Beneficial Effect of Rubus Coreanus Miq in a Rat Model of High Fructose Diet-induced Metabolic Syndrome
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Kho, Min Chul
(College of Korean Medicine, Wonkwang University)
Lee, Yun Jung (College of Korean Medicine, Wonkwang University) Yoon, Jung Joo (College of Korean Medicine, Wonkwang University) Kang, Dae Gill (College of Korean Medicine, Wonkwang University) Lee, Ho Sub (College of Korean Medicine, Wonkwang University) |
1 | Lee, S.J., Lee, M.J., Ko, Y.J., Choi, H.R., Jeong, J.T., Choi, K.M., Cha, J.D., Hwang, S.M., Jung, H.K., Park, J.H., Lee, T.B. Effects of Extracts of Unripe Black Raspberry and Red Ginseng on Cholesterol Synthesis. Korean J. Food. Sci.. Technol. 45: 628-635, 2013. DOI ScienceOn |
2 | Yang, H.M., Oh, S.M., Lim, S.S., Shin, H.K., Oh, Y.S., Kim, J.K. Antiinflammatory activities of Rubus coreanus depend on the degree of fruit ripening. Phytother. Res. 22: 102-107, 2008. DOI ScienceOn |
3 | Hajnal, A., Covasa, M., Bello, N.T. Altered taste sensitivity in obese, prediabetic OLETF rats lacking CCK-1 receptors. Am. J. Physiol. Regul. Integr. Comp. Physiol. 289: R1675-R1686, 2005. DOI ScienceOn |
4 | Nishimatsu, H., Suzuki, E., Satonaka, H., Takeda, R., Omata, M., Fujita, T., Nagai, R., Kitamura, T., Hirata, Y. Endothelial dysfunction and hypercontractility of vascular myocytes are ameliorated by fluvastatin in obese Zucker rats. Am. J. Physiol. Heart. Circ. Physiol.. 288: 1770-1776, 2005. DOI ScienceOn |
5 | Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y. Increased oxidative stress in obesity and its impact on metabolic syndrome. J. Clin. Invest. 114: 1752-1761, 2004. DOI ScienceOn |
6 | Johnson, J.L. Matrix metalloproteinases:influence on smooth muscle cells and atherosclerotic plaque stability. Expert. Rev. Cardiovasc. Ther. 5: 265-282, 2007. DOI ScienceOn |
7 | Li, G., Sanders, J.M., Phan, E.T., Ley, K., Sarembock, I.J. Arterial macrophages and regenerating endothelial cells express P-selectin in atherosclerosis-prone apolipoprotein E-deficient mice. Am. J. Pathol. 167: 1511-1518, 2005. DOI ScienceOn |
8 | Ilan, E., Tirosh, O., Madar, Z. Triacylglycerol-mediated oxidative stress inhibits nitric oxide production in rat isolated hepatocytes. J. Nutr. 135: 2090-2095, 2005. |
9 | Busse, R., I, Fleming. Endothelial dysfunction in atherosclerosis. J. Vasc. Res. 33: 181-194, 1996. DOI ScienceOn |
10 | Kim, S.H., Kang, K.W., Kim K.W., Kim., N.D. Procyanidins in crataegus extract evoke endothelium-dependent vasorelaxation in rat aorta. Life sci. 67: 121-131, 2000. DOI ScienceOn |
11 | Yamamoto, Y., Oue, E. Antihypertensive effect of quercetin in rats fed with a high-fat high-sucrose diet. Biosci. Biotechnol. Biochem. 70: 933-939, 2006. DOI ScienceOn |
12 | Wang, S.Y., Lin, H.S.. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J. Agr. Food Chem. 48: 140-146, 2000. DOI ScienceOn |
13 | Jeong, J.H., Jung, H.N., Lee, S.R., Lee, H..J., Hwang, K.T., Kim, T.Y. Antioxidant, anti-proliferative and anti-inflammatory activities of the extracts from black raspberry fruits and wine. Food Chem. 123: 338-344, 2010. DOI ScienceOn |
14 | Kwon, K.H., Cha, W.S., Kim, D.C., Shin, H.J. 2006. A research and application of active ingredients in Bokbunja (RubuscoreanusMiquel). Korean J. Biotechnol. Bioeng. 21: 405-409, 2006. |
15 | Zhang, Z., Knobloch, T.J., Seamon, L.G., Stoner, G.D., Cohn, D.E., Paskett, E.D., Fowler, J.M., Weghorst, C.M. A black raspberry extract inhibits proliferation and regulates apoptosis in cervical cancer cells. Gynecol. Oncol. 123: 401-406, 2011. DOI ScienceOn |
16 | Lee, J.W., Do, J.H. Determination of total phenolic compounds from the fruit of Rubus coreanum and antioxidative activity. J. Korean Soc. Food Sci. Nutr. 29: 943-947, 2000. |
17 | Kim, T.G., Park, M.S., Han, H.M., Kang, S.Y., Jung, K.K., Pheu, H.M., Kim, S.H. Inhibitory effects of Terminalia chebula, Sanguisorba officinalis, Rubus coreanus and Rheum palmatum on hepatitis B virus replicationin HepG22.2.15cells. Yakhak Hoeji 43: 458-463, 1999. |
18 | Egan BM, Greene EL, Goodfriend TL. Insulin resistance and cardiovascular disease. Am J Hypertens. 14: S116-125, 2001. DOI ScienceOn |
19 | Grundy SM. Obesity, metabolic syndrome, and coronary atherosclerosis. Circulation. 105: 2696-2698, 2002. DOI ScienceOn |
20 | Krotkiewski, M., Björntorp, P., Sjöström, L., Smith, U. Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution. J. Clin. Invest. 72: 1150-1162, 1983. DOI ScienceOn |
21 | Quagliaro, L., Piconi, L., Assaloni, R., Da, Ros, R., Maier, A., Zuodar, G., Schreyer, S.A., Vick, C., Lystig, T.C., Mystkowski, P., LeBoeuf, R.C. LDL receptor but not apolipoprotein E deficiency increases diet-induced obesity and diabetes in mice. Am. J. Physiol. Endocrinol. Metab. 282: 207-214, 2002. |
22 | Journal of the American Medical Association (JAMA). National Cholesterol Education Program: Executive summary of the third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation and treatment of high blood cholesterol in adults (adult treatment panel Ⅲ). Circulation. 285: 2488-2497, 2001. |
23 | Report on National health and nutrition survey. Ministry of health and welfare 2007(Korean). |
24 | Sharma, A.M. Adipose tissue: a mediator of cardiovascular risk. Int. J. Obes. Relat. Metab. Disord. 4: S5-S7, 2002. DOI |
25 | Yotsumoto, H., Yanagita, T., Yamamoto, K., Ogawa, Y., Cha, J.Y., Mori, Y. Inhibitory effect of Oren-Gedoku-to and its components on cholesteryl ester synthesis in cultured human hepatocyte HepG2 cells: Evidence from the cultured HepG2 cells and in vitro assay of ACAT. Planta. Medica. 63: 141-145, 1997. DOI ScienceOn |
26 | Miettinen, T.A. Cholesterol absorption inhibition: A strategy for cholesterol-lowering therapy. Int. J. Clin. Pract. 55: 710-716, 2001. |
27 | Shin, M.K., Han, S.H. Effects of methanol extracts from bamboo(Pseudosasa japonica Makino) leaves extracts on lipid metabolism in rats fed high fat and high cholesterol diet. Korean J. Food Culture. 17: 30-36, 2002. |
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