• Title/Summary/Keyword: WR

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Effects of Sansachunghyul-tang (SCT) on blood cholesterol levels in Triton WR1339-induced hyperlipidemic rats (산사청혈탕(山楂淸血湯)이 Triton WR1339로 유발된 흰쥐의 고지혈증(高脂血症)에 미치는 영향)

  • Chang, Mun Seog;Joo, Seung-Hun;Kim, Eun Yi;Park, Seong Kyu
    • Herbal Formula Science
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    • v.27 no.1
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    • pp.1-6
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    • 2019
  • Objectives : Sansachunghyul-tang (山楂淸血湯) is a new formula consist of some herbs to treatment of hyperlipidemia. The lipid-lowering effects of the water extract of Sansachunghyul-tang (SCT) were examined using Triton WR1339-induced hyperlipidemic rats. Methods : Hyperlipidemia was induced by intravenous injection of Triton WR1339 (tyloxapol) at 200 mg/kg body weight. Four groups of experimental animals were used: normal, control, and two sample groups. Sample groups were injected with SCT (100 and 1000 mg/kg) for 7 days. Results : SCT produced statistically significant lowering effects on levels of total cholesterol (81.8 and 83.1%, p < 0.01, respectively), triglyceride (88.9 and 93.4%, p < 0.01, respectively), and phospholipid (86.7 and 94.3%, p < 0.01, respectively) than the control group. Taken together, SCT improved parameters of the HDL-cholesterol and LDL-cholesterol levels. Conclusions : In conclusion, These results suggest that SCT could act as a potent antihyperlipidemic in therapeutics for hyperlipidemia.

Between-and Within-person Variability of Nutrient Intake in 7-day weighed Food Records (7일 실측법에 의한 영양소섭취량의 개인간변이와 개인내변이)

  • 정해랑
    • Journal of Nutrition and Health
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    • v.25 no.2
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    • pp.179-186
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    • 1992
  • Dietary intakes of 57 college women were measured by 7-day weight food records(7WR) Nutrient intakes of 7WR were compared with results of using 1-day weighted food records(1WR) and 2-day weighed food records(2WR), 7WR were recorded for 7 consecutive days by subjects and its first two days were chosen to provide 1WR and 2WR Mean nutrient intakes of the group were not significantly different between 1WR or 2WRand 7WR. Within-person variations were found to be greater than between-person variations. The ratio of within- and between-person variability was lowest for the vitamin A and highest for the calcium. Data on 7WR were analyzed to estimate the number of recording days needed to ensure r$\geq$0.9 between observed and turn mean intakes. The 11 to 13 days needed for energy sugar protein and vitamin A and 20 days for calcium The results indicated that the number of days needed varied substantially among individuals for the same nutrient and within individuals for different nutrients.

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Experimental study on the effects of Luffae fasciculus vascularis(絲瓜絡) on hyperlipidemia (사과락(絲瓜絡)이 Triton Wr 투여로 유발되는 고지혈증(高脂血證) 예방에 미치는 영향에 대한 실험적 연구)

  • Lee Jeong-Seok;Soh Kyung-Sun;Jeong Chan-Gil
    • Journal of Society of Preventive Korean Medicine
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    • v.6 no.2
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    • pp.95-103
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    • 2002
  • In order to study the effect of Luffae fasciculus vascularis(絲瓜絡) on hyperlipidemia, experimental study was performed on Hyperlipidemia induced by Triton WR-1339. Also the level of Total cholesterol, Triglyceride, HDL-cholesterol, Phospholipid and LDL-cholesterol were measured. The results are summarized as follow: In the model of hyperlipidemia Rats induced by Triton WR-1339, luffae fasciculus vascularis(絲瓜絡) had significantly decreasing effects on total cholesterol, triglyceride, phospholipid, LDL-cholesterol in serum and increasing effects on HDL-cholesterol level in serum but were not significant. These results show that Luffae fasciculus vascularis(絲瓜絡) has significantly inhibitory effects on hyperlipidemia and that it could be clinically applied for hyperlipidemia.

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Protection of Saururus Chinensis Extract against Liver Oxidative Stress in Rats of Triton WR-1339-induced Hyperlipidemia

  • Kwon, Ryun Hee;Ha, Bae Jin
    • Toxicological Research
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    • v.30 no.4
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    • pp.291-296
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    • 2014
  • Saururus chinensis has been reported to contain compounds such as lignans, alkaloids, diterpenes, flavonoids, tannins, steroids, and lipids. Fermentation is commonly used to break down certain undesirable compounds, to induce effective microbial conversion, and to improve the potential nutraceutical values. Previous studies have reported that the fermentation process could modify naturally occurring constituents, including isoflavons, saponins, phytosterols, and phenols, and could enhance biological activities, specifically antioxidant and antimicrobial properties. The probiotic strains used for fermentation exert beneficial effects and are safe. In this study, the antioxidative effects of the Bacillus subtilis fermentation of Saururus chinensis were investigated in a rat model with Triton WR-1339-induced hyperlipidemia by comparing the measured antioxidative biological parameters of fermented Saururus chinensis extract to those of nonfermented Saururus chinensis extract. Fermentation played a more excellent role than nonfermentation in ultimately protecting the body from oxidative stress in the liver of the experimental rats with Triton WR-1339-induced hyperlipidemia.

Studies on the Antihypercholesterolemic Effects of Gamigwaruhaebaekwhanggum - Tang (가미과루해백황금탕의 항고지혈증 효과)

  • 정은아;김윤경;김남재;김동현;이상인
    • Biomolecules & Therapeutics
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    • v.9 no.2
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    • pp.104-111
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    • 2001
  • Gamigwaruhaebaekwhanggum-Tang (GGHWT) have been evaluated for antihyperlipidemic effects on experimental hyperlipidemic rats and mice induced by Triton WR-1339, com oil and high cholersterol-diet. Especially, GGHWT is formulated with Trichosanthis Fructus, Pinelliae Tuber, Aurantii Immaturus Fructus, Magnoliae Cortex, Allii Macrostemi Bulbuls, Cinnamomi Ramulus and Scutellariae Radix. Oral administration of GGHWT at 500 mg/kg/day for 3 days significantly inhibited the increase of serum triglyceride and LDL-cholesterol, liver triglyceride in hyperlipidemic rats induced by Triton WR-1339. And, GGHWT significantly inhibited the increase of serum triglyceride in hyperlipidemic rats induced by corn oil. Also, administration of GGHWT (500 mg/kg, once daily for 1 week, p.o.) prevented the increase of serum total cholesterol, triglyceride, LDL-cholesterol, liver total cholesterol and triglyceride in 1% cholesterol-diet fed mice. These results suggest that GGHWT is effective for the treatment of hyperlipidemia.

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The Preventive Effect of Bacillus polyfermenticus KJS-2 and Angelica gigas Nakai Extract on Triton WR-1339-induced Hyperlipidemia (Bacillus polyfermenticus KJS-2와 참당귀 추출물의 triton WR-1339 유발 고지혈증에 대한 예방효과)

  • Kim, Kang Min;Kim, Bo Seul;Kang, Jae Seon
    • Journal of Life Science
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    • v.28 no.6
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    • pp.726-732
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    • 2018
  • The purpose of this study was to investigate the effects of Bacillus polyfermenticus KJS-2 (B. polyfermenticus KJS-2) and Angelica gigas Nakai extracts (AGNE) on hyperlipidermia. The purity of the major decursin and decursinol angelate (D/DA) in the AGNE were analyzed at 78%. Increased concentrations of AGNE (0.1-20 mg/ml) showed a higher 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibition activity. Endospore-forming B. polyfermenticus KJS-2 ($1{\times}10^9CFU/ml$) exhibited good bile tolerance (0.3 mm) on an agar plate. An animal study was carried out using different groups, including a normal control, positive control (atorvastatin), negative control (triton WR-1339), AGNE group, B. polyfermenticus KJS-2 group, AGNE + B. polyfermenticus KJS-2 group, and Atorvastatin + AGNE + B. polyfermenticus KJS-2 group to determine the effect of hyperlipidemia. There were no significant changes in body weight, kidney weight, or liver weight except for the liver weight of the triton WR-1339-treated group. Groups with AGNE and B. polyfermenticus KJS-2 had increased HDL-cholesterol and decreased total cholesterol and triglycerides. The liver histopathological results also showed that all AGNE and B. polyfermenticus KJS-2-treated groups contained lower fat accumulation in the liver tissues. The findings of this study verified that AGNE and Endospore-forming B. polyfermenticus KJS-2 combination materials have a hyperlipidemic effect.

16-port Feed Waveguide Array for DBS Reception System Mounted on Vehicle (차량 탑재형 DBS 수신 시스템용 16 포트 급전 도파관 어레이)

  • Min, Gyeong-Sik;Kim, Dong-Cheol
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.39 no.2
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    • pp.92-100
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    • 2002
  • The 16-port feed waveguide array with inductive walls analyzed by Galerkin's method of moments are proposed for the DBS reception system mounted on vehicle. First of all, in order to verify the validity of electromagnetic analysis and design for a $\pi$-junction feed waveguide, it is designed and fabricated at DBS band. The measurement results of a $\pi$-junction feed waveguide agree well with the theoretical ones. Based on this design method, an array design for WR-90 standard waveguide is conducted. Since the width of a $\pi$-junction feed WR-90 standard waveguide is larger than a guided wave length in an array design, the difference of amplitude and phase of 8-port array are calculated 2.3 dB and 62 degrees, respectively. The bandwidth with return loss of -20 dB below is about 220 MHz and it doesn't satisfy DBS band. To solve this problem, we propose a novel design that the width of a $\pi$-junction feed waveguide equals to a guided wave length. By the proposed novel design for 8-port feed waveguide array, the difference of amplitude and phase are decreased 1 dB and 13 degrees, respectively. The broad bandwidth of 700 MHz is also realized. The size of 16-port waveguide away compared with WR-90 array is reduced about 10 cm. The measured antenna gain for the fabricated 16-port feed waveguide array is observed 24 dBi above at DBS band.

A Study on Millimeter Wave Power Amplifiers Using Spatial Combining (공간 결합을 이용한 밀리미터파 전력 증폭기에 관한 연구)

  • Ki, Hyeon-Cheol
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.17 no.4
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    • pp.77-82
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    • 2017
  • As frequencies increase to the millimeter wave bands the cross sections of wave guides become smaller than a few millimeters, which cause sapatial problems in realization of spatial combining power amplifiers. In this paper we intented to overcome the problem by widening the width of wave guides using horn antenna principles. We designed a widened rectangular wave guide for using in spatial combining power amplifier in 60GHz ISM band(57-64GHz), and we installed Antipodal transition in the widened wave guide, and then we characterized it as a spatial combining power amplifier. For the compatibility of WR15 standard wave guide, we widened the width of WR15 to 7mm using principle of H-plane sectoral horn antenna and then installed 3 slots of back to back Antipodal transition. The designed spatial combining power amplifier showed good characteristics of return loss less than -22.4dB and insertion loss less than 0.53dB. However, as widening the width of the wave guide, additional modes such as $TE_{20}$, $TE_{30}$ in addition to $TE_{10}$ were accurred in the bandwidth of WR15, which restricted the bandwidth and widening of the width of the wave guide.

Interactions in Massive Colliding Wind Binaries

  • Corcoran, Michael F.
    • Journal of Astronomy and Space Sciences
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    • v.29 no.1
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    • pp.93-96
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    • 2012
  • There are observational difficulties determining dynamical masses of binary star components in the upper HR diagram both due to the scarcity of massive binary systems and spectral and photometric contamination produced by the strong wind outflows in these systems. We discuss how variable X-ray emission in these systems produced by wind-wind collisions in massive binaries can be used to constrain the system parameters, with application to two important massive binaries, Eta Carinae and WR 140.

Object-Oriented Design Object Analyzer based on the WWW (WWW 기반의 객체지향 설계 정보 분석 도구)

  • 유정목;배명남;최동운;양재동
    • Proceedings of the Korean Information Science Society Conference
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    • 1998.10b
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    • pp.12-14
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    • 1998
  • 본 논문에서는 소프트웨서 개발 과정에서 얻은 설계정보들을 웹 위에서 참조하고 파악할 수 있도록 구축한 환경에 대해 기술한다. 이를 위해, 개발 과정에서 얻은 설계 정보들을 웹 검색 구조에 맞도록 변화하는 과정과, 여기에서 얻어진 여러 형식의 많은 정보들을 저장하고 유지하기 위한 웹 저장소(WR: Web Repository), 그리고 WR내에 구축된 분석 정보들을 보이고, 개발자의 요구에 따라 분석 정보들을 제어하기 방안을 설명하다. 개발 환경은 Solaris 2.5에서 Tcl/Tk와 C++를 활용하여 구현하며, 클라이언트의 애플릿(applet) 개발을 위해 tclet을 활용한다.