• Korean Journal of Microbiology
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• v.7 no.1
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• pp.29-40
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• 1969

Two kinds of organic materials, powders of Salicornia and Oryza sativa L. wre added as a source of organic matter to the suspensions of saline soils(soil : water = 1:3) to be 4 per cent of dried saline soil grams. And then, the samples were incubated at $28^{\circ}C$ to improve the decomposition of organic materials by soil microflora. Resutls of this experiment are summarized as followings : 1) The pH of soil suspension showed its highest value on the second or third week after the treatments, which were similar to those of the soil microflora. Results of this experiment are summarized as follwings : 1) The pH of soil suspension showed its highest value on the second ot third week after the treatments, which were similar to those of the soil microflora populations. 2) Salinity increased up to the second week and the highest value of it appeared in the samples which were treated with the powder of Salicornia. In general, the salinity of all samples decreased on the third week after the treatment. The fact was assumed the possibilities of desalination from saline soil by the microbial actions. 3) Soil microflora such as bacteria, actinomycetes and fungi, were determined its populations soil microflora is to act as decomposer in soil. Both of the bacteria and actinomycytes population showed in the third weak after the tratment. In general, 30-years old of saline soil contained microbial population much more than those of 5-year old of saline soil. Salicornia powder favored the increase of both the bacteria and fungal population, and Oryza sativa L. seemed to have been a great role in increase of actinomycetes. Especially, fungal population of the untreated soil suspension contained higher microbial populations more than those of the soils treated with both of the organic materials. 4) Sugar contents of soil suspesions decreased remarkably on the first week after the treatments. 5) The amount of nitrate had similar tendency to those of population changes of soil microflora. Total acidity decreased continuously and the amount of potassium showed its highest value on the third week treatment. However, the amount of phosphorus was determined to be insignificant.

• ALGAE
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• v.35 no.1
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• pp.91-106
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• 2020

Incorporating renewable fuel into practice, especially from algae, is a promising approach in reducing fossil fuel dependency. Algae are an exceptional feedstock since they produce abundant biomass and oils in short timeframes. Algae also produce high-valued lipid products suitable for human nutrition and supplement. Achieving goals of producing algae fuels and high-valued lipids at competitive prices involves further improvement of technology, especially better control over cultivation. Manipulating microalgae cultivation conditions to prevent contamination is essential in addition to promoting optimal growth and lipid yields. Contamination of algal cultures is a major impediment to algae cultivation that can however be mitigated by choosing extremophile microalgae. This work describes the isolation of alkali-tolerant / alkaliphilic microalgae native to South Florida with ideal characteristics for cultivation. For that purpose, water samples from Lake Okeechobee were inoculated into Zarrouk's medium (pH 9-12) and incubated for 35 days. Selection resulted in isolation of three strains that were screened for biomass and lipid accumulation. Two alkali-tolerant algae Chloroidium sp. 154-1 and Chlorella sp. 154-2 were poor lipid accumulators. One of the isolates, the diatom Fistulifera sp. 154-3, was identified as a lipid accumulating, alkaliphilic organism capable of producing 0.233 g L^-1 d^-1 dry biomass and a lipid content of 20-30% dry weight. Lipid analysis indicated the most abundant fatty acid within Fistulifera sp. was palmitoleic acid (52%), or omega-7, followed by palmitic acid (17%), and then eicosapentanoic acid (15%). 18S rRNA phylogenetic analysis formed a well-supported clade with Fistulifera species.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.1
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• pp.11-17
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• 2015

Overconsumption of fructose results in dyslipidemia, hypertension, which have documented as a risk of cardiovascular diseases. This experimental study was designed to investigate the beneficial effects of Rubus coreanus Miq.(RCM) in high-fructose diet-induced metabolic syndrome. Animals were divided into three groups; Control group fed regular diet and tap water, fructose groups were fed the 65% high-fructose (HF) diet with/without RCM 100 mg/kg/day for 8 weeks, respectively. Chronic treatment with RCM significantly decreased body weight, fat weight and adipocyte size. Moreover, RCM significantly prevented the development of the metabolic disturbances such as hyperlipidemia and hypertension. RCM also led to increase in high density lipoprotein level in the HF group. In addition, RCM suppressed vascular cell adhesion molecule-1 (VCAM-1) expression and significantly recovered the levels of endothelial nitric oxide synthase (eNOS) expression in aorta. These results demonstrates that RCM may be a beneficial therapeutic for metabolic syndrome through the improvement of hyperlipidemia, obesity, and hypertension.

• Toxicological Research
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• v.28 no.4
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• pp.235-240
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• 2012

$^{99m}Tc$ tricarbonyl glycine monomers, trimers, and pentamers were synthesized and evaluated for their radiolabeling and in vivo distribution characteristics. We synthesized a $^{99m}Tc$-tricarbonyl precursor with a low oxidation state (I). $^{99m}Tc(CO)_3(H_2O)_3^+$ was then made to react with monomeric and oligomeric glycine for the development of bifunctional chelating sequences for biomolecules. Labeling yields of $^{99m}Tc$-tricarbonyl glycine monomers and oligomers were checked by high-performance liquid chromatography. The labeling yields of $^{99m}Tc$-tricarbonyl glycine and glycine oligomers were more than 95%. We evaluated the characteristics of $^{99m}Tc$-tricarbonyl glycine oligomers by carrying out a lipophilicity test and an imaging study. The octanol-water partition coefficient of $^{99m}Tc$ tricarbonyl glycine oligomers indicated hydrophilic properties. Single-photon emission computed tomography imaging of $^{99m}Tc$-tricarbonyl glycine oligomers showed rapid renal excretion through the kidneys with a low uptake in the liver, especially of $^{99m}Tc$ tricarbonyl triglycine. Furthermore, we verified that the addition of triglycine to prototype biomolecules (AGRGDS and RRPYIL) results in the improvement of radiolabeling yield. From these results, we conclude that triglycine has good characteristics for use as a bifunctional chelating sequence for a $^{99m}Tc$-tricarbonyl-based biomolecular imaging probe.

• Biomolecules & Therapeutics
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• v.25 no.3
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• pp.249-258
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• 2017

To examine the effect of biflorin, a component of Syzygium aromaticum, on memory deficit, we introduced a scopolamine-induced cognitive deficit mouse model. A single administration of biflorin increased latency time in the passive avoidance task, ameliorated alternation behavior in the Y-maze, and increased exploration time in the Morris water maze task, indicating the improvement of cognitive behaviors against cholinergic dysfunction. The biflorin-induced reverse of latency in the scopolamine-treated group was attenuated by MK-801, an NMDA receptor antagonist. Biflorin also enhanced cognitive function in a naïve mouse model. To understand the mechanism of biflorin for memory amelioration, we performed Western blot. Biflorin increased the activation of protein kinase C-${\zeta}$ and its downstream signaling molecules in the hippocampus. These results suggest that biflorin ameliorates drug-induced memory impairment by modulation of protein kinase C-${\zeta}$ signaling in mice, implying that biflorin could function as a possible therapeutic agent for the treatment of cognitive problems.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.10a
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• pp.748-753
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• 2005

Among processes to manufacture parts from footwear materials like upper leathers, one of the most essential processes is the cutting one optimally arranging lots of parts on raw footwear materials and cutting. A new nesting strategy was proposed for the 2-dimensional part layout by using a two-stage approach, where which can be effectively used for water jet cutting. In the initial layout stage, a SOAL(Self-Organization Assisted Layout) based on the combination of FCM(Fuzzy C-Means) and SOM was adopted. In the layout improvement stage, SA(Simulated Annealing) based approach was adopted for a finer layout. The proposed approach saves much CPU time through a two-stage approach scheme, while other annealing-based algorithm so far reported fur a nesting problem are computationally expensive. The proposed nesting approach uses the stochastic process, and has a much higher possibility to obtain a global solution than the deterministic searching technique. We developed the automatic nesting software of NST(ver.1.1) software for footwear industry by implementing of these proposed algorithms. The NST software was applied by the optimized automatic arrangement algorithm to cut without the loss of leathers. if possible, after detecting damage areas. Also, NST software can consider about several features in not only natural loathers but artificial ones. Lastly, the NST software can reduce a required time to implement generation of NC code. cutting time, and waste of raw materials because the NST software automatically performs parts arrangement, cutting paths generation and finally NC code generation, which are needed much effect and time to generate them manually.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2005.11a
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• pp.723-726
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• 2005

The two major obstacles in the application of IPMC to flapping actuators operated in the air are solvent loss and actuation force. In this paper, solvent loss of various IPMCs made of Nafion$^{TM}$117(183$\mu$m thickness) has been experimentally investigated to find out the best combination of cation and solvent for minimal solvent loss in IPMCs and higher actuation force. For this purpose. experiments for the internal solvent loss measurement of IMPCs have been conducted for various combinations of cation and solvent. From the experiments, it was found that heavy water showed improvement in the operating time up to more than two minutes. in the tip force measurement of IPMCs, it was found that smaller and thicker IPMCs produced larger tip forces. However, the shorter IPMCs generated reduced actuation displacements and created flapping motion with decreased natural frequency. For the design of flapping device actuated by 5mm wide, 10mm long, 0.2mm thick IPMCs were used in the stacked form. Since the actuation force is a few gram-force, we stacked five IPMCs to improve actuation force. To amply the actuation force, rack-and-pin ion type hinge was used for the flapping device and insect (Cicadidae) wing was attached to the stacked IPMC actuator. In the flapping test, the device could generate flapping angle of 15$^{\circ}$ at 6Hz excitation by 2.5 voltage square wave input.

• Journal of the Korean Society of Industry Convergence
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• v.3 no.4
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• pp.319-327
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• 2000

In this study, the hydraulic characteristics variation of flood level caused by tree-planting condition in channel section is evaluated through the examination and analysis of back water characteristics in a natural channel within urban area where the improvement is completed. The study channel is Sinchun runs through the center of Taegu metropolitan city. For the analysis, the comparative examination of runoff characteristics depend on tree- planting condition performed for the flood level of the most upstream point, and velocity of study channel when the project flood flows according to three cases that existing channel is improved to the pro-natural channel, the roughness condition of both riverside highlands is changed, and the composition rate of trees in the riverside highlands is changed. It is known that the variation ranges of the flood level increase remarkably in general, and of the velocity decrease from the result of the examination for the hydraulic characteristics parameters at the most upstream point depend on the tree-planting condition of the channel section when the project flood flows. From the results of the above study on the variation of the hydraulic characteristics according to the tree-planting condition in channel section, it is known that the hydraulic characteristics when the project flood flows in channel have close relationship with the section properties and the slope of channel.

• Korean Journal of Food Science and Technology
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• v.30 no.4
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• pp.751-758
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• 1998

Lipoxygenase-deficient soybeans, Jinpumkong (lipoxygenase-2, 3 lacking) and Jinpumkong 2 (lipoxygenase-1, 2, 3 lacking), were breeded for the improvement of beany flavor problem. The objectives of this study were to characterize and to examine the storage stability of two lipoxygenase-deficient soybeans by comparing with Hwangkeumkong having high lipoxygenase activity. The crude protein and crude lipid content of Jinpumkong 2 were lower than those of Hwkangkeumkong and Jimpumkong. All soybean samples were middle-sized and yellow-coated seeds. The rate of water uptake and trypsin inhibitor activity of Jinpumkong were greater than those of others. The cooking rate of Hwangkeumkong was the highest among all. The lipoxygenase activity of Hwangkeumkong was decreased when the soybeans were stored at $40^{\circ}C$ for 96hrs at 90% RH which is the condition of accelerated aging. After accelerated aging, the germination ratio of Hwangkeumkong was not changed but the ratio and speed of germination dropped rapidly in Jinpumkong and Jinpumkong 2.

• Nutrition Research and Practice
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• v.9 no.5
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• pp.489-495
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• 2015

BACKGROUND/OBJECTIVES: The present study was conducted to investigate the effects of dried Momordica charantia aqueous extracts (MCA) and ethanol extracts (MCE) on obesity and lipid profiles in mice fed a high-fat diet. MATERIALS/METHODS: Forty two ICR mice were randomly divided into six groups. The normal group was fed a basal diet, and other groups were fed a 45% high-fat diet (HFD) for 7 weeks. The normal and HFD groups were also orally administered distilled water each day for 7 weeks. The remaining groups received Momordica charantia extract (0.5 or 1.0 g/kg/day MCA, and 0.5 or 1.0 g/kg/day MCE). In order to measure the anti-obesity and lipid profile improvement effects, body and visceral tissue weight, lipid profiles, plasma insulin levels, hepatic malondialdehyde (MDA) levels and superoxide dismutase (SOD) activity were measured. RESULTS: Both MCA and MCE significantly decreased body and visceral tissue weight relative to those of the HFD group (P < 0.05). Additionally high doses of MCE and MCA significantly reduced the plasmatic insulin levels compared to the HFD groups (P < 0.05) to concentrations comparable to those found in the normal group. MCA and MCE supplementation also significantly modulated the lipid profiles in plasma, liver, and feces compared to mice fed the HFD (P < 0.05). Furthermore MCA and MCE significantly increased hepatic SOD activity, and reduced MDA generation in the liver of the HFD mice (P < 0.05). CONCLUSIONS: Results from the present study suggest that Momordica charantia extracts have anti-obesity effects and the ability to modulate lipid prolife of mice fed a HFD by suppressing body weight gain, visceral tissue weight, plasma and hepatic lipid concentrations, and lipid peroxidation along with increasing lipid metabolism.