• 제목/요약/키워드: Wang chong

검색결과 140건 처리시간 0.034초

Galectin-9 Acts as a Prognostic Factor with Antimetastatic Potential in Hepatocellular Carcinoma

  • Zhang, Zhao-Yang;Dong, Jia-Hong;Chen, Yong-Wei;Wang, Xian-Qiang;Li, Chong-Hui;Wang, Jian;Wang, Guo-Qiang;Li, Hai-Lin;Wang, Xue-Dong
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권6호
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    • pp.2503-2509
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    • 2012
  • Considerable research has been conducted concerning galectin-9 and carcinomas, but little information is available about any relation with the hepatocellular carcinoma. In this study, we employed a small interfering RNA (siRNA) targeting galectin-9 to down-regulate the expression in HepG2 cells. As a result, after galectin-9 expression was reduced, cell aggregation was suppressed, while other behaviour such as the proliferation, adhesion and invasion to ECM, cell-endothelial adhesion and transendothelial invasion of the cells were markedly enhanced. When tumors of 200 patients with hepatocellular carcinoma were tested for galectin-9 expression by immunohistochemistry, binding levels demonstrated intimate correlations with the histopathologic grade, lymph node metastasis, vascular invasion and intrahepatic metastasis (P<0.05). Moreover, survival analysis indicated that patients with galectin-9 expression had much longer survival time than those with negative lesions, and the Log-rank test indicated that this difference was statistical significant (P<0.0001). The Cox proportional hazards model suggested that negative galectin-9 expression in hepatocellular carcinoma represented a significant risk factor for patient survival. We propose that galectin-9 might be a new prognostic factor with antimetastatic potential in patients with hepatocellular carcinoma.

전자기 과도현상 해석과 고조파 평가를 위한 S영역 주파수 의존 등가시스템 개발 (S-Domain Frequency Dependent Network Equivalent for Electromagnetic Transient and Harmonic Assessment)

  • 왕용필;정형환;이준탁;한형주;김해재;정동일;곽노홍
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2006년도 제37회 하계학술대회 논문집 A
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    • pp.143-144
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    • 2006
  • The recent power systems are very complex and to model them completely is impractical for analysis of electromagnetic transient Therefore areas outside the immediate area of interest must be represented by some form of Frequency Dependent Network Equivalent (FDNE). In this paper a method for developing Frequency Dependent Network Equivalent (FDNE) using S-domain rational Function Fitting is presented and demonstrated. The FDNE is generated by Linearized Least Squares Fitting(LSF) of the frequency response of a S-domain formulation. This Three-port FDNE have been applied to the test AC power system. The electromagnetic transient package PSCAD/EMTDC is used to assess the transient response of the Three-port FDNE developed under different condition. The study results have indicated the robustness and accuracy of Three-port FDNE for analisys of electromagnetic transient and harmonic assessment.

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Paraquat중독(中毒) 치험(治驗) 3례(例) (Clinical Investigation of Patients with Acute Paraquat Poisoning and Case Reports Who Survived with Oriental Medical Treatment)

  • 박재현
    • 대한한의학회지
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    • 제15권2호
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    • pp.132-142
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    • 1994
  • Paraquat has been widely used as a herbicide in Korea since 1970. Human ingestion results in transient impairment of liver and kidney function and a characteristically respiratory failure with a high mortality rate. Clinical investigation and Oriental Medical Treatment were done on 3 cases of paraquat poisoning admitted to the department of 1st Internal Medicine. Kyung San University Oriental Medical Hospital from August 1991 to December 1992. and following results were obtained. The symptoms of paraquat poisoning can be regarded as Sim hua chi song(心火熾盛), Kan hua sang yom(肝火上炎). um hu hua wang(陰虛火旺), Kan tam sup yol(肝膽濕熱), Yang myong yol tok(陽明熱毒) in Oriental Medicine. and the principle of treatment for paraquat poisoning can be applicable to Chong yol Ii sop(淸熱利濕), Chong yol hae tok(淸熱解毒). Sa ha hae tok(瀉下解毒). Ja um kang hua(滋陰降火) and so on. Three cases were treated by HuangYonHaeTokTang(黃蓮解毒湯) and KamDuTang(甘豆湯): all of them have survived without complications. According to the result above, it suggests that determination of treatment based on the differentiation of symptoms and signs(Pyon jung si chi ;辨證施治) of Oriental Medicine may prove to be helpful in saving lives of patients with paraquat poisoning.

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A Study on the Causal Relationship between Logistics Infrastructure and Economic Growth: Empirical Evidence in Korea

  • Wang, Chao;Kim, Yul-Seong;Wang, Chong;Kim, Chi Yeol
    • Journal of Korea Trade
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    • 제25권1호
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    • pp.18-33
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    • 2021
  • Purpose - This paper investigates the causal relationship between logistics infrastructure development and the economic growth of Korea. Considering the industrial and economic structure of Korea, it is likely that logistics infrastructure is positively associated with the economic growth of the country. Design/methodology - The causal relationship between logistics infrastructure and economic development is estimated using Vector Autoregressive (VAR) and Vector Error Correction Model (VECM) considering long-run equilibrium between the two factors. To this end, a dataset consisting of 7 logistics infrastructure proxies and 5 economic growth indicators covering the period of 1990-2017 is used. Findings - It was found that causality, in general, runs from logistics infrastructure development to economic growth. Specifically, the results indicate that maritime transport is positively associated with the economic growth of Korea in terms of GDP and international trade. In addition, other modes of transport also have a positive impact on either the GDP or international trade of Korea. Originality/value - While existing studies in this area are based on either regional observations or a specific mode of transport, this study presents empirical evidence on causality between logistics infrastructure and the economic growth of Korea using a more comprehensive dataset. In addition, the findings in this paper can provide valuable implications for transport infrastructure development policies.

Synthesis and Properties of Liquid Crystalline Polyesters with Banana-Shaped Mesogens

  • Kwon, Myeong-Hoon;Kim, Sea-Yun;Choi, E-Joon;Lee, Jong-Chan;Zin, Wang-Cheol;Lee, Chong-Kwang
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2004년도 Asia Display / IMID 04
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    • pp.1223-1224
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    • 2004
  • A series of LC polyesters containing banana-shaped mesogen and flexible spacer were synthesized. Their structures were identified by FT/IR- and NMR-spectrometry. Thermal and mesomorphic properties were investigated by using DSC and polarizing microsope. Structure of mesophase was investigated by using x-ray diffractimetry.

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70W CDM 램프용 전자식 안정기 설계 (Design of the Electric Ballast for 70W CDM Lamp)

  • 최현희;최왕섭;박종연
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2009년도 제40회 하계학술대회
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    • pp.940_941
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    • 2009
  • Dual Buck Inverter구조를 가지는 70W CDM 램프용 전자식 안정기의 제어기를 설계하였다. 전자식 안정기는 EMI filter, Active PFC, Dual Buck Inverter, Igniter, SMPS로 구성 된다. 제어기는 크게 2개로 구분 할 수 있다. MC33262를 이용하여 Inverter의 전압, 전류를 센싱 받아 70kHz의 Zero Voltage Switching을 위한 제어기와 시간의 경과에 따라 PFC의 출력 전압 제어, Ignition Pulse 제어 및 무부하 보호를 위한 제어기로 구성되어 있다. 본 논문은 ATmega8을 이용하여 제어기를 설계하였고 실험으로 시간의 경광 따른 안정기의 제어가 안정적인 동작을 하고 있음을 증명하였다.

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Bioactive Metabolites from the Brittle Star Ophioplocus japonicus

  • Wang, Wei-Hong;Hong, Jong-Ki;Lee, Chong-Ok;Cho, Hee-Young;Shin, Sook;Jung, Jee-H.
    • Natural Product Sciences
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    • 제10권6호
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    • pp.253-261
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    • 2004
  • Ten terpenes (1-10), two sterols (11 and 12), and two unusual phenylpropanoids (13 and 14) were isolated from the brittle star Ophioplocus japonicus (Family Ophiuridae). Their structures were identified by analyses of the spectral data and by comparison with the literature data. The terpenes (1-10) and phenylpropanoids (13 and 14) are first encountered in brittle stars. These compounds were evaluated for cytotoxicity against a small panel of human solid tumor cell lines. Compounds 6-10 and 14 displayed moderate to significant cytotoxicity. The compounds were evaluated for antibacterial activity against 20 clinically isolated strains. Compound 5 exhibited antibacterial activities against three Streptococcus and three Staphylococcus strains.

Minimally Invasive Suturectomy and Postoperative Helmet Therapy : Advantages and Limitations

  • Chong, Sangjoon;Wang, Kyu-Chang;Phi, Ji Hoon;Lee, Ji Yeoun;Kim, Seung-Ki
    • Journal of Korean Neurosurgical Society
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    • 제59권3호
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    • pp.227-232
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    • 2016
  • Various operative techniques are available for the treatment of craniosynostosis. The patient's age at presentation is one of the most important factors in the determination of the surgical modality. Minimally invasive suturectomy and postoperative helmet therapy may be performed for relatively young infants, whose age is younger than 6 months. It relies upon the potential for rapid brain growth in this age group. Its minimal invasiveness is also advantageous. In this article, we review the advantages and limitations of minimally invasive suturectomy followed by helmet therapy for the treatment of craniosynostosis.