaceutical industry as well as the cosmetics industry.
Ham, Kahyun;Chung, Sunki;Choi, Mihwa;Yang, Seugran;Lee, Jaeyoung
Applied Chemistry for Engineering
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v.30
no.4
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pp.493-498
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2019
In polymer exchange membrane fuel cells, it is crucial to fabricate a highly active and thin Pt catalyst layer for the smooth mass transport of dissolved oxygen and water. Although a highly loaded platinum (Pt) catalyst based on the hydrothermal synthesis has been reported in several studies, its growing behaviors and kinetics were yet to be understood. In this study, we investigated the growth of Pt crystal in suspension after the reduction step depending on a stirring time and evaluated the electrochemical activity. For only a couple of hours in the early stage, Pt colloids were adsorbed on the Pt-carbon catalyst and the Pt crystal was grown. After that, the small Pt colloid was formed by another nucleation step, which did not involve the growth of Pt crystal. We reveal that the Pt-Carbon catalyst with stirring for 6 h showed a high activity toward the oxygen reduction reaction.
In the mid-eastern Yellow Sea, glacio-eustatic sea-level fluctuations and a regional tectonic subsidence have combined to represent an aggradational stacking pattern of sedimentary units during late Pleistocene-Holocene. The accumulated sediments are divisible into two-type units of Type-A and Type-B in high-resolution air-gun seismic profiles and the deep-drilled core of YSDP-105. Type-A unit largely comprises clast-rich coarse-grained sediments of non-marine to paralic origin, whereas Type-B unit consists mostly of tidal fine-grained sediments. Based on a bottom model of the sedimentary units, this study suggested a geoacoustic model of long-coring bottom layers at the YSDP-105 drilling site of the mid-eastern Yellow Sea. The geoacoustic model of 64-m depth below the seafloor with four-layer geoacoustic units was reconstructed in continental shelf strata at 45 m in water depth. For actual modeling, the geoacoustic property values of the models were compensated to in situ depth values below the seafloor using the Hamilton modeling method. We suggest that the geoacoustic model will be used for geoacoustic and underwater acoustic experiments of mid- and low-frequency reflecting on the deep bottom layers in the mid-eastern Yellow Sea.
Myeonghwalsanseong Fortress and Namsansinseong Fortress in Gyeongju are one of the few that have accurate records of when and who constructed the structures. Based on the monument commemorating the construction of Myeonghwalsanseong Fortress and the construction technique and structure of the fortresses confirmed through excavation survey, it can be induced that Myeonghwalsanseong Fortress was built prior to the 7th century. Meanwhile, Namsansinseong Fortress is believed to have been erected in 679, with the exception of one part of the wall found in the northwestern valley that was built during the first construction period of 591. Referring to the construction method of these fortresses in the royal capital, Gyeongju, various recentlystudied fortresses were reviewed to estimate the construction periods. As a result, Haman Seongsansanseong Fortress, which takes similar form with Myeonghwalsanseong Fortress, is believed to have been built during the mid-6th century based on the construction method and supplementary work method(i.e. Bochuk). Yangdongsanseong Fortress in Gimhae and Singisanseong Fortress, similar in their construction method, are also believed to be from the same period. Meanwhile, Jusanseong Fortress of Goryeong, despite the similar construction technique used, the construction technique used for Bochuk or limited Bochuk imply a time gap. Separately, most of the remaining walls of Namsansinseong Fortress appear to date back to the additional construction period, and Sageunsanseong Fortress in Hamyang and Dadaesanseong Fortress in Geoje that show similar construction method are set for the same period. Such conclusion was drawn from straight layer piling using the refined rectangular stones found in the fortress and the supplementary part remaining thereof. In addition, the study discovered a cross-section triangular water hole at Yangdongsanseong Fortress in Gimhae and Sageunsanseong Fortress in Hamyang and the trace of wooden fences constructed before the construction of stone-wall, reaping outcomes rarely found in this region.
Journal of the Korean Crystal Growth and Crystal Technology
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v.29
no.5
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pp.215-221
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2019
Ceramic tiles, which are widely used as interior and exterior materials for construction, have recently been required to have pollution prevention function. In order to remove contaminants, many researches of ceramic tiles with hydrophilic surface property through $TiO_2$ coating and hydrophobic surface property by improving the flow of water droplets have been proceeded. Expecially, it is very important to develop a surface glaze having hydrophobicity through a sintering process above $1000^{\circ}C$ without an additional coating process and the degradation of mechanical properties. In this study, surface glaze with copper powder was applied to manufacture of ceramic tile. Contact angle of ceramic tile according to thickness of surface glaze layer was investigated after the conventional sintering process. The contact angle of the ceramic tile surface without the copper powder was shown to be $25.3^{\circ}$, which is close to hydrophilic surface. However, the contact angle was increased up to $109.8^{\circ}$ when the thickness of surface glaze with the copper powder was $150{\mu}m$. The excellent hydrophobic property of the surface glaze with copper powder was resulted from the cellular structure of copper particles on the glaze surface. In addition, the mechanical properties of the developed hydrophobic ceramic tiles such as bending strength, chemical resistance, abrasion resistance, and frost resistance were well maintained and meet the criteria of 'KS L 1001 Ceramic tile'.
To analyze the distribution of plant communities growing in river wetlands and the relationship between biotic and abiotic environmental factors, plant communities and environmental factors were investigated in river wetlands in the Boseong River. The Boseong River Wetland, the research site, consists of Hwapyeong Wetland, Bangujeong Wetland, and Seokgok Wetland. From June to September 2022, a plant community survey was conducted from the perspective of physiognomical vegetation, and the coverage of the emerging species followed the Braun-Blanquet scale. Plant species and the coverage of each species were recorded in the quadrant for plant community survey, and the cover of the quadrant, the total number of species, and the number of exotic species were measured as biological factors. As abiotic factors, altitude, orientation, inclination, soil texture, litter layer depth, dominant species diameter at breast height, and topography were recorded. In a total of 50 square plots, the most common Salix koreensis and Phragmites japonicus communities were found, and the community with the highest Shannon species diversity index was Phragmites japonicus-Echinochloa caudata community. As a result of ordination analysis by DCCA, the most significant clusters were separated according to topographic factors such as leeve, leeve slope, upper floodplain, lower floodplain, upper waterside, middle waterside, lower waterside, river island and opem water. As rare plants that need to be preserved in river wetlands, Hydrocharis dubia and Penthorum chinense were found in lower waterside, and it was found that the management of the river in the reservoir is necessary in line with the topographical distribution of ecosystem-disrupting plants, such as Paspalum distichum var. indutum.
Dimensionally stable electrodes are one of the important components in electrochemical water treatment processes. In the manufacturing of the dimensionally stable electrodes, the type of metal catalyst coated on the surface of the metal substrate, the coating and sintering methods substantially influence their performance and durability. In this study, using Ir-Ru-Ta ternary metal coating, various electrodes were prepared depending on the coating method under the same pre-treatment and sintering conditions, and its performance and durability were studied. As a coating method, brush and spray coating were used. As a result, the reduction in the amount of catalyst ink was achieved because more amount of metal could be coated for the electrode using spraying with the same amount of catalyst ink. In addition, the spray_2.0_3.0 electrode prepared by a specific spray coating method shows the phenomenon of cracking and the uniform coating of the ternary metal on the surface of the coating layer, and results in a high electrochemically active specific surface area, and the decomposition performance of 4-chlorophenol was superior to the other electrodes. However, it was found that there was no significant difference in durability depending on the coating method.
Journal of the Society of Cosmetic Scientists of Korea
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v.47
no.2
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pp.179-184
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2021
Stratum corneum known as a skin barrier, which maintains water in skin, is the outer layer of the skin. Natural moisturizing factors (NMF) are one of the constituents in stratum corneum and amino acids are the highest components among NMF. In this study, we designed stearic acid-based solid lipid nanoparticles (SLNs) for improved skin penetration of serine (Ser). Ser-capsulated SLN was manufactured by double-melting emulsification method. The mean particle size and zeta potential of SLNs were 256.30 ~ 416.93 nm and -17.60 ~ -35.27 mV, respectively. The higher the degree of hydrophobicity or hydrophilicity of emulsifiers, the smaller the particle size and the higher the stability and capsulation rate. In addition, skin penetration was conducted using SkinEthicTM RHE which is one of the reconstructed human epidermis models. The results of Ser penetration demonstrated that all SLNs enhanced than serine solution. The amount of enhanced Ser penetration from SLNs were approximately 4.1 ~ 6.2 times higher than that from Ser solution. Therefore, Ser-loaded SLN might be a promising drug delivery system for moisturizing formulation in cosmeceutical.
Journal of Practical Agriculture & Fisheries Research
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v.23
no.2
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pp.15-24
/
2021
For the aquaculture industrialization of surf clam (Tresus keenae), it is important to basic data on the marine environment of the habitat of surf clam (T. keenae). In this study, we investigated the marine environment of habitat of surf clam (T. keenae) and sought to basic data for the preparation of surf clam (T. keenae) for artificial seed production. The water temperature of the habitat of surf clam (T. keenae) was the lowest in winter and appeared high in summer. The salt concentration showed it range from 31.2 to 33.9 psu. The pH showed it range from 7.69 to 8.70, with high pH in winter and low pH in summer. The dissolved oxygen(DO) was showed it range from 6.20 to 10.24 mg / L and the autumn was relatively higher than the spring and winter. The species composition of phytoplankton was about 30 to 40 species, and most of them were diatoms. The abundance of seasonal phytoplankton showed it range from 23.5 to 61.3 cells / ml, showing seasonal differences. The expression of dominant species also showed a difference depending on the season. As for the particle size composition of the sediment, sandy silt was the most distributed. Flow velocities appeared at 50-80 cm / s in the southeast direction at ebb tide and at 60-100 cm / s in the northwest direction at flood tide. The results of this study can be used as basic data for providing knowledge about the habitat and marine environment of surf clam (T. keenae) and for studying shellfish that inhabit the sedimentary layer.
Forest fires increase the risk of subsequent soil erosion and mass movement in burned areas, even under rainfall conditions below landslide alert thresholds, by destroying plants and vegetation and causing changes to soil properties. These effects of forest fires can alter runoff in burned areas by altering soil composition, component minerals, soil water repellency, soil mass stability, and soil fabric. Heat from forest fires not only burns shallow organic matter and plants but also spreads below the surface, affecting soil constituents including minerals. This study analyzed X-ray diffraction and physical properties of topsoil and subsoil obtained from both burned and non-burned areas to identify the composition and distribution of clay minerals in the soil. Small amounts of mullite, analcite, and hematite were identified in burned soils. Vermiculite and mixed-layer illite/vermiculite (I/V) were found in topsoil samples from burned areas but not in those from non-burned areas. These findings show changes in soil mineral composition caused by forest fires. Expansive clay minerals increase the volume of soil during rainfall, degrading the structural stability of slopes. Clay minerals generated in soil in burned areas are therefore likely to affect the long-term stability of slopes in mountainous areas.
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