• Journal of Life Science
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• v.16 no.3 s.76
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• pp.454-458
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• 2006

HSF1 is the heat shock transcription factor in Saccharomyces cerevisiae. S. cerevisiae KNU5377 can ferment at high temperature such as $40^{\b{o}}C$. We have been the subjects of intense study because Hsf1p mediates gene expression not only to heat shock, but to a variety of cellular and environmental stress challenges. Basing these facts, we firstly tried to construct the hsf1 gene-deleted mutant. PCR-method for fast production of gene disruption cassette was introduced in a thermotolerant yeast S. cerevisiae KNU5377, which allowed the addition of short flanking homology region as short as 45 bp suffice to mediate homologous recombination to kanMX module. Such a cassette is composed of linking genomic DNA of target gene to the selectable marker kanMX4 that confers geneticin (G418) resistance in yeast. That module is extensively used for PCR-based gene replacement of target gene in the laboratory strains. We describe here the generation of hsf1 gene disruption construction using PCR product of selectable marker with primers that provide homology to the hsf1 gene following separation of haploid strain in wild type yeast S. cerevisiae KNU5377. Yeast deletion overview containing replace cassette module, deletion mutant construction and strain confirmation in this study used Saccharomyces Genome Deletion Project (http:://www-sequence.standard.edu/group/yeast_deletion_project). This mutant by genetic manipulation of wild type yeast KNU5377 strain will provide a good system for analyzing the research of the molecular biology underlying their physiology and metabolic process under fermentation and improvement of their fermentative properties.

• Journal of Radiation Protection and Research
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• v.39 no.1
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• pp.30-37
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• 2014

Recently High-Definition Reference Korean-Man (HDRK-Man) and High-Definition Reference Korean-Woman (HDRK-Woman) were constructed in Korea. The HDRK phantoms were designed to represent respectively reference Korean male and female to calculate effective doses for Korean by performing Monte Carlo dose calculation. However, the Monte Carlo dose calculation requires detailed knowledge on computational human phantoms and Monte Carlo simulation technique which regular researchers in radiation protection dosimetry and practicing health physicists do not have. Recently the UFPE (Federal University of Pernambuco) research group has developed, and opened to public, an online Monte Carlo dose calculation system called CALDOSE_X(www.caldose.org). By using the CALDOSE_X, one can easily perform Monte Carlo dose calculations. However, the CALDOSE_X used caucasian phantoms to calculate organ doses or effective doses which are limited for Korean. The present study developed an online reference Korean dose calculation system which can be used to calculate effective doses for Korean.

• Journal of Korean Clinical Health Science
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• v.5 no.1
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• pp.790-802
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• 2017

Purpose. This study was designed to analyze recent trends in Children Art Therapy Program Intervention research in Korea and suggest future research directions in this area. Methods. Studies(29) selected from http://www.riss4u.net for last 15 year were used. They were analyzed by publication type, field and design of the study, study participants and outcome variables used in intervention studies. Results. 1. As for academic field, there are 15 art therapy academic journals(51.72%), which made up the largest proportion. 2. As for subjects of the study, there are 17 articles of Elementary (58.6%) education, which made up the largest proportion. As for the subjects of sex, 8 articles (27.59%) are for male students, 7 (24.14%) articles are for female students and 14 articles (48.28.%) are for both male and female students. 3. As for 7 articles of Art therapy(24.14%), 7 articles of Group Art therapy (24.14%) made up the largest proporton 4. As for the intervention study method according to the subjects of suicide intervention program, there are 15 articles of monoclonal Pre and post design (51.72%),which made up the largest proportion. 5. As for the sample size, there were 16.79 persons in the treatment group on average, 13.28 persons in the control group have average and the total persons were 10 on average. The treatment period was 12 weeks on average and the average number of treatment times was 18. The places of treatment were 3 schools (10.38%), which made up the largest proportion. 19. The results of the experimental study support the research hypothesis of all 29 programs. Conclusions. As the above, the studies on the art therapy intervention program for children are increasing but the subjects are overly weighted toward elementary school students. Although the content of the art therapy intervention program was varied, it was found that the development of the program using various art media which can induce the motivation of the child was lacking. In addition, the place of experimental mediation was concentrated on psychology center as 12(41.38%), indicating that there are not enough places to connect with community organizations such as schools and hospitals. The variables of experimental study were focused on psychological variables and it was found that there were insufficient application of various variables including coping method, social support, and physiological variables.

• Journal of Pharmacopuncture
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• v.11 no.3
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• pp.113-122
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• 2008

Objective: The purpose of this study was to invigorate the use of infrared thermal imaging apparatus as a diagnostic tool in Oriental medicine by providing standard temperature on specific acupoints. Methods: Subjects for the study was recruited through an advertisement in the school homepage(www.sangji.ac.kr) explaining the objectives and methods. 100 volunteers agreeing to terms were selected and measured the full body thermal image. Common acupoints used in the clinical surrounding were chosen and final 63 acupoints were selected for the measurement. Male/female and right/left readings were obtained for the analysis. Results: Following results were obtained from analyzing the body temperature of 50 male subjects and 50 female subjects 1. Subjects participating in the study ranged from 19 years of age to 44 years. Median male age at $26.86{\pm}6.02$ and female age at $22.88{\pm}2.74$, respectively. 2. For all acupoints, no significant differences were witnessed between the gender and right, left side of the body. 3. 10 acupoints from the facial region(18 bilateral), 8 acupoints from the chest/abdomen region(10 bilateral), 6 acupoints from the back region(11 bilateral), 17 acupoints from the upper extremity(34 bilateral), and 22 acupoints from the lower extremity(44 bilateral) were chosen. 4. In the facial region, BL2 showed the highest temperature and GV26 showed the lowest. 5. In the chest/abdomen region, CV22 showed the highest temperature and CV6 showed the lowest. 6. In the back region, GV14 showed the highest temperature and BL23 showed the lowest. 7. In the upper extremity region, jianqian(extra point) showed the highest temperature and baxie(extra point) showed the lowest. 8. In the lower extremity region, KI1 and bafeng(extra point) shoed the highest temperature and BL40 showed the lowest. Conclusions: Based on the standard body temperature measured on specific acupoints throughout the body, we hope these findings can trigger further studies on applications of infrared thermal imaging and clinical usage in the field of oriental medicine.

• Vending industry
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• v.3 no.1 s.9
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• pp.64-69
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• 2004

고수익을 미끼로 한 자판기 분양사기가 최근 급증하고 있어 큰 문제가 되고 있다. 무조건 자판기 수익성만을 과대포장하여 투자자들의 `묻지마` 투자를 유도한 후 돈만 챙기고 사업에서 손을 떼어버리는 사기행각은 그 피해대상이 대부분 서민이라는 점에서 문제의 심각성을 더한다. 자판기가 불법 자금 모집을 통해 사기의 대상으로 외부 인식이 악화되어 버린다면 자판기 산업의 입지 역시 크게 좁혀 질 수 밖에 없다. 자판기 품목에 있어서는 불법자금모집의 대표적인 사례가 되는 경우는 확정수익을 보장한다며 투자자를 모집하는 경우이다. 그 후 일정기간동안 수익을 보장하며 투자자를 안심시킨 다음 일순간 돌변하여 자금을 챙겨 잠적을 하는 수순을 밝는다. 선의의 투자자들은 이럴 경우 엄청난 피해를 입게 되는 게 보통이다. 대개의 경우 기계 1~2대의 소량물량이 아닌 5대~l0대 단위의 투자를 유도하기 때문이다. 이제는 자판기 산업에 있어 이러한 악성 불법자금 모집업체들이 근절되어야 한다. 이 불법 사기행각의 대상이 더 이상 자판기 분야에 발을 붙이지 못하도록 하는 제도적 비책이 시급히 강구 되어야 한다. 이러한 가운데 금융감독원 비은행감독국 비제도금융조사팀에서는 올들어 지난 9월말까지 고수익을 미끼로 투자자금을 모집하다가 금감원에 적발된 유사 금융업체 85개사 명단을 사법당국에 통보했다. 불법자금모집 업체들이 투자자들을 유혹하기위해 미끼로 내세운 사업을 종류별로 보면 자판기, 게임기, 컴퓨터단말기 등 특정상품 운영권 제공이 29개사로 가장 많고, 사이버 쇼핑몰 및 인터넷사업(18개사), 납골당 등 부동산 투자(12개사), 영화등 문화 및 레저사업(10개사), 영화문화 및 레저산업(10개사), 벤처투자사(9개사) 등이었다. 자판기 분야에 있어서는 주로 성인용품자판기, 복권자판기 등의 품목이 불법자금 모집의 집중 타킷이 되었다. 금감원은 최근들어 유사 금융업체의 자금모집이 전문가도 속을 정도로 지능화하고 있다며 개인투자자들이 피해를 예방할 수 있는 불법업체 식별법을 금감원 인터넷 사이트(www.fss.or.kr)에 게시했다. 금감원은 특히 사업현황에 대해 지나치게 보안을 유지하는 업체, 1백$\%$이상의 터무니없는 고수익을 보장한다고 광고하는 업체, 제도권 금융회사의 지급보증을 강조하는 업체에 대해서는 투자에 앞서 금감원이나 업종 관련 정부당국에 사실여부를 확인해 보고 투자여부를 결정하라고 통보했다. 아울러 금감원은 금융소비자들이나 자판기 업계에서 불법자금 모집업체를 발견하여 전화(02-3786-8155~9)나 인터넷소비자 보호센터와 경찰에 신고해줄 것을 요청했다. 이제는 산업계도 더 이상 자판기 분야의 불법자금업체를 방치하지 말고 적극적인 금감원 신고를 통해 시장을 정화할 수 있게 해야 한다. 미꾸라지 한두마리가 온 개천 물 다 흐려놓는 이치처럼 자판기불법자금업체들로 인해 전체 산업에 미치는 영향이 실로 심각함을 인식해야 할 때이다. 금호 산업정보에서는 산업계에서 불법자금업체 근절에 많은 관심을 가질 수 있게 하기 위해 금융감독원 비은행감독국 비제도금융조사팀에서 배포한 $\ulcorner$불법자금 모집업체 고수익 보장 유혹에 주의$\lrcorner$ 에 대한 보도자료의 세부내용을 게재한다.

• Proceedings of the Korea Water Resources Association Conference
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• 2006.05a
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• pp.1116-1120
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• 2006

하천주변 저지대에 주택이나 공장 등의 시설물 집중과 산지의 개발 및 인구 집중으로 인한 도시화 지역의 증가로 홍수 피해는 더욱 커지고 있다. 특히, 상습침수지구의 주민들은 항상 재해로부터 위험을 느끼고 있으므로 새로운 재해관리체계를 구축하여 이에 대한 확고한 대책이 필요하다. 최근 인터넷 사용의 증가로 많은 사용자들이 웹을 통해 다양한 데이터를 공유하고 있으며, 이러한 추세는 더욱 더 증가할 것이다. 인터넷은 다양한 정보를 네트워크를 통해 사용자에게 실시간으로 제공하고 있으며, 통신기술의 발전, 네트워크 통합화 속에서 그 내용과 방식이 더욱 다양해지고 있다. GIS분야에 있어서도 인터넷 네트워크를 이용하여 분산되어 있는 많은 조직이나 사용자들에게 그 기능과 서비스를 제공하는 추세로 바뀌고 있다. Internet GIS는 원격 지리정보 데이타에 대한 접근, 전송, 분석 및 GIS를 표현하는 수단으로 인터넷을 이용하는 특별한 GIS 도구이다. Internet GIS는 전통적인 GIS 소프트웨어가 가지고 있는 대부분의 기능은 물론 인터넷 및 그와 관련된 WWW 및 FTP 프로토콜의 장점을 가지는 부가적인 기능들을 포함할 수 있다. 이들 부가적인 기능은 원격 데이타 및 응용 프로그램의 교환, 지역 컴퓨터에 GIS 응용 프로그램 없이 GIS 분석 기능을 수행, 인터넷상에서 상호작용하는 지도 및 데이타를 표현하는 기능들을 포함한다. Internet GIS는 객체지향적이고 상호운영적이며, 분산적이라는 주요한 특징을 갖는다. 인터넷에서 각각의 GIS 데이타 및 기능성은 하나의 객체로서 서로 다른 서버에 위치하며 필요시 조합 또는 통합되어 운영된다. Internet GIS를 이용한 상습침수지구 지역정보 제공사이트를 구축하기 위해서는 인터넷으로 서비스 할 수 있는 인터넷용 상습침수지구 GIS기본도를 구축이 필요하다. 인터넷 서비스를 위한 상습침수지구 기본도는 또 다른 형태의 주제도라고 볼 수 있으며, 이를 구축하기 위해서는 자료변환 및 가공이 필요하다. 즉, 각 상습침수지구에 필요한 지형도는 국립지리원에서 제작된 1:5,000 수치지형도가 있으나 이는 자료가 방대하고 상습침수지구에 필요하지 않은 자료들을 많이 포함하고 있으므로 상습침수지구의 데이터를 인터넷을 통해 서비스하기 위해서는 많은 불필요한 레이어의 삭제, 서비스 속도를 고려한 데이터의 일반화작업, 지도의 축소.확대 등 자료제공 방식에 따른 작업 그리고 가시성을 고려한 심볼 및 색채 디자인 등의 작업이 수반되어야 하며, 이들을 고려한 인터넷용 GIS기본도를 신규 제작한다. 상습침수지구와 관련된 각종 GIS데이타와 각 기관이 보유하고 있는 공공정보 가운데 공간정보와 연계되어야 하는 자료를 인터넷 GIS를 이용하여 효율적으로 관리하기 위해서는 단계별 구축전략이 필요하다. 따라서 본 논문에서는 인터넷 GIS를 이용하여 상습침수구역관련 정보를 검색, 처리 및 분석할 수 있는 상습침수 구역 종합정보화 시스템을 구축토록 하였다.

• Journal of Intelligence and Information Systems
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• v.8 no.1
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• pp.141-157
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• 2002

extensible Markup Language (XML) is a new markup language for data exchange on the Internet. In this paper, we propose a language extensible Rule Markup Language (XRML) which is an extension of XML. The implicit rules embedded in the Web pages should be identifiable, interchangeable with structured rule format, and finally accessible by various applications. It is possible to realize by using XRML. In this light, Web based Knowledge Management Systems (KMS) can be integrated with rule-based expert systems. To meet this end, we propose the six design criteria: Expressional Completeness, Relevance Linkability, Polymorphous Consistency, Applicative Universality, Knowledge Integrability and Interoperability. Furthermore, we propose three components such as RIML (Rule Identification Markup Language), RSML (Rule Structure Markup Language) and RTML (Rule Triggering Markup Language), and the Document Type Definition DTD). We have designed the XRML version 0.5 as illustrated above, and developed its prototype named Form/XRML which is an automated form processing for disbursement of the research fund in the Korea Advanced Institute of Science and Technology (KAISI). Since XRML allows both human and software agent to use the rules, there is huge application potential. We expect that XRML can contribute to the progress of Semantic Web platforms making knowledge management and e-commerce more intelligent. Since there are many emerging research groups and vendors who investigate this issue, it will not take long to see XRML commercial products. Matured XRML applications may change the way of designing information and knowledge systems in the near future.

• Journal of Intelligence and Information Systems
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• v.9 no.1
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• pp.91-107
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• 2003

In the conduct of this study, a web-enabled healthcare system for the management of hypertension was implemented through a hyperlink-based inference approach. The hyperlink-based inference platform was implemented using the hypertext capacity of HTML which ensured accessibility, multimedia facilities, fast response, stability, ease of use and upgrade, and platform independency of expert systems. Many HTML documents, which are hyperlinked to each other based on expert rules, were uploaded beforehand to perform the hyperlink-based inference. The HTML documents were uploaded and maintained automatically by our proprietary tool called the Web-Based Inference System (WeBIS) that supports a graphical user interface (GUI) for the input and edit of decision graphs. Nevertheless, the editing task of the decision graph using the GUI tool is a time consuming and tedious chore when the knowledge engineer must perform it manually. Accordingly, this research implemented an automatic generator of the decision graph for the management of hypertension. As a result, this research suggests a methodology for the development of Web-enabled healthcare systems using the hyperlink-based inference approach and, as an example, implements a Web-enabled healthcare system for hypertension, a platform which performed especially well in the areas of speed and stability.

• The KIPS Transactions:PartD
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• v.9D no.5
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• pp.801-812
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• 2002

On-line reorganization in a shared nothing database cluster is crucial to the performance of the database system in a dynamic environment like WWW where the number of users grows rapidly and changing access patterns may exhibit high skew. In the existing method of on-line reorganization have a drawback that needs excessive data migrations in case more than two nodes within a cluster have overload at the same time. In this paper, we propose an advanced B$^{+}$ tree based on-line reorganization method that solves data skew on multi-nodes. Our method facilitates fast and efficient data migration by including spare nodes that are added to cluster through on-line scaling. Also we apply CSB$^{+}$ tree (Cache Sensitive B$^{+}$ tree) to our method instead of B$^{+}$ tree for fast select and update queries. We conducted performance study and implemented the method on Ultra Fault-Tolerant Database Cluster developed for high scalability and availability. Empirical results demonstrate that our proposed method is indeed effective and fast than the existing method. method.

• Journal of KIISE:Software and Applications
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• v.31 no.9
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• pp.1226-1232
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• 2004

Biometric authentication is rising technology for the security market of the next generation. But most of biometric systems are developed using only one of various biological features. Recently, there is a vigorous research for the standardization of various biometric systems. In this paper, we propose a web-based authentication system using three other verifiers based on functional, parametric, and structural approaches for one biometrics of handwritten signature, which is conformable to a specification of BioAPI introduced by BioAPI Consortium for a standardization of biometric technology. This system is developed with a client-server structure, and clients and servers consist of three layers according to the BioAPI structure. The proposed neb-based multiple authentication system of one biometrics can be used to highly increase confidence degree of authentication without additional several biological measurements, although rejection rate is a little increased. That is, the false accept rate(FAR) decreases on the scale of about 1:40,000, although false reject rate(FRR) increases about 2.7 times in the case of combining above three signature verifiers. So the proposed approach can be used as an effective identification method on the internet of an open network. Also, it can be easily extended to a security system using multimodal biometrics.