• Journal of Life Science
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• v.26 no.4
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• pp.475-483
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• 2016

The current study was conducted to evaluate beneficial effects of a new formula (CWC-9) using four traditional Oriental medicinal herbs, Cynanchum wilfordii, Rehmannia glutinosa, Polygala tenuifolia, and Acorus gramineus, on hippocampal cells and memory function. To examine the neuroprotective effects of a new four-herb extract, cell viability, cytotoxicity, and reactive oxygen species (ROS) assays were performed in HT22 cells and behavioral tests (Morris water maze and passive avoidance retention), Western blot, and immunohistochemistry were performed in a mouse model of focal cerebral ischemia. In HT22 hippocampal cells, pretreatment with CWC-9 resulted in significantly reduced glutamate-induced cell death with suppression of ROS accumulation caused by glutamate. In a mouse model of focal cerebral ischemia, we observed significant improvement of spatial and short-term memory function by treatment with CWC-9. Phosphorylated p38 mitogen-activated protein kinases (MAPK) in hippocampus of ischemic mice were decreased by treatment with CWC-9, but phosphorylated phosphatidylinositol-3 kinase (PI3K) and cAMP response element binding protein (CREB) were significantly enhanced. By immunohistochemical analysis, we confirmed higher expression of phosphorylation of CREB in the hippocampal neurons of CWC-9 treated mice. These results suggest that new multi-herb formula CWC-9 mainly exerted beneficial effects on cognitive function through regulation of neuro-protective signaling pathways associated with CREB.

• Journal of the Korean Applied Science and Technology
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• v.34 no.1
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• pp.66-82
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• 2017

Organosilicone-based surfactants consist of hydrophobic organosilicone groups coupled to hydrophilic polar groups. Organosilicone surfactants have been widely used in many industrial fields starting from polyurethane foam to construction materials, cosmetics, paints & inks, agrochemicals, etc., because of their low surface tension, lubricity, spreading, water repellency and thermal and chemical stability, resulted from the unique properties of organosilicone. Especially, trisiloxane surfactants, having low molecular weight organosilicone as hydrophobe, exhibit low surface tension and excellent wettability and spreadability, leading to their applications as super wetter/super spreader, but have the disadvantage of vulnerability to hydrolysis. A variety of trisiloxane surfactant structures are required to provide the functional improvement and the defect resolution for reflecting the necessities in the various applications. This review covers the synthetic schemes of reactive trisiloxanes as hydrophobic siloxane backbones, the main reaction schemes, such as hydrosilylation reaction, for coupling reactive trisiloxanes to hydrophilic groups, and the synthetic schemes of the main trisiloxane surfactants including polyether-, carbohydrate-, gemini-, bolaform-, double trisiloxane-type surfactants.

• Korean Journal of Agricultural Science
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• v.24 no.1
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• pp.41-49
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• 1997

The results on the chemical characteristics of the pork fed with fermented feeds are summarized as follows; 1) The pork treated with fermented feeds had lower fat and higher protein content than control pork in proximate compositions. It is considered to be the improvement of the quality. 2) It was not recognized to the difference of oxidation level among the sample porks. 3) Oleic acid was the highest concentration in the components of fatty acid of pork. The rate of the saturated and unsaturated fatty acids is 38.8 % : 59.9 % in the ordinary meat, 40.8 % : 57.8 % in the a high-grade meat, and 36.3 % : 62.0 % in the pork treated with fermented feeds. In addition, the essential fatty acid content of them is 14 %, 11.2 %, and 16.7%, respectively. 4) Glutamic acid was the highest composition in total amino acids and the essential amino acid content was 39% in both an ordinary meat and the pork treated with fermented feeds, and 14 % in high-grade meat. 5) It was no difference in the inorganic content among the samples. The water holding capacity by extraction meat juice was higher to 92 % in the pork treated with fermented feeds and 15.6 % in a loss in quantity by heating than others. Thus, the pork bred with fermented feeds was evaluated to be good in terms of processing and cooking.

• Journal of the Korean Association of Geographic Information Studies
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• v.23 no.1
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• pp.15-29
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• 2020

Recently, the incidence of flooding in Korea has decreased by the measures by central and local governments, however the scale of damage is increasing due to the improvement of living standard. One of the causes of such flood damage is natural causes such as rainfall exceeding the planned frequency of flood control under climate change. In addition, there are artificial causes such as encroachment of river spaces and management problems in upstream basins without consideration of downstream damage potential by regional development flood. In this study, in order to reduce the inundation damage caused by flooding of river, the situation at the time of inundation damage was reproduced by the detailed topographic data and 2D numerical model. Therefore, the effect of preparing various disaster prevention measures for the lowland was simulated in advance so that quantitative evaluation could be achieved. The target area is Taehwa river basin, where flooding was caused by the flooding of river waters caused by typhoon Chaba in October 2016. As a result of rainfall-discharge and two-dimensional analysis, the simulation results agree with the observed in terms of flood depth, flood arrival time and flooded area. This study examined the applicability of hydraulic analysis on river using two-dimensional inundation model, by applying detailed topographic data and it is expected to contribute to establish of disaster prevention measures.

• Journal of Environmental Impact Assessment
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• v.26 no.2
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• pp.105-113
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• 2017

Recently mountain tourism has been promoted and introduction of railroads with utilizing mountain resources is being planned. With the government policies to increase the share of eco-friendly transportation on railroad, national double-tracking of single rail and improvement projects are on going. However, the eco-friendly railroad policy suggests the environmental impact assessment items only on air quality, water quality, geographical/geological features, fauna/flora, natural/environmental resources, noise/ vibration, and recreation/landscape. And for fauna/flora and natural/environmental resources, confirming the presence of environmental protection zone is enough to satisfy legal requirement. This study suggested to evaluate environmental/ecological values with quantitative data. Evaluation indices and evaluation items have been selected to provide the data. Each of the subject map and railroad network was overlapped. The study selected naturalness and diversity as major indicators and calculated weight values of the items under the indicators, which are to be usd for the selection of the sites for railway development. This assessment method could be applied to the environmentally friendly construction of railroads in the future.

• Journal of Korean Tunnelling and Underground Space Association
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• v.19 no.1
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• pp.11-27
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• 2017

The road network system of major domestic urban areas such as city of Seoul was rapidly developed and regionally expanded. In addition, many kinds of life-lines such as electrical cables, telephone cables, water&sewerage lines, heat&cold conduits and gas lines were needed in order for urban residents to live comfortably. Therefore, most of the life-lines were individually buried in underground and individually managed. The utility tunnel is defined as the urban planning facilities for commonly installing life-lines in the National Land Planning Act. Expectation effectiveness of urban utility tunnels is reducing repeated excavation of roads, improvement of urban landscape; road pavement durability; driving performance and traffic flow. It can also be expected that ensuring disaster safety for earthquakes and sinkholes, smart-grind and electric vehicle supply, rapid response to changes in future living environment and etc. Therefore, necessity of urban utility tunnels has recently increased. However, all of the constructed utility tunnels are cut-and-cover tunnels domestically, which is included in development of new-town areas. Since urban areas can not accommodate all buried life-lines, it is necessary to study the feasibility assessment system for utility tunnel by urban patterns and capacity optimization for urban utility tunnels. In this study, we break away from the new-town utility tunnels and suggest a quantitative assessment model based on the evaluation index for urban areas. In addition, we also develop a program that can implement a quantitative evaluation system by subdividing the feasibility assessment system of urban patterns. Ultimately, this study can contribute to be activated the urban utility tunnel.

• Journal of Wetlands Research
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• v.18 no.4
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• pp.378-385
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• 2016

This study aims to suggest the framework of functional assessment on lotic area based on HGM(Hydrogeomorphic) approach targeting Wetland Protected Areas which are in the type of river channel, and to set up the fundamental data as a reference wetland. A total of 10 factors in terms of hydrology, biogeochemistry, plant habitat and animal habitat was analyzed based on the original approach of HGM and each Functional Capacity Index(FCI) of those factors was calculated. As the result of the modified FCI analysis, Damyang riverine wetland which is with artificial river bank had high values in the variables of area ratio of actual vegetation in the foreland, the number of plant per area and the area ratio of Salix spp., and those values were highly reflected on the factors of Nutrient Cycling(947,668.00), Species Richness and Maintain Characteristic Plant Communites(6.39) and Maintain Spatial Structure of Habitat(11.00). The Hanbando wetland which is keeping the natural bank had higher values in the variables of structural scale and species diversity, and the those values were highly reflected on the factors of Energy Dissipation(17,805.16), Subsurface Storage of Water(0.54), Removal of Imported Elements and Compounds(103,052.73), Maintain Characteristic Detrital Biomass(2.31), Maintenance of Interspersion and Connectivity (6.50), Species Diversity of Benthic macro-invertebrates(1.60) and Species Diversity of Vertebrate & Species Number of Other Animals(2.52/ 151.50), compared to the Damyang Riverine Wetland.

• Korean Journal of Agricultural Science
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• v.41 no.4
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• pp.473-480
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• 2014

Upon setting up a dedicated plastic greenhouse for tomato cultivation developed by the Rural Development Administration on the Gyehwa reclaimed land, this study was aimed at analyzing the problems can be occurred in the installation of plastic greenhouse on reclaimed lands as well as finding out solutions for improvement. A relatively cheaper wooden pile was used in the installation in order to supplement the soft ground conditions. Based on the results of ground investigation of the installation site, both the allowable bearing capacity and pulling resistance of the wooden pile with a diameter of 150 mm and a length of 10 m were computed and came out to be 30.645 kN. It was determined that the values were enough to withstand the maximum compressive force (17.206 kN) and the pullout force (20.435 kN) that are generally applied to the greenhouse footing. There are three problems aroused in the process of greenhouse installation, and the corresponding countermeasures are as follow. First, due to the slightly bent shape of the wooden pile, there were phenomenon such as deviation, torsion, and fracture when driving the pile. This could be prevented by the use of the backhoe (0.2) rotating tongs, which are holding the pile, to drive the pile while pushing to the direction of the driving and fixing it until 5 m below ground and applying a soft vibrating pressure until the first 2 m. Second, there exists a concrete independent footing between the column of the greenhouse and the wooden pile driven to the underground water level. Since it is difficult to accurately drive the pile on this independent footing, the problem of footing baseplate used to fix the column being off the independent footing was occurred. In order to handle with this matter, the diameter of the independent footing was changed from 200 mm to 300 mm. Last, after films were covered in the condition that the reinforcing frame and bracing are not installed, there was a phenomenon of columns being pushed away by the strong wind to the maximum of $11m{\cdot}s^{-1}$. It is encouraged to avoid constructions in winter, and the film covering jobs always to be done after the frame construction is completely over. The height of the independent footing was measured for 9 months after the completion of the greenhouse installation, and it was found to be within the margin of error meaning that there was no subsidence. The extent to the framework distortion and the value of inclinometers as well showed not much alteration. In other words, the wooden pile was designed to have a sufficient bearing capacity.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.6
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• pp.226-232
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• 2016

In the elderly, a lower muscle mass and higher body fat mass are induced by a lower level of physical activity. A negatively changed body composition with an advanced age can lead to a higher falling risk and rate of diseases. On the other hand, aerobic-type exercise positively influences the body composition and hyperlipidemia in the elderly. Therefore, this study examined the effects of aquarobic training for 12 weeks on the body composition and blood lipid levels in obese old women. The subjects (n = 31, body fat: 33.42%) completed a 12 week water based aerobic training at 12 - 13 of Borg Scale of intensity (three times per week, each session: an hour). The body composition was measured by bioelectrical impedance analysis (Inbody 770-Biospace, Seoul, Korea) and the concentrations of blood lipids (high-density lipids cholesterol (HDL), low-density lipids cholesterol (LDL), triglyceride (TG) total cholesterol (TC)) were determined at pre and post training. A paired t-test was used for data analysis with ${\alpha}=0.05$. In the results, the body composition (% body fat (p < 0.05) and waist circumference (p < 0.05)) were reduced significantly. The LDL (p < 0.05), TG (p < 0.001) and TC (p < 0.05) were reduced significantly. In conclusion, a 12 week aquarobic exercise program helps improve the body composition and concentrations of serum lipids. Therefore, aquarobic exercise can enhance lipolysis using fat as energy to induce an improvement of the body composition and induce hyperlipidemia.

• Journal of the Korea Concrete Institute
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• v.22 no.3
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• pp.409-417
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• 2010

This paper discusses a series of experiments including material improvement in order to ensure quality of grouting for the post-tensioned structure. In prestressed concrete, grouting refers to the construction procedure of filling empty space of duct enclosing with strands using cementitious material, To date, adequate quality control of the grouting has not been established in Korea because the relationship between the grouting and durability of post-tensioned structure is not well-recognized. The Korean standard does not consider the important material characteristic, wick effect, which is caused by strands in the ducts and current standard testing method unlikely quantify reasonable material segregation. As a result, the grout material, which meets the current material standards, may exhibit excessive bleeding water or shrinkage during construction. In this study, international codes and standards related to grouting were surveyed. The ratio of constituents and novel admixtures were suggested to meet equivalently with these standards. Performance of this enhanced grout was compared to common domestic grout using the international standard testing method. A series of mock-up specimens considering geometry of PC beam was constructed and grout flow pattern was observed as the grout was injected. It was observed that the grouting performance was highly influenced by material properties and filling characteristic can be varied depending on geometry of ducts.